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Volumn , Issue , 2014, Pages 413-458

Metabolites and Transformation Products of Pharmaceuticals in the Aquatic Environment as Contaminants of Emerging Concern

Author keywords

Advanced oxidation processes; Biotic and abiotic degradation; Metabolites; Pharmaceuticals; Transformation products

Indexed keywords

BIOMOLECULES; DRUG PRODUCTS; EFFLUENTS; METABOLITES; PHOTOLYSIS; PHYSIOLOGY; SEWAGE TREATMENT PLANTS;

EID: 84982263406     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118339558.ch14     Document Type: Chapter
Times cited : (37)

References (187)
  • 1
    • 0035697218 scopus 로고    scopus 로고
    • Human pharmaceuticals in the aquatic environment a review
    • Jones, O.A.H., Voulvoulis, N., and Lester, J.N. (2001) Human pharmaceuticals in the aquatic environment a review. Environmental Technology, 22, 1383-1394.
    • (2001) Environmental Technology , vol.22 , pp. 1383-1394
    • Jones, O.A.H.1    Voulvoulis, N.2    Lester, J.N.3
  • 2
    • 35848934144 scopus 로고    scopus 로고
    • Structural characterization of photodegradation products of enalapril and its metabolite enalaprilat obtained under simulated environmental conditions by hybrid quadrupole-linear ion trap-MS and quadrupole-time-of-flight-MS
    • Perez, S., Eichhorn, P., and Barcelo, D. (2007) Structural characterization of photodegradation products of enalapril and its metabolite enalaprilat obtained under simulated environmental conditions by hybrid quadrupole-linear ion trap-MS and quadrupole-time-of-flight-MS. Analytical Chemistry, 79, 8293-8300.
    • (2007) Analytical Chemistry , vol.79 , pp. 8293-8300
    • Perez, S.1    Eichhorn, P.2    Barcelo, D.3
  • 3
    • 33646157485 scopus 로고    scopus 로고
    • Trace determination of b-lactam antibiotics in surface water and urban wastewater using liquid chromatography combined with electrospray tandem mass spectrometry
    • Cha, J.M., Yang, S., and Carlson, K.H. (2006) Trace determination of b-lactam antibiotics in surface water and urban wastewater using liquid chromatography combined with electrospray tandem mass spectrometry. Journal of Chromatography. A, 1115, 46-57.
    • (2006) Journal of Chromatography. A , vol.1115 , pp. 46-57
    • Cha, J.M.1    Yang, S.2    Carlson, K.H.3
  • 4
    • 66049130018 scopus 로고    scopus 로고
    • Rapid analysis of 21 antibiotics of multiple classes in municipal wastewater using ultra performance liquid chromatography-tandem mass spectrometry
    • Li, B., Zhang, T., Xu, Z., and Fang, H.H.P. (2009) Rapid analysis of 21 antibiotics of multiple classes in municipal wastewater using ultra performance liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta, 645, 64-72.
    • (2009) Analytica Chimica Acta , vol.645 , pp. 64-72
    • Li, B.1    Zhang, T.2    Xu, Z.3    Fang, H.H.P.4
  • 5
    • 78149246639 scopus 로고    scopus 로고
    • A tiered procedure for assessing the formation of biotransformation products of pharmaceuticals and biocides during activated sludge treatment
    • Kern, S., Baumgartner, R., Helbling, D.E. et al. (2010) A tiered procedure for assessing the formation of biotransformation products of pharmaceuticals and biocides during activated sludge treatment. Journal of Environmental Monitoring, 12, 2100-2111.
    • (2010) Journal of Environmental Monitoring , vol.12 , pp. 2100-2111
    • Kern, S.1    Baumgartner, R.2    Helbling, D.E.3
  • 6
    • 80555126765 scopus 로고    scopus 로고
    • Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes - Degradation, elucidation of byproducts and assessment of their biological potency
    • Fatta-Kassinos, D., Vasquez, M.I., and Kümmerer, K. (2011) Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes - Degradation, elucidation of byproducts and assessment of their biological potency. Chemosphere, 85, 693-709.
    • (2011) Chemosphere , vol.85 , pp. 693-709
    • Fatta-Kassinos, D.1    Vasquez, M.I.2    Kümmerer, K.3
  • 7
    • 1942517950 scopus 로고    scopus 로고
    • Standardized tests fail to assess the effects of antibiotics on environmental bacteria
    • Kümmerer, K., Alexy, R., Hüttig, J., and Schöll, A. (2004) Standardized tests fail to assess the effects of antibiotics on environmental bacteria. Water Research, 38, 2111-2116.
    • (2004) Water Research , vol.38 , pp. 2111-2116
    • Kümmerer, K.1    Alexy, R.2    Hüttig, J.3    Schöll, A.4
  • 8
    • 0037369490 scopus 로고    scopus 로고
    • Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment
    • Andreozzi, R., Raffaele, M., and Nicklas, P. (2003) Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment. Chemosphere, 50, 1319-1330.
    • (2003) Chemosphere , vol.50 , pp. 1319-1330
    • Andreozzi, R.1    Raffaele, M.2    Nicklas, P.3
  • 9
    • 58349088276 scopus 로고    scopus 로고
    • Removal of residual pharmaceuticals from aqueous systems by advanced oxidation processes
    • Klavarioti, M., Mantzavinos, D., and Kassinos, D. (2009) Removal of residual pharmaceuticals from aqueous systems by advanced oxidation processes. Environment International, 35, 402-417.
    • (2009) Environment International , vol.35 , pp. 402-417
    • Klavarioti, M.1    Mantzavinos, D.2    Kassinos, D.3
  • 10
    • 4243357294 scopus 로고
    • Photochemical processes for water treatment
    • Legrini, O., Oliveros, E., and Braun, A.M. (1993) Photochemical processes for water treatment. Chemical Reviews, 93, 671-698.
    • (1993) Chemical Reviews , vol.93 , pp. 671-698
    • Legrini, O.1    Oliveros, E.2    Braun, A.M.3
  • 11
    • 68749088604 scopus 로고    scopus 로고
    • Decontamination and disinfection of water by solar photocatalysis: Recent overview and trends
    • Malato, S., Fernández-Ibáñez, P., Maldonado, M.I. et al. (2009) Decontamination and disinfection of water by solar photocatalysis: Recent overview and trends. Catalysis Today, 147, 1-59.
    • (2009) Catalysis Today , vol.147 , pp. 1-59
    • Malato, S.1    Fernández-Ibáñez, P.2    Maldonado, M.I.3
  • 13
    • 84904742287 scopus 로고    scopus 로고
    • Transformation products- relevant risk factors?
    • Fenner, K. (2009) Transformation products- relevant risk factors? Eawag News, 67e, 15-18.
    • (2009) Eawag News , vol.67 e , pp. 15-18
    • Fenner, K.1
  • 14
    • 0002816937 scopus 로고    scopus 로고
    • Factors affecting toxic responses: metabolism
    • ed. J.A. Timbrell), Informa Healthcare, New York, USA
    • Timbrell, J.A. (2008) Factors affecting toxic responses: metabolism, in Principles of Biochemical Toxicology (ed. J.A. Timbrell), Informa Healthcare, New York, USA.
    • (2008) Principles of Biochemical Toxicology
    • Timbrell, J.A.1
  • 15
    • 33846039024 scopus 로고    scopus 로고
    • Environmental risk assessment of antibiotics in the Swedish environment with emphasis on sewage treatment plants
    • Lindberg, R.H., Björklund, K., Rendahl, P. et al. (2007) Environmental risk assessment of antibiotics in the Swedish environment with emphasis on sewage treatment plants. Water Research, 41, 613-619.
    • (2007) Water Research , vol.41 , pp. 613-619
    • Lindberg, R.H.1    Björklund, K.2    Rendahl, P.3
  • 16
    • 67650970074 scopus 로고    scopus 로고
    • On-line solid phase extraction LC- MS/MS analysis of pharmaceutical indicators in water: A green alternative to conventional methods
    • Trenholm, R.A., Vanderford, B.J., and Snyder, S.A. (2009) On-line solid phase extraction LC- MS/MS analysis of pharmaceutical indicators in water: A green alternative to conventional methods. Talanta, 79, 1425-1432.
    • (2009) Talanta , vol.79 , pp. 1425-1432
    • Trenholm, R.A.1    Vanderford, B.J.2    Snyder, S.A.3
  • 18
    • 77958109721 scopus 로고    scopus 로고
    • Pharmaceuticals, personal care products and endocrinedisrupting chemicals in U.S, surface and finished drinking waters: A proposed ranking system
    • Kumar, A. and Xagoraraki, I. (2010) Pharmaceuticals, personal care products and endocrinedisrupting chemicals in U.S. surface and finished drinking waters: A proposed ranking system. The Science of the Total Environment, 408, 5972-5989.
    • (2010) The Science of the Total Environment , vol.408 , pp. 5972-5989
    • Kumar, A.1    Xagoraraki, I.2
  • 19
    • 40349090187 scopus 로고    scopus 로고
    • Occurrence, treatment, and toxicological relevance of EDCs and pharmaceuticals in water
    • Snyder, S.A. (2008) Occurrence, treatment, and toxicological relevance of EDCs and pharmaceuticals in water. Ozone-Science & Engineering, 30, 65-69.
    • (2008) Ozone-Science & Engineering , vol.30 , pp. 65-69
    • Snyder, S.A.1
  • 20
    • 84868697022 scopus 로고    scopus 로고
    • Occurrence and distribution of multi-class pharmaceuticals and their active metabolites and transformation products in the Ebro River basin (NE Spain)
    • López-Serna, R., Petrovíc, M., and Barceló, D. (2012) Occurrence and distribution of multi-class pharmaceuticals and their active metabolites and transformation products in the Ebro River basin (NE Spain). The Science of the Total Environment, 440, 280-289.
    • (2012) The Science of the Total Environment , vol.440 , pp. 280-289
    • López-Serna, R.1    Petrovíc, M.2    Barceló, D.3
  • 21
    • 33846890150 scopus 로고    scopus 로고
    • Occurrence and analysis of pharmaceuticals and their transformation products in drinking water treatment
    • Zwiener, C. (2007) Occurrence and analysis of pharmaceuticals and their transformation products in drinking water treatment. Analytical and Bioanalytical Chemistry, 387, 1159-1162.
    • (2007) Analytical and Bioanalytical Chemistry , vol.387 , pp. 1159-1162
    • Zwiener, C.1
  • 22
    • 73449088388 scopus 로고    scopus 로고
    • Pharmaceutical metabolites in the environment: Analytical challenges and ecological risks
    • Celiz, M.D., Tso, J., and Aga, D.S. (2009) Pharmaceutical metabolites in the environment: Analytical challenges and ecological risks. Environmental Toxicology and Chemistry, 28, 2473-2484.
    • (2009) Environmental Toxicology and Chemistry , vol.28 , pp. 2473-2484
    • Celiz, M.D.1    Tso, J.2    Aga, D.S.3
  • 23
    • 0033383635 scopus 로고    scopus 로고
    • Pharmaceuticals and personal care products in the environment: Agents of subtle change?
    • Daughton, C.G. and Ternes, T.A. (1999) Pharmaceuticals and personal care products in the environment: Agents of subtle change? Environmental Health Perspectives, 107, 907-938.
