메뉴 건너뛰기




Volumn 7, Issue 30, 2016, Pages 47831-47847

Proteomic analyses of brain tumor cell lines amidst the unfolded protein response

Author keywords

Brain tumor; Glioma; Proteomics; Signaling; Unfolded protein response

Indexed keywords

BRAIN TUMOR CELL LINE; CANCER GRADING; CARCINOGENESIS; CASE REPORT; CELL SURVIVAL; CLASSIFICATION; GLIOMA CELL LINE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PROTEOMICS; STRESS; UNFOLDED PROTEIN RESPONSE; BRAIN TUMOR; GENETICS; GLIOMA; METABOLISM; PATHOLOGY; PROCEDURES; TUMOR CELL LINE;

EID: 84982834067     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.10032     Document Type: Article
Times cited : (4)

References (98)
  • 4
    • 80052713548 scopus 로고    scopus 로고
    • Genetic profile of astrocytic and oligodendroglial gliomas
    • Ohgaki H, Kleihues P. Genetic profile of astrocytic and oligodendroglial gliomas. Brain Tumor Pathol. 2011; 28:177-183.
    • (2011) Brain Tumor Pathol , vol.28 , pp. 177-183
    • Ohgaki, H.1    Kleihues, P.2
  • 6
    • 84893656213 scopus 로고    scopus 로고
    • Endoplasmic reticulum (ER) stress and hypoxia response pathways interact to potentiate hypoxia-inducible factor 1 (HIF-1) transcriptional activity on targets like vascular endothelial growth factor (VEGF)
    • Pereira ER, Frudd K, Awad W, Hendershot LM. Endoplasmic reticulum (ER) stress and hypoxia response pathways interact to potentiate hypoxia-inducible factor 1 (HIF-1) transcriptional activity on targets like vascular endothelial growth factor (VEGF). J Biol Chem. 2014; 289:3352-3364.
    • (2014) J Biol Chem , vol.289 , pp. 3352-3364
    • Pereira, E.R.1    Frudd, K.2    Awad, W.3    Hendershot, L.M.4
  • 8
    • 70349352744 scopus 로고    scopus 로고
    • Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase
    • Santos CX, Tanaka LY, Wosniak J, Laurindo FR. Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase. Antioxid Redox Signal. 2009; 11:2409-2427.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2409-2427
    • Santos, C.X.1    Tanaka, L.Y.2    Wosniak, J.3    Laurindo, F.R.4
  • 9
    • 84925324913 scopus 로고    scopus 로고
    • Calcium homeostasis and ER stress in control of autophagy in cancer cells
    • Kania E, Pajak B, Orzechowski A. Calcium homeostasis and ER stress in control of autophagy in cancer cells. BioMed research international. 2015; 2015:352794.
    • (2015) BioMed research international , vol.2015
    • Kania, E.1    Pajak, B.2    Orzechowski, A.3
  • 10
    • 84865245211 scopus 로고    scopus 로고
    • Unfolded protein response
    • Cao SS, Kaufman RJ. Unfolded protein response. Curr Biol. 2012; 22:R622-626.
    • (2012) Curr Biol , vol.22 , pp. R622-R626
    • Cao, S.S.1    Kaufman, R.J.2
  • 11
    • 85014875079 scopus 로고    scopus 로고
    • The unfolded protein response in glioblastomas: targetable or trouble?
    • Graner MW. The unfolded protein response in glioblastomas: targetable or trouble? Future Science OA. 2015; 1(2).
    • (2015) Future Science OA , vol.1 , Issue.2
    • Graner, M.W.1
  • 12
    • 84863740827 scopus 로고    scopus 로고
    • The impact of the unfolded protein response on human disease
    • Wang S, Kaufman RJ. The impact of the unfolded protein response on human disease. J Cell Biol. 2012; 197:857-867.
    • (2012) J Cell Biol , vol.197 , pp. 857-867
    • Wang, S.1    Kaufman, R.J.2
  • 13
    • 84888419827 scopus 로고    scopus 로고
    • The multifaceted activities of AMPK in tumor progression-why the "one size fits all" definition does not fit at all?
