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Volumn 6, Issue 2, 2010, Pages 282-296

A transcriptional roadmap to the induction of pluripotency in somatic cells

Author keywords

Cellular reprogramming; EMT; ES cells; Gene regulatory networks; iPS cells; MET; PiPSC; Pluripotency; Self renewal

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CYTOLOGY; EMBRYONIC STEM CELL; EPITHELIUM CELL; GENETICS; HUMAN; MESODERM; METABOLISM; PATHOLOGY; PHYSIOLOGY; PLURIPOTENT STEM CELL;

EID: 77953916259     PISSN: 15508943     EISSN: 15586804     Source Type: Journal    
DOI: 10.1007/s12015-010-9137-2     Document Type: Article
Times cited : (63)

References (69)
  • 2
    • 0035957754 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer
    • Wakayama, T., Tabar, V., Rodriguez, I., Perry, A. C., Studer, L., & Mombaerts, P. (2001). Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science, 292(5517), 740-743.
    • (2001) Science , vol.292 , Issue.5517 , pp. 740-743
    • Wakayama, T.1    Tabar, V.2    Rodriguez, I.3    Perry, A.C.4    Studer, L.5    Mombaerts, P.6
  • 3
    • 23944457397 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
    • Cowan, C. A., Atienza, J., Melton, D. A., & Eggan, K. (2005). Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science, 309(5739), 1369-1373.
    • (2005) Science , vol.309 , Issue.5739 , pp. 1369-1373
    • Cowan, C.A.1    Atienza, J.2    Melton, D.A.3    Eggan, K.4
  • 4
    • 28644443829 scopus 로고    scopus 로고
    • Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells
    • Taranger, C. K., Noer, A., Sørensen, A. L., Håkelien, A. M., Boquest, A. C., & Collas, P. (2005). Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. Molecular Biology of the Cell, 16(12), 5719-5735.
    • (2005) Molecular Biology of the Cell , vol.16 , Issue.12 , pp. 5719-5735
    • Taranger, C.K.1    Noer, A.2    Sørensen, A.L.3    Håkelien, A.M.4    Boquest, A.C.5    Collas, P.6
  • 5
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi, K., & Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126(4), 663-676.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 6
    • 35148845584 scopus 로고    scopus 로고
    • Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
    • Meissner, A., Wernig, M., & Jaenisch, R. (2007). Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nature Biotechnology, 25(10), 1177-1181.
    • (2007) Nature Biotechnology , vol.25 , Issue.10 , pp. 1177-1181
    • Meissner, A.1    Wernig, M.2    Jaenisch, R.3
  • 7
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., et al. (2007). Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors. Cell, 131(5), 861-872.
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 8
    • 36749043230 scopus 로고    scopus 로고
    • Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
    • Yu, J., Vodyanik, M. A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J. L., Tian, S., et al. (2007). Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells. Science, 318(5858), 1917-1920.
    • (2007) Science , vol.318 , Issue.5858 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3    Antosiewicz-Bourget, J.4    Frane, J.L.5    Tian, S.6
  • 9
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park, I. H., Zhao, R., West, J. A., Yabuuchi, A., Huo, H., Ince, T. A., et al. (2008). Reprogramming of human somatic cells to pluripotency with defined factors. Nature, 451(7175), 141-146.
    • (2008) Nature , vol.451 , Issue.7175 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3    Yabuuchi, A.4    Huo, H.5    Ince, T.A.6
  • 10
    • 55749089875 scopus 로고    scopus 로고
    • Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
    • Aasen, T., Raya, A., Barrero, M. J., Garreta, E., Consiglio, A., Gonzalez, F., et al. (2008). Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nature Biotechnology, 26(11), 1276-1284.