    • (1999) Environmental Health Perspectives , vol.107 , pp. 907-938
    • Daughton, C.G.1    Ternes, T.A.2
  • 24
    • 3242808156 scopus 로고    scopus 로고
    • Pharmaceuticals in the aquatic environment--a comparison of risk assessment strategies
    • Bound, J.P. and Voulvoulis, N. (2004) Pharmaceuticals in the aquatic environment--a comparison of risk assessment strategies. Chemosphere, 56, 1143-1155.
    • (2004) Chemosphere , vol.56 , pp. 1143-1155
    • Bound, J.P.1    Voulvoulis, N.2
  • 25
    • 0037447779 scopus 로고    scopus 로고
    • Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects
    • Cleuvers, M. (2003) Aquatic ecotoxicity of pharmaceuticals including the assessment of combination effects. Toxicology Letters, 142, 185-194.
    • (2003) Toxicology Letters , vol.142 , pp. 185-194
    • Cleuvers, M.1
  • 27
    • 0032210734 scopus 로고    scopus 로고
    • Occurrence of drugs in German sewage treatment plants and rivers
    • Ternes, T.A. (1998) Occurrence of drugs in German sewage treatment plants and rivers. Water Research, 32, 3245-3260.
    • (1998) Water Research , vol.32 , pp. 3245-3260
    • Ternes, T.A.1
  • 28
    • 42749095770 scopus 로고    scopus 로고
    • The occurrence of acidic drugs and caffeine in sewage effluents and receiving waters from three coastal watersheds in Atlantic Canada
    • Comeau, F., Surette, C., Brun, G.L., and Losier, R. (2008) The occurrence of acidic drugs and caffeine in sewage effluents and receiving waters from three coastal watersheds in Atlantic Canada. The Science of the Total Environment, 396, 132-146.
    • (2008) The Science of the Total Environment , vol.396 , pp. 132-146
    • Comeau, F.1    Surette, C.2    Brun, G.L.3    Losier, R.4
  • 29
    • 42149099355 scopus 로고    scopus 로고
    • Fate of pharmaceutical and trace organic compounds in three septic system plumes, Ontario, Canada
    • Carrara, C., Ptacek, C.J., Robertson, W.D. et al. (2008) Fate of pharmaceutical and trace organic compounds in three septic system plumes, Ontario, Canada. Environmental Science & Technology, 42, 2805-2811.
    • (2008) Environmental Science & Technology , vol.42 , pp. 2805-2811
    • Carrara, C.1    Ptacek, C.J.2    Robertson, W.D.3
  • 30
    • 33646194002 scopus 로고    scopus 로고
    • Determination of acidic drugs and caffeine in municipal wastewaters and receiving waters by gas chromatography-ion trap tandem mass spectrometry
    • Verenitch, S.S., Lowe, C.J., and Mazumder, A. (2006) Determination of acidic drugs and caffeine in municipal wastewaters and receiving waters by gas chromatography-ion trap tandem mass spectrometry. Journal of Chromatography A, 1116, 193-203.
    • (2006) Journal of Chromatography A , vol.1116 , pp. 193-203
    • Verenitch, S.S.1    Lowe, C.J.2    Mazumder, A.3
  • 31
    • 27344432627 scopus 로고    scopus 로고
    • Determination of endocrine-disrupting phenols, acidic pharmaceuticals, and personal-care products in sewage by solid-phase extraction and gas chromatography-mass spectrometry
    • Lee, H., Peart, T.E., and Svoboda, M.L. (2005) Determination of endocrine-disrupting phenols, acidic pharmaceuticals, and personal-care products in sewage by solid-phase extraction and gas chromatography-mass spectrometry. Journal of Chromatography A, 1094, 122-129.
    • (2005) Journal of Chromatography A , vol.1094 , pp. 122-129
    • Lee, H.1    Peart, T.E.2    Svoboda, M.L.3
  • 32
    • 49049118296 scopus 로고    scopus 로고
    • Determination of basic antidepressants and their N-Desmethyl metabolites in raw sewage and wastewater using solid-phase extraction and liquid chromatography-tandem mass spectrometry
    • Lajeunesse, A., Gagnon, C., and Sauve, S. (2008) Determination of basic antidepressants and their N-Desmethyl metabolites in raw sewage and wastewater using solid-phase extraction and liquid chromatography-tandem mass spectrometry. Analytical Chemistry, 80, 5325-5333.
    • (2008) Analytical Chemistry , vol.80 , pp. 5325-5333
    • Lajeunesse, A.1    Gagnon, C.2    Sauve, S.3
  • 34
    • 79951496270 scopus 로고    scopus 로고
    • Input of selected human pharmaceutical metabolites into the Norwegian aquatic environment
    • Langford, K. and Thomas, K.V. (2011) Input of selected human pharmaceutical metabolites into the Norwegian aquatic environment. Journal of Environmental Monitoring, 13, 416-421.
    • (2011) Journal of Environmental Monitoring , vol.13 , pp. 416-421
    • Langford, K.1    Thomas, K.V.2
  • 35
    • 0042062423 scopus 로고    scopus 로고
    • Determination of carbamazepine and its metabolites in aqueous samples using liquid chromatography-electrospray tandem mass spectrometry
    • Miao, X. and Metcalfe, C.D. (2003) Determination of carbamazepine and its metabolites in aqueous samples using liquid chromatography-electrospray tandem mass spectrometry. Analytical Chemistry, 75, 3731-3738.
    • (2003) Analytical Chemistry , vol.75 , pp. 3731-3738
    • Miao, X.1    Metcalfe, C.D.2
  • 36
    • 26044433775 scopus 로고    scopus 로고
    • Carbamazepine and its metabolites in wastewater and in biosolids in a municipal wastewater treatment plant
    • Miao, X., Yang, J., and Metcalfe, C.D. (2005) Carbamazepine and its metabolites in wastewater and in biosolids in a municipal wastewater treatment plant. Environmental Science & Technology, 39, 7469-7475.
    • (2005) Environmental Science & Technology , vol.39 , pp. 7469-7475
    • Miao, X.1    Yang, J.2    Metcalfe, C.D.3
  • 37
    • 84861186616 scopus 로고    scopus 로고
    • Screening and human health risk assessment of pharmaceuticals and their transformation products in Dutch surface waters and drinking water
    • De Jongh, C.M., Kooij, P.J.F., de Voogt, P., and ter Laak, T.L. (2012) Screening and human health risk assessment of pharmaceuticals and their transformation products in Dutch surface waters and drinking water. The Science of the Total Environment, 427-428, 70-77.
    • (2012) The Science of the Total Environment , vol.427-428 , pp. 70-77
    • De Jongh, C.M.1    Kooij, P.J.F.2    de Voogt, P.3    Ter Laak, T.L.4
  • 38
    • 41449100984 scopus 로고    scopus 로고
    • Characterizing and compensating for matrix effects using atmospheric pressure chemical ionization liquid chromatography-tandem mass spectrometry: Analysis of neutral pharmaceuticals in municipal wastewater
    • Zhao, X. and Metcalfe, C.D. (2008) Characterizing and compensating for matrix effects using atmospheric pressure chemical ionization liquid chromatography-tandem mass spectrometry: Analysis of neutral pharmaceuticals in municipal wastewater. Analytical Chemistry, 80, 2010-2017.
    • (2008) Analytical Chemistry , vol.80 , pp. 2010-2017
    • Zhao, X.1    Metcalfe, C.D.2
  • 39
    • 0242432390 scopus 로고    scopus 로고
    • Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry
    • Koutsouba, V., Heberer, T., Fuhrmann, B. et al. (2003) Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry. Chemosphere, 51, 69-75.
    • (2003) Chemosphere , vol.51 , pp. 69-75
    • Koutsouba, V.1    Heberer, T.2    Fuhrmann, B.3
  • 40
    • 0242525758 scopus 로고    scopus 로고
    • Multi-compound methods for the detection of pharmaceutical residues in various waters applying solid phase extraction (SPE) and gas chromatography with mass spectrometric (GC-MS) detection
    • Reddersen, K. and Heberer, T. (2003) Multi-compound methods for the detection of pharmaceutical residues in various waters applying solid phase extraction (SPE) and gas chromatography with mass spectrometric (GC-MS) detection. Journal of Separation Science, 26, 1443-1450.
    • (2003) Journal of Separation Science , vol.26 , pp. 1443-1450
    • Reddersen, K.1    Heberer, T.2
  • 41
    • 25844491008 scopus 로고    scopus 로고
    • A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewaters
    • Castiglioni, S., Bagnati, R., Calamari, D. et al. (2005) A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewaters. Journal of Chromatography A, 1092, 206-215.
    • (2005) Journal of Chromatography A , vol.1092 , pp. 206-215
    • Castiglioni, S.1    Bagnati, R.2    Calamari, D.3
  • 42
    • 0141792748 scopus 로고    scopus 로고
    • Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry
    • Hilton, M. and Thomas, K. (2003) Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography A, 1015, 129-141.
    • (2003) Journal of Chromatography A , vol.1015 , pp. 129-141
    • Hilton, M.1    Thomas, K.2
  • 43
    • 67650103429 scopus 로고    scopus 로고
    • Evaluation of various liquid chromatography- quadrupole-linear ion trap-mass spectrometry operation modes applied to the analysis of organic pollutants in wastewaters
    • Bueno, M.J.M., Agüera, A., Hernando, M.D. et al. (2009) Evaluation of various liquid chromatography- quadrupole-linear ion trap-mass spectrometry operation modes applied to the analysis of organic pollutants in wastewaters. Journal of ChromatographyA, 1216, 5995-6002.
    • (2009) Journal of ChromatographyA , vol.1216 , pp. 5995-6002
    • Bueno, M.J.M.1    Agüera, A.2    Hernando, M.D.3
  • 44
    • 67649397391 scopus 로고    scopus 로고
    • Removal of pharmaceuticals in secondary wastewater treatment processes in Taiwan
    • Lin, A.Y., Yu, T., and Lateef, S.K. (2009) Removal of pharmaceuticals in secondary wastewater treatment processes in Taiwan. Journal of Hazardous Materials, 167, 1163-1169.
    • (2009) Journal of Hazardous Materials , vol.167 , pp. 1163-1169
    • Lin, A.Y.1    Yu, T.2    Lateef, S.K.3
  • 45
    • 2942718830 scopus 로고    scopus 로고
    • Determination of selected pharmaceuticals and caffeine in sewage and seawater from Tromsø/Norway with emphasis on ibuprofen and its metabolites
    • Weigel, S., Berger, U., Jensen, E. et al. (2004) Determination of selected pharmaceuticals and caffeine in sewage and seawater from Tromsø/Norway with emphasis on ibuprofen and its metabolites. Chemosphere, 56, 583-592.
    • (2004) Chemosphere , vol.56 , pp. 583-592
    • Weigel, S.1    Berger, U.2    Jensen, E.3
  • 47
    • 32644485467 scopus 로고    scopus 로고
    • The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment
    • Roberts, P.H. and Thomas, K.V. (2006) The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment. The Science of the Total Environment, 356, 143-153.
    • (2006) The Science of the Total Environment , vol.356 , pp. 143-153
    • Roberts, P.H.1    Thomas, K.V.2
  • 48
    • 30644479441 scopus 로고    scopus 로고
    • Ecotoxicology of human pharmaceuticals
    • Fent, K., Weston, A.A., and Caminada, D. (2006) Ecotoxicology of human pharmaceuticals. Aquatic Toxicology, 76, 122-159.
