-
1
-
-
84887621906
-
Paneth cells as a site of origin for intestinal inflammation
-
Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Bock J, Martinez- Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS. Paneth cells as a site of origin for intestinal inflammation. Nature 503: 272-276, 2014.
-
(2014)
Nature
, vol.503
, pp. 272-276
-
-
Adolph, T.E.1
Tomczak, M.F.2
Niederreiter, L.3
Ko, H.J.4
Bock, J.5
Martinez-Naves, E.6
Glickman, J.N.7
Tschurtschenthaler, M.8
Hartwig, J.9
Hosomi, S.10
Flak, M.B.11
Cusick, J.L.12
Kohno, K.13
Iwawaki, T.14
Billmann-Born, S.15
Raine, T.16
Bharti, R.17
Lucius, R.18
Kweon, M.N.19
Marciniak, S.J.20
Choi, A.21
Hagen, S.J.22
Schreiber, S.23
Rosenstiel, P.24
Kaser, A.25
Blumberg, R.S.26
more..
-
2
-
-
29344457845
-
Transformationassociated gene regulation by ATF6alpha during hepatocarcinogenesis
-
Arai M, Kondoh N, Imazeki N, Hada A, Hatsuse K, Kimura F, Matsubara O, Mori K, Wakatsuki T, Yamamoto M. Transformationassociated gene regulation by ATF6alpha during hepatocarcinogenesis. FEBS Lett 580: 184-190, 2006.
-
(2006)
FEBS Lett
, vol.580
, pp. 184-190
-
-
Arai, M.1
Kondoh, N.2
Imazeki, N.3
Hada, A.4
Hatsuse, K.5
Kimura, F.6
Matsubara, O.7
Mori, K.8
Wakatsuki, T.9
Yamamoto, M.10
-
3
-
-
77957288028
-
Inositolrequiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma
-
Auf G, Jabouille A, Guerit S, Pineau R, Delugin M, Bouchecareilh M, Magnin N, Favereaux A, Maitre M, Gaiser T, von Deimling A, Czabanka M, Vajkoczy P, Chevet E, Bikfalvi A, Moenner M. Inositolrequiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma. Proc Natl Acad Sci USA 107: 15553-15558, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15553-15558
-
-
Auf, G.1
Jabouille, A.2
Guerit, S.3
Pineau, R.4
Delugin, M.5
Bouchecareilh, M.6
Magnin, N.7
Favereaux, A.8
Maitre, M.9
Gaiser, T.10
von Deimling, A.11
Czabanka, M.12
Vajkoczy, P.13
Chevet, E.14
Bikfalvi, A.15
Moenner, M.16
-
4
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
Balch WE, Morimoto RI, Dillin A, Kelly JW. Adapting proteostasis for disease intervention. Science 319: 916-919, 2008.
-
(2008)
Science
, vol.319
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
5
-
-
33845465578
-
Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress
-
Blais JD, Addison CL, Edge R, Falls T, Zhao H, Wary K, Koumenis C, Harding HP, Ron D, Holcik M, Bell JC. Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress. Mol Cell Biol 26: 9517-9532, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9517-9532
-
-
Blais, J.D.1
Addison, C.L.2
Edge, R.3
Falls, T.4
Zhao, H.5
Wary, K.6
Koumenis, C.7
Harding, H.P.8
Ron, D.9
Holcik, M.10
Bell, J.C.11
-
6
-
-
84908018421
-
Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 2. Protein misfolding and ER stress
-
(June 18)
-
Chambers JE, Marciniak SJ. Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 2. Protein misfolding and ER stress. Am J Physiol Cell Physiol (June 18, 2014). doi:10.1152/ ajpcell.00183.2014.
-
(2014)
Am J Physiol Cell Physiol
-
-
Chambers, J.E.1
Marciniak, S.J.2
-
7
-
-
84897541350
-
XBP1 promotes triple-negative breast cancer by controlling the HIF1alpha pathway
-
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, Song M, Tan C, Landis MD, Ferrari M, Shin SJ, Brown M, Chang JC, Liu XS, Glimcher LH. XBP1 promotes triple-negative breast cancer by controlling the HIF1alpha pathway. Nature 508: 103-107, 2014.
-
(2014)
Nature
, vol.508
, pp. 103-107
-
-
Chen, X.1
Iliopoulos, D.2
Zhang, Q.3
Tang, Q.4
Greenblatt, M.B.5
Hatziapostolou, M.6
Lim, E.7
Tam, W.L.8
Ni, M.9
Chen, Y.10
Mai, J.11
Shen, H.12
Hu, D.Z.13
Adoro, S.14
Hu, B.15
Song, M.16
Tan, C.17
Landis, M.D.18
Ferrari, M.19
Shin, S.J.20
Brown, M.21
Chang, J.C.22
Liu, X.S.23
Glimcher, L.H.24
more..
