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Volumn 39, Issue 8, 2016, Pages 1100-1113

Myofibroblasts and inflammatory cells as players of cardiac fibrosis

Author keywords

Cardiac fibrosis; Inflammation; Myocardial infarction; Myofibroblasts; Signaling molecules

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANGIOTENSIN II; BIOLOGICAL MARKER; CALVASCULIN; COLLAGEN RECEPTOR; COLLAGEN TYPE 1; COLLAGEN TYPE 1 ALPHA 1; DISCOIDIN; DISCOIDIN DOMAIN RECEPTOR 2; MYOCARDIN; MYOCARDIN RELATED TRANSCRIPTION FACTOR; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN TYROSINE KINASE; SERUM RESPONSE FACTOR; THY 1 ANTIGEN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 21; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG; VIMENTIN; COLLAGEN;

EID: 84981485012     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-016-0809-6     Document Type: Review
Times cited : (53)

References (83)
  • 2
    • 84980015797 scopus 로고    scopus 로고
    • Matters of context guide future research in TGFβ superfamily signaling
    • PID: 26486175
    • Akhurst RJ, Padgett RW (2015) Matters of context guide future research in TGFβ superfamily signaling. Sci Signal 8:re10
    • (2015) Sci Signal , vol.8 , pp. re10
    • Akhurst, R.J.1    Padgett, R.W.2
  • 4
    • 34548423254 scopus 로고    scopus 로고
    • Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse
    • COI: 1:CAS:528:DC%2BD2sXhtVOqtrnM, PID: 17604329
    • Banerjee I, Fuseler JW, Price RL, Borg TK, Baudino TA (2007) Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am J Physiol Heart Circ Physiol 293:H1883–H1891
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. H1883-H1891
    • Banerjee, I.1    Fuseler, J.W.2    Price, R.L.3    Borg, T.K.4    Baudino, T.A.5
  • 5
    • 84897508169 scopus 로고    scopus 로고
    • Aging and cardiac fibrosis
    • PID: 21837283
    • Biernacka A, Frangogiannis NG (2011) Aging and cardiac fibrosis. Aging Dis 2:158–173
    • (2011) Aging Dis , vol.2 , pp. 158-173
    • Biernacka, A.1    Frangogiannis, N.G.2
  • 7
    • 84886731169 scopus 로고    scopus 로고
    • Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease
    • COI: 1:CAS:528:DC%2BC3sXhsl2gsr%2FL, PID: 24140724
    • Braitsch CM, Kanisicak O, van Berlo JH, Molkentin JD, Yutzey KE (2013) Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease. J Mol Cell Cardiol 65:108–119
    • (2013) J Mol Cell Cardiol , vol.65 , pp. 108-119
    • Braitsch, C.M.1    Kanisicak, O.2    van Berlo, J.H.3    Molkentin, J.D.4    Yutzey, K.E.5
  • 8
    • 0031194295 scopus 로고    scopus 로고
    • Angiotensin II stimulated expression of transforming growth factor-beta1 in cardiac fibroblasts and myofibroblasts
    • COI: 1:CAS:528:DyaK2sXltVOqsrs%3D, PID: 9236148
    • Campbell SE, Katwa LC (1997) Angiotensin II stimulated expression of transforming growth factor-beta1 in cardiac fibroblasts and myofibroblasts. J Mol Cell Cardiol 29:1947–1958
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 1947-1958
    • Campbell, S.E.1    Katwa, L.C.2
  • 9
    • 58149500135 scopus 로고    scopus 로고
    • Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart
    • COI: 1:CAS:528:DC%2BD1MXhtVOiurk%3D, PID: 19011041
    • Chao W (2009) Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart. Am J Physiol Heart Circ Physiol 296:H1–H12
    • (2009) Am J Physiol Heart Circ Physiol , vol.296 , pp. H1-H12