    • (2006) Aquatic Toxicology , vol.76 , pp. 122-159
    • Fent, K.1    Weston, A.A.2    Caminada, D.3
  • 49
    • 77958186830 scopus 로고    scopus 로고
    • Illicit drugs in Canadian municipal wastewater and estimates of community drug use
    • Metcalfe, C., Tindale, K., Li, H. et al. (2010) Illicit drugs in Canadian municipal wastewater and estimates of community drug use. Environmental Pollution, 158, 3179-3185.
    • (2010) Environmental Pollution , vol.158 , pp. 3179-3185
    • Metcalfe, C.1    Tindale, K.2    Li, H.3
  • 50
    • 35348977720 scopus 로고    scopus 로고
    • Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China
    • Xu, W., Zhang, G., Li, X. et al. (2007) Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China. Water Research, 41, 4526-4534.
    • (2007) Water Research , vol.41 , pp. 4526-4534
    • Xu, W.1    Zhang, G.2    Li, X.3
  • 51
    • 34447626834 scopus 로고    scopus 로고
    • The occurrence of selected antibiotics in Hong Kong coastal waters
    • Gulkowska, A., He, Y., So, M.K. et al. (2007) The occurrence of selected antibiotics in Hong Kong coastal waters. Marine Pollution Bulletin, 54, 1287-1293.
    • (2007) Marine Pollution Bulletin , vol.54 , pp. 1287-1293
    • Gulkowska, A.1    He, Y.2    So, M.K.3
  • 52
    • 67349280348 scopus 로고    scopus 로고
    • Occurrence of pharmaceuticals in Taiwan's surface waters: Impact of waste streams from hospitals and pharmaceutical production facilities
    • Lin, A.Y. and Tsai, Y. (2009) Occurrence of pharmaceuticals in Taiwan's surface waters: Impact of waste streams from hospitals and pharmaceutical production facilities. The Science of the Total Environment, 407, 3793-3802.
    • (2009) The Science of the Total Environment , vol.407 , pp. 3793-3802
    • Lin, A.Y.1    Tsai, Y.2
  • 53
    • 69949182842 scopus 로고    scopus 로고
    • Depletion of selective serotonin reuptake inhibitors during sewage sludge composting
    • Vasskog, T., Bergersen, O., Anderssen, T. et al. (2009) Depletion of selective serotonin reuptake inhibitors during sewage sludge composting. Waste Management, 29, 2808-2815.
    • (2009) Waste Management , vol.29 , pp. 2808-2815
    • Vasskog, T.1    Bergersen, O.2    Anderssen, T.3
  • 54
    • 20444435797 scopus 로고    scopus 로고
    • Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden
    • Bendz, D., Paxéus, N.A., Ginn, T.R., and Loge, F.J. (2005) Occurrence and fate of pharmaceutically active compounds in the environment, a case study: Höje River in Sweden. Journal of Hazardous Materials, 122, 195-204.
    • (2005) Journal of Hazardous Materials , vol.122 , pp. 195-204
    • Bendz, D.1    Paxéus, N.A.2    Ginn, T.R.3    Loge, F.J.4
  • 55
    • 0000039914 scopus 로고    scopus 로고
    • Isolierung von ibuprofenmetaboliten und deren bedeutung als kontaminanten der aquatischen umwelt
    • Stumpf, M., Ternes, T.A., Haberer, K., and Baumann, W. (1998) Isolierung von ibuprofenmetaboliten und deren bedeutung als kontaminanten der aquatischen umwelt. Vom Wasser, 91, 291-303.
    • (1998) Vom Wasser , vol.91 , pp. 291-303
    • Stumpf, M.1    Ternes, T.A.2    Haberer, K.3    Baumann, W.4
  • 56
    • 60849115540 scopus 로고    scopus 로고
    • Monitoring of opiates, cannabinoids and their metabolites in wastewater, surface water and finished water in Catalonia, Spain
    • Boleda, M.R., Galceran, M.T., and Ventura, F. (2009) Monitoring of opiates, cannabinoids and their metabolites in wastewater, surface water and finished water in Catalonia, Spain. Water Research, 43, 1126-1136.
    • (2009) Water Research , vol.43 , pp. 1126-1136
    • Boleda, M.R.1    Galceran, M.T.2    Ventura, F.3
  • 57
    • 78249286535 scopus 로고    scopus 로고
    • Occurrence and fate of the human pharmaceutical metabolite ritalinic acid in the aquatic system
    • Letzel, M., Weiss, K., Schüssler, W., and Sengl, M. (2010) Occurrence and fate of the human pharmaceutical metabolite ritalinic acid in the aquatic system. Chemosphere, 81, 1416-1422.
    • (2010) Chemosphere , vol.81 , pp. 1416-1422
    • Letzel, M.1    Weiss, K.2    Schüssler, W.3    Sengl, M.4
  • 58
    • 0036837216 scopus 로고    scopus 로고
    • Identification and significance of phenazone drugs and their metabolites in ground- and drinking water
    • Reddersen, K., Heberer, T., and Dünnbier, U. (2002) Identification and significance of phenazone drugs and their metabolites in ground- and drinking water. Chemosphere, 49, 539-544.
    • (2002) Chemosphere , vol.49 , pp. 539-544
    • Reddersen, K.1    Heberer, T.2    Dünnbier, U.3
  • 59
    • 20044394550 scopus 로고    scopus 로고
    • Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment
    • Göbel, A., Thomsen, A., McArdell, C.S. et al. (2005) Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment. Environmental Science & Technology, 39, 3981-3989.
    • (2005) Environmental Science & Technology , vol.39 , pp. 3981-3989
    • Göbel, A.1    Thomsen, A.2    McArdell, C.S.3
  • 60
    • 84856330540 scopus 로고    scopus 로고
    • Determination of six sulfonamide antibiotics, two metabolites and trimethoprim in wastewater by isotope dilution liquid chromatography/tandem mass spectrometry
    • Le-Minh, N., Stuetz, R.M., and Khan, S.J. (2012) Determination of six sulfonamide antibiotics, two metabolites and trimethoprim in wastewater by isotope dilution liquid chromatography/tandem mass spectrometry. Talanta, 89, 407-416.
    • (2012) Talanta , vol.89 , pp. 407-416
    • Le-Minh, N.1    Stuetz, R.M.2    Khan, S.J.3
  • 61
    • 0035809816 scopus 로고    scopus 로고
    • Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection
    • Zaugg, S., Zhang, X., Sweedler, J., and Thormann, W. (2001) Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection. Journal of Chromatography B, 752, 17-31.
    • (2001) Journal of Chromatography B , vol.752 , pp. 17-31
    • Zaugg, S.1    Zhang, X.2    Sweedler, J.3    Thormann, W.4
  • 63
    • 7044220553 scopus 로고    scopus 로고
    • Life-history traits of standard and autochthonous cladocerans: I, Acute and chronic effects of acetylsalicylic acid
    • Marques, C.R., Abrantes, N., and GonScalves, F. (2004) Life-history traits of standard and autochthonous cladocerans: I. Acute and chronic effects of acetylsalicylic acid. Environmental Toxicology, 19, 518-526.
    • (2004) Environmental Toxicology , vol.19 , pp. 518-526
    • Marques, C.R.1    Abrantes, N.2    GonScalves, F.3
  • 64
    • 0032912536 scopus 로고    scopus 로고
    • Detection of 2-Hydroxyiminostilbene in the urine of patients taking carbamazepine and its oxidation to a reactive iminoquinone intermediate
    • Ju, C. and Uetrecht, J.P. (1999) Detection of 2-Hydroxyiminostilbene in the urine of patients taking carbamazepine and its oxidation to a reactive iminoquinone intermediate. The Journal of Pharmacology and Experimental Therapeutics, 288, 51-56.
    • (1999) The Journal of Pharmacology and Experimental Therapeutics , vol.288 , pp. 51-56
    • Ju, C.1    Uetrecht, J.P.2
  • 65
    • 35548939330 scopus 로고    scopus 로고
    • Evaluation of the in vitro biotransformation of fluoxetine with HPLC, mass spectrometry and ecotoxicological tests
    • Nalečz-Jawecki, G. (2007) Evaluation of the in vitro biotransformation of fluoxetine with HPLC, mass spectrometry and ecotoxicological tests. Chemosphere, 70, 29-35.
    • (2007) Chemosphere , vol.70 , pp. 29-35
    • Nalečz-Jawecki, G.1
  • 66
    • 23744512414 scopus 로고    scopus 로고
    • Removal of pharmaceuticals and fragrances in biological wastewater treatment
    • Joss, A., Keller, E., Alder, A.C. et al. (2005) Removal of pharmaceuticals and fragrances in biological wastewater treatment. Water Research, 39, 3139-3152.
    • (2005) Water Research , vol.39 , pp. 3139-3152
    • Joss, A.1    Keller, E.2    Alder, A.C.3
  • 67
    • 33845937762 scopus 로고    scopus 로고
    • Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies
    • Göbel, A., McArdell, C.S., Joss, A. et al. (2007) Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies. The Science of the Total Environment, 372, 361-371.
    • (2007) The Science of the Total Environment , vol.372 , pp. 361-371
    • Göbel, A.1    McArdell, C.S.2    Joss, A.3
  • 68
    • 13844319935 scopus 로고    scopus 로고
    • Drug bioactivation covalent binding to target proteins and toxicity relevance
    • Zhou, S., Chan, E., Duan, W. et al. (2005) Drug bioactivation covalent binding to target proteins and toxicity relevance. Drug Metabolism Reviews, 37, 41-213.
    • (2005) Drug Metabolism Reviews , vol.37 , pp. 41-213
    • Zhou, S.1    Chan, E.2    Duan, W.3
  • 69
    • 34249980891 scopus 로고    scopus 로고
    • Application of advanced MS techniques to analysis and identification of human and microbial metabolites of pharmaceuticals in the aquatic environment
    • Pérez, S. and Barceló, D. (2007) Application of advanced MS techniques to analysis and identification of human and microbial metabolites of pharmaceuticals in the aquatic environment. TrAC Trends in Analytical Chemistry, 26, 494-514.
    • (2007) TrAC Trends in Analytical Chemistry , vol.26 , pp. 494-514
    • Pérez, S.1    Barceló, D.2
  • 70
    • 3042569762 scopus 로고    scopus 로고
    • Environmental risk assessment of medicinal products for human use according to european commission recommendations
    • Huschek, G., Hansen, P.D., Maurer, H.H. et al. (2004) Environmental risk assessment of medicinal products for human use according to european commission recommendations. Environmental Toxicology, 19, 226-240.
    • (2004) Environmental Toxicology , vol.19 , pp. 226-240
    • Huschek, G.1    Hansen, P.D.2    Maurer, H.H.3
  • 71
    • 56449083885 scopus 로고    scopus 로고
    • Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment
    • Farré, M.l., Pérez, S., Kantiani, L., and Barceló, D. (2008) Fate and toxicity of emerging pollutants, their metabolites and transformation products in the aquatic environment. TrAC Trends in Analytical Chemistry, 27, 991-1007.
    • (2008) TrAC Trends in Analytical Chemistry , vol.27 , pp. 991-1007
    • Farré, M.l.1    Pérez, S.2    Kantiani, L.3    Barceló, D.4
  • 73
    • 0033016288 scopus 로고    scopus 로고
    • Behaviour and occurrence of estrogens in municipal sewage treatment plants-II, Aerobic batch experiments with activated sludge
    • Ternes, T.A., Kreckel, P., and Mueller, J. (1999) Behaviour and occurrence of estrogens in municipal sewage treatment plants-II. Aerobic batch experiments with activated sludge. The Science of the Total Environment, 225, 91-99.
