Revealing new mouse epicardial cell markers through transcriptomics

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Bochmann, Lars ^a,b,c   Sarathchandra, Padmini ^b   Mori, Federica ^c   Lara Pezzi, Enrique ^a,d   Lazzaro, Domenico ^c   Rosenthal, Nadia ^a,b  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c IRBM   (Italy)

^d CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALDEHYDE DEHYDROGENASE; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; AMYLOID PROTEIN; ANNEXIN; BASONUCLIN; CHITINASE; CLAUDIN; COMPLEMENT COMPONENT C2; COMPLEMENT COMPONENT C3; CYTOCHROME P450; CYTOCHROME REDUCTASE; CYTOKERATIN 19; CYTOKERATIN 8; CYTOKINE; DERMOKINE; DNA; GLYCOPROTEIN; GLYCOPROTEIN M6A; GUANINE NUCLEOTIDE BINDING PROTEIN; MUCIN; MYELIN PROTEIN; PROLINE RICH PROTEIN; SCLEROPROTEIN; SOMATOMEDIN BINDING PROTEIN 6; SOMATOMEDIN C; T BOX TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; UROPLAKIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; EPICARDIUM; FROZEN SECTION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART DEVELOPMENT; HEART INFARCTION; HEART MUSCLE CELL; ISOLATED HEART; LASER MICROSCOPY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; TISSUE REPAIR; TRANSCRIPTOMICS; TRANSGENICS; UNINDEXED SEQUENCE; WILD TYPE;

MURINAE; MUS;

EID: 77955323254     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011429     Document Type: Article

References (35)