-
8
-
-
72649087136
-
Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver
-
Cretenet G, Le Clech M, Gachon F. Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver. Cell Metab 11: 47-57, 2010.
-
(2010)
Cell Metab
, vol.11
, pp. 47-57
-
-
Cretenet, G.1
Le Clech, M.2
Gachon, F.3
-
9
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 7: 11-20, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 11-20
-
-
DeBerardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
10
-
-
84899940537
-
Addicted to secrete - novel concepts and targets in cancer therapy
-
Dejeans N, Manie S, Hetz C, Bard F, Hupp T, Agostinis P, Samali A, Chevet E. Addicted to secrete - novel concepts and targets in cancer therapy. Trends Mol Med 20: 242-250, 2014.
-
(2014)
Trends Mol Med
, vol.20
, pp. 242-250
-
-
Dejeans, N.1
Manie, S.2
Hetz, C.3
Bard, F.4
Hupp, T.5
Agostinis, P.6
Samali, A.7
Chevet, E.8
-
11
-
-
84872173393
-
Autocrine control of glioma cells adhesion and migration through IRE1alpha-mediated cleavage of SPARC mRNA
-
Dejeans N, Pluquet O, Lhomond S, Grise F, Bouchecareilh M, Juin A, Meynard-Cadars M, Bidaud-Meynard A, Gentil C, Moreau V, Saltel F, Chevet E. Autocrine control of glioma cells adhesion and migration through IRE1alpha-mediated cleavage of SPARC mRNA. J Cell Sci 125: 4278-4287, 2012.
-
(2012)
J Cell Sci
, vol.125
, pp. 4278-4287
-
-
Dejeans, N.1
Pluquet, O.2
Lhomond, S.3
Grise, F.4
Bouchecareilh, M.5
Juin, A.6
Meynard-Cadars, M.7
Bidaud-Meynard, A.8
Gentil, C.9
Moreau, V.10
Saltel, F.11
Chevet, E.12
-
12
-
-
33749184798
-
Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway
-
Denoyelle C, Abou-Rjaily G, Bezrookove V, Verhaegen M, Johnson TM, Fullen DR, Pointer JN, Gruber SB, Su LD, Nikiforov MA, Kaufman RJ, Bastian BC, Soengas MS. Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway. Nat Cell Biol 8: 1053-1063, 2006.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1053-1063
-
-
Denoyelle, C.1
Abou-Rjaily, G.2
Bezrookove, V.3
Verhaegen, M.4
Johnson, T.M.5
Fullen, D.R.6
Pointer, J.N.7
Gruber, S.B.8
Su, L.D.9
Nikiforov, M.A.10
Kaufman, R.J.11
Bastian, B.C.12
Soengas, M.S.13
-
13
-
-
84896351253
-
Hexosamine pathway metabolites enhance protein quality control and prolong life
-
Denzel MS, Storm NJ, Gutschmidt A, Baddi R, Hinze Y, Jarosch E, Sommer T, Hoppe T, Antebi A. Hexosamine pathway metabolites enhance protein quality control and prolong life. Cell 156: 1167-1178, 2014.
-
(2014)
Cell
, vol.156
, pp. 1167-1178
-
-
Denzel, M.S.1
Storm, N.J.2
Gutschmidt, A.3
Baddi, R.4
Hinze, Y.5
Jarosch, E.6
Sommer, T.7
Hoppe, T.8
Antebi, A.9
-
14
-
-
34547114745
-
IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo
-
Drogat B, Auguste P, Nguyen DT, Bouchecareilh M, Pineau R, Nalbantoglu J, Kaufman RJ, Chevet E, Bikfalvi A, Moenner M. IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo. Cancer Res 67: 6700-6707, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 6700-6707
-
-
Drogat, B.1
Auguste, P.2
Nguyen, D.T.3
Bouchecareilh, M.4
Pineau, R.5
Nalbantoglu, J.6
Kaufman, R.J.7
Chevet, E.8
Bikfalvi, A.9
Moenner, M.10
-
15
-
-
84907539353
-
Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 1. An overview
-
(August 20)
-
Dufey E, Sepulveda D, Rojas-Rivera D, Hetz C. Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 1. An overview. Am J Physiol Cell Physiol (August 20, 2014). doi:10.1152/ ajpcell.00058.2014.
