The αvβ1 integrin plays a critical in vivo role in tissue fibrosis

Science Translational Medicine

Volumn 7, Issue 288, 2015, Pages

  Reed, Nilgun I ^a   Jo, Hyunil ^b   Chen, Chun ^a   Tsujino, Kazuyuki ^a   Arnold, Thomas D ^a   DeGrado, William F ^b   Sheppard, Dean ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAVBETA1 INTEGRIN; ALPHAVBETA1 INTEGRIN INHIBITOR; INTEGRIN; PROTEIN INHIBITOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; BLEOMYCIN; BROMINATED HYDROCARBON; CARBON TETRABROMIDE; INTEGRIN ALPHAVBETA1; TRANSFORMING GROWTH FACTOR BETA; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING; DRUG DESIGN; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; FIBROBLAST; LIVER FIBROSIS; LIVER PROTECTION; LUNG FIBROSIS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CHEMICAL AND DRUG INDUCED LIVER INJURY; CHEMICALLY INDUCED; DRUG EFFECTS; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; LUNG; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PULMONARY FIBROSIS; SIGNAL TRANSDUCTION;

ANIMALS; BLEOMYCIN; CELLS, CULTURED; CHEMICAL AND DRUG INDUCED LIVER INJURY; DRUG DESIGN; FIBROBLASTS; HYDROCARBONS, BROMINATED; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; LUNG; MICE; MICE, INBRED C57BL; MOLECULAR TARGETED THERAPY; PULMONARY FIBROSIS; RECEPTORS, VITRONECTIN; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84929815757     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa5094     Document Type: Article

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