1. Zhou B, Ma Q, Rajagopal S, Wu SM, Domian I, et al. (2008) Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature 454: 109-113.
2. Cai CL, Martin JC, Sun Y, Cui L, Wang L, et al. (2008) A myocardial lineage derives from Tbx18 epicardial cells. Nature 454: 104-108.
3. Reese DE, Mikawa T, Bader DM (2002) Development of the coronary vessel system. Circ Res 91: 761-768.
4. van Wijk B, van den Berg G, Abu-Issa R, Barnett P, van der Velden S, et al. (2009) Epicardium and myocardium separate from a common precursor pool by crosstalk between bone morphogenetic protein- and fibroblast growth factorsignaling pathways. Circ Res 105: 431-441.
5. Winter EM, Gittenberger-de Groot AC (2007) Epicardium-derived cells in cardiogenesis and cardiac regeneration. Cell Mol Life Sci 64: 692-703.
6. Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, et al. (2007) Thymosin beta-4 is essential for coronary vessel development and promotes neovascularization via adult epicardium. Ann N Y Acad Sci 1112: 171-188.
7. Christoffels VM, Grieskamp T, Norden J, Mommersteeg MT, Rudat C, et al. (2009) Tbx18 and the fate of epicardial progenitors. Nature 458: E8-9; discussion E9-10.
8. Lepilina A, Coon AN, Kikuchi K, Holdway JE, Roberts RW, et al. (2006) A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration. Cell 127: 607-619.
9. Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, et al. (2007) Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature 445: 177-182.
10. Bock-Marquette I, Shrivastava S, Pipes GC, Thatcher JE, Blystone A, et al. (2009) Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J Mol Cell Cardiol 46: 728-738.
11. Riley PR, Smart N (2009) Thymosin beta4 induces epicardium-derived neovascularization in the adult heart. Biochem Soc Trans 37: 1218-1220.
12. Limana F, Zacheo A, Mocini D, Mangoni A, Borsellino G, et al. (2007) Identification of myocardial and vascular precursor cells in human and mouse epicardium. Circ Res 101: 1255-1265.
13. Winter EM, Grauss RW, Hogers B, van Tuyn J, van der Geest R, et al. (2007) Preservation of left ventricular function and attenuation of remodeling after transplantation of human epicardium-derived cells into the infarcted mouse heart. Circulation 116: 917-927.
14. Winter EM, van Oorschot AA, Hogers B, van der Graaf LM, Doevendans PA, et al. (2009) A new direction for cardiac regeneration therapy: application of synergistically acting epicardium-derived cells and cardiomyocyte progenitor cells. Circ Heart Fail 2: 643-653.
15. Hatcher CJ, Diman NY, Kim MS, Pennisi D, Song Y, et al. (2004) A role for Tbx5 in proepicardial cell migration during cardiogenesis. Physiol Genomics 18: 129-140.
16. Kang J, Gu Y, Li P, Johnson BL, Sucov HM, et al. (2008) PDGF-A as an epicardial mitogen during heart development. Dev Dyn 237: 692-701.
17. Lu J, Richardson JA, Olson EN (1998) Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs. Mech Dev 73: 23-32.
18. Thorrez L, Van Deun K, Tranchevent LC, Van Lommel L, Engelen K, et al. (2008) Using ribosomal protein genes as reference: a tale of caution. PLoS One 3: e1854.
19. Moss JB, Xavier-Neto J, Shapiro MD, Nayeem SM, McCaffery P, et al. (1998) Dynamic patterns of retinoic acid synthesis and response in the developing mammalian heart. Dev Biol 199: 55-71.
20. Niederreither K, Fraulob V, Garnier JM, Chambon P, Dolle P (2002) Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech Dev 110: 165-171.
21. Xavier-Neto J, Shapiro MD, Houghton L, Rosenthal N (2000) Sequential programs of retinoic acid synthesis in the myocardial and epicardial layers of the developing avian heart. Dev Biol 219: 129-141.
22. Lee JM, Dedhar S, Kalluri R, Thompson EW (2006) The epithelialmesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 172: 973-981.
23. Zhang T, Li X, Yu W, Yan Z, Zou H, et al. (2009) Overexpression of thymosin beta-10 inhibits VEGF mRNA expression, autocrine VEGF protein production, and tube formation in hypoxia-induced monkey choroid-retinal endothelial cells. Ophthalmic Res 41: 36-43.
24. Rosati B, Grau F, McKinnon D (2006) Regional variation in mRNA transcript abundance within the ventricular wall. J Mol Cell Cardiol 40: 295-302.
25. Basset-Seguin N, Yancey KB (1992) [Cleavage fragments of C3 and of dermoepidermal junction of normal human skin]. Ann Dermatol Venereol 119: 629-634.
26. Andoh A, Fujiyama Y, Hata K, Sumiyoshi K, Bamba T (1996) Regulation of complement C3 synthesis by interleukin-1 and transforming growth factor-beta in rat non-transformed intestinal epithelial cell line, IEC-6. J Gastroenterol 31: 633-638.
27. Matsui T, Hayashi-Kisumi F, Kinoshita Y, Katahira S, Morita K, et al. (2004) Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1. Genomics 84: 384-397.
28. Brass EP, Peters MA, Hinchcliff KW, He YD, Ulrich RG (2009) Temporal pattern of skeletal muscle gene expression following endurance exercise in Alaskan sled dogs. J Appl Physiol 107: 605-612.
29. Zhang X, Tseng H (2007) Basonuclin-null mutation impairs homeostasis and wound repair in mouse corneal epithelium. PLoS ONE 2: e1087.
30. Vanhoutteghem A, Djian P (2004) Basonuclin 2: an extremely conserved homolog of the zinc finger protein basonuclin. Proc Natl Acad Sci U S A 101: 3468-3473.
31. Alves CC, Carneiro F, Hoefler H, Becker KF (2009) Role of the epithelialmesenchymal transition regulator Slug in primary human cancers. Front Biosci 14: 3035-3050.
32. Santini MP, Tsao L, Monassier L, Theodoropoulos C, Carter J, et al. (2007) Enhancing Repair of the Mammalian Heart. Circ Res 100: 1732-1740.
33. Limana F, Bertolami C, Mangoni A, Di Carlo A, Avitabile D, et al. Myocardial infarction induces embryonic reprogramming of epicardial c-kit(+) cells: role of the pericardial fluid. J Mol Cell Cardiol 48: 609-618.
34. Tarnavski O, McMullen JR, Schinke M, Nie Q, Kong S, et al. (2004) Mouse cardiac surgery: comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies. Physiol Genomics 16: 349-360.
35. Zheng Q, Wang XJ (2008) GOEAST: a web-based software toolkit for Gene Ontology enrichment analysis. Nucleic Acids Res 36: W358-363.