    • Bonini MG, Gantner BN. The multifaceted activities of AMPK in tumor progression-why the "one size fits all" definition does not fit at all? IUBMB Life. 2013; 65:889-896.
    • (2013) IUBMB Life , vol.65 , pp. 889-896
    • Bonini, M.G.1    Gantner, B.N.2
  • 16
    • 84894546213 scopus 로고    scopus 로고
    • The unfolded protein response in glioblastomas: passing the stress test
    • Graner MW. The unfolded protein response in glioblastomas: passing the stress test. CNS Oncology. 2013; 2:1-4.
    • (2013) CNS Oncology , vol.2 , pp. 1-4
    • Graner, M.W.1
  • 17
    • 84878784750 scopus 로고    scopus 로고
    • Comparative Analysis of the Expression Patterns of UPR-Target Genes Caused by UPR-Inducing Compounds
    • Shinjo S, Mizotani Y, Tashiro E, Imoto M. Comparative Analysis of the Expression Patterns of UPR-Target Genes Caused by UPR-Inducing Compounds. Biosci Biotechnol Biochem. 2013; 77:729-735.
    • (2013) Biosci Biotechnol Biochem , vol.77 , pp. 729-735
    • Shinjo, S.1    Mizotani, Y.2    Tashiro, E.3    Imoto, M.4
  • 18
    • 84892511644 scopus 로고    scopus 로고
    • Large-scale gene function analysis with the PANTHER classification system
    • Mi H, Muruganujan A, Casagrande JT, Thomas PD. Large-scale gene function analysis with the PANTHER classification system. Nat Protoc. 2013; 8:1551-1566.
    • (2013) Nat Protoc , vol.8 , pp. 1551-1566
    • Mi, H.1    Muruganujan, A.2    Casagrande, J.T.3    Thomas, P.D.4
  • 20
    • 84872376967 scopus 로고    scopus 로고
    • OASIS/CREB3L1 is induced by endoplasmic reticulum stress in human glioma cell lines and contributes to the unfolded protein response, extracellular matrix production and cell migration
    • Vellanki RN, Zhang L, Volchuk A. OASIS/CREB3L1 is induced by endoplasmic reticulum stress in human glioma cell lines and contributes to the unfolded protein response, extracellular matrix production and cell migration. PLoS One. 2013; 8:e54060.
    • (2013) PLoS One , vol.8
    • Vellanki, R.N.1    Zhang, L.2    Volchuk, A.3
  • 21
    • 84861567265 scopus 로고    scopus 로고
    • Redox signaling loops in the unfolded protein response
    • Higa A, Chevet E. Redox signaling loops in the unfolded protein response. Cell Signal. 2012; 24:1548-1555.
    • (2012) Cell Signal , vol.24 , pp. 1548-1555
    • Higa, A.1    Chevet, E.2
  • 22
    • 84887043259 scopus 로고    scopus 로고
    • Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review
    • Vanderweyde T, Youmans K, Liu-Yesucevitz L, Wolozin B. Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review. Gerontology. 2013; 59:524-533.
    • (2013) Gerontology , vol.59 , pp. 524-533
    • Vanderweyde, T.1    Youmans, K.2    Liu-Yesucevitz, L.3    Wolozin, B.4
  • 23
    • 84929378904 scopus 로고    scopus 로고
    • Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS
    • Momen-Heravi F, Bala S, Kodys K, Szabo G. Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS. Sci Rep. 2015; 5:9991.
    • (2015) Sci Rep , vol.5 , pp. 9991
    • Momen-Heravi, F.1    Bala, S.2    Kodys, K.3    Szabo, G.4
  • 25
    • 17144424622 scopus 로고    scopus 로고
    • Translational control in stress and apoptosis
    • Holcik M, Sonenberg N. Translational control in stress and apoptosis. Nat Rev Mol Cell Biol. 2005; 6:318-327.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 318-327
    • Holcik, M.1    Sonenberg, N.2
  • 26
    • 84900295626 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: its role in disease and novel prospects for therapy
    • Schonthal AH. Endoplasmic reticulum stress: its role in disease and novel prospects for therapy. Scientifica (Cairo). 2012; 2012:857516.
