Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment

Chemosphere

Volumn 50, Issue 10, 2003, Pages 1319-1330

  Andreozzi, Roberto ^a   Marotta, Raffaele ^a   Paxéus, Nicklas ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Karl IX:s väg   (Sweden)

Author keywords

Abiotic processes; Pharmaceutical; Phototransformations; Sensitizers; Sewage treatment plant effluents

Indexed keywords

EFFLUENTS; ORGANIC ACIDS; PHOTODEGRADATION; PHOTOSENSITIZERS; SEWAGE TREATMENT PLANTS; SOLUTIONS;

QUANTUM YIELDS;

DRUG PRODUCTS;

CARBAMAZEPINE; CLOFIBRIC ACID; DICLOFENAC; HUMIC ACID; OFLOXACIN; PHOTOSENSITIZING AGENT; PROPRANOLOL; SULFAMETHOXAZOLE; SURFACE WATER;

PHOTODEGRADATION;

AQUATIC ENVIRONMENT; AQUEOUS SOLUTION; ARTICLE; DRUG DEGRADATION; DRUG HALF LIFE; DRUG INDUSTRY; EFFLUENT; ENVIRONMENTAL MONITORING; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHOTODEGRADATION; PHOTOLYSIS; QUANTUM YIELD; SEASONAL VARIATION; SEWAGE TREATMENT; SOLAR ENERGY; SUNLIGHT;

EID: 0037369490     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0045-6535(02)00769-5     Document Type: Article

References (35)