    • Chao, W.1
  • 10
    • 84879383428 scopus 로고    scopus 로고
    • Progenitor cells identified by PDGFR-alpha expression in the developing and diseased human heart
    • COI: 1:CAS:528:DC%2BC3sXpslCiu7c%3D, PID: 23391309
    • Chong JJ, Reinecke H, Iwata M, Torok-Storb B, Stempien-Otero A, Murry CE (2013) Progenitor cells identified by PDGFR-alpha expression in the developing and diseased human heart. Stem Cells Dev 22:1932–1943
    • (2013) Stem Cells Dev , vol.22 , pp. 1932-1943
    • Chong, J.J.1    Reinecke, H.2    Iwata, M.3    Torok-Storb, B.4    Stempien-Otero, A.5    Murry, C.E.6
  • 11
    • 84938914288 scopus 로고    scopus 로고
    • Adenosine modulates NR4A orphan nuclear receptors to attenuate hyperinflammatory responses in monocytic cells
    • COI: 1:CAS:528:DC%2BC2MXht12gtrfO, PID: 26150530
    • Crean D, Cummins EP, Bahar B, Mohan H, McMorrow JP, Murphy EP (2015) Adenosine modulates NR4A orphan nuclear receptors to attenuate hyperinflammatory responses in monocytic cells. J Immunol 195:1436–1448
    • (2015) J Immunol , vol.195 , pp. 1436-1448
    • Crean, D.1    Cummins, E.P.2    Bahar, B.3    Mohan, H.4    McMorrow, J.P.5    Murphy, E.P.6
  • 12
    • 84867732495 scopus 로고    scopus 로고
    • A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo
    • COI: 1:CAS:528:DC%2BC38XhsValsLvM, PID: 23022034
    • Davis J, Burr AR, Davis GF, Birnbaumer L, Molkentin JD (2012) A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Dev Cell 23:705–715
    • (2012) Dev Cell , vol.23 , pp. 705-715
    • Davis, J.1    Burr, A.R.2    Davis, G.F.3    Birnbaumer, L.4    Molkentin, J.D.5
  • 13
    • 84899045255 scopus 로고    scopus 로고
    • Cell–cell interaction in the heart via Wnt/β-catenin pathway after cardiac injury
    • COI: 1:CAS:528:DC%2BC2cXmsVKhsb4%3D, PID: 24591151
    • Deb A (2014) Cell–cell interaction in the heart via Wnt/β-catenin pathway after cardiac injury. Cardiovasc Res 102:214–223
    • (2014) Cardiovasc Res , vol.102 , pp. 214-223
    • Deb, A.1
  • 15
    • 84864722077 scopus 로고    scopus 로고
    • Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury
    • COI: 1:CAS:528:DC%2BC38XhtFWmt73I, PID: 22842476
    • Dulauroy S, Di Carlo SE, Langa F, Eberl G, Peduto L (2012) Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury. Nat Med 18:1262–1270
    • (2012) Nat Med , vol.18 , pp. 1262-1270
    • Dulauroy, S.1    Di Carlo, S.E.2    Langa, F.3    Eberl, G.4    Peduto, L.5
  • 16
    • 0029117348 scopus 로고
    • What can be learned from intermediate filament gene regulation in the mouse embryo
    • COI: 1:CAS:528:DyaK2MXnvV2qu74%3D, PID: 7577435
    • Duprey P, Paulin D (1995) What can be learned from intermediate filament gene regulation in the mouse embryo. Int J Dev Biol 39:443–457
    • (1995) Int J Dev Biol , vol.39 , pp. 443-457
    • Duprey, P.1    Paulin, D.2
  • 18
    • 84904401883 scopus 로고    scopus 로고
    • Origin and functions of tissue macrophages
    • COI: 1:CAS:528:DC%2BC2cXhtFOrsLnE, PID: 25035951
    • Epelman S, Lavine KJ, Randolph GJ (2014) Origin and functions of tissue macrophages. Immunity 41:21–35
    • (2014) Immunity , vol.41 , pp. 21-35
    • Epelman, S.1    Lavine, K.J.2    Randolph, G.J.3
  • 19
    • 84952911887 scopus 로고    scopus 로고
    • Epicardium-derived fibroblasts in heart development and disease
    • COI: 1:CAS:528:DC%2BC28XjtFGmsA%3D%3D, PID: 26718723