    • (2012) Scientifica (Cairo) , vol.2012
    • Schonthal, A.H.1
  • 28
    • 33745121223 scopus 로고    scopus 로고
    • Therapeutic aspects of chaperones/heat-shock proteins in neuro-oncology
    • Graner MW, Bigner DD. Therapeutic aspects of chaperones/heat-shock proteins in neuro-oncology. Expert Rev Anticancer Ther. 2006; 6:679-695.
    • (2006) Expert Rev Anticancer Ther , vol.6 , pp. 679-695
    • Graner, M.W.1    Bigner, D.D.2
  • 29
    • 84872066036 scopus 로고    scopus 로고
    • Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity
    • Tillo M, Ruhrberg C, Mackenzie F. Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity. Cell Adh Migr. 2012; 6:541-546.
    • (2012) Cell Adh Migr , vol.6 , pp. 541-546
    • Tillo, M.1    Ruhrberg, C.2    Mackenzie, F.3
  • 31
    • 38349049487 scopus 로고    scopus 로고
    • S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response
    • Townsend DM. S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response. Mol Interv. 2007; 7:313-324.
    • (2007) Mol Interv , vol.7 , pp. 313-324
    • Townsend, D.M.1
  • 32
    • 84906712846 scopus 로고    scopus 로고
    • The impact of the endoplasmic reticulum protein-folding environment on cancer development
    • Wang M, Kaufman RJ. The impact of the endoplasmic reticulum protein-folding environment on cancer development. Nat Rev Cancer. 2014; 14:581-597.
    • (2014) Nat Rev Cancer , vol.14 , pp. 581-597
    • Wang, M.1    Kaufman, R.J.2
  • 33
    • 79958235988 scopus 로고    scopus 로고
    • Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas
    • Johnson GG, White MC, Grimaldi M. Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas. Curr Pharm Des. 2011; 17:284-292.
    • (2011) Curr Pharm Des , vol.17 , pp. 284-292
    • Johnson, G.G.1    White, M.C.2    Grimaldi, M.3
  • 34
    • 84922479583 scopus 로고    scopus 로고
    • Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease 3. Orchestrating the unfolded protein response in oncogenesis: an update
    • Manie SN, Lebeau J, Chevet E. Cellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 3. Orchestrating the unfolded protein response in oncogenesis: an update. Am J Physiol Cell Physiol. 2014; 307:C901-907.
    • (2014) Am J Physiol Cell Physiol , vol.307 , pp. C901-C907
    • Manie, S.N.1    Lebeau, J.2    Chevet, E.3
  • 36
    • 55549102665 scopus 로고    scopus 로고
    • A precursorspecific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum
    • Rabu C, Wipf P, Brodsky JL, High S. A precursorspecific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum. J Biol Chem. 2008; 283:27504-27513.
    • (2008) J Biol Chem , vol.283 , pp. 27504-27513
    • Rabu, C.1    Wipf, P.2    Brodsky, J.L.3    High, S.4
  • 37
    • 0842266604 scopus 로고    scopus 로고
    • Oxidative protein folding in eukaryotes: mechanisms and consequences
    • Tu BP, Weissman JS. Oxidative protein folding in eukaryotes: mechanisms and consequences. J Cell Biol. 2004; 164:341-346.
    • (2004) J Cell Biol , vol.164 , pp. 341-346
    • Tu, B.P.1    Weissman, J.S.2
  • 38
    • 33745265207 scopus 로고    scopus 로고
    • Reactive oxygen species: role in the development of cancer and various chronic conditions
    • Waris G, Ahsan H. Reactive oxygen species: role in the development of cancer and various chronic conditions. J Carcinog. 2006; 5:14.
    • (2006) J Carcinog , vol.5 , pp. 14
    • Waris, G.1    Ahsan, H.2
  • 39
    • 77957312329 scopus 로고    scopus 로고
    • From antibodies to adiponectin: role of ERp44 in sizing and timing protein secretion
    • Cortini M, Sitia R. From antibodies to adiponectin: role of ERp44 in sizing and timing protein secretion. Diabetes Obes Metab. 2010; 12:39-47.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 39-47
    • Cortini, M.1    Sitia, R.2
  • 40
    • 84894411492 scopus 로고    scopus 로고
    • Inducing autophagy: a comparative phosphoproteomic study of the cellular response to ammonia and rapamycin
    • Harder LM, Bunkenborg J, Andersen JS. Inducing autophagy: a comparative phosphoproteomic study of the cellular response to ammonia and rapamycin. Autophagy. 2014; 10:339-355.