    • (1999) The Science of the Total Environment , vol.225 , pp. 91-99
    • Ternes, T.A.1    Kreckel, P.2    Mueller, J.3
  • 74
    • 3042521214 scopus 로고    scopus 로고
    • Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant
    • Carballa, M., Omil, F., Lema, J.M. et al. (2004) Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant. Water Research, 38, 2918-2926.
    • (2004) Water Research , vol.38 , pp. 2918-2926
    • Carballa, M.1    Omil, F.2    Lema, J.M.3
  • 75
    • 79953235345 scopus 로고    scopus 로고
    • Biotransformation of the antiviral drugs acyclovir and penciclovir in activated sludge treatment
    • Prasse, C., Wagner, M., Schulz, R., and Ternes, T. (2011) Biotransformation of the antiviral drugs acyclovir and penciclovir in activated sludge treatment. Environmental Science & Technology, 45, 2761-2769.
    • (2011) Environmental Science & Technology , vol.45 , pp. 2761-2769
    • Prasse, C.1    Wagner, M.2    Schulz, R.3    Ternes, T.4
  • 76
    • 54349095319 scopus 로고    scopus 로고
    • Identification and structural characterization of biodegradation products of atenolol and glibenclamide by liquid chromatography coupled to hybrid quadrupole time-of-flight and quadrupole ion trap mass spectrometry
    • Radjenovíc, J., Pérez, S., Petrovíc, M., and Barceló, D. (2008) Identification and structural characterization of biodegradation products of atenolol and glibenclamide by liquid chromatography coupled to hybrid quadrupole time-of-flight and quadrupole ion trap mass spectrometry. Journal of Chromatography A, 1210, 142-153.
    • (2008) Journal of Chromatography A , vol.1210 , pp. 142-153
    • Radjenovíc, J.1    Pérez, S.2    Petrovíc, M.3    Barceló, D.4
  • 77
    • 79960556820 scopus 로고    scopus 로고
    • Identification of biotransformation products of macrolide and fluoroquinolone antimicrobials in membrane bioreactor treatment by ultrahigh- performance liquid chromatography/quadrupole time-of-flight mass spectrometry
    • Terzic, S., Senta, I., Matosic, M., and Ahel, M. (2011) Identification of biotransformation products of macrolide and fluoroquinolone antimicrobials in membrane bioreactor treatment by ultrahigh- performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Analytical and Bioanalytical Chemistry, 401(1), 353-363.
    • (2011) Analytical and Bioanalytical Chemistry , vol.401 , Issue.1 , pp. 353-363
    • Terzic, S.1    Senta, I.2    Matosic, M.3    Ahel, M.4
  • 78
    • 21744460381 scopus 로고    scopus 로고
    • Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor
    • Quintana, J.B., Weiss, S., and Reemtsma, T. (2005) Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor. Water Research, 39, 2654-2664.
    • (2005) Water Research , vol.39 , pp. 2654-2664
    • Quintana, J.B.1    Weiss, S.2    Reemtsma, T.3
  • 79
    • 80555126786 scopus 로고    scopus 로고
    • Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea
    • Trautwain, C., Kümmerer, K. (2012) Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea. Chemosphere, 85(5), 765-773.
    • (2012) Chemosphere , vol.85 , Issue.5 , pp. 765-773
    • Trautwain, C.1    Kümmerer, K.2
  • 80
    • 58549086167 scopus 로고    scopus 로고
    • Acetylation of fluoroquinolone antimicrobial agents by an Escherichia coli strain isolated from a municipal wastewater treatment plant
    • Jung, C.M., Heinze, T.M., Strakosha, R., Elkins, C.A., and Sutherland, J.B. (2009) Acetylation of fluoroquinolone antimicrobial agents by an Escherichia coli strain isolated from a municipal wastewater treatment plant. Journal of Applied Microbiology, 106(2), 564-571.
    • (2009) Journal of Applied Microbiology , vol.106 , Issue.2 , pp. 564-571
    • Jung, C.M.1    Heinze, T.M.2    Strakosha, R.3    Elkins, C.A.4    Sutherland, J.B.5
  • 81
    • 28444493966 scopus 로고    scopus 로고
    • Biodegradability of the X-ray contrast compound diatrizoic acid, identification of aerobic degradation products and effects against sewage sludge microorganisms
    • Haí, A., and Kümmerer, K. (2006) Biodegradability of the X-ray contrast compound diatrizoic acid, identification of aerobic degradation products and effects against sewage sludge microorganisms. Chemosphere, 62(2), 294-302.
    • (2006) Chemosphere , vol.62 , Issue.2 , pp. 294-302
    • Haí, A.1    Kümmerer, K.2
  • 82
    • 0033052766 scopus 로고    scopus 로고
    • Biodegradation of the iodinated X-ray contrast media diatrizoate and iopromide
    • Kalsch, W. (1999) Biodegradation of the iodinated X-ray contrast media diatrizoate and iopromide. The Science of the Total Environment, 225(1-2), 143-153.
    • (1999) The Science of the Total Environment , vol.225 , Issue.1-2 , pp. 143-153
    • Kalsch, W.1
  • 83
    • 34548250986 scopus 로고    scopus 로고
    • Transformation of diclofenac by the indigenous microflora of river sediments and identification of a major intermediate
    • Gröning, J., Held, C., Garten, C. et al. (2007) Transformation of diclofenac by the indigenous microflora of river sediments and identification of a major intermediate. Chemosphere, 69, 509-516.
    • (2007) Chemosphere , vol.69 , pp. 509-516
    • Gröning, J.1    Held, C.2    Garten, C.3
  • 84
    • 33846862877 scopus 로고    scopus 로고
    • Removal of pharmaceutical residues in a pilot wastewater treatment plant
    • Kosjek, T., Heath, E., and Kompare, B. (2007) Removal of pharmaceutical residues in a pilot wastewater treatment plant. Analytical and Bioanalytical Chemistry, 387, 1379-1387.
    • (2007) Analytical and Bioanalytical Chemistry , vol.387 , pp. 1379-1387
    • Kosjek, T.1    Heath, E.2    Kompare, B.3
  • 85
    • 35448954016 scopus 로고    scopus 로고
    • Investigation of the behavior and metabolism of pharmaceutical residues during purification of contaminated ground water used for drinking water supply
    • Zuehlke, S., Duennbier, U., and Heberer, T. (2007) Investigation of the behavior and metabolism of pharmaceutical residues during purification of contaminated ground water used for drinking water supply. Chemosphere, 69, 1673-1680.
    • (2007) Chemosphere , vol.69 , pp. 1673-1680
    • Zuehlke, S.1    Duennbier, U.2    Heberer, T.3
  • 86
    • 0036244798 scopus 로고    scopus 로고
    • Metabolites from the biodegradation of pharmaceutical residues of ibuprofen in biofilm reactors and batch experiments
    • Zwiener, C.Z., Seeger, S.S., Glauner, T.G., and Frimmel, F.F. (2002) Metabolites from the biodegradation of pharmaceutical residues of ibuprofen in biofilm reactors and batch experiments. Journal of Analytical and Bioanalytical Chemistry, 372, 569-575.
    • (2002) Journal of Analytical and Bioanalytical Chemistry , vol.372 , pp. 569-575
    • Zwiener, C.Z.1    Seeger, S.S.2    Glauner, T.G.3    Frimmel, F.F.4
  • 87
    • 0034912325 scopus 로고    scopus 로고
    • Selective degradation of ibuprofen and clofibric acid in two model river biofilm systems
    • Winkler, M., Lawrence, J.R., and Neu, T.R. (2001) Selective degradation of ibuprofen and clofibric acid in two model river biofilm systems. Water Research, 35, 3197-3205.
    • (2001) Water Research , vol.35 , pp. 3197-3205
    • Winkler, M.1    Lawrence, J.R.2    Neu, T.R.3
  • 88
    • 40249112985 scopus 로고    scopus 로고
    • Behaviour of pharmaceutical products and biodegradation intermediates in horizontal subsurface flow constructed wetland. A microcosm experiment
    • Matamoros, V., Caselles-Osorio, A., García, J., and Bayona, J.M. (2008) Behaviour of pharmaceutical products and biodegradation intermediates in horizontal subsurface flow constructed wetland. A microcosm experiment. The Science of the Total Environment, 394, 171-176.
    • (2008) The Science of the Total Environment , vol.394 , pp. 171-176
    • Matamoros, V.1    Caselles-Osorio, A.2    García, J.3    Bayona, J.M.4
  • 89
    • 58549115673 scopus 로고    scopus 로고
    • Ability of white-rot fungi to remove selected pharmaceuticals and identification of degradation products of ibuprofen by Trametes versicolor
    • Marco-Urrea, E., Pérez-Trujillo, M., Vicent, T., and Caminal, G. (2009) Ability of white-rot fungi to remove selected pharmaceuticals and identification of degradation products of ibuprofen by Trametes versicolor. Chemosphere, 74, 765-772.
    • (2009) Chemosphere , vol.74 , pp. 765-772
    • Marco-Urrea, E.1    Pérez-Trujillo, M.2    Vicent, T.3    Caminal, G.4
  • 90
    • 33645213334 scopus 로고    scopus 로고
    • Structural characterization of metabolites of the X-ray contrast agent Iopromide in activated sludge using Ion Trap Mass Spectrometry
    • Perez, S., Eichhorn, P., Celiz, M.D., and Aga, D.S. (2006) Structural characterization of metabolites of the X-ray contrast agent Iopromide in activated sludge using Ion Trap Mass Spectrometry. Analytical Chemistry, 78, 1866-1874.
    • (2006) Analytical Chemistry , vol.78 , pp. 1866-1874
    • Perez, S.1    Eichhorn, P.2    Celiz, M.D.3    Aga, D.S.4
  • 91
    • 0036027486 scopus 로고    scopus 로고
    • Investigations into the environmental fate and effects of iopromide (ultravist), a widely used iodinated X-ray contrast medium
    • Steger-Hartmann, T., Länge, R., Schweinfurth, H. et al. (2002) Investigations into the environmental fate and effects of iopromide (ultravist), a widely used iodinated X-ray contrast medium. Water Research, 36, 266-274.
    • (2002) Water Research , vol.36 , pp. 266-274
    • Steger-Hartmann, T.1    Länge, R.2    Schweinfurth, H.3
  • 92
    • 84864033662 scopus 로고    scopus 로고
    • Occurrence and fate of the antidiabetic drug metformin and its metabolite guanylurea in the environment and during drinking water treatment
    • Scheurer, M., Michel, A., Brauch, H. et al. (2012) Occurrence and fate of the antidiabetic drug metformin and its metabolite guanylurea in the environment and during drinking water treatment. Water Research, 46, 4790-4802.
    • (2012) Water Research , vol.46 , pp. 4790-4802
    • Scheurer, M.1    Michel, A.2    Brauch, H.3
  • 93
    • 80555126786 scopus 로고    scopus 로고
    • Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea
    • Trautwein, C. and Kümmerer, K. (2011) Incomplete aerobic degradation of the antidiabetic drug Metformin and identification of the bacterial dead-end transformation product Guanylurea. Chemosphere, 85, 765-773.
