-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Cairncross JG, Eisenhauer E and Mirimanoff RO: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352(10): 987-996, 2005. (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den, B.M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
2
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
DOI 10.1038/35102167
-
Reya T, Morrison SJ, Clarke MF and Weissman IL: Stem cells, cancer, and cancer stem cells. Nature 414(6859): 105-111, 2001. (Pubitemid 33041634)
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
3
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J and Dirks PB: Identification of a cancer stem cell in human brain tumors. Cancer Res 63(18): 5821-5828, 2003. (Pubitemid 37187480)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
4
-
-
34249332411
-
- glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles
-
DOI 10.1158/0008-5472.CAN-06-4180
-
Beier D, Hau P, Proescholdt M, Lohmeier A, Wischhusen J, Oefner PJ, Aigner L, Brawanski A, Bogdahn U and Beier CP: CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 67(9): 4010-4015, 2007. (Pubitemid 46815044)
-
(2007)
Cancer Research
, vol.67
, Issue.9
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
Lohmeier, A.4
Wischhusen, J.5
Oefner, P.J.6
Aigner, L.7
Brawanski, A.8
Bogdahn, U.9
Beier, C.P.10
-
5
-
-
65349115320
-
SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
-
Son MJ, Woolard K, Nam DH, Lee J and Fine HA: SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 4(5): 440-452, 2009.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.5
, pp. 440-452
-
-
Son, M.J.1
Woolard, K.2
Nam, D.H.3
Lee, J.4
Fine, H.A.5
-
6
-
-
77956245743
-
Integrin alpha 6 regulates glioblastoma stem cells
-
Lathia JD, Gallagher J, Heddleston JM, Wang J, Eyler CE, Macswords J, Wu Q, Vasanji A, McLendon RE, Hjelmeland AB and Rich JN: Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell 6(5): 421-432, 2010.
-
(2010)
Cell Stem Cell
, vol.6
, Issue.5
, pp. 421-432
-
-
Lathia, J.D.1
Gallagher, J.2
Heddleston, J.M.3
Wang, J.4
Eyler, C.E.5
Macswords, J.6
Wu, Q.7
Vasanji, A.8
McLendon, R.E.9
Hjelmeland, A.B.10
Rich, J.N.11
-
7
-
-
60849117508
-
PTEN/PI3K/AKT pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW and Holland EC: PTEN/PI3K/AKT pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell 4(3): 226-235, 2009.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.3
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
Holland, E.C.7
-
8
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
DOI 10.1158/0008-5472.CAN-04-1364
-
Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, De Vitis S, Fiocco R, Foroni C, Dimeco F and Vescovi A: Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64(19): 7011-7021, 2004. (Pubitemid 39331011)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
Fiocco, R.7
Foroni, C.8
Dimeco, F.9
Vescovi, A.10
-
9
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
DOI 10.1016/j.ccr.2006.03.030, PII S1535610806001176
-
Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, Donin NM, Pastorino S, Purow BW, Christopher N, Zhang W, Park JK and Fine HA: Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9(5): 391-403, 2006. (Pubitemid 43668737)
-
(2006)
Cancer Cell
, vol.9
, Issue.5
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
Li, A.4
Su, Q.5
Donin, N.M.6
Pastorino, S.7
Purow, B.W.8
Christopher, N.9
Zhang, W.10
Park, J.K.11
Fine, H.A.12
-
10
-
-
66049085403
-
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
-
Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A and Dirks P: Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell 4(6): 568-580, 2009.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.6
, pp. 568-580
-
-
Pollard, S.M.1
Yoshikawa, K.2
Clarke, I.D.3
Danovi, D.4
Stricker, S.5
Russell, R.6
Bayani, J.7
Head, R.8
Lee, M.9
Bernstein, M.10
Squire, J.A.11
Smith, A.12
Dirks, P.13
-
11
-
-
78149299837
-
Proteasome inhibitors: Dozens of molecules and still counting
-
de Bettignies G and Coux O: Proteasome inhibitors: Dozens of molecules and still counting. Biochimie 92(11): 1530-1545, 2010.