    • (2014) Autophagy , vol.10 , pp. 339-355
    • Harder, L.M.1    Bunkenborg, J.2    Andersen, J.S.3
  • 44
    • 84859424251 scopus 로고    scopus 로고
    • CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model
    • Kang MJ, Chung J, Ryoo HD. CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model. Nat Cell Biol. 2012; 14:409-415.
    • (2012) Nat Cell Biol , vol.14 , pp. 409-415
    • Kang, M.J.1    Chung, J.2    Ryoo, H.D.3
  • 46
    • 84872054447 scopus 로고    scopus 로고
    • Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis
    • Kropski JA, Lawson WE, Young LR, Blackwell TS. Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. Dis Model Mech. 2013; 6:9-17.
    • (2013) Dis Model Mech , vol.6 , pp. 9-17
    • Kropski, J.A.1    Lawson, W.E.2    Young, L.R.3    Blackwell, T.S.4
  • 47
    • 24644487812 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress response and neurodegeneration
    • Paschen W, Mengesdorf T. Endoplasmic reticulum stress response and neurodegeneration. Cell calcium. 2005; 38(3-4):409-415.
    • (2005) Cell calcium , vol.38 , Issue.3-4 , pp. 409-415
    • Paschen, W.1    Mengesdorf, T.2
  • 49
    • 29244462498 scopus 로고    scopus 로고
    • Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway
    • Cullinan SB, Diehl JA. Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. Int J Biochem Cell Biol. 2006; 38:317-332.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 317-332
    • Cullinan, S.B.1    Diehl, J.A.2
  • 55
    • 84883014367 scopus 로고    scopus 로고
    • Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts
    • Leclerc GM, Leclerc GJ, Kuznetsov JN, DeSalvo J, Barredo JC. Metformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts. PLoS One. 2013; 8:e74420.
    • (2013) PLoS One , vol.8
    • Leclerc, G.M.1    Leclerc, G.J.2    Kuznetsov, J.N.3    DeSalvo, J.4    Barredo, J.C.5
  • 56
    • 79955755022 scopus 로고    scopus 로고
    • AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia
    • Kuznetsov JN, Leclerc GJ, Leclerc GM, Barredo JC. AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in acute lymphoblastic leukemia. Mol Cancer Ther. 2011; 10:437-447.
    • (2011) Mol Cancer Ther , vol.10 , pp. 437-447
    • Kuznetsov, J.N.1    Leclerc, G.J.2    Leclerc, G.M.3    Barredo, J.C.4
  • 57
    • 84908317120 scopus 로고    scopus 로고
    • Metabolic respiration induces AMPK-and Ire1p-dependent activation of the p38-Type HOG MAPK pathway
    • Adhikari H, Cullen PJ. Metabolic respiration induces AMPK-and Ire1p-dependent activation of the p38-Type HOG MAPK pathway. PLoS Genet. 2014; 10:e1004734.
    • (2014) PLoS Genet , vol.10
    • Adhikari, H.1    Cullen, P.J.2
  • 58
    • 84922927024 scopus 로고    scopus 로고
    • Depletion of the cereblon gene activates the unfolded protein response and protects cells from ER stress-induced cell death
    • Lee KM, Yang SJ, Park S, Choi YD, Shin HK, Pak JH, Park CS, Kim I. Depletion of the cereblon gene activates the unfolded protein response and protects cells from ER stress-induced cell death. Biochem Biophys Res Commun. 2015; 458:34-39.
    • (2015) Biochem Biophys Res Commun , vol.458 , pp. 34-39
    • Lee, K.M.1    Yang, S.J.2    Park, S.3    Choi, Y.D.4    Shin, H.K.5    Pak, J.H.6    Park, C.S.7    Kim, I.8
  • 60
    • 84949116627 scopus 로고    scopus 로고
    • Heat shock protein 27 phosphorylation state is associated with cancer progression
    • Katsogiannou M, Andrieu C, Rocchi P. Heat shock protein 27 phosphorylation state is associated with cancer progression. Front Genet. 2014; 5:346.