-
(2014)
Am J Physiol Cell Physiol
-
-
Dufey, E.1
Sepulveda, D.2
Rojas-Rivera, D.3
Hetz, C.4
-
16
-
-
84905392984
-
Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and celecoxib
-
Edagawa M, Kawauchi J, Hirata M, Goshima H, Inoue M, Okamoto T, Murakami A, Maehara Y, Kitajima S. Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-regulation of death receptor 5 (DR5) by zerumbone and celecoxib. J Biol Chem 289: 21544-21561, 2014.
-
(2014)
J Biol Chem
, vol.289
, pp. 21544-21561
-
-
Edagawa, M.1
Kawauchi, J.2
Hirata, M.3
Goshima, H.4
Inoue, M.5
Okamoto, T.6
Murakami, A.7
Maehara, Y.8
Kitajima, S.9
-
17
-
-
84904053401
-
Epithelialto- mesenchymal transition activates PERK-eIF2alpha and sensitizes cells to endoplasmic reticulum stress
-
Feng YX, Sokol ES, Del Vecchio CA, Sanduja S, Claessen JH, Proia TA, Jin DX, Reinhardt F, Ploegh HL, Wang Q, Gupta PB. Epithelialto- mesenchymal transition activates PERK-eIF2alpha and sensitizes cells to endoplasmic reticulum stress. Cancer Discov 4: 702-715, 2014.
-
(2014)
Cancer Discov
, vol.4
, pp. 702-715
-
-
Feng, Y.X.1
Sokol, E.S.2
Del Vecchio, C.A.3
Sanduja, S.4
Claessen, J.H.5
Proia, T.A.6
Jin, D.X.7
Reinhardt, F.8
Ploegh, H.L.9
Wang, Q.10
Gupta, P.B.11
-
18
-
-
84901946068
-
O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway
-
Ferrer CM, Lynch TP, Sodi VL, Falcone JN, Schwab LP, Peacock DL, Vocadlo DJ, Seagroves TN, Reginato MJ. O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway. Mol Cell 54: 820-831, 2014.
-
(2014)
Mol Cell
, vol.54
, pp. 820-831
-
-
Ferrer, C.M.1
Lynch, T.P.2
Sodi, V.L.3
Falcone, J.N.4
Schwab, L.P.5
Peacock, D.L.6
Vocadlo, D.J.7
Seagroves, T.N.8
Reginato, M.J.9
-
19
-
-
84880040665
-
P97/CDC-48: Proteostasis control in tumor cell biology
-
Fessart D, Marza E, Taouji S, Delom F, Chevet E. P97/CDC-48: proteostasis control in tumor cell biology. Cancer Lett 337: 26-34, 2013.
-
(2013)
Cancer Lett
, vol.337
, pp. 26-34
-
-
Fessart, D.1
Marza, E.2
Taouji, S.3
Delom, F.4
Chevet, E.5
-
20
-
-
84905492694
-
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress
-
Ghosh R, Wang L, Wang ES, Perera BG, Igbaria A, Morita S, Prado K, Thamsen M, Caswell D, Macias H, Weiberth KF, Gliedt MJ, Alavi MV, Hari SB, Mitra AK, Bhhatarai B, Schurer SC, Snapp EL, Gould DB, German MS, Backes BJ, Maly DJ, Oakes SA, Papa FR. Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress. Cell 158: 534-548, 2014.
-
(2014)
Cell
, vol.158
, pp. 534-548
-
-
Ghosh, R.1
Wang, L.2
Wang, E.S.3
Perera, B.G.4
Igbaria, A.5
Morita, S.6
Prado, K.7
Thamsen, M.8
Caswell, D.9
Macias, H.10
Weiberth, K.F.11
Gliedt, M.J.12
Alavi, M.V.13
Hari, S.B.14
Mitra, A.K.15
Bhhatarai, B.16
Schurer, S.C.17
Snapp, E.L.18
Gould, D.B.19
German, M.S.20
Backes, B.J.21
Maly, D.J.22
Oakes, S.A.23
Papa, F.R.24
more..
-
21
-
-
33947101019
-
Patterns of somatic mutation in human cancer genomes
-
Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR. Patterns of somatic mutation in human cancer genomes. Nature 446: 153-158, 2007.