    • Fang M, Xiang FL, Braitsch CM, Yutzey KE (2016) Epicardium-derived fibroblasts in heart development and disease. J Mol Cell Cardiol 91:23–27
    • (2016) J Mol Cell Cardiol , vol.91 , pp. 23-27
    • Fang, M.1    Xiang, F.L.2    Braitsch, C.M.3    Yutzey, K.E.4
  • 20
    • 84953313607 scopus 로고    scopus 로고
    • The crossroads of inflammation, fibrosis, and arrhythmia following myocardial infarction
    • COI: 1:CAS:528:DC%2BC28XmslKjtQ%3D%3D, PID: 26739214
    • Francis Stuart SD, De Jesus NM, Lindsey ML, Ripplinger CM (2016) The crossroads of inflammation, fibrosis, and arrhythmia following myocardial infarction. J Mol Cell Cardiol 91:114–122
    • (2016) J Mol Cell Cardiol , vol.91 , pp. 114-122
    • Francis Stuart, S.D.1    De Jesus, N.M.2    Lindsey, M.L.3    Ripplinger, C.M.4
  • 21
    • 84899090049 scopus 로고    scopus 로고
    • Cardiac macrophages and their role in ischaemic heart disease
    • COI: 1:CAS:528:DC%2BC2cXmsVKhtr0%3D, PID: 24501331
    • Frantz S, Nahrendorf M (2014) Cardiac macrophages and their role in ischaemic heart disease. Cardiovasc Res 102:240–248
    • (2014) Cardiovasc Res , vol.102 , pp. 240-248
    • Frantz, S.1    Nahrendorf, M.2
  • 23
    • 84955612078 scopus 로고    scopus 로고
    • Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease
    • PID: 27339799
    • Gourdie RG, Dimmeler S, Kohl P (2016) Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease. Nat Rev Drug Discov. doi:10.1038/nrd.2016.89
    • (2016) Nat Rev Drug Discov
    • Gourdie, R.G.1    Dimmeler, S.2    Kohl, P.3
  • 24
    • 84947751546 scopus 로고    scopus 로고
    • Role of inflammatory cells in fibroblast activation
    • COI: 1:CAS:528:DC%2BC2MXhvVyku7bI, PID: 26593723
    • Hartupee J, Mann DL (2016) Role of inflammatory cells in fibroblast activation. J Mol Cell Cardiol 93:143–148
    • (2016) J Mol Cell Cardiol , vol.93 , pp. 143-148
    • Hartupee, J.1    Mann, D.L.2
  • 28
    • 84937828512 scopus 로고    scopus 로고
    • Myofibroblasts
    • COI: 1:CAS:528:DC%2BC2MXht1SqtrrO, PID: 26192991
    • Hinz B (2016) Myofibroblasts. Exp Eye Res 142:56–70
    • (2016) Exp Eye Res , vol.142 , pp. 56-70
    • Hinz, B.1
  • 29
    • 84983759394 scopus 로고    scopus 로고
    • Role of T-cells in myocardial infarction
    • PID: 26646702
    • Hofmann U, Frantz S (2016) Role of T-cells in myocardial infarction. Eur Heart J 37:873–879
    • (2016) Eur Heart J , vol.37 , pp. 873-879
    • Hofmann, U.1    Frantz, S.2
  • 31
    • 84959544981 scopus 로고    scopus 로고
    • Myeloid-epithelial-reproductive receptor tyrosine kinase and milk fat globule epidermal growth factor 8 coordinately improve remodeling after myocardial infarction via local delivery of vascular endothelial growth factor
    • COI: 1:CAS:528:DC%2BC28XjslClt7o%3D, PID: 26819373
    • Howangyin KY, Zlatanova I, Pinto C, Ngkelo A, Cochain C, Rouanet M, Vilar J, Lemitre M, Stockmann C, Fleischmann BK, Mallat Z, Silvestre JS (2016) Myeloid-epithelial-reproductive receptor tyrosine kinase and milk fat globule epidermal growth factor 8 coordinately improve remodeling after myocardial infarction via local delivery of vascular endothelial growth factor. Circulation 133:826–839
    • (2016) Circulation , vol.133 , pp. 826-839
    • Howangyin, K.Y.1    Zlatanova, I.2    Pinto, C.3    Ngkelo, A.4    Cochain, C.5    Rouanet, M.6    Vilar, J.7    Lemitre, M.8    Stockmann, C.9    Fleischmann, B.K.10    Mallat, Z.11    Silvestre, J.S.12