    • (2011) Chemosphere , vol.85 , pp. 765-773
    • Trautwein, C.1    Kümmerer, K.2
  • 94
    • 0038370106 scopus 로고    scopus 로고
    • Microbial transformation of naproxen by Cunninghamella species
    • Zhong, D., Sun, L., Liu, L., and Huang, H. (2003) Microbial transformation of naproxen by Cunninghamella species. Acta Pharmacologica Sinica, 24, 442-447.
    • (2003) Acta Pharmacologica Sinica , vol.24 , pp. 442-447
    • Zhong, D.1    Sun, L.2    Liu, L.3    Huang, H.4
  • 96
    • 80054717380 scopus 로고    scopus 로고
    • Biodegradation of sulfamethazine by Trametes versicolor: Removal from sewage sludge and identification of intermediate products by UPLC-QqTOF-MS
    • García-Galán, M.J., Rodríguez-Rodríguez, C.E., Vicent, T. et al. (2011) Biodegradation of sulfamethazine by Trametes versicolor: Removal from sewage sludge and identification of intermediate products by UPLC-QqTOF-MS. The Science of the Total Environment, 409, 5505-5512.
    • (2011) The Science of the Total Environment , vol.409 , pp. 5505-5512
    • García-Galán, M.J.1    Rodríguez-Rodríguez, C.E.2    Vicent, T.3
  • 97
    • 77952967174 scopus 로고    scopus 로고
    • Biodegradation of pharmaceuticals by Rhodococcus rhodochrous and Aspergillus niger by co-metabolism
    • Gauthier, H., Yargeau, V., and Cooper, D.G. (2010) Biodegradation of pharmaceuticals by Rhodococcus rhodochrous and Aspergillus niger by co-metabolism. The Science of the Total Environment, 408, 1701-1706.
    • (2010) The Science of the Total Environment , vol.408 , pp. 1701-1706
    • Gauthier, H.1    Yargeau, V.2    Cooper, D.G.3
  • 98
    • 21644470525 scopus 로고    scopus 로고
    • Application of Ion Trap-MS with H/D exchange and QqTOF-MS in the identification of microbial degradates of trimethoprim in nitrifying activated sludge
    • Eichhorn, P., Ferguson, P.L., Perez, S., and Aga, D.S. (2005) Application of Ion Trap-MS with H/D exchange and QqTOF-MS in the identification of microbial degradates of trimethoprim in nitrifying activated sludge. Analytical Chemistry, 77, 4176-4184.
    • (2005) Analytical Chemistry , vol.77 , pp. 4176-4184
    • Eichhorn, P.1    Ferguson, P.L.2    Perez, S.3    Aga, D.S.4
  • 99
    • 84857426971 scopus 로고    scopus 로고
    • Electron density-based transformation of trimethoprim during biological wastewater treatment
    • Yi, T., Barr, W., and Harper, W.F. (2012) Electron density-based transformation of trimethoprim during biological wastewater treatment. Water Science and Technology, 65(4), 689-696.
    • (2012) Water Science and Technology , vol.65 , Issue.4 , pp. 689-696
    • Yi, T.1    Barr, W.2    Harper, W.F.3
  • 100
    • 43649091385 scopus 로고    scopus 로고
    • Aerobic biodegradability of the calcium channel antagonist verapamil and identification of a microbial dead-end transformation product studied by LC-MS/MS
    • Trautwein, C., Kümmerer, K., and Metzger, J.W. (2008) Aerobic biodegradability of the calcium channel antagonist verapamil and identification of a microbial dead-end transformation product studied by LC-MS/MS. Chemosphere, 72(3), 442-450.
    • (2008) Chemosphere , vol.72 , Issue.3 , pp. 442-450
    • Trautwein, C.1    Kümmerer, K.2    Metzger, J.W.3
  • 101
    • 0033178848 scopus 로고    scopus 로고
    • Occurrence and environmental behavior of the chiral pharmaceutical drug ibuprofen in surface waters and in wastewater
    • Buser, H., Poiger, T., and Muller, M.D. (1999) Occurrence and environmental behavior of the chiral pharmaceutical drug ibuprofen in surface waters and in wastewater. Environmental Science & Technology, 33, 2529-2535.
    • (1999) Environmental Science & Technology , vol.33 , pp. 2529-2535
    • Buser, H.1    Poiger, T.2    Muller, M.D.3
  • 102
    • 22344441047 scopus 로고    scopus 로고
    • Behavior of selected pharmaceuticals in subsurface flow constructed wetlands: A pilot-scale study
    • Matamoros, V., García, J., and Bayona, J.M. (2005) Behavior of selected pharmaceuticals in subsurface flow constructed wetlands: A pilot-scale study. Environmental Science & Technology, 39, 5449-5454.
    • (2005) Environmental Science & Technology , vol.39 , pp. 5449-5454
    • Matamoros, V.1    García, J.2    Bayona, J.M.3
  • 103
    • 77954265382 scopus 로고    scopus 로고
    • Biotransformation of selected iodinated X-ray contrast media and characterization of microbial transformation Pathways
    • Kormos, J.L., Schulz, M., Kohler, H.E., and Ternes, T.A. (2010) Biotransformation of selected iodinated X-ray contrast media and characterization of microbial transformation Pathways. Environmental Science & Technology, 44, 4998-5007.
    • (2010) Environmental Science & Technology , vol.44 , pp. 4998-5007
    • Kormos, J.L.1    Schulz, M.2    Kohler, H.E.3    Ternes, T.A.4
  • 104
    • 33645213334 scopus 로고    scopus 로고
    • Structural characterization of metabolites of the X-ray contrast agent Iopromide in activated sludge using ion trap mass spectrometry
    • Pérez, S., Eichhorn, P., Celiz, M.D., and Aga, D.S. (2006) Structural characterization of metabolites of the X-ray contrast agent Iopromide in activated sludge using ion trap mass spectrometry. Analytical Chemistry, 78, 1866-1874.
    • (2006) Analytical Chemistry , vol.78 , pp. 1866-1874
    • Pérez, S.1    Eichhorn, P.2    Celiz, M.D.3    Aga, D.S.4
  • 105
    • 54349095319 scopus 로고    scopus 로고
    • Identification and structural characterization of biodegradation products of atenolol and glibenclamide by liquid chromatography coupled to hybrid quadrupole time-of-flight and quadrupole ion trap mass spectrometry
    • Radjenovíc, J., Pérez, S., Petrovíc, M., and Barceló, D. (2008) Identification and structural characterization of biodegradation products of atenolol and glibenclamide by liquid chromatography coupled to hybrid quadrupole time-of-flight and quadrupole ion trap mass spectrometry. Journal of Chromatography A, 1210(2), 142-153.
    • (2008) Journal of Chromatography A , vol.1210 , Issue.2 , pp. 142-153
    • Radjenovíc, J.1    Pérez, S.2    Petrovíc, M.3    Barceló, D.4
  • 106
    • 79954557582 scopus 로고    scopus 로고
    • Elucidation of the transformation pathway of the opium alkaloid codeine in biological wastewater treatment
    • Wick, A., Wagner, M., and Ternes, T.A. (2011) Elucidation of the transformation pathway of the opium alkaloid codeine in biological wastewater treatment. Environmental Science & Technology, 45, 3374-3385.
    • (2011) Environmental Science & Technology , vol.45 , pp. 3374-3385
    • Wick, A.1    Wagner, M.2    Ternes, T.A.3
  • 107
    • 84958224979 scopus 로고    scopus 로고
    • Transformation of pharmaceuticals in the environment: photolysis and other abiotic processes
    • ed. M. Petrovic and D. Barcelo), Elsevier Science, Amsterdam, Netherlands
    • Arnold, W.A. and McNeill, K. (2007) Transformation of pharmaceuticals in the environment: photolysis and other abiotic processes, in Analysis, Fate and Removal of Pharmaceuticals in the Water Cycle (ed. M. Petrovic and D. Barcelo), Elsevier Science, Amsterdam, Netherlands.
    • (2007) Analysis, Fate and Removal of Pharmaceuticals in the Water Cycle
    • Arnold, W.A.1    McNeill, K.2
  • 108
    • 23244458046 scopus 로고    scopus 로고
    • Application of time-of-flight mass spectrometry to the analysis of phototransformation products of diclofenac in water under natural sunlight
    • Agüera, A., Pérez Estrada, L.A., Ferrer, I. et al. (2005) Application of time-of-flight mass spectrometry to the analysis of phototransformation products of diclofenac in water under natural sunlight. Journal of Mass Spectrometry, 40, 908-915.
    • (2005) Journal of Mass Spectrometry , vol.40 , pp. 908-915
    • Agüera, A.1    Pérez Estrada, L.A.2    Ferrer, I.3
  • 109
    • 0032533389 scopus 로고    scopus 로고
    • Occurrence and fate of the pharmaceutical drug diclofenac in surface waters: rapid photodegradation in a lake
    • Buser, H., Poiger, T., and Muller, M.D. (1998) Occurrence and fate of the pharmaceutical drug diclofenac in surface waters: rapid photodegradation in a lake. Environmental Science & Technology, 32, 3449-3456.
    • (1998) Environmental Science & Technology , vol.32 , pp. 3449-3456
    • Buser, H.1    Poiger, T.2    Muller, M.D.3
  • 112
    • 77950037043 scopus 로고    scopus 로고
    • Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
    • Schulze, T., Weiss, S., Schymanski, E. et al. (2010) Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis. Environmental Pollution, 158, 1461-1466.
    • (2010) Environmental Pollution , vol.158 , pp. 1461-1466
    • Schulze, T.1    Weiss, S.2    Schymanski, E.3
  • 113
    • 0023953665 scopus 로고
    • A comparative study of the photochemistry of the nonsteroidal anti-inflammatory drugs, naproxen, benoxaproxen and indomethacin
    • Moore, D.E. and Chappuis, P.P. (1988) A comparative study of the photochemistry of the nonsteroidal anti-inflammatory drugs, naproxen, benoxaproxen and indomethacin. Photochemistry and Photobiology, 47, 173-180.
    • (1988) Photochemistry and Photobiology , vol.47 , pp. 173-180
    • Moore, D.E.1    Chappuis, P.P.2
  • 116
    • 0023489025 scopus 로고
    • Photolytic degradation of ibuprofen, Toxicity of the isolated photoproducts on fibroblasts and erythrocytes
    • Castell, J.V., Gomez-L., M.J., Miranda, M.A., and Morera, I.M. (1987) Photolytic degradation of ibuprofen. Toxicity of the isolated photoproducts on fibroblasts and erythrocytes. Photochemistry and Photobiology, 46, 991-996.
    • (1987) Photochemistry and Photobiology , vol.46 , pp. 991-996
    • Castell, J.V.1    Gomez, L.M.J.2    Miranda, M.A.3    Morera, I.M.4
  • 117
    • 58149467674 scopus 로고    scopus 로고
    • Photodegradation of carbamazepine, ibuprofen, ketoprofen and 17a-ethinylestradiol in fresh and seawater
    • Matamoros, V., Aurélie, D., Albaigés, J., and Bayona, J. (2009) Photodegradation of carbamazepine, ibuprofen, ketoprofen and 17a-ethinylestradiol in fresh and seawater. Water, Air, & Soil Pollution, 196, 161-168.