    • (2008) Nature Biotechnology , vol.26 , Issue.11 , pp. 1276-1284
    • Aasen, T.1    Raya, A.2    Barrero, M.J.3    Garreta, E.4    Consiglio, A.5    Gonzalez, F.6
  • 12
    • 50149098605 scopus 로고    scopus 로고
    • Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons
    • Dimos, J. T., Rodolfa, K. T., Niakan, K. K., Weisenthal, L. M., Mitsumoto, H., Chung, W., et al. (2008). Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science, 321(5893), 1218-1221.
    • (2008) Science , vol.321 , Issue.5893 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3    Weisenthal, L.M.4    Mitsumoto, H.5    Chung, W.6
  • 13
    • 50549089957 scopus 로고    scopus 로고
    • Disease-Specific Induced Pluripotent Stem Cells
    • Park, I. H., Arora, N., Huo, H., Maherali, N., Ahfeldt, T., Shimamura, A., et al. (2008). Disease-Specific Induced Pluripotent Stem Cells. Cell, 134(5), 877-886.
    • (2008) Cell , vol.134 , Issue.5 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3    Maherali, N.4    Ahfeldt, T.5    Shimamura, A.6
  • 14
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • Ebert, A. D., Yu, J., Rose, F. F., Jr., Mattis, V. B., Lorson, C. L., Thomson, J. A., et al. (2009). Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature, 457(7227), 277-280.
    • (2009) Nature , vol.457 , Issue.7227 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose Jr., F.F.3    Mattis, V.B.4    Lorson, C.L.5    Thomson, J.A.6
  • 15
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
    • Soldner, F., Hockemeyer, D., Beard, C., Gao, Q., Bell, G. W., Cook, E. G., et al. (2009). Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell, 136(5), 964-977.
    • (2009) Cell , vol.136 , Issue.5 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3    Gao, Q.4    Bell, G.W.5    Cook, E.G.6
  • 16
    • 67650095306 scopus 로고    scopus 로고
    • Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
    • Raya, A., Rodríguez-Pizà, I., Guenechea, G., Vassena, R., Navarro, S., Barrero, M. J., et al. (2009). Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature, 460(7251), 53-59.
    • (2009) Nature , vol.460 , Issue.7251 , pp. 53-59
    • Raya, A.1    Rodríguez-Pizà, I.2    Guenechea, G.3    Vassena, R.4    Navarro, S.5    Barrero, M.J.6
  • 18
    • 64149118087 scopus 로고    scopus 로고
    • Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells
    • Zhang, D., Jiang, W., Liu, M., Sui, X., Yin, X., Chen, S., et al. (2009). Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Research, 19(4), 429-438.
    • (2009) Cell Research , vol.19 , Issue.4 , pp. 429-438
    • Zhang, D.1    Jiang, W.2    Liu, M.3    Sui, X.4    Yin, X.5    Chen, S.6
  • 19
    • 65249102249 scopus 로고    scopus 로고
    • Hematopoietic and endothelial differentiation of human induced pluripotent stem cells
    • Choi, K. D., Yu, J., Smuga-Otto, K., Salvagiotto, G., Rehrauer, W., Vodyanik, M., et al. (2009). Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. Stem Cells, 27(3), 559-567.
    • (2009) Stem Cells , vol.27 , Issue.3 , pp. 559-567
    • Choi, K.D.1    Yu, J.2    Smuga-Otto, K.3    Salvagiotto, G.4    Rehrauer, W.5    Vodyanik, M.6
  • 20
    • 61749094336 scopus 로고    scopus 로고
    • Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells
    • Taura, D., Noguchi, M., Sone, M., Hosoda, K., Mori, E., Okada, Y., et al. (2009). Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. FEBS Letters, 583(6), 1029-1033.
    • (2009) FEBS Letters , vol.583 , Issue.6 , pp. 1029-1033
    • Taura, D.1    Noguchi, M.2    Sone, M.3    Hosoda, K.4    Mori, E.5    Okada, Y.6
  • 21
    • 62149125434 scopus 로고    scopus 로고
    • Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
    • Chambers, S. M., Fasano, C. A., Papapetrou, E. P., Tomishima, M., Sadelain, M., & Studer, L. (2009). Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nature Biotechnology, 27(3), 275-280.