-
(2007)
Nature
, vol.446
, pp. 153-158
-
-
Greenman, C.1
Stephens, P.2
Smith, R.3
Dalgliesh, G.L.4
Hunter, C.5
Bignell, G.6
Davies, H.7
Teague, J.8
Butler, A.9
Stevens, C.10
Edkins, S.11
O'Meara, S.12
Vastrik, I.13
Schmidt, E.E.14
Avis, T.15
Barthorpe, S.16
Bhamra, G.17
Buck, G.18
Choudhury, B.19
Clements, J.20
Cole, J.21
Dicks, E.22
Forbes, S.23
Gray, K.24
Halliday, K.25
Harrison, R.26
Hills, K.27
Hinton, J.28
Jenkinson, A.29
Jones, D.30
Menzies, A.31
Mironenko, T.32
Perry, J.33
Raine, K.34
Richardson, D.35
Shepherd, R.36
Small, A.37
Tofts, C.38
Varian, J.39
Webb, T.40
West, S.41
Widaa, S.42
Yates, A.43
Cahill, D.P.44
Louis, D.N.45
Goldstraw, P.46
Nicholson, A.G.47
Brasseur, F.48
Looijenga, L.49
Weber, B.L.50
Chiew, Y.E.51
DeFazio, A.52
Greaves, M.F.53
Green, A.R.54
Campbell, P.55
Birney, E.56
Easton, D.F.57
Chenevix-Trench, G.58
Tan, M.H.59
Khoo, S.K.60
Teh, B.T.61
Yuen, S.T.62
Leung, S.Y.63
Wooster, R.64
Futreal, P.A.65
Stratton, M.R.66
more..
-
22
-
-
84861625981
-
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
-
Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB, Calderaro J, Bioulac-Sage P, Letexier M, Degos F, Clement B, Balabaud C, Chevet E, Laurent A, Couchy G, Letouze E, Calvo F, Zucman-Rossi J. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 44: 694-698, 2012.
-
(2012)
Nat Genet
, vol.44
, pp. 694-698
-
-
Guichard, C.1
Amaddeo, G.2
Imbeaud, S.3
Ladeiro, Y.4
Pelletier, L.5
Maad, I.B.6
Calderaro, J.7
Bioulac-Sage, P.8
Letexier, M.9
Degos, F.10
Clement, B.11
Balabaud, C.12
Chevet, E.13
Laurent, A.14
Couchy, G.15
Letouze, E.16
Calvo, F.17
Zucman-Rossi, J.18
-
23
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 144: 646-674, 2011.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
24
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274, 1999.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
25
-
-
84870546460
-
ER stress-mediated autophagy promotes Mycdependent transformation and tumor growth
-
Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Tikhonenko AT, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C. ER stress-mediated autophagy promotes Mycdependent transformation and tumor growth. J Clin Invest 122: 4621-4634, 2012.
-
(2012)
J Clin Invest
, vol.122
, pp. 4621-4634
-
-
Hart, L.S.1
Cunningham, J.T.2
Datta, T.3
Dey, S.4
Tameire, F.5
Lehman, S.L.6
Qiu, B.7
Zhang, H.8
Cerniglia, G.9
Bi, M.10
Li, Y.11
Gao, Y.12
Liu, H.13
Li, C.14
Maity, A.15
Tikhonenko, A.T.16
Perl, A.E.17
Koong, A.18
Fuchs, S.Y.19
Diehl, J.A.20
Mills, I.G.21
Ruggero, D.22
Koumenis, C.23
more..
-
26
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
Hetz C, Chevet E, Harding HP. Targeting the unfolded protein response in disease. Nat Rev Drug Discov 12: 703-719, 2013.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
27
-
-
84899139079
-
Endoplasmic reticulum stress-activated transcription factor ATF6alpha requires the disulfide isomerase PDIA5 to modulate chemoresistance
-
Higa A, Taouji S, Lhomond S, Jensen D, Fernandez-Zapico ME, Simpson JC, Pasquet JM, Schekman R, Chevet E. Endoplasmic reticulum stress-activated transcription factor ATF6alpha requires the disulfide isomerase PDIA5 to modulate chemoresistance. Mol Cell Biol 34: 1839-1849, 2014.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 1839-1849
-
-
Higa, A.1
Taouji, S.2
Lhomond, S.3
Jensen, D.4
Fernandez-Zapico, M.E.5
Simpson, J.C.6
Pasquet, J.M.7
Schekman, R.8
Chevet, E.9
-
28
-
-
84875811673
-
IPK-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose
-
IPK-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose. Mol Cell 49: 1049-1059, 2013.
-
(2013)
Mol Cell
, vol.49
, pp. 1049-1059
-
-
Huber, A.L.1
Lebeau, J.2
Guillaumot, P.3
Petrilli, V.4
Malek, M.5
Chilloux, J.6
Fauvet, F.7
Payen-Gay, L.8
Kfoury, A.9
Renno, T.10
Chevet, E.11
Manié, S.12
-
29
-
-
34447651331
-
Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines
-
Igarashi T, Izumi H, Uchiumi T, Nishio K, Arao T, Tanabe M, Uramoto H, Sugio K, Yasumoto K, Sasaguri Y, Wang KY, Otsuji Y, Kohno K. Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines. Oncogene 26: 4749-4760, 2007.