    • (2009) Water, Air, & Soil Pollution , vol.196 , pp. 161-168
    • Matamoros, V.1    Aurélie, D.2    Albaigés, J.3    Bayona, J.4
  • 119
    • 43049180321 scopus 로고    scopus 로고
    • Photodegradation study of three dipyrone metabolites in various water systems: Identification and toxicity of their photodegradation products
    • Gómez, M.J., Sirtori, C., Mezcua, M. et al. (2008) Photodegradation study of three dipyrone metabolites in various water systems: Identification and toxicity of their photodegradation products. Water Research, 42, 2698-2706.
    • (2008) Water Research , vol.42 , pp. 2698-2706
    • Gómez, M.J.1    Sirtori, C.2    Mezcua, M.3
  • 120
    • 33749384780 scopus 로고    scopus 로고
    • Photodegradation processes of the antiepileptic drug carbamazepine, relevant to estuarine waters
    • Chiron, S., Minero, C., and Vione, D. (2006) Photodegradation processes of the antiepileptic drug carbamazepine, relevant to estuarine waters. Environmental Science & Technology, 40, 5977-5983.
    • (2006) Environmental Science & Technology , vol.40 , pp. 5977-5983
    • Chiron, S.1    Minero, C.2    Vione, D.3
  • 121
    • 20044371846 scopus 로고    scopus 로고
    • Photodegradation of the pharmaceuticals atorvastatin, carbamazepine, levofloxacin, and sulfamethoxazole in natural waters
    • Lam, M.W. and Mabury, S.A. (2005) Photodegradation of the pharmaceuticals atorvastatin, carbamazepine, levofloxacin, and sulfamethoxazole in natural waters. Aquatic Sciences, 67, 177-188.
    • (2005) Aquatic Sciences , vol.67 , pp. 177-188
    • Lam, M.W.1    Mabury, S.A.2
  • 123
    • 77950953200 scopus 로고    scopus 로고
    • Effect of water-matrix composition on Trimethoprim solar photodegradation kinetics and pathways
    • Sirtori, C., Agüera, A., Gernjak, W., and Malato, S. (2010) Effect of water-matrix composition on Trimethoprim solar photodegradation kinetics and pathways. Water Research, 44, 2735-2744.
    • (2010) Water Research , vol.44 , pp. 2735-2744
    • Sirtori, C.1    Agüera, A.2    Gernjak, W.3    Malato, S.4
  • 125
    • 77956060484 scopus 로고    scopus 로고
    • Photodegradation of flupentixol in aqueous solution under irradiation at 254nm: Identification of the photoproducts generated
    • Maquille, A., Salembier, S., Hérent, M., and Habib Jiwan, J. (2010) Photodegradation of flupentixol in aqueous solution under irradiation at 254nm: Identification of the photoproducts generated. Journal of Photochemistry and Photobiology A, 214, 224-229.
    • (2010) Journal of Photochemistry and Photobiology A , vol.214 , pp. 224-229
    • Maquille, A.1    Salembier, S.2    Hérent, M.3    Habib Jiwan, J.4
  • 126
    • 33846786963 scopus 로고    scopus 로고
    • Kinetics and degradation products for direct photolysis of b-blockers in water
    • Liu, Q. and Williams, H.E. (2007) Kinetics and degradation products for direct photolysis of b-blockers in water. Environmental Science & Technology, 41, 803-810.
    • (2007) Environmental Science & Technology , vol.41 , pp. 803-810
    • Liu, Q.1    Williams, H.E.2
  • 127
    • 67449142579 scopus 로고    scopus 로고
    • Photo-induced environmental depletion processes of b-blockers in river waters
    • Liu, Q., Cumming, R.I., and Sharpe, A.D. (2009) Photo-induced environmental depletion processes of b-blockers in river waters. Photochemical & Photobiological Sciences, 8, 768-777.
    • (2009) Photochemical & Photobiological Sciences , vol.8 , pp. 768-777
    • Liu, Q.1    Cumming, R.I.2    Sharpe, A.D.3
  • 128
    • 77649272779 scopus 로고    scopus 로고
    • Direct UV photolysis of propranolol and metronidazole in aqueous solution
    • Dantas, R.F., Rossiter, O., Teixeira, A.K.R. et al. (2010) Direct UV photolysis of propranolol and metronidazole in aqueous solution. Chemical Engineering Journal, 158, 143-147.
    • (2010) Chemical Engineering Journal , vol.158 , pp. 143-147
    • Dantas, R.F.1    Rossiter, O.2    Teixeira, A.K.R.3
  • 129
    • 50049101178 scopus 로고    scopus 로고
    • Aqueous photolysis of tetracycline and toxicity of photolytic products to luminescent bacteria
    • Jiao, S., Zheng, S., Yin, D. et al. (2008) Aqueous photolysis of tetracycline and toxicity of photolytic products to luminescent bacteria. Chemosphere, 73, 377-382.
    • (2008) Chemosphere , vol.73 , pp. 377-382
    • Jiao, S.1    Zheng, S.2    Yin, D.3
  • 130
    • 67349283382 scopus 로고    scopus 로고
    • Photo-degradation of the antimicrobial ciprofloxacin at high pH: Identification and biodegradability assessment of the primary byproducts
    • Vasconcelos, T.G., Henriques, D.M., König, A. et al. (2009) Photo-degradation of the antimicrobial ciprofloxacin at high pH: Identification and biodegradability assessment of the primary byproducts. Chemosphere, 76, 487-493.
    • (2009) Chemosphere , vol.76 , pp. 487-493
    • Vasconcelos, T.G.1    Henriques, D.M.2    König, A.3
  • 131
    • 67849121317 scopus 로고    scopus 로고
    • In vitro residual anti-bacterial activity of difloxacin, sarafloxacin and their photoproducts after photolysis in water
    • Kusari, S., Prabhakaran, D., Lamshöft, M., and Spiteller, M. (2009) In vitro residual anti-bacterial activity of difloxacin, sarafloxacin and their photoproducts after photolysis in water. Environmental Pollution, 157, 2722-2730.
    • (2009) Environmental Pollution , vol.157 , pp. 2722-2730
    • Kusari, S.1    Prabhakaran, D.2    Lamshöft, M.3    Spiteller, M.4
  • 134
    • 33947195768 scopus 로고    scopus 로고
    • Phototransformation products of tamoxifen by sunlight in water, Toxicity of the drug and its derivatives on aquatic organisms
    • DellaGreca, M., Iesce, M.R., Isidori, M., Nardelli, A., Previtera, L., and Rubino, M. (2007) Phototransformation products of tamoxifen by sunlight in water. Toxicity of the drug and its derivatives on aquatic organisms. Chemosphere, 67 (10), 1933-1939.
    • (2007) Chemosphere , vol.67 , Issue.10 , pp. 1933-1939
    • DellaGreca, M.1    Iesce, M.R.2    Isidori, M.3    Nardelli, A.4    Previtera, L.5    Rubino, M.6
  • 135
    • 34248639066 scopus 로고    scopus 로고
    • Toxic and genotoxic impact of fibrates and their photoproducts on non-target organisms
    • Isidori, M., Nardelli, A., Pascarella, L., Rubino, M., and Parrella, A. (2007) Toxic and genotoxic impact of fibrates and their photoproducts on non-target organisms. Environment International, 33, 635-641.
    • (2007) Environment International , vol.33 , pp. 635-641
    • Isidori, M.1    Nardelli, A.2    Pascarella, L.3    Rubino, M.4    Parrella, A.5
  • 136
    • 84862684969 scopus 로고    scopus 로고
    • Captopril and its dimer captopril disulfide: Photodegradation, aerobic biodegradation and identification of transformation products by HPLC-UV and LC-ion trap-MSn
    • Mahmoud, W.M.M., and Kümmerer, K. (2012) Captopril and its dimer captopril disulfide: Photodegradation, aerobic biodegradation and identification of transformation products by HPLC-UV and LC-ion trap-MSn. Chemosphere, 88(10), 1170-1177.
    • (2012) Chemosphere , vol.88 , Issue.10 , pp. 1170-1177
    • Mahmoud, W.M.M.1    Kümmerer, K.2
  • 137
    • 0032501126 scopus 로고    scopus 로고
    • Mechanisms of photosensitization by phototoxic drugs
    • Moore, D.E. (1998) Mechanisms of photosensitization by phototoxic drugs. Mutation Research, 422, 165-173.
    • (1998) Mutation Research , vol.422 , pp. 165-173
    • Moore, D.E.1
  • 138
    • 0001200478 scopus 로고    scopus 로고
    • Photochemistry of 2,6-dichlorodiphenylamine and 1-chlorocarbazole, the photoactive chromophores of diclofenac, meclofenamic acid and their major photoproducts
    • Encinas, S., Bosca, F., and Miranda, M.A. (1998) Photochemistry of 2,6-dichlorodiphenylamine and 1-chlorocarbazole, the photoactive chromophores of diclofenac, meclofenamic acid and their major photoproducts. Photochemistry and Photobiology, 68, 640-645.
    • (1998) Photochemistry and Photobiology , vol.68 , pp. 640-645
    • Encinas, S.1    Bosca, F.2    Miranda, M.A.3
  • 139
    • 0035145257 scopus 로고    scopus 로고
    • Photodegradation of the pharmaceutical drug diclofenac in a lake: Pathway, field measurements, and mathematical modeling
    • Poiger, T., Buser, H., and Müller, M.D. (2001) Photodegradation of the pharmaceutical drug diclofenac in a lake: Pathway, field measurements, and mathematical modeling. Environmental Toxicology and Chemistry, 20, 256-263.
    • (2001) Environmental Toxicology and Chemistry , vol.20 , pp. 256-263
    • Poiger, T.1    Buser, H.2    Müller, M.D.3
  • 141
    • 0035987825 scopus 로고    scopus 로고
    • Carbamazepine in water: persistence in the environment, ozonation treatment and preliminary assessment on algal toxicity
    • Andreozzi, R., Marotta, R., Pinto, G., and Pollio, A. (2002) Carbamazepine in water: persistence in the environment, ozonation treatment and preliminary assessment on algal toxicity. Water Research, 36, 2869-2877.
    • (2002) Water Research , vol.36 , pp. 2869-2877
    • Andreozzi, R.1    Marotta, R.2    Pinto, G.3    Pollio, A.4
  • 142
    • 0842324551 scopus 로고    scopus 로고
    • Kinetic study of photocatalytic degradation of carbamazepine, clofibric acid, iomeprol and iopromide assisted by different TiO2 materials-determination of intermediates and reaction pathways
    • Doll, T.E. and Frimmel, F.H. (2004) Kinetic study of photocatalytic degradation of carbamazepine, clofibric acid, iomeprol and iopromide assisted by different TiO2 materials-determination of intermediates and reaction pathways. Water Research, 38, 955-964.
    • (2004) Water Research , vol.38 , pp. 955-964
    • Doll, T.E.1    Frimmel, F.H.2
  • 143
    • 1542647133 scopus 로고    scopus 로고
    • Advanced oxidation of the pharmaceutical drug diclofenac with UV/H2O2 and ozone
    • Vogna, D., Marotta, R., Napolitano, A. et al. (2004) Advanced oxidation of the pharmaceutical drug diclofenac with UV/H2O2 and ozone. Water Research, 38, 414-422.
    • (2004) Water Research , vol.38 , pp. 414-422
    • Vogna, D.1    Marotta, R.2    Napolitano, A.3
  • 145
    • 0022578338 scopus 로고
    • In vitro evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones
    • Stamm, J.M., Hanson, C.W., Chu, D.T. et al. (1986) In vitro evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones. Antimicrobial Agents and Chemotherapy, 29, 193-200.