    • (2009) Nature Biotechnology , vol.27 , Issue.3 , pp. 275-280
    • Chambers, S.M.1    Fasano, C.A.2    Papapetrou, E.P.3    Tomishima, M.4    Sadelain, M.5    Studer, L.6
  • 22
    • 70449534874 scopus 로고    scopus 로고
    • Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells
    • Song, Z., Cai, J., Liu, Y., Zhao, D., Yong, J., Duo, S., et al. (2009). Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Research, 19(11), 1233-1242.
    • (2009) Cell Research , vol.19 , Issue.11 , pp. 1233-1242
    • Song, Z.1    Cai, J.2    Liu, Y.3    Zhao, D.4    Yong, J.5    Duo, S.6
  • 23
    • 73449100783 scopus 로고    scopus 로고
    • Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells
    • Si-Tayeb, K., Noto, F. K., Nagaoka, M., Li, J., Battle, M. A., Duris, C., et al. (2010). Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology, 51(1), 297-305.
    • (2010) Hepatology , vol.51 , Issue.1 , pp. 297-305
    • Si-Tayeb, K.1    Noto, F.K.2    Nagaoka, M.3    Li, J.4    Battle, M.A.5    Duris, C.6
  • 24
    • 73449100456 scopus 로고    scopus 로고
    • Generation of functional human hepatic endoderm from human induced pluripotent stem cells
    • Sullivan, G. J., Hay, D. C., Park, I. H., Fletcher, J., Hannoun, Z., Payne, C. M., et al. (2010). Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology, 51(1), 329-335.
    • (2010) Hepatology , vol.51 , Issue.1 , pp. 329-335
    • Sullivan, G.J.1    Hay, D.C.2    Park, I.H.3    Fletcher, J.4    Hannoun, Z.5    Payne, C.M.6
  • 25
    • 48749109906 scopus 로고    scopus 로고
    • Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts
    • Mali, P., Ye, Z., Hommond, H. H., Yu, X., Lin, J., Chen, G., et al. (2008). Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal Fibroblasts. Stem Cells, 26(8), 1998-2005.
    • (2008) Stem Cells , vol.26 , Issue.8 , pp. 1998-2005
    • Mali, P.1    Ye, Z.2    Hommond, H.H.3    Yu, X.4    Lin, J.5    Chen, G.6
  • 26
    • 54949136146 scopus 로고    scopus 로고
    • Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation
    • Zhao, Y., Yin, X., Qin, H., Zhu, F., Liu, H., Yang, W., et al. (2008). Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation. Cell Stem Cell, 3(5), 475-479.
    • (2008) Cell Stem Cell , vol.3 , Issue.5 , pp. 475-479
    • Zhao, Y.1    Yin, X.2    Qin, H.3    Zhu, F.4    Liu, H.5    Yang, W.6
  • 27
    • 69349100179 scopus 로고    scopus 로고
    • Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
    • Hong, H., Takahashi, K., Ichisaka, T., Aoi, T., Kanagawa, O., Nakagawa, M., et al. (2009). Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature, 460(7259), 1132-1135.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1132-1135
    • Hong, H.1    Takahashi, K.2    Ichisaka, T.3    Aoi, T.4    Kanagawa, O.5    Nakagawa, M.6
  • 28
    • 69349103956 scopus 로고    scopus 로고
    • The Ink4/Arf locus is a barrier for iPS cell reprogramming
    • Li, H., Collado, M., Villasante, A., Strati, K., Ortega, S., Cañamero, M., et al. (2009). The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature, 460(7259), 1136-1139.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1136-1139
    • Li, H.1    Collado, M.2    Villasante, A.3    Strati, K.4    Ortega, S.5    Cañamero, M.6
  • 29
    • 69349100455 scopus 로고    scopus 로고
    • Linking the p53 tumour suppressor pathway to somatic cell reprogramming
    • Kawamura, T., Suzuki, J., Wang, Y. V., Menendez, S., Morera, L. B., Raya, A., et al. (2009). Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature, 460(7259), 1140-1144.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1140-1144