    • (2014) Front Genet , vol.5 , pp. 346
    • Katsogiannou, M.1    Andrieu, C.2    Rocchi, P.3
  • 63
    • 84862524611 scopus 로고    scopus 로고
    • Role of PRAS40 in Akt and mTOR signaling in health and disease
    • Wiza C, Nascimento EB, Ouwens DM. Role of PRAS40 in Akt and mTOR signaling in health and disease. Am J Physiol Endocrinol Metab. 2012; 302:E1453-1460.
    • (2012) Am J Physiol Endocrinol Metab , vol.302 , pp. E1453-E1460
    • Wiza, C.1    Nascimento, E.B.2    Ouwens, D.M.3
  • 64
    • 79959230673 scopus 로고    scopus 로고
    • ER stress induces anabolic resistance in muscle cells through PKB-induced blockade of mTORC1
    • Deldicque L, Bertrand L, Patton A, Francaux M, Baar K. ER stress induces anabolic resistance in muscle cells through PKB-induced blockade of mTORC1. PLoS One. 2011; 6:e20993.
    • (2011) PLoS One , vol.6
    • Deldicque, L.1    Bertrand, L.2    Patton, A.3    Francaux, M.4    Baar, K.5
  • 66
    • 34250312427 scopus 로고    scopus 로고
    • TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response
    • Nowis D, McConnell EJ, Dierlam L, Palamarchuk A, Lass A, Wojcik C. TNF potentiates anticancer activity of bortezomib (Velcade) through reduced expression of proteasome subunits and dysregulation of unfolded protein response. Int J Cancer. 2007; 121:431-441.
    • (2007) Int J Cancer , vol.121 , pp. 431-441
    • Nowis, D.1    McConnell, E.J.2    Dierlam, L.3    Palamarchuk, A.4    Lass, A.5    Wojcik, C.6
  • 67
    • 4644354440 scopus 로고    scopus 로고
    • Control of tumor suppressor p53 function by endoplasmic reticulum stress
    • Qu L, Koromilas AE. Control of tumor suppressor p53 function by endoplasmic reticulum stress. Cell Cycle. 2004; 3:567-570.
    • (2004) Cell Cycle , vol.3 , pp. 567-570
    • Qu, L.1    Koromilas, A.E.2
  • 68
    • 84891855570 scopus 로고    scopus 로고
    • Mitogenactivated protein kinase-activated protein kinase 2 in neuroinflammation, heat shock protein 27 phosphorylation, and cell cycle: role and targeting
    • Gurgis FM, Ziaziaris W, Munoz L. Mitogenactivated protein kinase-activated protein kinase 2 in neuroinflammation, heat shock protein 27 phosphorylation, and cell cycle: role and targeting. Mol Pharmacol. 2014; 85:345-356.
    • (2014) Mol Pharmacol , vol.85 , pp. 345-356
    • Gurgis, F.M.1    Ziaziaris, W.2    Munoz, L.3
  • 69
    • 76749088358 scopus 로고    scopus 로고
    • Pathological roles of MAPK signaling pathways in human diseases
    • Kim EK, Choi EJ. Pathological roles of MAPK signaling pathways in human diseases. Biochim Biophys Acta. 2010; 1802:396-405.
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 396-405
    • Kim, E.K.1    Choi, E.J.2
  • 70
    • 22944479314 scopus 로고    scopus 로고
    • JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3
    • Sunayama J, Tsuruta F, Masuyama N, Gotoh Y. JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. J Cell Biol. 2005; 170:295-304.
    • (2005) J Cell Biol , vol.170 , pp. 295-304
    • Sunayama, J.1    Tsuruta, F.2    Masuyama, N.3    Gotoh, Y.4
  • 71
    • 77957772337 scopus 로고    scopus 로고
    • Differences in endoplasmic reticulum stress signalling kinetics determine cell survival outcome through activation of MKP-1
    • Li B, Yi P, Zhang B, Xu C, Liu Q, Pi Z, Xu X, Chevet E, Liu J. Differences in endoplasmic reticulum stress signalling kinetics determine cell survival outcome through activation of MKP-1. Cell Signal. 2011; 23:35-45.