1. Ahrer, W., Scherwenk, E., Buchberger, W., 2001. Determination of drug residues in water by combination of liquid chromatography or capillary electrophoresis with electrospray mass spectrometry. J. Chromatogr. A 910, 69-78.
2. Buser, H.R., Müller, M., 1998. Occurrence of the pharmaceutical drug clofibric acid and the herbicide mecoprop in various Swiss lakes and in the North Sea. Environ. Sci. Technol. 32, 188-192.
3. Canonica, S., Jans, U., Stemmler, K., Hoigné, J., 1995. Transformation kinetics of phenol in water: photosensitization by dissolved natural organic material and aromatic ketones. Environ. Sci. Technol. 29, 1822-1831.
4. 2/UV. Estimation of kinetic parameters. In: Proceedings of the 12th Ozone World Congress of the International Ozone Assessment, Lille, May 1995, pp. 373-384.
5. Dulin, D., Mill, T., 1982. Development and evaluation of sunlight actinometers. Environ. Sci. Technol. 16, 815-820.
6. EPAOPPTS 835.2210-Fate, transport and transformation test guidelines: Direct photolysis rate in water by sunlight, 1996. United States Environmental Protection Agency, Washington, DC.
7. Frank, R., Klopffer, W., 1988. A convenient model and program for the assessment of abiotic degradation of chemicals in natural waters. Ecotoxicol. Environ. Saf. 17, 323-332.
8. Gao, H., Zepp, R.G., 1998. Factors influencing photoreactions of dissolved organic matter in a coastal river of the Southeastern United States. Environ. Sci. Technol. 32, 2940-2946.
9. Golet, E.M., Alder, A.C., Hartmann, A., Ternes, T., Giger, W., 2001. Trace determination of fluoroquinolone antibacterial agents in urban wastewater by solid-phase extraction and liquid chromatography with fluorescence detection. Anal. Chem. 73, 3632-3638.
10. Haag, W.R., Hoigné, J., 1986. Singlet oxygen in surface waters. 3 Photochemical formation and steady-state concentrations in various types of waters. Environ. Sci. Technol. 20, 341-348.
11. Heberer, T., Dünnbier, U., Reilich, C., Stan, H.-J., 1997. Detection of drugs and drug metabolites in groundwater samples of a drinking water treatment plant. Fresenius Envir. Bull. 6, 438-443.
12. Hartig, C., Storm, T., Jekel, M., 1999. Detection and identification of sulphonamide drugs in municipal wastewater by liquid chromatography coupled with electrospray ionisation tandem mass spectrometry. J. Chromatogr. A 854, 163-173.
13. Hirsch, R., Ternes, T., Haberer, K., Mehlich, A., Ballwanz, F., Kratz, K.-L., 1998. Determination of antibiotics in different water compartments via liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr. A 815, 213-223.
14. Hirsch, R., Ternes, T., Haberer, K., Kratz, K.-L., 1999. Occurrence of antibiotics in the aquatic environment. Sci. Total Environ. 225 (1-2), 108-118.
15. Johansson, M., Tysklind, M., 2001. The occurrence, transport and effects of antibiotics in the environment. Final report. SNV-Swedish Environmental Protection Agency.
16. Mack, J., Bolton, J.R., 1999. Photochemistry of nitrite and nitrate in aqueous solution: a review. J. Photochem. Photobiol. A: Chem. 128, 1-13.
17. Moore, D.E., Thomson, S.R., Zhen, D., Duke, C.C., 1990. Photochemical studies on the anti-inflammatory drug diclofenac. Photochem. Photobiol. 52 (4), 685-690.
18. Nicole, I., De Laat, J., Dorè, M., Duguet, J.P., Bonnel, C., 1990. Use of UV radiation in water treatment: measurement of photonic flux by hydrogen peroxide actinometry. Water Res. 24 (2), 157-168.
19. OECD (Organisation for Economic Co-operation and Development), 2000. Guidance document for testing of chemicals. Phototransformation of Chemicals in water - Direct and indirect photolysis. OECD Environmental Health and Safety Publication.
20. Öllers, Sj., Singer, H., Fässler, Ph., Müller, S.R., 2001. Simultaneous quantification of neutral and acidic pharmaceuticals and pesticides in low-ng/l level in surface and waste water. J. Chromatogr. A 911, 225-234.
21. Richardson, M.L., Bowron, J.M., 1985. The fate of pharmaceutical chemicals in the aquatic environment: A review. J. Pharm. Pharmacol. 37, 1-12.
22. Sacher, F., Lange, F.T., Brauch, H.-J., Blankenhorn, I., 2001. Pharmaceuticals in groundwaters. Analytical methods and results of a monitoring program in Baden, Württemberg, Germany. J. Chromatogr. A 938, 199-210.
23. Stan, H.J., Haberer, T., Linkerhägner, M., 1994. Occurrence of clofibric acid in aquatic system - is the use of human medical care the source of the contamination of surface, ground and drinking water? Vom Wasser 83, 57-68.
24. Stangroom, S.J., MacLeod, C.L., Lester, J.N., 1998. Photosensitized transformation of the herbicide 4-chloro-2-methylphenoxy acetic acid (MCPA) in water. Water Res. 32 (3), 623-632.
25. Ternes, T., 1998. Occurrence of drugs in German sewage treatment plants and rivers. Water Res. 32 (11), 3245-3260.
26. Ternes, T., Stumpf, M., Schuppert, B., Haberer, K., 1998a. Simultaneous determination of antiseptics and acidic drugs in sewage and river water. Vom Wasser 90, 295-309.
27. Ternes, T., Hirsch, R., Mueller, J., 1998b. Methods for the determination of neutral drugs as well as betablockers and β-sympathomimetics in aqueous matrices using GC/MS and LC/MS/MS. Fresenius J. Anal. Chem. 362, 329-340.
28. Waggott, A., 1981. Trace organic substances in the River Lee Great Britain. In: Cooper, W.J. (Ed.), Chemical Water Reuse, vol. 2. Ann Arbor Science, Ann Arbor, MI, pp. 55-99.
29. Watts, C.D., Crathorne, M., Fielding, M., Steel, C.P., 1983. Identification of non-volatile organics in water using field desorption mass spectrometry and high performance liquid chromatography. In: Angeletti, G. (Ed.), Analysis of Organic Micropollutants in Water. Reidel Publ. Corp., Dordrecht, pp. 120-131.
30. Zepp, R., 1989. US Environmental Protection Agency, College Station road, Athens, private communication.
31. Zepp, R.G., Cline, D.M., 1977. Rates of direct photolysis in aquatic environment. Environ. Sci. Technol. 11 (4), 359-366.
32. Zepp, R.G., Baughman, G.L., Schlotzhauer, P.F., 1981. Comparison of photochemical behaviour of various humic substances in water: I Sunlight induced reactions of aquatic pollutants photosensitized by humic substances. Chemosphere 10, 109-117.
33. Zepp, R.G., Schlotzauer, P.F., Sink, R.M., 1985. Photosensitized transformations involving electronic energy transfer in natural waters: role of humic substances. Environ. Sci. Technol. 19, 74-81.
34. Zepp, R.G., Hoigné, J., Bader, H., 1987. Nitrate-induced photooxidation of trace organic chemicals in water. Environ. Sci. Technol. 21, 443-450.
35. Zuccato, E., Calamari, D., Natangelo, M., Fanelli, R., 2000. Presence of therapeutic drugs in the environment. Lancet 355, 1789-1790.