    • (1986) Antimicrobial Agents and Chemotherapy , vol.29 , pp. 193-200
    • Stamm, J.M.1    Hanson, C.W.2    Chu, D.T.3
  • 146
    • 61749101241 scopus 로고    scopus 로고
    • Metabolism and excretion kinetics of 14Clabeled and non-labeled difloxacin in pigs after oral administration, and antimicrobial activity of manure containing difloxacin and its metabolites
    • Sukul, P., Lamshöft, M., Kusari, S. et al. (2009) Metabolism and excretion kinetics of 14Clabeled and non-labeled difloxacin in pigs after oral administration, and antimicrobial activity of manure containing difloxacin and its metabolites. Environmental Research, 109, 225-231.
    • (2009) Environmental Research , vol.109 , pp. 225-231
    • Sukul, P.1    Lamshöft, M.2    Kusari, S.3
  • 147
    • 0035093338 scopus 로고    scopus 로고
    • Antimicrobial activity of fluoroquinolone photodegradation products determined by parallel-line bioassay and high performance liquid chromatography
    • Sunderland, J., Tobin, C.M., Hedges, A.J. et al. (2001) Antimicrobial activity of fluoroquinolone photodegradation products determined by parallel-line bioassay and high performance liquid chromatography. The Journal of Antimicrobial Chemotherapy, 47, 271-275.
    • (2001) The Journal of Antimicrobial Chemotherapy , vol.47 , pp. 271-275
    • Sunderland, J.1    Tobin, C.M.2    Hedges, A.J.3
  • 148
    • 84863205735 scopus 로고    scopus 로고
    • Genotoxic effect of ciprofloxacin during photolytic decomposition monitored by the in vitro micronucleus test (MNvit) in HepG2 cells
    • Garcia-Käufer, M., Haddad, T., Bergheim, M. et al. (2012) Genotoxic effect of ciprofloxacin during photolytic decomposition monitored by the in vitro micronucleus test (MNvit) in HepG2 cells. Environmental Science and Pollution Research, 19, 1719-1727.
    • (2012) Environmental Science and Pollution Research , vol.19 , pp. 1719-1727
    • Garcia-Käufer, M.1    Haddad, T.2    Bergheim, M.3
  • 149
    • 84878422003 scopus 로고    scopus 로고
    • Chronic ecotoxic effects to Pseudomonas putida and Vibrio fischeri, and cytostatic and genotoxic effects to the hepatoma cell line (HepG2) of ofloxacin photo(cata)lytically treated solutions
    • Vasquez, M.I., Garcia-Käufer, M., Hapeshi, E. et al. (2012) Chronic ecotoxic effects to Pseudomonas putida and Vibrio fischeri, and cytostatic and genotoxic effects to the hepatoma cell line (HepG2) of ofloxacin photo(cata)lytically treated solutions. The Science of the Total Environment, 450-451, 356-365.
    • (2012) The Science of the Total Environment , vol.450-451 , pp. 356-365
    • Vasquez, M.I.1    Garcia-Käufer, M.2    Hapeshi, E.3
  • 150
    • 84874306975 scopus 로고    scopus 로고
    • Biodegradation potential of ofloxacin and its resulting transformation products during photolytic and photocatalytic treatment
    • Vasquez, M., Hapeshi, E., Fatta-Kassinos, D., and Kümmerer, K. (2012) Biodegradation potential of ofloxacin and its resulting transformation products during photolytic and photocatalytic treatment. Environmental Science and Pollution Research, 20(3), 1302-1309.
    • (2012) Environmental Science and Pollution Research , vol.20 , Issue.3 , pp. 1302-1309
    • Vasquez, M.1    Hapeshi, E.2    Fatta-Kassinos, D.3    Kümmerer, K.4
  • 151
    • 43049180321 scopus 로고    scopus 로고
    • Photodegradation study of three dipyrone metabolites in various water systems: Identification and toxicity of their photodegradation products
    • Gómez, M.J., Sirtori, C., Mezcua, M., Fernández-Alba, A.R., and Agüera, A. (2008) Photodegradation study of three dipyrone metabolites in various water systems: Identification and toxicity of their photodegradation products. Water Research, 42(10-11), 2698-2706.
    • (2008) Water Research , vol.42 , Issue.10-11 , pp. 2698-2706
    • Gómez, M.J.1    Sirtori, C.2    Mezcua, M.3    Fernández-Alba, A.R.4    Agüera, A.5
  • 152
    • 62749091566 scopus 로고    scopus 로고
    • Effects of ozone pre-treatment on diclofenac: Intermediates, biodegradability and toxicity assessment
    • Coelho, A.D., Sans, C., Agüera, A. et al. (2009) Effects of ozone pre-treatment on diclofenac: Intermediates, biodegradability and toxicity assessment. The Science of the Total Environment, 407, 3572-3578.
    • (2009) The Science of the Total Environment , vol.407 , pp. 3572-3578
    • Coelho, A.D.1    Sans, C.2    Agüera, A.3
  • 153
    • 78650535643 scopus 로고    scopus 로고
    • Degradation of the antibiotic amoxicillin by photo-Fenton process-Chemical and toxicological assessment
    • Trovó, A.G., Pupo Nogueira, R.F., Agüera, A. et al. (2011) Degradation of the antibiotic amoxicillin by photo-Fenton process-Chemical and toxicological assessment. Water Research, 45, 1394-1402.
    • (2011) Water Research , vol.45 , pp. 1394-1402
    • Trovó, A.G.1    Pupo Nogueira, R.F.2    Agüera, A.3
  • 154
    • 69849113841 scopus 로고    scopus 로고
    • Degradation of sulfamethoxazole in water by solar photo-Fenton, Chemical and toxicological evaluation
    • Trovó, A.G., Nogueira, R.F.P., Agüera, A. et al. (2009) Degradation of sulfamethoxazole in water by solar photo-Fenton. Chemical and toxicological evaluation. Water Research, 43, 3922-3931.
    • (2009) Water Research , vol.43 , pp. 3922-3931
    • Trovó, A.G.1    Nogueira, R.F.P.2    Agüera, A.3
  • 155
    • 78651431969 scopus 로고    scopus 로고
    • Solar photo-Fenton degradation of nalidixic acid in waters and wastewaters of different composition, Analytical assessment by LC-TOF-MS
    • Sirtori, C., Zapata, A., Gernjak, W. et al. (2011) Solar photo-Fenton degradation of nalidixic acid in waters and wastewaters of different composition. Analytical assessment by LC-TOF-MS. Water Research, 45, 1736-1744.
    • (2011) Water Research , vol.45 , pp. 1736-1744
    • Sirtori, C.1    Zapata, A.2    Gernjak, W.3
  • 156
    • 84861422486 scopus 로고    scopus 로고
    • Solar photocatalytic treatment of trimethoprim in four environmental matrices at a pilot scale: Transformation products and ecotoxicity evaluation
    • Michael, I., Hapeshi, E., Osorio, V. et al. (2012) Solar photocatalytic treatment of trimethoprim in four environmental matrices at a pilot scale: Transformation products and ecotoxicity evaluation. The Science of the Total Environment, 430, 167-173.
    • (2012) The Science of the Total Environment , vol.430 , pp. 167-173
    • Michael, I.1    Hapeshi, E.2    Osorio, V.3
  • 157
    • 34147215935 scopus 로고    scopus 로고
    • Electro-Fenton degradation of antimicrobials triclosan and triclocarban
    • Sirés, I., Oturan, N., Oturan, M.A. et al. (2007) Electro-Fenton degradation of antimicrobials triclosan and triclocarban. Electrochimica Acta, 52, 5493-5503.
    • (2007) Electrochimica Acta , vol.52 , pp. 5493-5503
    • Sirés, I.1    Oturan, N.2    Oturan, M.A.3
  • 158
    • 75849131818 scopus 로고    scopus 로고
    • Degradation of the emerging contaminant ibuprofen in water by photo-Fenton
    • Méndez-Arriaga, F., Esplugas, S., and Giménez, J. (2010) Degradation of the emerging contaminant ibuprofen in water by photo-Fenton. Water Research, 44, 589-595.
    • (2010) Water Research , vol.44 , pp. 589-595
    • Méndez-Arriaga, F.1    Esplugas, S.2    Giménez, J.3
  • 159
    • 59349087225 scopus 로고    scopus 로고
    • Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment
    • Radjenovíc, J., Petrovíc, M., and Barceló, D. (2009) Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment. Water Research, 43, 831-841.
    • (2009) Water Research , vol.43 , pp. 831-841
    • Radjenovíc, J.1    Petrovíc, M.2    Barceló, D.3
  • 160
    • 67649427429 scopus 로고    scopus 로고
    • Photocatalytic degradation of sulfa drugs with TiO2, Fe salts and TiO2/FeCl3 in aquatic environment-Kinetics and degradation pathway
    • Baran, W., Adamek, E., Sobczak, A., and Makowski, A. (2009) Photocatalytic degradation of sulfa drugs with TiO2, Fe salts and TiO2/FeCl3 in aquatic environment-Kinetics and degradation pathway. Applied Catalysis B: Environmental, 90, 516-525.
    • (2009) Applied Catalysis B: Environmental , vol.90 , pp. 516-525
    • Baran, W.1    Adamek, E.2    Sobczak, A.3    Makowski, A.4
  • 161
    • 77949340630 scopus 로고    scopus 로고
    • Characterization of intermediate products of solar photocatalytic degradation of ranitidine at pilot-scale
    • Radjenovíc, J., Sirtori, C., Petrovíc, M. et al. (2010) Characterization of intermediate products of solar photocatalytic degradation of ranitidine at pilot-scale. Chemosphere, 79, 368-376.
    • (2010) Chemosphere , vol.79 , pp. 368-376
    • Radjenovíc, J.1    Sirtori, C.2    Petrovíc, M.3
  • 162
    • 63449122448 scopus 로고    scopus 로고
    • Phototransformation of selected human-used macrolides in surface water: Kinetics, model predictions and degradation pathways
    • Vione, D., Feitosa-Felizzola, J., Minero, C., and Chiron, S. (2009) Phototransformation of selected human-used macrolides in surface water: Kinetics, model predictions and degradation pathways. Water Research, 43, 1959-1967.
    • (2009) Water Research , vol.43 , pp. 1959-1967
    • Vione, D.1    Feitosa-Felizzola, J.2    Minero, C.3    Chiron, S.4
  • 163
    • 65549098072 scopus 로고    scopus 로고
    • Solar photocatalytic treatment of quinolones: intermediates and toxicity evaluation
    • Sirtori, C., Zapata, A., Malato, S. et al. (2009) Solar photocatalytic treatment of quinolones: intermediates and toxicity evaluation. Photochemical & Photobiological Sciences, 8, 644-651.
    • (2009) Photochemical & Photobiological Sciences , vol.8 , pp. 644-651
    • Sirtori, C.1    Zapata, A.2    Malato, S.3
  • 164
    • 34249087700 scopus 로고    scopus 로고
    • Oxidation of sulfamethoxazole and related antimicrobial agents by TiO2 photocatalysis
    • Hu, L., Flanders, P.M., Miller, P.L., and Strathmann, T.J. (2007) Oxidation of sulfamethoxazole and related antimicrobial agents by TiO2 photocatalysis. Water Research, 41, 2612-2626.