-
(2010)
Biochimie
, vol.92
, Issue.11
, pp. 1530-1545
-
-
De Bettignies, G.1
Coux, O.2
-
12
-
-
0034062989
-
Proteasome inhibition: A new strategy in cancer treatment
-
DOI 10.1023/A:1006321828515
-
Adams J, Palombella VJ and Elliott PJ: Proteasome inhibition: a new strategy in cancer treatment. Investigational new drugs. 18(2): 109-121, 2000. (Pubitemid 30261285)
-
(2000)
Investigational New Drugs
, vol.18
, Issue.2
, pp. 109-121
-
-
Adams, J.1
Palombella, V.J.2
Elliott, P.J.3
-
13
-
-
79952194923
-
Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma
-
Phuphanich S, Supko JG, Carson KA, Grossman SA, Burt Nabors L, Mikkelsen T, Lesser G, Rosenfeld S, Desideri S and Olson JJ: Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma. J Neurooncol 100(1): 95-103, 2010.
-
(2010)
J Neurooncol
, vol.100
, Issue.1
, pp. 95-103
-
-
Phuphanich, S.1
Supko, J.G.2
Carson, K.A.3
Grossman, S.A.4
Burt Nabors, L.5
Mikkelsen, T.6
Lesser, G.7
Rosenfeld, S.8
Desideri, S.9
Olson, J.J.10
-
14
-
-
49349098483
-
Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy
-
Carew JS, Giles FJ and Nawrocki ST: Histone deacetylase inhibitors: mechanisms of cell death and promise in combination cancer therapy. Cancer lett 269(1): 7-17, 2008.
-
(2008)
Cancer Lett
, vol.269
, Issue.1
, pp. 7-17
-
-
Carew, J.S.1
Giles, F.J.2
Nawrocki, S.T.3
-
15
-
-
33745320974
-
Targeting histone deacetylase in cancer therapy
-
Lin HY, Chen CS, Lin SP and Weng JR: Targeting histone deacetylase in cancer therapy. Med Res Rev 26(4): 397-413, 2006.
-
(2006)
Med Res Rev
, vol.26
, Issue.4
, pp. 397-413
-
-
Lin, H.Y.1
Chen, C.S.2
Lin, S.P.3
Weng, J.R.4
-
16
-
-
34547864236
-
Histone deacetylase inhibitors: Molecular mechanisms of action
-
DOI 10.1038/sj.onc.1210620, PII 1210620
-
Xu WS, Parmigiani RB and Marks PA: Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 26(37): 5541-5552, 2007. (Pubitemid 47255934)
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5541-5552
-
-
Xu, W.S.1
Parmigiani, R.B.2
Marks, P.A.3
-
17
-
-
65349141942
-
Phase II trial of vorinostat in recurrent glioblastoma multiforme: A north central cancer treatment group study
-
Galanis E, Jaeckle KA, Maurer MJ, Reid JM, Ames MM, Hardwick JS, Reilly JF, Loboda A, Nebozhyn M, Fantin VR, Richon VM, Scheithauer B, Giannini C, Flynn PJ, Moore DF, Jr., Zwiebel J and Buckner JC: Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study. J Clin Oncol 27(12): 2052-2058, 2009.
-
(2009)
J Clin Oncol
, vol.27
, Issue.12
, pp. 2052-2058
-
-
Galanis, E.1
Jaeckle, K.A.2
Maurer, M.J.3
Reid, J.M.4
Ames, M.M.5
Hardwick, J.S.6
Reilly, J.F.7
Loboda, A.8
Nebozhyn, M.9
Fantin, V.R.10
Richon, V.M.11
Scheithauer, B.12
Giannini, C.13
Flynn, P.J.14
Moore Jr., D.F.15
Zwiebel, J.16
Buckner, J.C.17
-
18
-
-
77950543254
-
Epigenetic modifiers as anticancer drugs: Effectiveness of valproic acid in neural crest-derived tumor cells
-
Papi A, Ferreri AM, Rocchi P, Guerra F and Orlandi M: Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells. Anticancer Res 30(2): 535-540, 2010.