    • Kawamura, T.1    Suzuki, J.2    Wang, Y.V.3    Menendez, S.4    Morera, L.B.5    Raya, A.6
  • 30
    • 69349098273 scopus 로고    scopus 로고
    • Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
    • Utikal, J., Polo, J. M., Stadtfeld, M., Maherali, N., Kulalert, W., Walsh, R. M., et al. (2009). Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature, 460(7259), 1145-1148.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1145-1148
    • Utikal, J.1    Polo, J.M.2    Stadtfeld, M.3    Maherali, N.4    Kulalert, W.5    Walsh, R.M.6
  • 31
    • 69349094006 scopus 로고    scopus 로고
    • A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
    • Marión, R. M., Strati, K., Li, H., Murga, M., Blanco, R., Ortega, S., et al. (2009). A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature, 460(7259), 1149-1153.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1149-1153
    • Marión, R.M.1    Strati, K.2    Li, H.3    Murga, M.4    Blanco, R.5    Ortega, S.6
  • 32
    • 46449094276 scopus 로고    scopus 로고
    • Dissecting direct reprogramming through integrative genomic analysis
    • Mikkelsen, T. S., Hanna, J., Zhang, X., Ku, M., Wernig, M., Schorderet, P., et al. (2008). Dissecting direct reprogramming through integrative genomic analysis. Nature, 454(7200), 49-55.
    • (2008) Nature , vol.454 , Issue.7200 , pp. 49-55
    • Mikkelsen, T.S.1    Hanna, J.2    Zhang, X.3    Ku, M.4    Wernig, M.5    Schorderet, P.6
  • 33
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • Huangfu, D., Maehr, R., Guo, W., Eijkelenboom, A., Snitow, M., Chen, A. E., et al. (2008). Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nature Biotechnology, 26(7), 795-797.
    • (2008) Nature Biotechnology , vol.26 , Issue.7 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3    Eijkelenboom, A.4    Snitow, M.5    Chen, A.E.6
  • 34
    • 54949115497 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds
    • Shi, Y., Desponts, C., Do, J. T., Hahm, H. S., Schöler, H. R., & Ding, S. (2008). Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds. Cell Stem Cell, 3(5), 568-574.
    • (2008) Cell Stem Cell , vol.3 , Issue.5 , pp. 568-574
    • Shi, Y.1    Desponts, C.2    Do, J.T.3    Hahm, H.S.4    Schöler, H.R.5    Ding, S.6
  • 35
    • 44349103591 scopus 로고    scopus 로고
    • A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells
    • Shi, Y., Do, J. T., Desponts, C., Hahm, H. S., Schöler, H. R., & Ding, S. (2008). A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells. Cell Stem Cell, 2(6), 525-528.
    • (2008) Cell Stem Cell , vol.2 , Issue.6 , pp. 525-528
    • Shi, Y.1    Do, J.T.2    Desponts, C.3    Hahm, H.S.4    Schöler, H.R.5    Ding, S.6
  • 37
    • 70350536767 scopus 로고    scopus 로고
    • A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog
    • Ichida, J. K., Blanchard, J., Lam, K., Son, E. Y., Chung, J. E., Egli, D., et al. (2009). A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell, 5(5), 491-503.
    • (2009) Cell Stem Cell , vol.5 , Issue.5 , pp. 491-503
    • Ichida, J.K.1    Blanchard, J.2    Lam, K.3    Son, E.Y.4    Chung, J.E.5    Egli, D.6
  • 38
    • 73049112178 scopus 로고    scopus 로고
    • Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
    • Esteban, M. A., Wang, T., Qin, B., Yang, J., Qin, D., Cai, J., et al. (2010). Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell, 6(1), 71-79.
