OASIS/CREB3L1 Is Induced by Endoplasmic Reticulum Stress in Human Glioma Cell Lines and Contributes to the Unfolded Protein Response, Extracellular Matrix Production and Cell Migration

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Vellanki, Ravi N ^a,c   Zhang, Liling ^a   Volchuk, Allen ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN CREB3L1; PROTEIN OASIS; PROTEOCHONDROITIN SULFATE; SCLEROPROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL MIGRATION; CELL STRAIN 373; CELL STRAIN A172; CELL STRAIN U87; CELL STRUCTURE; COL1A1 GENE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; EXTRACELLULAR MATRIX; FLUORESCENCE MICROSCOPY; GENE; GLIOMA CELL; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PLASMID; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

CELL LINE, TUMOR; CELL MOVEMENT; CHONDROITIN SULFATES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENDOPLASMIC RETICULUM STRESS; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; GLYCOSYLATION; HUMANS; NERVE TISSUE PROTEINS; PROTEOGLYCANS; RNA, MESSENGER; UNFOLDED PROTEIN RESPONSE;

EID: 84872376967     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054060     Document Type: Article

References (40)

1. Ron D, Walter P, (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8: 519-529.
2. Kim I, Xu W, Reed JC, (2008) Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 7: 1013-1030.
3. Eizirik DL, Cardozo AK, Cnop M, (2008) The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev 29: 42-61.
4. Hotamisligil G, (2010) Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease. Cell 140: 900-917.
5. Lindholm D, Wootz H, Korhonen L, (2006) ER stress and neurodegenerative diseases. Cell Death Differen 13: 385-392.
6. Yang W, Paschen W, (2009) The endoplasmic reticulum and neurological diseases. Experimental Neurology 219: 376-381.
7. Zhang K, Kaufman RJ, (2006) The unfolded protein response: A stress signaling pathway critical for health and disease. Neurology 66: S102-S109.
8. Lai E, Teodoro T, Volchuk A, (2007) Endoplasmic Reticulum Stress: Signaling the Unfolded Protein Response. Physiology 22: 193-201.
9. Ron D, Walter P, (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8: 519-529.
10. Bailey D, O' Hare P, (2007) Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response. Antioxid Redox Signal 9: 2305-2321.
11. Kohno K, (2007) How transmembrane proteins sense endoplasmic reticulum stress. Antioxid Redox Signal 9: 2295-2303.
12. Fox RM, Hanlon CD, Andrew DJ, (2010) The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J Cell Biol 191: 479-492.
13. Honma Y, Kanazawa K, Mori T, Tanno Y, Tojo M, et al. (1999) Identification of a novel gene, OASIS, which encodes for a putative CREB/ATF family transcription factor in the long-term cultured astrocytes and gliotic tissue. Brain Res Mol Brain Res 69: 93-103.
14. Omori Y, Imai J, Suzuki Y, Watanabe S, Tanigami A, et al. (2002) OASIS is a transcriptional activator of CREB/ATF family with a transmembrane domain. Biochem Biophys Res Commun 293: 470-477.
15. Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, et al. (2003) Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development. Acta Embryol 206: 373-380.
16. Murakami T, Saito A, Hino S, Kondo S, Kanemoto S, et al. (2009) Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation. Nat Cell Biol 11: 1205-1211.
17. Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, et al. (2011) Endoplasmic reticulum stress response mediated by the PERK-eIF2a-ATF4 pathway is involved in osteoblast differentiation induced by BMP2. J Biol Chem 286: 4809-4818.
18. Vellanki RN, Zhang L, Guney MA, Rocheleau JV, Gannon M, et al. (2010) OASIS/CREB3l1 induces expression of genes involved in extracellular matrix production but not classical endoplasmic reticulum stress response genes in pancreatic beta-cells. Endocrinology 151: 4146-4157.
19. Ogaki S, Harada S, Shiraki N, Kume K, Kume S, (2011) An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. BMC Dev Biol 11: 13.
20. Kondo S, Murakami T, Tatsumi K, Ogata M, Kanemoto S, et al. (2005) OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes. Nat Cell Biol 7: 186-194.
21. Murakami T, Kondo S, Ogata M, Kanemoto S, Saito A, et al. (2006) Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress. J Neurochem 96: 1090-1100.
22. Wouters BG, Koritzinsky M, (2008) Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer 8: 851-864.
23. Johnson GG, White MC, Grimaldi M, (2011) Stressed to death: targeting endoplasmic reticulum stress response induced apoptosis in gliomas. Curr Pharm Des 17: 284-292.
24. Barkan D, Green JE, Chambers AF, (2010) Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth. Eur J Cancer 46: 1181-1188.
25. Krakstad C, Chekenya M, (2010) Survival signaling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics. Mol Cancer 9: 135.
26. Ulrich TA, de Juan Pardo EM, Kumar S, (2009) The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res 69: 4167-4174.
27. Gladson CL, (1999) The extracellular matrix of gliomas: modulation of cell function. J Neuropath Exp Neur 58: 1029-1040.
28. Brismar T, (1995) Physiology of transformed glial cells. Glia 15: 231-243.
29. Beckman G, Beckman L, Ponten J, Westermark B, (1971) G-6-PD and PGM phenotypes of 16 continuous human tumor cell lines. Evidence againts cross-contamination and contamination by HeLa cells. Hum Hered 21: 238-241.
30. Clark MJ, Homer N, O'Connor BD, Chen Z, Eskin A, et al. (2010) U87MG decoded: the genomic sequence of a cytogenetically aberrant human cancer cell line. PLoS Genet 6: e1000832.
31. Giard DJ, Aaronson SA, Todaro GJ, Arnstein P, Kersey JH, et al. (1973) In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst 51: 1417-1423.
32. Zhang L, Lai E, Teodoro T, Volchuk A, (2009) GRP78, but not protein-disulfide isomerase, partially reverses hyperglycemia-induced inhibition of insulin synthesis and secretion in pancreatic beta-cells. J Biol Chem 284: 5289-5298.
33. Natori T, Nagai K, (2008) Endoplasmic reticulum stress upregulates the chondroitin sulfate level which thus prevents neurite extension in C6 glioma cells and primary cultured astrocytes. Cell Mol Neurobiol 28: 857-866.
34. Lander C, Kind P, Maleski M, Hockfield S, (1997) A family of activity-dependent neuronal cell-surface chondroitin sulfate proteoglycans in cat visual cortex. J Neurosci 17: 1928-1939.
35. Hong M, Luo S, Baumeister P, Huang JM, Gogia RK, et al. (2004) Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response. J Biol Chem 279: 11354-11363.
36. Saito A, Hino S-I, Murakami T, Kondo S, Imaizumi K, (2007) A novel ER stress transducer, OASIS, expressed in astrocytes. Antioxid Redox Signal 9: 563-571.
37. Correa TCS, Massaro RR, Brohem CA, Taboga SR, Lamers ML, et al. (2010) RECK-mediated inhibition of glioma migration and invasion. J Cell Biochem 110: 52-61.
38. Rorth P, (2009) Collective cell migration. Annu Rev Cell Dev Biol 25: 407-429.
39. Wang D, Anderson JC, Gladson CL, (2005) The role of the extracellular matrix in angiogenesis in malignant glioma tumors. Brain Pathol 15: 318-326.
40. Network TCGAR, (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068.