  • 32
    • 34247866368 scopus 로고    scopus 로고
    • Thy-1 expression by cardiac fibroblasts: lack of association with myofibroblast contractile markers
    • COI: 1:CAS:528:DC%2BD2sXkvFKjt7s%3D, PID: 17395197
    • Hudon-David F, Bouzeghrane F, Couture P, Thibault G (2007) Thy-1 expression by cardiac fibroblasts: lack of association with myofibroblast contractile markers. J Mol Cell Cardiol 42:991–1000
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 991-1000
    • Hudon-David, F.1    Bouzeghrane, F.2    Couture, P.3    Thibault, G.4
  • 33
    • 84940121693 scopus 로고    scopus 로고
    • Cardiac nonmyocytes in the hub of cardiac hypertrophy
    • COI: 1:CAS:528:DC%2BC2MXhtVWrtrrJ, PID: 26089366
    • Kamo T, Akazawa H, Komuro I (2015) Cardiac nonmyocytes in the hub of cardiac hypertrophy. Circ Res 117:89–98
    • (2015) Circ Res , vol.117 , pp. 89-98
    • Kamo, T.1    Akazawa, H.2    Komuro, I.3
  • 36
    • 84887004755 scopus 로고    scopus 로고
    • Lack of specificity of fibroblast-specific protein 1 in cardiac remodeling and fibrosis
    • COI: 1:CAS:528:DC%2BC3sXhvFKhtbbO, PID: 23997102
    • Kong P, Christia P, Saxena A, Su Y, Frangogiannis NG (2013) Lack of specificity of fibroblast-specific protein 1 in cardiac remodeling and fibrosis. Am J Physiol Heart Circ Physiol 305:H1363–H1372
    • (2013) Am J Physiol Heart Circ Physiol , vol.305 , pp. H1363-H1372
    • Kong, P.1    Christia, P.2    Saxena, A.3    Su, Y.4    Frangogiannis, N.G.5
  • 37
    • 77957729712 scopus 로고    scopus 로고
    • The origin of fibroblasts and mechanism of cardiac fibrosis
    • COI: 1:CAS:528:DC%2BC3cXhtFGqsLzF, PID: 20635395
    • Krenning G, Zeisberg EM, Kalluri R (2010) The origin of fibroblasts and mechanism of cardiac fibrosis. J Cell Physiol 225:631–637
    • (2010) J Cell Physiol , vol.225 , pp. 631-637
    • Krenning, G.1    Zeisberg, E.M.2    Kalluri, R.3
  • 38
    • 0020633323 scopus 로고
    • Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo
    • COI: 1:CAS:528:DyaL3sXksFSqtLw%3D, PID: 6190091
    • Lane EB, Hogan BL, Kurkinen M, Garrels JI (1983) Co-expression of vimentin and cytokeratins in parietal endoderm cells of early mouse embryo. Nature 303:701–704
    • (1983) Nature , vol.303 , pp. 701-704
    • Lane, E.B.1    Hogan, B.L.2    Kurkinen, M.3    Garrels, J.I.4
  • 39
    • 84930741570 scopus 로고    scopus 로고
    • Getting to the heart of the matter new insights into cardiac fibrosis
    • COI: 1:CAS:528:DC%2BC2MXltlCktr4%3D, PID: 25814687
    • Leask A (2015) Getting to the heart of the matter new insights into cardiac fibrosis. Circ Res 116:1269–1276
    • (2015) Circ Res , vol.116 , pp. 1269-1276
    • Leask, A.1
  • 40
    • 84918511539 scopus 로고    scopus 로고
    • Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling
    • COI: 1:CAS:528:DC%2BC2cXitVyltLbK, PID: 25278099
    • Li L, Chen Y, Doan J, Murray J, Molkentin JD, Liu Q (2014) Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling. Circulation 130:2162–2172
    • (2014) Circulation , vol.130 , pp. 2162-2172
    • Li, L.1    Chen, Y.2    Doan, J.3    Murray, J.4    Molkentin, J.D.5    Liu, Q.6
  • 41
    • 84959261741 scopus 로고    scopus 로고
    • Leukocytes link local and systemic inflammation in ischemic cardiovascular disease: an expanded “cardiovascular continuum