    • (2010) Cell Stem Cell , vol.6 , Issue.1 , pp. 71-79
    • Esteban, M.A.1    Wang, T.2    Qin, B.3    Yang, J.4    Qin, D.5    Cai, J.6
  • 39
    • 55749104227 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
    • Huangfu, D., Osafune, K., Maehr, R., Guo, W., Eijkelenboom, A., Chen, S., et al. (2008). Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nature Biotechnology, 26(11), 1269-1275.
    • (2008) Nature Biotechnology , vol.26 , Issue.11 , pp. 1269-1275
    • Huangfu, D.1    Osafune, K.2    Maehr, R.3    Guo, W.4    Eijkelenboom, A.5    Chen, S.6
  • 40
    • 70350732790 scopus 로고    scopus 로고
    • A chemical platform for improved induction of human iPSCs
    • Lin, T., Ambasudhan, R., Yuan, X., Li, W., Hilcove, S., Abujarour, R., et al. (2009). A chemical platform for improved induction of human iPSCs. Nature Methods, 6(11), 805-808.
    • (2009) Nature Methods , vol.6 , Issue.11 , pp. 805-808
    • Lin, T.1    Ambasudhan, R.2    Yuan, X.3    Li, W.4    Hilcove, S.5    Abujarour, R.6
  • 41
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa, M., Koyanagi, M., Tanabe, K., Takahashi, K., Ichisaka, T., Aoi, T., et al. (2008). Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nature Biotechnology, 26(1), 101-106.
    • (2008) Nature Biotechnology , vol.26 , Issue.1 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3    Takahashi, K.4    Ichisaka, T.5    Aoi, T.6
  • 42
    • 55749089875 scopus 로고    scopus 로고
    • Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
    • Aasen, T., Raya, A., Barrero, M. J., Garreta, E., Consiglio, A., Gonzalez, F., et al. (2008). Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nature Biotechnology, 26(11), 1276-1284.
    • (2008) Nature Biotechnology , vol.26 , Issue.11 , pp. 1276-1284
    • Aasen, T.1    Raya, A.2    Barrero, M.J.3    Garreta, E.4    Consiglio, A.5    Gonzalez, F.6
  • 43
    • 70350380887 scopus 로고    scopus 로고
    • Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
    • Utikal, J., Maherali, N., Kulalert, W., & Hochedlinger, K. (2009). Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. Journal of Cell Science, 122(Pt 19), 3502-3510.
    • (2009) Journal of Cell Science , vol.122 , Issue.Pt 19 , pp. 3502-3510
    • Utikal, J.1    Maherali, N.2    Kulalert, W.3    Hochedlinger, K.4
  • 44
    • 70349687407 scopus 로고    scopus 로고
    • Direct reprogramming of human neural stem cells by OCT4
    • Kim, J. B., Greber, B., Araúzo-Bravo, M. J., Meyer, J., Park, K. I., Zaehres, H., et al. (2009). Direct reprogramming of human neural stem cells by OCT4. Nature, 461(7264), 649-643.
    • (2009) Nature , vol.461 , Issue.7264 , pp. 649-643
    • Kim, J.B.1    Greber, B.2    Araúzo-Bravo, M.J.3    Meyer, J.4    Park, K.I.5    Zaehres, H.6
  • 45
    • 77149126770 scopus 로고    scopus 로고
    • Tsai, S. Y., Clavel, C., Kim, S., Ang, Y. S., Grisanti, L., Lee, D. F., et al. (2010). Oct4 and Klf4 Reprogram Dermal Papilla Cells into Induced Pluripotent Stem Cells. Stem Cells, [Epub ahead of print].
  • 46
    • 70450265981 scopus 로고    scopus 로고
    • Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
    • Fusaki, N., Ban, H., Nishiyama, A., Saeki, K., & Hasegawa, M. (2009). Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proceedings of the Japan Academy, Series B, Physical and Biological Sciences, 85(8), 348-362.