-
(2010)
Anticancer Res
, vol.30
, Issue.2
, pp. 535-540
-
-
Papi, A.1
Ferreri, A.M.2
Rocchi, P.3
Guerra, F.4
Orlandi, M.5
-
19
-
-
53049089057
-
Postradiation sensitization of the histone deacetylase inhibitor valproic acid
-
Chinnaiyan P, Cerna D, Burgan WE, Beam K, Williams ES, Camphausen K and Tofilon PJ: Postradiation sensitization of the histone deacetylase inhibitor valproic acid. Clin Cancer Res 14(17): 5410-5415, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.17
, pp. 5410-5415
-
-
Chinnaiyan, P.1
Cerna, D.2
Burgan, W.E.3
Beam, K.4
Williams, E.S.5
Camphausen, K.6
Tofilon, P.J.7
-
20
-
-
0033672431
-
Modifying histones to tame cancer: Clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors
-
Gore SD and Carducci MA: Modifying histones to tame cancer: clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors. Expert opinion on investigational drugs 9(12): 2923-2934, 2000.
-
(2000)
Expert Opinion on Investigational Drugs
, vol.9
, Issue.12
, pp. 2923-2934
-
-
Gore, S.D.1
Carducci, M.A.2
-
21
-
-
1942485780
-
Histone deacetylase inhibitor 4-phenylbutyrate modulates glial fibrillary acidic protein and connexin 43 expression, and enhances gap-junction communication, in human glioblastoma cells
-
DOI 10.1016/j.ejca.2003.11.034, PII S0959804904001005
-
Asklund T, Appelskog IB, Ammerpohl O, Ekstrom TJ and Almqvist PM: Histone deacetylase inhibitor 4-phenylbutyrate modulates glial fibrillary acidic protein and connexin 43 expression, and enhances gap-junction communication, in human glioblastoma cells. Eur J Cancer 40(7): 1073-1081, 2004. (Pubitemid 38496266)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.7
, pp. 1073-1081
-
-
Asklund, T.1
Appelskog, I.B.2
Ammerpohl, O.3
Ekstrom, T.J.4
Almqvist, P.M.5
-
22
-
-
34547154713
-
HDAC inhibition amplifies gap junction communication in neural progenitors: Potential for cell-mediated enzyme prodrug therapy
-
DOI 10.1016/j.yexcr.2007.05.004, PII S0014482707002194
-
Khan Z, Akhtar M, Asklund T, Juliusson B, Almqvist PM and Ekstrom TJ: HDAC inhibition amplifies gap junction communication in neural progenitors: potential for cell-mediated enzyme prodrug therapy. Exp Cell Res 313(13): 2958-2967, 2007. (Pubitemid 47126438)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.13
, pp. 2958-2967
-
-
Khan, Z.1
Akhtar, M.2
Asklund, T.3
Juliusson, B.4
Almqvist, P.M.5
Ekstrom, T.J.6
-
23
-
-
0034885248
-
A Phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies
-
Gilbert J, Baker SD, Bowling MK, Grochow L, Figg WD, Zabelina Y, Donehower RC and Carducci MA: A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies. Clin Cancer Res 7(8): 2292-2300, 2001. (Pubitemid 32751627)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.8
, pp. 2292-2300