    • Libby P, Nahrendorf M, Swirski FK (2015) Leukocytes link local and systemic inflammation in ischemic cardiovascular disease: an expanded “cardiovascular continuum”. J Am Coll Cardiol 67:1091–1103
    • (2015) J Am Coll Cardiol , vol.67 , pp. 1091-1103
    • Libby, P.1    Nahrendorf, M.2    Swirski, F.K.3
  • 42
    • 1942518857 scopus 로고    scopus 로고
    • cAMP-elevating agents and adenylyl cyclase overexpression promote an antifibrotic phenotype in pulmonary fibroblasts
    • COI: 1:CAS:528:DC%2BD2cXkt1emt7c%3D, PID: 15075208
    • Liu X, Ostrom RS, Insel PA (2004) cAMP-elevating agents and adenylyl cyclase overexpression promote an antifibrotic phenotype in pulmonary fibroblasts. Am J Physiol Cell Physiol 286:C1089–C1099
    • (2004) Am J Physiol Cell Physiol , vol.286 , pp. C1089-C1099
    • Liu, X.1    Ostrom, R.S.2    Insel, P.A.3
  • 43
    • 84871076444 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization in tissue repair and remodelling
    • COI: 1:CAS:528:DC%2BC38XhvVClt7nK, PID: 23096265
    • Mantovani A, Biswas SK, Galdiero MR, Sica A, Locati M (2013) Macrophage plasticity and polarization in tissue repair and remodelling. J Pathol 229:176–185
    • (2013) J Pathol , vol.229 , pp. 176-185
    • Mantovani, A.1    Biswas, S.K.2    Galdiero, M.R.3    Sica, A.4    Locati, M.5
  • 46
    • 21044458339 scopus 로고    scopus 로고
    • Expression of discoidin domain receptor 2 (DDR2) in the developing heart
    • COI: 1:CAS:528:DC%2BD2MXktVOqu7w%3D, PID: 16060979
    • Morales MO, Price RL, Goldsmith EC (2005) Expression of discoidin domain receptor 2 (DDR2) in the developing heart. Microsc Microanal 11:260–267
    • (2005) Microsc Microanal , vol.11 , pp. 260-267
    • Morales, M.O.1    Price, R.L.2    Goldsmith, E.C.3
  • 49
    • 7044274497 scopus 로고    scopus 로고
    • Thy-1 distinguishes human corneal fibroblasts and myofibroblasts from keratocytes
    • COI: 1:CAS:528:DC%2BD2cXovVKksrk%3D, PID: 15500828
    • Pei Y, Sherry DM, McDermott AM (2004) Thy-1 distinguishes human corneal fibroblasts and myofibroblasts from keratocytes. Exp Eye Res 79:705–712
    • (2004) Exp Eye Res , vol.79 , pp. 705-712
    • Pei, Y.1    Sherry, D.M.2    McDermott, A.M.3
  • 50
    • 84961231312 scopus 로고    scopus 로고
    • Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction
    • COI: 1:CAS:528:DC%2BC28XksVKltLY%3D, PID: 26926804
    • Piras BA, Tian Y, Xu Y, Thomas NA, O’Connor DM, French BA (2016) Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction. Gene Ther 23:469–478
    • (2016) Gene Ther , vol.23 , pp. 469-478
    • Piras, B.A.1    Tian, Y.2    Xu, Y.3    Thomas, N.A.4    O’Connor, D.M.5    French, B.A.6
  • 53
    • 79957624520 scopus 로고    scopus 로고
    • Fibrocytes: emerging effector cells in chronic inflammation
    • Reilkoff RA, Bucala R, Herzog EL (2011) Fibrocytes: emerging effector cells in chronic inflammation. Nat Rev Immunol 6:427–435
    • (2011) Nat Rev Immunol , vol.6 , pp. 427-435
    • Reilkoff, R.A.1    Bucala, R.2    Herzog, E.L.3
  • 54
    • 84925060829 scopus 로고    scopus 로고
    • Fibrosis—a common pathway to organ injury and failure
    • COI: 1:CAS:528:DC%2BC2MXlsVaku7o%3D, PID: 25785971
    • Rockey DC, Bell PD, Hill JA (2015) Fibrosis—a common pathway to organ injury and failure. New Eng J Med 372:1138–1149
    • (2015) New Eng J Med , vol.372 , pp. 1138-1149