    • (2011) Cell Signal , vol.23 , pp. 35-45
    • Li, B.1    Yi, P.2    Zhang, B.3    Xu, C.4    Liu, Q.5    Pi, Z.6    Xu, X.7    Chevet, E.8    Liu, J.9
  • 72
    • 0036020543 scopus 로고    scopus 로고
    • Modulating poly (ADP-ribose) polymerase activity: potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress
    • Decker P, Muller S. Modulating poly (ADP-ribose) polymerase activity: potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress. Curr Pharm Biotechnol. 2002; 3:275-283.
    • (2002) Curr Pharm Biotechnol , vol.3 , pp. 275-283
    • Decker, P.1    Muller, S.2
  • 73
    • 84858169363 scopus 로고    scopus 로고
    • PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration
    • Chaitanya GV, Steven AJ, Babu PP. PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration. Cell Commun Signal. 2010; 8:31.
    • (2010) Cell Commun Signal , vol.8 , pp. 31
    • Chaitanya, G.V.1    Steven, A.J.2    Babu, P.P.3
  • 75
    • 33744962234 scopus 로고    scopus 로고
    • Activation and crosstalk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78
    • Misra UK, Deedwania R, Pizzo SV. Activation and crosstalk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78. J Biol Chem. 2006; 281:13694-13707.
    • (2006) J Biol Chem , vol.281 , pp. 13694-13707
    • Misra, U.K.1    Deedwania, R.2    Pizzo, S.V.3
  • 76
    • 84884818386 scopus 로고    scopus 로고
    • Hypoxia-triggered m-calpain activation evokes endoplasmic reticulum stress and neuropathogenesis in a transgenic mouse model of Alzheimer's disease
    • Wang CY, Xie JW, Wang T, Xu Y, Cai JH, Wang X, Zhao BL, An L, Wang ZY. Hypoxia-triggered m-calpain activation evokes endoplasmic reticulum stress and neuropathogenesis in a transgenic mouse model of Alzheimer's disease. CNS Neurosci Ther. 2013; 19:820-833.
    • (2013) CNS Neurosci Ther , vol.19 , pp. 820-833
    • Wang, C.Y.1    Xie, J.W.2    Wang, T.3    Xu, Y.4    Cai, J.H.5    Wang, X.6    Zhao, B.L.7    An, L.8    Wang, Z.Y.9
  • 77
    • 84933042431 scopus 로고    scopus 로고
    • Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3alpha/beta regulate foam cell formation
    • McAlpine CS, Werstuck GH. Protein kinase R-like endoplasmic reticulum kinase and glycogen synthase kinase-3alpha/beta regulate foam cell formation. J Lipid Res. 2014; 55:2320-2333.
    • (2014) J Lipid Res , vol.55 , pp. 2320-2333
    • McAlpine, C.S.1    Werstuck, G.H.2
  • 78
    • 34247116441 scopus 로고    scopus 로고
    • Physiological roles of PKB/Akt isoforms in development and disease
    • Dummler B, Hemmings BA. Physiological roles of PKB/Akt isoforms in development and disease. Biochem Soc Trans. 2007; 35:231-235.
    • (2007) Biochem Soc Trans , vol.35 , pp. 231-235
    • Dummler, B.1    Hemmings, B.A.2
  • 79
    • 10344253840 scopus 로고    scopus 로고
    • Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    • Hu P, Han Z, Couvillon AD, Exton JH. Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. J Biol Chem. 2004; 279:49420-49429.
    • (2004) J Biol Chem , vol.279 , pp. 49420-49429
    • Hu, P.1    Han, Z.2    Couvillon, A.D.3    Exton, J.H.4
  • 80
    • 67649438633 scopus 로고    scopus 로고
    • Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells
    • Dai R, Chen R, Li H. Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells. Int J Oncol. 2009; 34:1749-1757.
    • (2009) Int J Oncol , vol.34 , pp. 1749-1757
    • Dai, R.1    Chen, R.2    Li, H.3
  • 82
    • 67649401776 scopus 로고    scopus 로고
    • Exposure of human leukemia NB4 cells to increasing concentrations of selenite switches the signaling from prosurvival to pro-apoptosis
    • Guan L, Han B, Li J, Li Z, Huang F, Yang Y, Xu C. Exposure of human leukemia NB4 cells to increasing concentrations of selenite switches the signaling from prosurvival to pro-apoptosis. Ann Hematol. 2009; 88:733-742.