-
-
Gilbert, J.1
Baker, S.D.2
Bowling, M.K.3
Grochow, L.4
Figg, W.D.5
Zabelina, Y.6
Donehower, R.C.7
Carducci, M.A.8
-
24
-
-
17844410310
-
Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: A dose escalation and pharmacologic study
-
DOI 10.1215/S1152851704000183
-
Phuphanich S, Baker SD, Grossman SA, Carson KA, Gilbert MR, Fisher JD and Carducci MA: Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: a dose escalation and pharmacologic study. Neuro-oncol 7(2): 177-182, 2005. (Pubitemid 40590517)
-
(2005)
Neuro-Oncology
, vol.7
, Issue.2
, pp. 177-182
-
-
Phuphanich, S.1
Baker, S.D.2
Grossman, S.A.3
Carson, K.A.4
Gilbert, M.R.5
Fisher, J.D.6
Carducci, M.A.7
-
25
-
-
77950909402
-
Combined proteasome and histone deacetylase inhibition attenuates epithelial-mesenchymal transition through E-cadherin in esophageal cancer cells
-
Taylor MD, Liu Y, Nagji AS, Theodosakis N and Jones DR: Combined proteasome and histone deacetylase inhibition attenuates epithelial-mesenchymal transition through E-cadherin in esophageal cancer cells. J Thorac Cardiovasc Surg 139(5): 1224-1232, 32 e1, 2010.
-
(2010)
J Thorac Cardiovasc Surg
, vol.139
, Issue.5
-
-
Taylor, M.D.1
Liu, Y.2
Nagji, A.S.3
Theodosakis, N.4
Jones, D.R.5
-
26
-
-
6344229760
-
Proteasome inhibition sensitizes nonsmall cell lung cancer to histone deacetylase inhibitorinduced apoptosis through the generation of reactive oxygen species
-
DOI 10.1016/j.jtcvs.2004.07.010, PII S0022522304009857
-
Denlinger CE, Rundall BK and Jones DR: Proteasome inhibition sensitizes non-small cell lung cancer to histone deacetylase inhibitor-induced apoptosis through the generation of reactive oxygen species. J Thorac Cardiovasc Surg 128(5): 740-748, 2004. (Pubitemid 39388930)
-
(2004)
Journal of Thoracic and Cardiovascular Surgery
, vol.128
, Issue.5
, pp. 740-748
-
-
Denlinger, C.E.1
Rundall, B.K.2
Jones, D.R.3
-
27
-
-
34249993174
-
SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib
-
DOI 10.1007/s10495-007-0063-y
-
Emanuele S, Lauricella M, Carlisi D, Vassallo B, D'Anneo A, Di Fazio P, Vento R and Tesoriere G: SAHA induces apoptosis in hepatoma cells and synergistically interacts with the proteasome inhibitor Bortezomib. Apoptosis 12(7): 1327-1338, 2007. (Pubitemid 46890392)
-
(2007)
Apoptosis
, vol.12
, Issue.7
, pp. 1327-1338
-
-
Emanuele, S.1
Lauricella, M.2
Carlisi, D.3
Vassallo, B.4
D'Anneo, A.5
Di, F.P.6
Vento, R.7
Tesoriere, G.8
-
28
-
-
38049126172
-
Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma
-
Heider U, von Metzler I, Kaiser M, Rosche M, Sterz J, Rotzer S, Rademacher J, Jakob C, Fleissner C, Kuckelkorn U, Kloetzel PM and Sezer O: Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma. Eur J Haematol 80(2): 133-142, 2008.