    • Rockey, D.C.1    Bell, P.D.2    Hill, J.A.3
  • 55
  • 58
    • 0022881517 scopus 로고
    • A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation
    • COI: 1:CAS:528:DyaL2sXhtlKmu7s%3D, PID: 3539945
    • Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G (1986) A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol 103:2787–2796
    • (1986) J Cell Biol , vol.103 , pp. 2787-2796
    • Skalli, O.1    Ropraz, P.2    Trzeciak, A.3    Benzonana, G.4    Gillessen, D.5    Gabbiani, G.6
  • 59
    • 79958799319 scopus 로고    scopus 로고
    • Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling
    • COI: 1:CAS:528:DC%2BC3MXntF2htrc%3D, PID: 21512159
    • Smith CL, Baek ST, Sung CY, Tallquist MD (2011) Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling. Circ Res 108:e15–e26
    • (2011) Circ Res , vol.108 , pp. e15-e26
    • Smith, C.L.1    Baek, S.T.2    Sung, C.Y.3    Tallquist, M.D.4
  • 61
    • 84983738643 scopus 로고    scopus 로고
    • αSMA is an inconsistent marker of fibroblasts responsible for force dependent TGFβ activation or collagen production across multiple models of organ fibrosis
    • PID: 26944089
    • Sun KH, Chang Y, Reed NI, Sheppard D (2016) αSMA is an inconsistent marker of fibroblasts responsible for force dependent TGFβ activation or collagen production across multiple models of organ fibrosis. Am J Physiol Lung Cell Mol Physiol 310:L824–L836
    • (2016) Am J Physiol Lung Cell Mol Physiol , vol.310 , pp. L824-L836
    • Sun, K.H.1    Chang, Y.2    Reed, N.I.3    Sheppard, D.4
  • 64
    • 84878225291 scopus 로고    scopus 로고
    • A TRP to cardiac fibroblast differentiation
    • COI: 1:CAS:528:DC%2BC2cXjvFOrsrg%3D, PID: 23511028
    • Thodeti CK, Paruchuri S, Meszaros JG (2013) A TRP to cardiac fibroblast differentiation. Channels 7:211–214
    • (2013) Channels , vol.7 , pp. 211-214
    • Thodeti, C.K.1    Paruchuri, S.2    Meszaros, J.G.3
  • 68
    • 84903648153 scopus 로고    scopus 로고
    • Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription
    • COI: 1:CAS:528:DC%2BC2cXht1ygsb3I, PID: 24740541
    • Tsou PS, Haak AJ, Khanna D, Neubig RR (2014) Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription. Am J Physiol Cell Physiol 307:C2–C13
    • (2014) Am J Physiol Cell Physiol , vol.307 , pp. C2-C13
    • Tsou, P.S.1    Haak, A.J.2    Khanna, D.3    Neubig, R.R.4
  • 69
    • 84951129164 scopus 로고    scopus 로고
    • Inflammatory and fibrotic responses of cardiac fibroblasts to myocardial damage associated molecular patterns (DAMPs)
    • COI: 1:CAS:528:DC%2BC28XjtFChtw%3D%3D, PID: 26542796
    • Turner NA (2016) Inflammatory and fibrotic responses of cardiac fibroblasts to myocardial damage associated molecular patterns (DAMPs). J Mol Cell Cardiol 94:189–200
    • (2016) J Mol Cell Cardiol , vol.94 , pp. 189-200
    • Turner, N.A.1
  • 70
    • 34247849521 scopus 로고    scopus 로고
    • Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice
    • PID: 17322368
    • van Amerongen MJ, Harmsen MC, van Rooijen N, Petersen AH, van Luyn MJ (2007) Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J Pathol 170:818–829
    • (2007) Am J Pathol , vol.170 , pp. 818-829
    • van Amerongen, M.J.1    Harmsen, M.C.2    van Rooijen, N.3    Petersen, A.H.4    van Luyn, M.J.5
  • 72
    • 84885710467 scopus 로고    scopus 로고
    • Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing
