Captopril and its dimer captopril disulfide: Photodegradation, aerobic biodegradation and identification of transformation products by HPLC-UV and LC-ion trap-MSn

Chemosphere

Volumn 88, Issue 10, 2012, Pages 1170-1177

  Mahmoud, Waleed M M ^a,b   Kümmerer, Klaus ^a  

^a LEUPHANA UNIVERSITY OF LÜNEBURG   (Germany)

^b Suez Canal University   (Egypt)

Author keywords

Angiotensin converting enzyme (ACE) inhibitor; Aquatic environment; Biodegradation; Dead end metabolite; Photolysis; UV treatment

Indexed keywords

BIODEGRADABILITY; BOTTLES; DIMERS; EFFLUENTS; MERCURY COMPOUNDS; METABOLITES; MINERALOGY; PHOTOLYSIS; SULFUR COMPOUNDS; WELL TESTING;

AEROBIC BIODEGRADATION; ANGIOTENSIN CONVERTING ENZYME INHIBITOR (ACE); AQUATIC ENVIRONMENTS; DEAD-END METABOLITES; FURTHER TREATMENTS; PHOTODEGRADATION PRODUCTS; TRANSFORMATION PRODUCTS; UV TREATMENT;

BIODEGRADATION;

CAPTOPRIL; CAPTOPRIL DISULFIDE; DIMER; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; UNCLASSIFIED DRUG;

BACTERIUM; BIODEGRADATION; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; EFFLUENT; HOSPITAL SECTOR; HYPERTENSION; INHIBITOR; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITE; OECD; PHOTODEGRADATION; PHOTOLYSIS; TRANSFORMATION;

AEROBIC METABOLISM; ANALYTIC METHOD; AQUATIC ENVIRONMENT; ARTICLE; BIODEGRADABILITY; CLOSED BOTTLE TEST; DRUG STRUCTURE; EGYPT; ENVIRONMENTAL MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MANOMETRY; MINERALIZATION; PHOTODEGRADATION; PHOTOLYSIS; QUANTITATIVE ANALYSIS; ULTRAVIOLET SPECTROSCOPY;

EGYPT;

EID: 84862684969     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.03.064     Document Type: Article

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