-
(2008)
Eur J Haematol
, vol.80
, Issue.2
, pp. 133-142
-
-
Heider, U.1
Von Metzler, I.2
Kaiser, M.3
Rosche, M.4
Sterz, J.5
Rotzer, S.6
Rademacher, J.7
Jakob, C.8
Fleissner, C.9
Kuckelkorn, U.10
Kloetzel, P.M.11
Sezer, O.12
-
29
-
-
59449084559
-
Combination of proteasome and HDAC inhibitors for uterine cervical cancer treatment
-
Lin Z, Bazzaro M, Wang MC, Chan KC, Peng S and Roden RB: Combination of proteasome and HDAC inhibitors for uterine cervical cancer treatment. Clin Cancer Res 15(2): 570-577, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.2
, pp. 570-577
-
-
Lin, Z.1
Bazzaro, M.2
Wang, M.C.3
Chan, K.C.4
Peng, S.5
Roden, R.B.6
-
30
-
-
60849106339
-
Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models
-
Pitts TM, Morrow M, Kaufman SA, Tentler JJ and Eckhardt SG: Vorinostat and bortezomib exert synergistic antiproliferative and proapoptotic effects in colon cancer cell models. Mol Cancer Ther 8(2): 342-349, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.2
, pp. 342-349
-
-
Pitts, T.M.1
Morrow, M.2
Kaufman, S.A.3
Tentler, J.J.4
Eckhardt, S.G.5
-
31
-
-
65349116082
-
Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in cutaneous T cell lymphoma
-
Heider U, Rademacher J, Lamottke B, Mieth M, Moebs M, von Metzler I, Assaf C and Sezer O: Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in cutaneous T cell lymphoma. Eur J Haematol 82(6): 440-449, 2009.
-
(2009)
Eur J Haematol
, vol.82
, Issue.6
, pp. 440-449
-
-
Heider, U.1
Rademacher, J.2
Lamottke, B.3
Mieth, M.4
Moebs, M.5
Von Metzler, I.6
Assaf, C.7
Sezer, O.8
-
32
-
-
68749093915
-
The proteasome inhibitor bortezomib interacts synergistically with the histone deacetylase inhibitor suberoylanilide hydroxamic acid to induce T-leukemia/lymphoma cells apoptosis
-
Zhang QL, Wang L, Zhang YW, Jiang XX, Yang F, Wu WL, Janin A, Chen Z, Shen ZX, Chen SJ and Zhao WL: The proteasome inhibitor bortezomib interacts synergistically with the histone deacetylase inhibitor suberoylanilide hydroxamic acid to induce T-leukemia/lymphoma cells apoptosis. Leukemia 23(8): 1507-1514, 2009.
-
(2009)
Leukemia
, vol.23
, Issue.8
, pp. 1507-1514
-
-
Zhang, Q.L.1
Wang, L.2
Zhang, Y.W.3
Jiang, X.X.4
Yang, F.5
Wu, W.L.6
Janin, A.7
Chen, Z.8
Shen, Z.X.9
Chen, S.J.10
Zhao, W.L.11
-
33
-
-
52949083797
-
Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells
-
Yu C, Friday BB, Yang L, Atadja P, Wigle D, Sarkaria J and Adjei AA: Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. Neuro Oncol 10(3): 309-319, 2008.
-
(2008)
Neuro Oncol
, vol.10
, Issue.3
, pp. 309-319
-
-
Yu, C.1
Friday, B.B.2
Yang, L.3
Atadja, P.4
Wigle, D.5
Sarkaria, J.6
Adjei, A.A.7
-
34
-
-
0028226371
-
Detection of tumor-specific cytotoxic drug activity in vitro using the fluorometric microculture cytotoxicity assay and primary cultures of tumor cells from patients
-
Nygren P, Fridborg H, Csoka K, Sundstrom C, de la Torre M, Kristensen J, Bergh J, Hagberg H, Glimelius B, Rastad J et al: Detection of tumor-specific cytotoxic drug activity in vitro using the fluorometric microculture cytotoxicity assay and primary cultures of tumor cells from patients. Int J Cancer 56(5): 715-720, 1994. (Pubitemid 24086775)
-
(1994)
International Journal of Cancer
, vol.56
, Issue.5
, pp. 715-720
-
-
Nygren, P.1
Fridborg, H.2
Csoka, K.3
Sundstrom, C.4
De La, T.M.5
Kristensen, J.6
Bergh, J.7
Hagberg, H.8
Glimelius, B.9
Rastad, J.10
Tholander, B.11
Larsson, R.12
-
35
-
-
79955477797
-
LRIG1 and the liar paradox in prostate cancer: A study of the expression and clinical significance of LRIG1 in prostate cancer
-
Thomasson M, Wang B, Hammarsten P, Dahlman A, Persson JL, Josefsson A, Stattin P, Granfors T, Egevad L, Henriksson R, Bergh A and Hedman H: LRIG1 and the liar paradox in prostate cancer: A study of the expression and clinical significance of LRIG1 in prostate cancer. Int J Cancer 128(12): 2843-2852, 2011.
