Kinetics and degradation products for direct photolysis of β-blockers in water

Environmental Science and Technology

Volumn 41, Issue 3, 2007, Pages 803-810

  Liu, Qin Tao ^a   Williams, Helen E ^b  

^a ASTRAZENECA   (United Kingdom)

^b Pharmaceutical and Analytical Research and Development   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS (API); SOLAR IRRADIATOR;

ALCOHOLS; DEGRADATION; PHOTOLYSIS; REACTION KINETICS; SOLUTIONS;

DRUG PRODUCTS;

ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; METOPROLOL SUCCINATE; PROPRANOLOL; SURFACE WATER;

ALCOHOLS; DEGRADATION; DRUG PRODUCTS; PHOTOLYSIS; REACTION KINETICS; SOLUTIONS;

AQUEOUS SOLUTION; DRUG; FREE RADICAL; HALF LIFE; LIGHT INTENSITY; OXIDATION; PHOTODEGRADATION; PHOTOLYSIS; REACTION KINETICS; SOLAR RADIATION; SURFACE WATER; TRANSFORMATION; WATER POLLUTION;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; DEGRADATION; DEOXYGENATION; ELECTRON SPIN RESONANCE; OXIDATION; PHOTOLYSIS; SOLAR RADIATION; WATER ANALYSIS; WATER CONTAMINATION; WATER SAMPLING;

ADRENERGIC BETA-ANTAGONISTS; ATENOLOL; BIODEGRADATION, ENVIRONMENTAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FREE RADICAL SCAVENGERS; FRESH WATER; INDUSTRIAL WASTE; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; METOPROLOL; OXIDATION-REDUCTION; PHOTOLYSIS; PROPRANOLOL; SEASONS; WATER POLLUTANTS, CHEMICAL;

APIS;

EID: 33846786963     PISSN: 0013936X     EISSN: None     Source Type: Journal    
DOI: 10.1021/es0616130     Document Type: Article

References (22)

1. Organisation for Economic Co-operation and Development. Guideline for testing of chemicals: phototransformation of chemicals in water - direct and indirect photolysis, draft: August 2000; OECD: Paris, 2000.
2. Boreen, A. L.; Arnold, W. A.; McNeill, K. Photodegradation of pharmaceuticals in the aquatic environment: a review. Aquat. Sci. 2003, 65, 320-341.
3. Lam, M. W.; Young, C. J.; Brain, R. A.; Johnson, D. J.; Hanson, M. A.; Wilson, C. J.; Richards, S. M.; Solomon, K. R.; Mabury, S. A. Aquatic persistence of eight pharmaceuticals in a microcosm study. Environ. Toxicol. Chem. 2004, 23 (6), 1431-1440.
4. Werner, J. J.; McNeill, K.; Arnold, W.A. Environmental photodegradation of mefenamic acid. Chemosphere 2005, 58 (10), 1339-1346.
5. Liu, Q.-T.; Riddle, A. M.; Robinson, P. F.; Gray, N. Roles of partitioning and phototransformation in predicting the fate and movement of pharmaceuticals in UK and US rivers, In Proceedings 4th International Conference on Pharmaceuticals and EDCs in Water, Minneapolis, Minnesota, 13-15 October 2004; National Ground Water Association: Westerville, OH, 2004; pp 48-62.
6. Robinson, P. F.; Liu, Q.-T.; Riddle, A. M.; Murray-Smith, R. Modelling the impact of direct phototransformation on predicted environmental concentrations (PECs) of propranolol hydrochloride in UK and US rivers, Chemosphere 2007; 66 (4) 757-766.
7. Vieno, N. M.; Tuhkanen, T.; Kronberg, L. Seasonal variation in the occurrence of pharmaceuticals in effluents from a sewage treatment plant and in the recipient water. Environ. Sci. Technol. 2005, 39 (21), 8220-8226.
8. IMS 2005. IMS Health, MIDAS 21/03/2005.
9. Cunningham, V. L.; Constable, D. C.; Hannah, R. E. Environmental risk assessment of paroxetine. Environ. Sci. Technol. 2004, 38 (12), 3351-3359.
10. Aranami, K.; Readman, J. W. Photodegradation of triclosan and production of 2,7/2,8-dichlorodibenzo-p-dioxin in freshwater and seawater. Organohalogen Compd. 2005, 1918-1922.
11. Lam, M. W.; Young, C. J.; Mabury, S. A. Aqueous photochemical reaction kinetics and transformations of fluoxetine, Environ. Sci. Technol. 2005, 39 (2), 513-522.
12. 2 materials - determination of intermediates and reaction pathways. Water Res. 2004, 38 (4), 955-964.
13. Gallardo Cabrera, C., Goldberg de Waisbaum, R., Sbarbati Nudelman, N. Kinetic and mechanistic studies on the hydrolysis and photodegradation of diazepam and alprazolam. J. Phys. Org. Chem. 2005, 18, 156-161.
14. Andreozzi, R.; Raffaele, M.; Nicklas, P. Pharmaceuticals in STP effluents and their solar photodegration in aquatic environment. Chemosphere 2003, 50 (10), 1319-1330.
15. Lin, A. Y.-C.; Reinhard, M. Photodegradation of common environmental pharma-ceuticals and estrogens in river water. Environ. Toxicol. Chem. 2005, 24 (6), 1303-1309.
16. Andrisano.V.; Gotti, R.; Leoni, A.; Cavrini, V. Photodegradation studies on atenolol by liquid chromatography. J. Pharm. Biomed. Anal. 1999, 21, 851-857.
17. Zepp, R. G.; Cline, D. M. Rates of direct photolysis in aquatic environment. Environ. Sci. Technol. 1977, 11 (4), 359-366.
18. Leifer,A. The Kinetics of Environmental Aquatic Photochemistry, ACS Professional Reference Book; American Chemical Society: Washington, DC, 1988; pp 257-264.
19. Spalek, T.; Pietrzyk, P.; Sojka, Z. Application of the genetic algorithm joint with the powell method to nonlinear least squares fitting of powder EPR spectra. J. Chem. Inf. Model. 2005, 45, 18-29.
20. Sortino, S.; Petralia, S.; Boscà, F.; Miranda, M. A. Irreversible photo-oxidation of propranolol triggered by self-photogenerated singlet molecular oxygen. Photochem. Photobiol. Sci. 2002, 1, 136-140.
21. Frank, R. ; Klöpffer, W. Spectral solar photon irradiance in central Europe and the adjacent North Sea. Chemosphere 1988, 17, 985-994.
22. Li, A. S. W.; Cummings, K. B.; RoethLing, H. P.; Buettner, G. R.; Chignell, C. F. A spin trapping database implemented on the IBM PC/AT. J. Magn. Reson. 1988, 79, 140-142.