    • (2009) Ann Hematol , vol.88 , pp. 733-742
    • Guan, L.1    Han, B.2    Li, J.3    Li, Z.4    Huang, F.5    Yang, Y.6    Xu, C.7
  • 84
    • 84879005716 scopus 로고    scopus 로고
    • The role of Stat3 in glioblastoma multiforme
    • Luwor RB, Stylli SS, Kaye AH. The role of Stat3 in glioblastoma multiforme. J Clin Neurosci. 2013; 20:907-911.
    • (2013) J Clin Neurosci , vol.20 , pp. 907-911
    • Luwor, R.B.1    Stylli, S.S.2    Kaye, A.H.3
  • 88
    • 84875143788 scopus 로고    scopus 로고
    • Targeting endoplasmic reticulum stress in metabolic disease
    • Cao SS, Kaufman RJ. Targeting endoplasmic reticulum stress in metabolic disease. Expert Opin Ther Targets. 2013; 17:437-448.
    • (2013) Expert Opin Ther Targets , vol.17 , pp. 437-448
    • Cao, S.S.1    Kaufman, R.J.2
  • 89
    • 84883387793 scopus 로고    scopus 로고
    • Targeting the unfolded protein response in disease
    • Hetz C, Chevet E, Harding HP. Targeting the unfolded protein response in disease. Nat Rev Drug Discov. 2013; 12:703-719.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 703-719
    • Hetz, C.1    Chevet, E.2    Harding, H.P.3
  • 91
    • 84942990748 scopus 로고    scopus 로고
    • A phase II trial of tamoxifen and bortezomib in patients with recurrent malignant gliomas
    • Odia Y, Kreisl TN, Aregawi D, Innis EK, Fine HA. A phase II trial of tamoxifen and bortezomib in patients with recurrent malignant gliomas. J Neurooncol. 2015; 125:191-195.
    • (2015) J Neurooncol , vol.125 , pp. 191-195
    • Odia, Y.1    Kreisl, T.N.2    Aregawi, D.3    Innis, E.K.4    Fine, H.A.5
  • 92
    • 84864773480 scopus 로고    scopus 로고
    • DangER: protein ovERload. Targeting protein degradation to treat myeloma
    • Aronson LI, Davies FE. DangER: protein ovERload. Targeting protein degradation to treat myeloma. Haematologica. 2012; 97:1119-1130.
    • (2012) Haematologica , vol.97 , pp. 1119-1130
    • Aronson, L.I.1    Davies, F.E.2
  • 93
    • 84889250555 scopus 로고    scopus 로고
    • Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis
    • Bota DA, Alexandru D, Keir ST, Bigner D, Vredenburgh J, Friedman HS. Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis. J Neurosurg. 2013; 119:1415-1423.
    • (2013) J Neurosurg , vol.119 , pp. 1415-1423
    • Bota, D.A.1    Alexandru, D.2    Keir, S.T.3    Bigner, D.4    Vredenburgh, J.5    Friedman, H.S.6
  • 95
    • 84861551579 scopus 로고    scopus 로고
    • ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Aktdependent context in malignant human glioma cell lines
    • Premkumar DR, Jane EP, DiDomenico JD, Vukmer NA, Agostino NR, Pollack IF. ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Aktdependent context in malignant human glioma cell lines. J Pharmacol Exp Ther. 2012; 341:859-872.
    • (2012) J Pharmacol Exp Ther , vol.341 , pp. 859-872
    • Premkumar, D.R.1    Jane, E.P.2    DiDomenico, J.D.3    Vukmer, N.A.4    Agostino, N.R.5    Pollack, I.F.6
  • 98
    • 84908036925 scopus 로고    scopus 로고
    • Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro
    • Smyth TJ, Redzic JS, Graner MW, Anchordoquy TJ. Examination of the specificity of tumor cell derived exosomes with tumor cells in vitro. Biochim Biophys Acta. 2014; 1838:2954-2965.
    • (2014) Biochim Biophys Acta , vol.1838 , pp. 2954-2965
    • Smyth, T.J.1    Redzic, J.S.2    Graner, M.W.3    Anchordoquy, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.