    • (2009) Proceedings of the Japan Academy, Series B, Physical and Biological Sciences , vol.85 , Issue.8 , pp. 348-362
    • Fusaki, N.1    Ban, H.2    Nishiyama, A.3    Saeki, K.4    Hasegawa, M.5
  • 47
    • 72849137462 scopus 로고    scopus 로고
    • Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells
    • Zhou, W., & Freed, C. R. (2009). Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem cells, 27(11), 2667-2674.
    • (2009) Stem Cells , vol.27 , Issue.11 , pp. 2667-2674
    • Zhou, W.1    Freed, C.R.2
  • 48
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita, K., Nakagawa, M., Hyenjong, H., Ichisaka, T., & Yamanaka, S. (2008). Generation of mouse induced pluripotent stem cells without viral vectors. Science, 322(5903), 949-953.
    • (2008) Science , vol.322 , Issue.5903 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 50
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • Yu, J., Hu, K., Smuga-Otto, K., Tian, S., Stewart, R., Slukvin, I. I., et al. (2009). Human induced pluripotent stem cells free of vector and transgene sequences. Science, 324(5928), 797-801.
    • (2009) Science , vol.324 , Issue.5928 , pp. 797-801
    • Yu, J.1    Hu, K.2    Smuga-Otto, K.3    Tian, S.4    Stewart, R.5    Slukvin, I.I.6
  • 51
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen, K., Michael, I. P., Mohseni, P., Desai, R., Mileikovsky, M., Hämäläinen, R., et al. (2009). piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature, 458(7239), 766-770.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3    Desai, R.4    Mileikovsky, M.5    Hämäläinen, R.6
  • 52
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji, K., Norrby, K., Paca, A., Mileikovsky, M., Mohseni, P., & Woltjen, K. (2009). Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature, 458(7239), 771-775.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 53
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou, H., Wu, S., Joo, J. Y., Zhu, S., Han, D. W., Lin, T., et al. (2009). Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell, 4(5), 381-384.
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3    Zhu, S.4    Han, D.W.5    Lin, T.6
  • 54
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim, D., Kim, C. H., Moon, J. I., Chung, Y. G., Chang, M. Y., Han, B. S., et al. (2009). Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell, 4(6), 472-476.
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3    Chung, Y.G.4    Chang, M.Y.5    Han, B.S.6
  • 55
    • 67649222358 scopus 로고    scopus 로고
    • Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures
    • Chin, M. H., Mason, M. J., Xie, W., Volinia, S., Singer, M., Peterson, C., et al. (2009). Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell, 5(1), 111-123.
    • (2009) Cell Stem Cell , vol.5 , Issue.1 , pp. 111-123
    • Chin, M.H.1    Mason, M.J.2    Xie, W.3    Volinia, S.4    Singer, M.5    Peterson, C.6
  • 56
    • 70349445082 scopus 로고    scopus 로고
    • Transcriptional signature and memory retention of human-induced pluripotent stem cells
    • Marchetto, M. C., Yeo, G. W., Kainohana, O., Marsala, M., Gage, F. H., & Muotri, A. R. (2009). Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS ONE, 4(9), e7076.
    • (2009) PLoS ONE , vol.4 , Issue.9
    • Marchetto, M.C.1    Yeo, G.W.2    Kainohana, O.3    Marsala, M.4    Gage, F.H.5    Muotri, A.R.6
  • 57
    • 50849142559 scopus 로고    scopus 로고
    • A high-efficiency system for the generation and study of human induced pluripotent stem cells
    • Maherali, N., Ahfeldt, T., Rigamonti, A., Utikal, J., Cowan, C., & Hochedlinger, K. (2008). A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell, 3(3), 340-345.
    • (2008) Cell Stem Cell , vol.3 , Issue.3 , pp. 340-345
    • Maherali, N.1    Ahfeldt, T.2    Rigamonti, A.3    Utikal, J.4    Cowan, C.5    Hochedlinger, K.6
  • 58
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner, F., Hockemeyer, D., Beard, C., Gao, Q., Bell, G. W., Cook, E. G., et al. (2009). Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell, 136(5), 964-977.