    • (2007) Water Research , vol.41 , pp. 2612-2626
    • Hu, L.1    Flanders, P.M.2    Miller, P.L.3    Strathmann, T.J.4
  • 165
    • 36049026304 scopus 로고    scopus 로고
    • Heterogeneous photocatalytic degradation of the pharmaceutical agent salbutamol in aqueous titanium dioxide suspensions
    • Sakkas, V.A., Calza, P., Medana, C. et al. (2007) Heterogeneous photocatalytic degradation of the pharmaceutical agent salbutamol in aqueous titanium dioxide suspensions. Applied Catalysis B: Environmental, 77, 135-144.
    • (2007) Applied Catalysis B: Environmental , vol.77 , pp. 135-144
    • Sakkas, V.A.1    Calza, P.2    Medana, C.3
  • 166
    • 46449136305 scopus 로고    scopus 로고
    • Photodegradation of acetaminophen in TiO2 suspended solution
    • Zhang, X., Wu, F., Wu, X. et al. (2008) Photodegradation of acetaminophen in TiO2 suspended solution. Journal of Hazardous Materials, 157, 300-307.
    • (2008) Journal of Hazardous Materials , vol.157 , pp. 300-307
    • Zhang, X.1    Wu, F.2    Wu, X.3
  • 167
    • 33845676314 scopus 로고    scopus 로고
    • Degradation of diclofenac in water by heterogeneous catalytic oxidation with H2O2
    • Hofmann, J., Freier, U., Wecks, M., and Hohmann, S. (2007) Degradation of diclofenac in water by heterogeneous catalytic oxidation with H2O2. Applied Catalysis B: Environmental, 70, 447-451.
    • (2007) Applied Catalysis B: Environmental , vol.70 , pp. 447-451
    • Hofmann, J.1    Freier, U.2    Wecks, M.3    Hohmann, S.4
  • 168
    • 33748297787 scopus 로고    scopus 로고
    • Photocatalytic degradation study of diclofenac over aqueous TiO2 suspensions
    • Calza, P., Sakkas, V.A., Medana, C. et al. (2006) Photocatalytic degradation study of diclofenac over aqueous TiO2 suspensions. Applied Catalysis B: Environmental, 67, 197-205.
    • (2006) Applied Catalysis B: Environmental , vol.67 , pp. 197-205
    • Calza, P.1    Sakkas, V.A.2    Medana, C.3
  • 169
    • 43049128918 scopus 로고    scopus 로고
    • Photocatalytic degradation of non-steroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation
    • Méndez-Arriaga, F., Esplugas, S., and Giménez, J. (2008) Photocatalytic degradation of non-steroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation. Water Research, 42, 585-594.
    • (2008) Water Research , vol.42 , pp. 585-594
    • Méndez-Arriaga, F.1    Esplugas, S.2    Giménez, J.3
  • 170
    • 77957368479 scopus 로고    scopus 로고
    • Degradation of the antibiotic oxolinic acid by photocatalysis with TiO2 in suspension
    • Giraldo, A.L., Peñuela, G.A., Torres-Palma, R.A. et al. (2010) Degradation of the antibiotic oxolinic acid by photocatalysis with TiO2 in suspension. Water Research, 44, 5158-5167.
    • (2010) Water Research , vol.44 , pp. 5158-5167
    • Giraldo, A.L.1    Peñuela, G.A.2    Torres-Palma, R.A.3
  • 171
    • 39149113440 scopus 로고    scopus 로고
    • Identification of photocatalytic degradation products of bezafibrate in TiO2 aqueous suspensions by liquid and gas chromatography
    • Lambropoulou, D.A., Hernando, M.D., Konstantinou, I.K. et al. (2008) Identification of photocatalytic degradation products of bezafibrate in TiO2 aqueous suspensions by liquid and gas chromatography. Journal of Chromatography A, 1183, 38-48.
    • (2008) Journal of Chromatography A , vol.1183 , pp. 38-48
    • Lambropoulou, D.A.1    Hernando, M.D.2    Konstantinou, I.K.3
  • 172
    • 77952548070 scopus 로고    scopus 로고
    • Photolytic and photocatalytic decomposition of aqueous ciprofloxacin: Transformation products and residual antibacterial activity
    • Paul, T., Dodd, M.C., and Strathmann, T.J. (2010) Photolytic and photocatalytic decomposition of aqueous ciprofloxacin: Transformation products and residual antibacterial activity. Water Research, 44, 3121-3132.
    • (2010) Water Research , vol.44 , pp. 3121-3132
    • Paul, T.1    Dodd, M.C.2    Strathmann, T.J.3
  • 173
    • 79959760780 scopus 로고    scopus 로고
    • Chemical and toxicological evolution of the antibiotic sulfamethoxazole under ozone treatment in water solution
    • Gómez-Ramos, M.d.M., Mezcua, M., Agüera, A. et al. (2011) Chemical and toxicological evolution of the antibiotic sulfamethoxazole under ozone treatment in water solution. Journal of Hazardous Materials, 192, 18-25.
    • (2011) Journal of Hazardous Materials , vol.192 , pp. 18-25
    • Gómez-Ramos, M.d.M.1    Mezcua, M.2    Agüera, A.3
  • 174
    • 69549103661 scopus 로고    scopus 로고
    • Evidencing generation of persistent ozonation products of antibiotics roxithromycin and trimethoprim
    • Radjenovic, J., Godehardt, M., Petrovic, M. et al. (2009) Evidencing generation of persistent ozonation products of antibiotics roxithromycin and trimethoprim. Environmental Science & Technology, 43, 6808-6815.
    • (2009) Environmental Science & Technology , vol.43 , pp. 6808-6815
    • Radjenovic, J.1    Godehardt, M.2    Petrovic, M.3
  • 175
    • 71749086283 scopus 로고    scopus 로고
    • Identification of intermediates and assessment of ecotoxicity in the oxidation products generated during the ozonation of clofibric acid
    • Rosal, R., Gonzalo, M.S., Boltes, K. et al. (2009) Identification of intermediates and assessment of ecotoxicity in the oxidation products generated during the ozonation of clofibric acid. Journal of Hazardous Materials, 172, 1061-1068.
    • (2009) Journal of Hazardous Materials , vol.172 , pp. 1061-1068
    • Rosal, R.1    Gonzalo, M.S.2    Boltes, K.3
  • 176
    • 0346729991 scopus 로고    scopus 로고
    • Kinetic and chemical assessment of the UV/ H2O2 treatment of antiepileptic drug carbamazepine
    • Vogna, D., Marotta, R., Andreozzi, R. et al. (2004) Kinetic and chemical assessment of the UV/ H2O2 treatment of antiepileptic drug carbamazepine. Chemosphere, 54, 497-505.
    • (2004) Chemosphere , vol.54 , pp. 497-505
    • Vogna, D.1    Marotta, R.2    Andreozzi, R.3
  • 177
    • 80053904340 scopus 로고    scopus 로고
    • Oxidation by-products and ecotoxicity assessment during the photodegradation of fenofibric acid in aqueous solution with UVand UV/H2O2
    • Santiago, J., Agüera, A., del Mar Gómez-Ramos, M. et al. (2011) Oxidation by-products and ecotoxicity assessment during the photodegradation of fenofibric acid in aqueous solution with UVand UV/H2O2. Journal of Hazardous Materials, 194, 30-41.
    • (2011) Journal of Hazardous Materials , vol.194 , pp. 30-41
    • Santiago, J.1    Agüera, A.2    del Mar Gómez-Ramos, M.3
  • 178
    • 78649978955 scopus 로고    scopus 로고
    • Photodegradation and toxicity changes of antibiotics in UV and UV/H2O2 process
    • Yuan, F., Hu, C., Hu, X., Wie, D., Chen, Y., and Qu, J. (2011) Photodegradation and toxicity changes of antibiotics in UV and UV/H2O2 process. Journal of Hazardous Materials, 185, 1256-1263.
    • (2011) Journal of Hazardous Materials , vol.185 , pp. 1256-1263
    • Yuan, F.1    Hu, C.2    Hu, X.3    Wie, D.4    Chen, Y.5    Qu, J.6
  • 179
    • 43049128918 scopus 로고    scopus 로고
    • Photocatalytic degradation of nonsteroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation
    • Méndez-Arriaga, F., Esplugas, S., and Giménez, J. (2008) Photocatalytic degradation of nonsteroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation. Water Research, 42, 585-594.
    • (2008) Water Research , vol.42 , pp. 585-594
    • Méndez-Arriaga, F.1    Esplugas, S.2    Giménez, J.3
  • 180
    • 75849131818 scopus 로고    scopus 로고
    • Degradation of the emerging contaminant ibuprofen in water by photo-Fenton
    • Méndez-Arriaga, F., Esplugas, S., and Giménez, J. (2010) Degradation of the emerging contaminant ibuprofen in water by photo-Fenton. Water Research, 44, 589-595.
    • (2010) Water Research , vol.44 , pp. 589-595
    • Méndez-Arriaga, F.1    Esplugas, S.2    Giménez, J.3
  • 182
    • 0031105441 scopus 로고    scopus 로고
    • Photogeneration of fluoride by the fluoroquinolone antimicrobial agents lomefloxacin and fleroxacin
    • Martinez, L.J., Li, G., and Chignell, C.F. (1997) Photogeneration of fluoride by the fluoroquinolone antimicrobial agents lomefloxacin and fleroxacin. Photochemistry and Photobiology, 65, 599-602.
    • (1997) Photochemistry and Photobiology , vol.65 , pp. 599-602
    • Martinez, L.J.1    Li, G.2    Chignell, C.F.3
  • 184
    • 84856079170 scopus 로고    scopus 로고
    • Trimethoprim: Kinetic and mechanistic considerations in photochemical environmental fate and AOP treatment
    • Luo, X., Zheng, Z., Greaves, J. et al. (2012) Trimethoprim: Kinetic and mechanistic considerations in photochemical environmental fate and AOP treatment. Water Research, 46, 1327-1336.
    • (2012) Water Research , vol.46 , pp. 1327-1336
    • Luo, X.1    Zheng, Z.2    Greaves, J.3
  • 185
    • 34447270963 scopus 로고    scopus 로고
    • Visible-light-mediated TiO2 photocatalysis of fluoroquinolone antibacterial agents
    • Paul, T., Miller, P.L., and Strathmann, T.J. (2007) Visible-light-mediated TiO2 photocatalysis of fluoroquinolone antibacterial agents. Environmental Science & Technology, 41, 4720-4727.
    • (2007) Environmental Science & Technology , vol.41 , pp. 4720-4727
    • Paul, T.1    Miller, P.L.2    Strathmann, T.J.3
  • 187
    • 84857758206 scopus 로고    scopus 로고
    • Oxidation of the antiviral drug acyclovir and its biodegradation product carboxy-acyclovir with ozone: kinetics and identification of oxidation products
    • Prasse, C., Wagner, M., Schulz, R., and Ternes, T.A. (2012) Oxidation of the antiviral drug acyclovir and its biodegradation product carboxy-acyclovir with ozone: kinetics and identification of oxidation products. Environmental Science & Technology, 46, 2169-2178.
    • (2012) Environmental Science & Technology , vol.46 , pp. 2169-2178
    • Prasse, C.1    Wagner, M.2    Schulz, R.3    Ternes, T.A.4


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