-
(2007)
Oncogene
, vol.26
, pp. 4749-4760
-
-
Igarashi, T.1
Izumi, H.2
Uchiumi, T.3
Nishio, K.4
Arao, T.5
Tanabe, M.6
Uramoto, H.7
Sugio, K.8
Yasumoto, K.9
Sasaguri, Y.10
Wang, K.Y.11
Otsuji, Y.12
Kohno, K.13
-
30
-
-
0037385313
-
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
-
Iwakoshi NN, Lee AH, Vallabhajosyula P, Otipoby KL, Rajewsky K, Glimcher LH. Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1. Nat Immunol 4: 321- 329, 2003.
-
(2003)
Nat Immunol
, vol.4
, pp. 321-329
-
-
Iwakoshi, N.N.1
Lee, A.H.2
Vallabhajosyula, P.3
Otipoby, K.L.4
Rajewsky, K.5
Glimcher, L.H.6
-
31
-
-
84901005666
-
VEGF signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress
-
Karali E, Bellou S, Stellas D, Klinakis A, Murphy C, Fotsis T. VEGF signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress. Mol Cell 54: 559-572, 2014.
-
(2014)
Mol Cell
, vol.54
, pp. 559-572
-
-
Karali, E.1
Bellou, S.2
Stellas, D.3
Klinakis, A.4
Murphy, C.5
Fotsis, T.6
-
32
-
-
1542304646
-
Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation
-
Kebache S, Cardin E, Nguyen DT, Chevet E, Larose L. Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation. J Biol Chem 279: 9662-9671, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 9662-9671
-
-
Kebache, S.1
Cardin, E.2
Nguyen, D.T.3
Chevet, E.4
Larose, L.5
-
33
-
-
0023852783
-
The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins
-
Kozutsumi Y, Segal M, Normington K, Gething MJ, Sambrook J. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature 332: 462-464, 1988.
-
(1988)
Nature
, vol.332
, pp. 462-464
-
-
Kozutsumi, Y.1
Segal, M.2
Normington, K.3
Gething, M.J.4
Sambrook, J.5
-
34
-
-
34248571826
-
GRP78 induction in cancer: Therapeutic and prognostic implications
-
Lee AS. GRP78 induction in cancer: therapeutic and prognostic implications. Cancer Res 67: 3496-3499, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 3496-3499
-
-
Lee, A.S.1
-
35
-
-
84876932914
-
FGF-2 prevents cancer cells from ER stress-mediated apoptosis via enhancing proteasome-mediated Nck degradation
-
Li B, Pi Z, Liu L, Zhang B, Huang X, Hu P, Chevet E, Yi P, Liu J. FGF-2 prevents cancer cells from ER stress-mediated apoptosis via enhancing proteasome-mediated Nck degradation. Biochem J 452: 139-145, 2013.
-
(2013)
Biochem J
, vol.452
, pp. 139-145
-
-
Li, B.1
Pi, Z.2
Liu, L.3
Zhang, B.4
Huang, X.5
Hu, P.6
Chevet, E.7
Yi, P.8
Liu, J.9
-
36
-
-
84903749341
-
Cell death. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
-
Lu M, Lawrence DA, Marsters S, Acosta-Alvear D, Kimmig P, Mendez AS, Paton AW, Paton JC, Walter P, Ashkenazi A. Cell death. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science 345: 98-101, 2014.
-
(2014)
Science
, vol.345
, pp. 98-101
-
-
Lu, M.1
Lawrence, D.A.2
Marsters, S.3
Acosta-Alvear, D.4
Kimmig, P.5
Mendez, A.S.6
Paton, A.W.7
Paton, J.C.8
Walter, P.9
Ashkenazi, A.10
-
37
-
-
10344222124
-
The role of the unfolded protein response in tumour development: Friend or foe?
-
Ma Y, Hendershot LM. The role of the unfolded protein response in tumour development: friend or foe? Nat Rev Cancer 4: 966-977, 2004.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
38
-
-
84899937866
-
Getting RIDD of RNA: IRE1 in cell fate regulation
-
Maurel M, Chevet E, Tavernier J, Gerlo S. Getting RIDD of RNA: IRE1 in cell fate regulation. Trends Biochem Sci 39: 245-254, 2014.