    • (2009) Cell , vol.136 , Issue.5 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3    Gao, Q.4    Bell, G.W.5    Cook, E.G.6
  • 59
    • 34250729138 scopus 로고    scopus 로고
    • Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
    • Rinn, J. L., Kertesz, M., Wang, J. K., Squazzo, S. L., Xu, X., Brugmann, S. A., et al. (2007). Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell, 129(7), 1311-1323.
    • (2007) Cell , vol.129 , Issue.7 , pp. 1311-1323
    • Rinn, J.L.1    Kertesz, M.2    Wang, J.K.3    Squazzo, S.L.4    Xu, X.5    Brugmann, S.A.6
  • 60
    • 66149160608 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs promote induced pluripotency
    • Judson, R. L., Babiarz, J. E., Venere, M., & Blelloch, R. (2009). Embryonic stem cell-specific microRNAs promote induced pluripotency. Nature Biotechnology, 27(5), 459-461.
    • (2009) Nature Biotechnology , vol.27 , Issue.5 , pp. 459-461
    • Judson, R.L.1    Babiarz, J.E.2    Venere, M.3    Blelloch, R.4
  • 62
    • 33846917472 scopus 로고    scopus 로고
    • Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
    • Babaie, Y., Herwig, R., Greber, B., Brink, T. C., Wruck, W., Groth, D., et al. (2007). Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells, 25(2), 500-510.
    • (2007) Stem Cells , vol.25 , Issue.2 , pp. 500-510
    • Babaie, Y.1    Herwig, R.2    Greber, B.3    Brink, T.C.4    Wruck, W.5    Groth, D.6
  • 63
    • 67949100470 scopus 로고    scopus 로고
    • In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach
    • Chavez, L., Bais, A. S., Vingron, M., Lehrach, H., Adjaye, J., & Herwig, R. (2009). In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach. BMC Genomics, 10, 314.
    • (2009) BMC Genomics , vol.10 , pp. 314
    • Chavez, L.1    Bais, A.S.2    Vingron, M.3    Lehrach, H.4    Adjaye, J.5    Herwig, R.6
  • 64
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-Mesenchymal Transitions in Development and Disease
    • Thiery, J. P., Acloque, H., Huang, R. Y., & Nieto, M. A. (2009). Epithelial-Mesenchymal Transitions in Development and Disease. Cell, 139(5), 871-890.
    • (2009) Cell , vol.139 , Issue.5 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 65
    • 33845619576 scopus 로고    scopus 로고
    • Ullmann, U., In't Veld, P., Gilles, C., Sermon, K., De Rycke, M., van de Velde, H., et al. Epithelial-mesenchymal transition process in human embryonic stem cells cultured in feeder-free conditions. Mol Hum Reprod, 13 (1), 21-32.
  • 66
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery, J. P., & Sleeman, J. P. (2006). Complex networks orchestrate epithelial-mesenchymal transitions. Nature Reviews Molecular Cell Biology, 7(2), 131-142.
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 67
    • 70349165716 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic
    • Voulgari, A., & Pintzas, A. (2009). Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochimica et Biophysica Acta, 1796(2), 75-90.
    • (2009) Biochimica Et Biophysica Acta , vol.1796 , Issue.2 , pp. 75-90
    • Voulgari, A.1    Pintzas, A.2
  • 68
    • 57449090247 scopus 로고    scopus 로고
    • Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity
    • Greber, B., Lehrach, H., & Adjaye, J. (2008). Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity. Stem Cells and Development, 17(6), 1065-1077.
    • (2008) Stem Cells and Development , vol.17 , Issue.6 , pp. 1065-1077
    • Greber, B.1    Lehrach, H.2    Adjaye, J.3
  • 69
    • 4544341015 scopus 로고    scopus 로고
    • Smyth, G. K. (2004). Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Statistical Applications in Genetics and Molecular Biology, Volume 3.


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