    • COI: 1:CAS:528:DC%2BC3sXhslejsbrP, PID: 24082095
    • Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM (2013) Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing. Proc Natl Acad Sci USA 110:16850–16855
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 16850-16855
    • Velasquez, L.S.1    Sutherland, L.B.2    Liu, Z.3    Grinnell, F.4    Kamm, K.E.5    Schneider, J.W.6    Olson, E.N.7    Small, E.M.8
  • 73
    • 84966697317 scopus 로고    scopus 로고
    • Endothelium-derived 5-methoxytryptophan is a circulating anti-inflammatory molecule that blocks systemic inflammation
    • COI: 1:CAS:528:DC%2BC28XhtFaisLfF, PID: 27151398
    • Wang YF, Hsu YJ, Wu HF, Lee GL, Yang YS, Wu JY, Yet SF, Wu KK, Cheng-Chin Kuo CC (2016) Endothelium-derived 5-methoxytryptophan is a circulating anti-inflammatory molecule that blocks systemic inflammation. Circ Res 119:222–236
    • (2016) Circ Res , vol.119 , pp. 222-236
    • Wang, Y.F.1    Hsu, Y.J.2    Wu, H.F.3    Lee, G.L.4    Yang, Y.S.5    Wu, J.Y.6    Yet, S.F.7    Wu, K.K.8    Cheng-Chin Kuo, C.C.9
  • 74
    • 84930086048 scopus 로고    scopus 로고
    • Pericytes, mesenchymal stem cells and their contributions to tissue repair
    • COI: 1:CAS:528:DC%2BC2MXlvVSlsLo%3D, PID: 25827580
    • Wong SP, Rowley JE, Redpath AN, Tilman JD, Fellous TG, Johnson JR (2015) Pericytes, mesenchymal stem cells and their contributions to tissue repair. Pharmacol Ther 151:107–120
    • (2015) Pharmacol Ther , vol.151 , pp. 107-120
    • Wong, S.P.1    Rowley, J.E.2    Redpath, A.N.3    Tilman, J.D.4    Fellous, T.G.5    Johnson, J.R.6
  • 78
    • 84919733534 scopus 로고    scopus 로고
    • Epigenetic modifications in fibrotic diseases: implications for pathogenesis and pharmacological targets
    • PID: 25362107
    • Yao HW, Li J (2015) Epigenetic modifications in fibrotic diseases: implications for pathogenesis and pharmacological targets. J Pharmacol Exp Ther 352:2–13
    • (2015) J Pharmacol Exp Ther , vol.352 , pp. 2-13
    • Yao, H.W.1    Li, J.2
  • 79
    • 0037309642 scopus 로고    scopus 로고
    • DNase I-hypersensitive sites enhance alpha1(I) collagen gene expression in hepatic stellate cells
    • COI: 1:CAS:528:DC%2BD3sXhsFelsbw%3D, PID: 12540776
    • Yata Y, Scanga A, Gillan A, Yang L, Reif S, Breindl M, Brenner DA, Rippe RA (2003) DNase I-hypersensitive sites enhance alpha1(I) collagen gene expression in hepatic stellate cells. Hepatology 37:267–276
    • (2003) Hepatology , vol.37 , pp. 267-276
    • Yata, Y.1    Scanga, A.2    Gillan, A.3    Yang, L.4    Reif, S.5    Breindl, M.6    Brenner, D.A.7    Rippe, R.A.8
  • 82
    • 85001122938 scopus 로고    scopus 로고
    • Necrotic myocardial cells release damage-associated molecular patterns that provoke fibroblast activation in vitro and trigger myocardial inflammation and fibrosis in vivo
    • PID: 26037082
    • Zhang W, Lavine KJ, Epelman S, Evans SA, Weinheimer CJ, Barger PM, Mann DL (2015) Necrotic myocardial cells release damage-associated molecular patterns that provoke fibroblast activation in vitro and trigger myocardial inflammation and fibrosis in vivo. J Am Heart Assoc 4:e001993
    • (2015) J Am Heart Assoc , vol.4
    • Zhang, W.1    Lavine, K.J.2    Epelman, S.3    Evans, S.A.4    Weinheimer, C.J.5    Barger, P.M.6    Mann, D.L.7


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