-
(2014)
Trends Biochem Sci
, vol.39
, pp. 245-254
-
-
Maurel, M.1
Chevet, E.2
Tavernier, J.3
Gerlo, S.4
-
39
-
-
84902343965
-
Dppa5 improves hematopoietic stem cell activity by reducing endoplasmic reticulum stress
-
Miharada K, Sigurdsson V, Karlsson S. Dppa5 improves hematopoietic stem cell activity by reducing endoplasmic reticulum stress. Cell Rep 7: 1381-1392, 2014.
-
(2014)
Cell Rep
, vol.7
, pp. 1381-1392
-
-
Miharada, K.1
Sigurdsson, V.2
Karlsson, S.3
-
40
-
-
36348943088
-
Integrated endoplasmic reticulum stress responses in cancer
-
Moenner M, Pluquet O, Bouchecareilh M, Chevet E. Integrated endoplasmic reticulum stress responses in cancer. Cancer Res 67: 10631-10634, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 10631-10634
-
-
Moenner, M.1
Pluquet, O.2
Bouchecareilh, M.3
Chevet, E.4
-
41
-
-
84908665169
-
ER stress cooperates with hypernutrition to trigger TNFdependent spontaneous HCC development
-
Nakagawa H, Umemura A, Taniguchi K, Font-Burgada J, Dhar D, Ogata H, Zhong Z, Valasek MA, Seki E, Hidalgo J, Koike K, Kaufman RJ, Karin M. ER stress cooperates with hypernutrition to trigger TNFdependent spontaneous HCC development. Cancer Cell 26: 331-343, 2014.
-
(2014)
Cancer Cell
, vol.26
, pp. 331-343
-
-
Nakagawa, H.1
Umemura, A.2
Taniguchi, K.3
Font-Burgada, J.4
Dhar, D.5
Ogata, H.6
Zhong, Z.7
Valasek, M.A.8
Seki, E.9
Hidalgo, J.10
Koike, K.11
Kaufman, R.J.12
Karin, M.13
-
42
-
-
4344598305
-
Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress
-
Nguyen DT, Kebache S, Fazel A, Wong HN, Jenna S, Emadali A, Lee EH, Bergeron JJ, Kaufman RJ, Larose L, Chevet E. Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress. Mol Biol Cell 15: 4248-4260, 2004.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 4248-4260
-
-
Nguyen, D.T.1
Kebache, S.2
Fazel, A.3
Wong, H.N.4
Jenna, S.5
Emadali, A.6
Lee, E.H.7
Bergeron, J.J.8
Kaufman, R.J.9
Larose, L.10
Chevet, E.11
-
43
-
-
84885437087
-
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells
-
Niederreiter L, Fritz TM, Adolph TE, Krismer AM, Offner FA, Tschurtschenthaler M, Flak MB, Hosomi S, Tomczak MF, Kaneider NC, Sarcevic E, Kempster SL, Raine T, Esser D, Rosenstiel P, Kohno K, Iwawaki T, Tilg H, Blumberg RS, Kaser A. ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells. J Exp Med 210: 2041-2056, 2013.
-
(2013)
J Exp Med
, vol.210
, pp. 2041-2056
-
-
Niederreiter, L.1
Fritz, T.M.2
Adolph, T.E.3
Krismer, A.M.4
Offner, F.A.5
Tschurtschenthaler, M.6
Flak, M.B.7
Hosomi, S.8
Tomczak, M.F.9
Kaneider, N.C.10
Sarcevic, E.11
Kempster, S.L.12
Raine, T.13
Esser, D.14
Rosenstiel, P.15
Kohno, K.16
Iwawaki, T.17
Tilg, H.18
Blumberg, R.S.19
Kaser, A.20
more..
-
44
-
-
84881055345
-
Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response
-
Palorini R, Cammarata FP, Balestrieri C, Monestiroli A, Vasso M, Gelfi C, Alberghina L, Chiaradonna F. Glucose starvation induces cell death in K-ras-transformed cells by interfering with the hexosamine biosynthesis pathway and activating the unfolded protein response. Cell Death Dis 4: e732, 2013.
-
(2013)
Cell Death Dis
, vol.4
-
-
Palorini, R.1
Cammarata, F.P.2
Balestrieri, C.3
Monestiroli, A.4
Vasso, M.5
Gelfi, C.6
Alberghina, L.7
Chiaradonna, F.8
-
45
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA, Jr., Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW. An integrated genomic analysis of human glioblastoma multiforme. Science 321: 1807-1812, 2008.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Siu, I.M.9
Gallia, G.L.10
Olivi, A.11
McLendon, R.12
Rasheed, B.A.13
Keir, S.14
Nikolskaya, T.15
Nikolsky, Y.16
Busam, D.A.17
Tekleab, H.18
Diaz, L.A.19
Hartigan, J.20
Smith, D.R.21
Strausberg, R.L.22
Marie, S.K.23
Shinjo, S.M.24
Yan, H.25
Riggins, G.J.26
Bigner, D.D.27
Karchin, R.28
Papadopoulos, N.29
Parmigiani, G.30
Vogelstein, B.31
Velculescu, V.E.32
Kinzler, K.W.33
more..
