A lysophosphatidic acid receptor lacking the PDZ-binding domain is constitutively active and stimulates cell proliferation

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1783, Issue 5, 2008, Pages 748-759

  Shano, Shinya ^a   Hatanaka, Kazuki ^a   Ninose, Shinsuke ^a   Moriyama, Ryutaro ^a   Tsujiuchi, Toshifumi ^a   Fukushima, Nobuyuki ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

Akt; Lysophosphatidic acid receptor; Oncogenic signal; PDZ binding domain; Phosphoinositide 3 kinase; Rho

Indexed keywords

LYSOPHOSPHATIDIC ACID RECEPTOR; PDZ PROTEIN; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; RHO FACTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; MICE; PDZ DOMAINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, LYSOPHOSPHATIDIC ACID; RHO GTP-BINDING PROTEINS; SEQUENCE DELETION;

EID: 41949086804     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2007.11.013     Document Type: Article

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