Metabolism and excretion kinetics of 14C-labeled and non-labeled difloxacin in pigs after oral administration, and antimicrobial activity of manure containing difloxacin and its metabolites

Environmental Research

Volumn 109, Issue 3, 2009, Pages 225-231

  Sukul, Premasis ^a   Lamshöft, Marc ^a   Kusari, Souvik ^a   Zühlke, Sebastian ^a   Spiteller, Michael ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

Author keywords

Accurate mass measurement; LC MS MS; Radiochemical methods; Veterinary drug

Indexed keywords

CARBON 14; DIFLOXACIN; NORDIFLOXACIN;

ANTIMICROBIAL ACTIVITY; CARBON ISOTOPE; DRUG; EXCRETION; KINETICS; MANURE; MASS SPECTROMETRY; METABOLISM; METABOLITE; PIG; RADIOACTIVITY;

ANIMAL EXPERIMENT; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; CHROMATOGRAPHY; CONCENTRATION PROCESS; CONTROLLED STUDY; DRUG ELIMINATION; DRUG EXCRETION; DRUG METABOLISM; ENVIRONMENTAL MONITORING; IN VITRO STUDY; INTERMETHOD COMPARISON; MANURE; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SWINE;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; CALIBRATION; CARBON RADIOISOTOPES; CIPROFLOXACIN; ENVIRONMENTAL POLLUTANTS; MALE; MANURE; MICROBIAL SENSITIVITY TESTS; REFERENCE STANDARDS; SWINE;

SUIDAE;

EID: 61749101241     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2008.12.007     Document Type: Article

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