The role of protein dynamics in the evolution of new enzyme function

Nature Chemical Biology

Volumn 12, Issue 11, 2016, Pages 944-950

  Campbell, Eleanor ^a   Kaltenbach, Miriam ^b,c   Correy, Galen J ^a   Carr, Paul D ^a   Porebski, Benjamin T ^d   Livingstone, Emma K ^a   Afriat Jurnou, Livnat ^a   Buckle, Ashley M ^d   Weik, Martin ^e   Hollfelder, Florian ^c   Tokuriki, Nobuhiko ^b   Jackson, Colin J ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d MONASH UNIVERSITY   (Australia)

^e UNIV GRENOBLE ALPES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; ARYLESTERASE; CARBOXYLESTERASE; PHOSPHOTRIESTERASE;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME CONFORMATION; HYDROLYSIS; MOLECULAR EVOLUTION; PRIORITY JOURNAL; PROTEIN FUNCTION; BIOCATALYSIS; CHEMISTRY; ENZYMOLOGY; METABOLISM; PROTEIN CONFORMATION; PSEUDOMONAS;

BIOCATALYSIS; CARBOXYLIC ESTER HYDROLASES; EVOLUTION, MOLECULAR; PHOSPHORIC TRIESTER HYDROLASES; PROTEIN CONFORMATION; PSEUDOMONAS;

EID: 84987641979     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.2175     Document Type: Article

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