Hitting a moving target?-Understanding how conformational diversity impacts enzymatic catalysis

Current Opinion in Chemical Biology

Volumn 14, Issue 5, 2010, Pages 634-635

  O'Brien, Patrick J ^a   Hollfelder, Florian ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Department of Biochemistry ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; EDITORIAL; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYMOLOGY;

BIOCATALYSIS; ENZYMES; MOVEMENT; PROTEIN CONFORMATION;

EID: 77957750113     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpa.2010.09.009     Document Type: Editorial

References (2)

1. Nagel Z.D., Klinman J.P. A 21st century revisionist's view at a turning point in enzymology. Nat Chem Biol 2009, 5:543-550.
2. Kamerlin S.C., Warshel A. At the dawn of the 21st century: is dynamics the missing link for understanding enzyme catalysis?. Proteins 2010, 78:1339-1375.