-
46
-
-
84881436099
-
Posttranscriptional regulation of PER1 underlies the oncogenic function of IREalpha
-
Pluquet O, Dejeans N, Bouchecareilh M, Lhomond S, Pineau R, Higa A, Delugin M, Combe C, Loriot S, Cubel G, Dugot-Senant N, Vital A, Loiseau H, Gosline SJ, Taouji S, Hallett M, Sarkaria JN, Anderson K, Wu W, Rodriguez FJ, Rosenbaum J, Saltel F, Fernandez-Zapico ME, Chevet E. Posttranscriptional regulation of PER1 underlies the oncogenic function of IREalpha. Cancer Res 73: 4732-4743, 2013.
-
(2013)
Cancer Res
, vol.73
, pp. 4732-4743
-
-
Pluquet, O.1
Dejeans, N.2
Bouchecareilh, M.3
Lhomond, S.4
Pineau, R.5
Higa, A.6
Delugin, M.7
Combe, C.8
Loriot, S.9
Cubel, G.10
Dugot-Senant, N.11
Vital, A.12
Loiseau, H.13
Gosline, S.J.14
Taouji, S.15
Hallett, M.16
Sarkaria, J.N.17
Anderson, K.18
Wu, W.19
Rodriguez, F.J.20
Rosenbaum, J.21
Saltel, F.22
Fernandez-Zapico, M.E.23
Chevet, E.24
more..
-
47
-
-
84902191074
-
Watching the clock: Endoplasmic reticulum-mediated control of circadian rhythms in cancer
-
Pluquet O, Dejeans N, Chevet E. Watching the clock: endoplasmic reticulum-mediated control of circadian rhythms in cancer. Ann Med 46: 233-243, 2014.
-
(2014)
Ann Med
, vol.46
, pp. 233-243
-
-
Pluquet, O.1
Dejeans, N.2
Chevet, E.3
-
48
-
-
84869027086
-
ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation
-
Qing G, Li B, Vu A, Skuli N, Walton ZE, Liu X, Mayes PA, Wise DR, Thompson CB, Maris JM, Hogarty MD, Simon MC. ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. Cancer Cell 22: 631-644, 2012.
-
(2012)
Cancer Cell
, vol.22
, pp. 631-644
-
-
Qing, G.1
Li, B.2
Vu, A.3
Skuli, N.4
Walton, Z.E.5
Liu, X.6
Mayes, P.A.7
Wise, D.R.8
Thompson, C.B.9
Maris, J.M.10
Hogarty, M.D.11
Simon, M.C.12
-
49
-
-
85027932030
-
HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress
-
Rouault-Pierre K, Lopez-Onieva L, Foster K, Anjos-Afonso F, Lamrissi- Garcia I, Serrano-Sanchez M, Mitter R, Ivanovic Z, de Verneuil H, Gribben J, Taussig D, Rezvani HR, Mazurier F, Bonnet D. HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress. Cell Stem Cell 13: 549-563, 2013.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 549-563
-
-
Rouault-Pierre, K.1
Lopez-Onieva, L.2
Foster, K.3
Anjos-Afonso, F.4
Lamrissi-Garcia, I.5
Serrano-Sanchez, M.6
Mitter, R.7
Ivanovic, Z.8
de Verneuil, H.9
Gribben, J.10
Taussig, D.11
Rezvani, H.R.12
Mazurier, F.13
Bonnet, D.14
-
50
-
-
77953153048
-
Regulation of basal cellular physiology by the homeostatic unfolded protein response
-
Rutkowski DT, Hegde RS. Regulation of basal cellular physiology by the homeostatic unfolded protein response. J Cell Biol 189: 783-794, 2010.
-
(2010)
J Cell Biol
, vol.189
, pp. 783-794
-
-
Rutkowski, D.T.1
Hegde, R.S.2
-
51
-
-
48749105093
-
ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo
-
Schewe DM, Aguirre-Ghiso JA. ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo. Proc Natl Acad Sci USA 105: 10519-10524, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10519-10524
-
-
Schewe, D.M.1
Aguirre-Ghiso, J.A.2
-
52
-
-
75149165640
-
Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth
-
Spiotto MT, Banh A, Papandreou I, Cao H, Galvez MG, Gurtner GC, Denko NC, Le QT, Koong AC. Imaging the unfolded protein response in primary tumors reveals microenvironments with metabolic variations that predict tumor growth. Cancer Res 70: 78-88, 2010.