-
(2011)
Int J Cancer
, vol.128
, Issue.12
, pp. 2843-2852
-
-
Thomasson, M.1
Wang, B.2
Hammarsten, P.3
Dahlman, A.4
Persson, J.L.5
Josefsson, A.6
Stattin, P.7
Granfors, T.8
Egevad, L.9
Henriksson, R.10
Bergh, A.11
Hedman, H.12
-
36
-
-
58049208190
-
Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis
-
Fotheringham S, Epping MT, Stimson L, Khan O, Wood V, Pezzella F, Bernards R and La Thangue NB: Genome-wide loss-of-function screen reveals an important role for the proteasome in HDAC inhibitor-induced apoptosis. Cancer Cell 15(1): 57-66, 2009.
-
(2009)
Cancer Cell
, vol.15
, Issue.1
, pp. 57-66
-
-
Fotheringham, S.1
Epping, M.T.2
Stimson, L.3
Khan, O.4
Wood, V.5
Pezzella, F.6
Bernards, R.7
La Thangue, N.B.8
-
37
-
-
41149163821
-
The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids
-
DOI 10.1038/sj.onc.1210850, PII 1210850
-
De Witt Hamer PC, Van Tilborg AA, Eijk PP, Sminia P, Troost D, Van Noorden CJ, Ylstra B and Leenstra S: The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids. Oncogene 27(14): 2091-2096, 2008. (Pubitemid 351442747)
-
(2008)
Oncogene
, vol.27
, Issue.14
, pp. 2091-2096
-
-
De Witt, H.P.C.1
Van Tilborg, A.A.G.2
Eijk, P.P.3
Sminia, P.4
Troost, D.5
Van Noorden, C.J.F.6
Ylstra, B.7
Leenstra, S.8
-
38
-
-
40949128188
-
Phase I and pharmacokinetic study of bortezomib in combination with idarubicinand cytarabine in patients with acute myelogenous leukemia
-
DOI 10.1158/1078-0432.CCR-07-4626
-
Attar EC, De Angelo DJ, Supko JG, D'Amato F, Zahrieh D, Sirulnik A, Wadleigh M, Ballen KK, McAfee S, Miller KB, Levine J, Galinsky I, Trehu EG, Schenkein D, Neuberg D, Stone RM and Amrein PC: Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia. Clin Cancer Res 14(5): 1446-1454, 2008. (Pubitemid 351413928)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.5
, pp. 1446-1454
-
-
Attar, E.C.1
DeAngelo, D.J.2
Supko, J.G.3
D'Amato, F.4
Zahrieh, D.5
Sirulnik, A.6
Wadleigh, M.7
Ballen, K.K.8
McAfee, S.9
Miller, K.B.10
Levine, J.11
Galinsky, I.12
Trehu, E.G.13
Schenkein, D.14
Neuberg, D.15
Stone, R.M.16
Amrein, P.C.17
-
39
-
-
21244464349
-
Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer
-
DOI 10.1200/JCO.2005.14.167
-
Kelly WK, O'Connor OA, Krug LM, Chiao JH, Heaney M, Curley T, MacGregore-Cortelli B, Tong W, Secrist JP, Schwartz L, Richardson S, Chu E, Olgac S, Marks PA, Scher H and Richon VM: Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer. J Clin Oncol 23(17): 3923-3931, 2005. (Pubitemid 46218695)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.17
, pp. 3923-3931
-
-
Kelly, W.K.1
O'Connor, O.A.2
Krug, L.M.3
Chiao, J.H.4
Heaney, M.5
Curley, T.6
MacGregore-Cortelli, B.7
Tong, W.8
Secrist, J.P.9
Schwartz, L.10
Richardson, S.11
Chu, E.12
Olgac, S.13
Marks, P.A.14
Scher, H.15
Richon, V.M.16
-
40
-
-
34250696097
-
Phase I and pharmacokinetic study of vorinostat, a histone deacetylase inhibitor, in combination with carboplatin and paclitaxel for advanced solid malignancies
-
DOI 10.1158/1078-0432.CCR-07-0162
-
Ramalingam SS, Parise RA, Ramanathan RK, Lagattuta TF, Musguire LA, Stoller RG, Potter DM, Argiris AE, Zwiebel JA, Egorin MJ and Belani CP: Phase I and pharmacokinetic study of vorinostat, a histone deacetylase inhibitor, in combination with carboplatin and paclitaxel for advanced solid malignancies. Clin Cancer Res 13(12): 3605-3610, 2007. (Pubitemid 46955122)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.12
, pp. 3605-3610
-
-
Ramalingam, S.S.1
Parise, R.A.2
Ramananthan, R.K.3
Lagattuta, T.F.4
Musguire, L.A.5
Stoller, R.G.6
Potter, D.M.7
Argiris, A.E.8
Zwiebel, J.A.9
Egorin, M.J.10
Belani, C.P.11
-
41
-
-
0037742375
-
Valproate: A reappraisal of its pharmacodynamic properties and mechanisms of action
-
Loscher W: Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action. Prog Neurobiol 58(1): 31- 59, 1999.
-
(1999)
Prog Neurobiol
, vol.58
, Issue.1
, pp. 31-59
-
-
Loscher, W.1
-
42
-
-
84859538161
-
Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: A north central cancer treatment group study
-
Friday BB, Anderson SK, Buckner J, Yu C, Giannini C, Geoffroy F, Schwerkoske J, Mazurczak M, Gross H, Pajon E, Jaeckle K and Galanis E: Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study. Neuro-oncol 14(2): 215-221, 2012.
-
(2012)
Neuro-oncol
, vol.14
, Issue.2
, pp. 215-221
-
-
Friday, B.B.1
Anderson, S.K.2
Buckner, J.3
Yu, C.4
Giannini, C.5
Geoffroy, F.6
Schwerkoske, J.7
Mazurczak, M.8
Gross, H.9
Pajon, E.10
Jaeckle, K.11
Galanis, E.12
-
43
-
-
79951674942
-
The cancer stem cell hypothesis: Failures and pitfalls
-
discussion 45
-
Rahman M, Deleyrolle L, Vedam-Mai V, Azari H, Abd-El-Barr M and Reynolds BA: The cancer stem cell hypothesis: failures and pitfalls. Neurosurgery 68(2): 531-545; discussion 45, 2011.
-
(2011)
Neurosurgery
, vol.68
, Issue.2
, pp. 531-545
-
-
Rahman, M.1
Deleyrolle, L.2
Vedam-Mai, V.3
Azari, H.4
Abd-El-Barr, M.5
Reynolds, B.A.6
-
44
-
-
80052023881
-
The neurobiology of gliomas: From cell biology to the development of therapeutic approaches
-
Westphal M and Lamszus K: The neurobiology of gliomas: from cell biology to the development of therapeutic approaches. Nat Rev Neurosci 12(9): 495-508, 2011.
-
(2011)
Nat Rev Neurosci
, vol.12
, Issue.9
, pp. 495-508
-
-
Westphal, M.1
Lamszus, K.2
|