-
(2010)
Cancer Res
, vol.70
, pp. 78-88
-
-
Spiotto, M.T.1
Banh, A.2
Papandreou, I.3
Cao, H.4
Galvez, M.G.5
Gurtner, G.C.6
Denko, N.C.7
Le, Q.T.8
Koong, A.C.9
-
53
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol 13: 184-190, 2011.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
54
-
-
84902343044
-
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
-
van Galen P, Kreso A, Mbong N, Kent DG, Fitzmaurice T, Chambers JE, Xie S, Laurenti E, Hermans K, Eppert K, Marciniak SJ, Goodall JC, Green AR, Wouters BG, Wienholds E, Dick JE. The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress. Nature 510: 268-272, 2014.
-
(2014)
Nature
, vol.510
, pp. 268-272
-
-
van Galen, P.1
Kreso, A.2
Mbong, N.3
Kent, D.G.4
Fitzmaurice, T.5
Chambers, J.E.6
Xie, S.7
Laurenti, E.8
Hermans, K.9
Eppert, K.10
Marciniak, S.J.11
Goodall, J.C.12
Green, A.R.13
Wouters, B.G.14
Wienholds, E.15
Dick, J.E.16
-
55
-
-
78649615070
-
A protective role for CD154 in hepatic steatosis in mice
-
Villeneuve J, Lepreux S, Mulot A, Berard AM, Higa-Nishiyama A, Costet P, De Ledinghen V, Bioulac-Sage P, Balabaud C, Nurden AT, Rosenbaum J, Chevet E, Ripoche J. A protective role for CD154 in hepatic steatosis in mice. Hepatology 52: 1968-1979, 2010.
-
(2010)
Hepatology
, vol.52
, pp. 1968-1979
-
-
Villeneuve, J.1
Lepreux, S.2
Mulot, A.3
Berard, A.M.4
Higa-Nishiyama, A.5
Costet, P.6
De Ledinghen, V.7
Bioulac-Sage, P.8
Balabaud, C.9
Nurden, A.T.10
Rosenbaum, J.11
Chevet, E.12
Ripoche, J.13
-
56
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 334: 1081-1086, 2011.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
57
-
-
84863740827
-
The impact of the unfolded protein response on human disease
-
Wang S, Kaufman RJ. The impact of the unfolded protein response on human disease. J Cell Biol 197: 857-867, 2012.
-
(2012)
J Cell Biol
, vol.197
, pp. 857-867
-
-
Wang, S.1
Kaufman, R.J.2
-
58
-
-
84896382541
-
Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway
-
Wang ZV, Deng Y, Gao N, Pedrozo Z, Li DL, Morales CR, Criollo A, Luo X, Tan W, Jiang N, Lehrman MA, Rothermel BA, Lee AH, Lavandero S, Mammen PP, Ferdous A, Gillette TG, Scherer PE, Hill JA. Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway. Cell 156: 1179 -1192, 2014.
-
(2014)
Cell
, vol.156
, pp. 1179-1192
-
-
Wang, Z.V.1
Deng, Y.2
Gao, N.3
Pedrozo, Z.4
Li, D.L.5
Morales, C.R.6
Criollo, A.7
Luo, X.8
Tan, W.9
Jiang, N.10
Lehrman, M.A.11
Rothermel, B.A.12
Lee, A.H.13
Lavandero, S.14
Mammen, P.P.15
Ferdous, A.16
Gillette, T.G.17
Scherer, P.E.18
Hill, J.A.19
-
59
-
-
73349141743
-
Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling
-
Woo CW, Cui D, Arellano J, Dorweiler B, Harding H, Fitzgerald KA, Ron D, Tabas I. Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling. Nat Cell Biol 11: 1473-1480, 2009.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1473-1480
-
-
Woo, C.W.1
Cui, D.2
Arellano, J.3
Dorweiler, B.4
Harding, H.5
Fitzgerald, K.A.6
Ron, D.7
Tabas, I.8
-
60
-
-
84856487878
-
Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B
-
Woo CW, Kutzler L, Kimball SR, Tabas I. Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B. Nat Cell Biol 14: 192-200, 2012.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 192-200
-
-
Woo, C.W.1
Kutzler, L.2
Kimball, S.R.3
Tabas, I.4
-
61
-
-
84896846085
-
561 negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content
-
561 negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content. Mol Biol Cell 25: 702-711, 2013.
-
(2013)
Mol Biol Cell
, vol.25
, pp. 702-711
-
-
Yamani, L.1
Latreille, M.2
Larose, L.3
|