-
1
-
-
33846434062
-
Shaping of monocyte and macrophage function by adenosine receptors
-
Haskó, G., P. Pacher, E. A. Deitch, and E. S. Vizi. 2007. Shaping of monocyte and macrophage function by adenosine receptors. Pharmacol. Ther. 113: 264-275.
-
(2007)
Pharmacol. Ther.
, vol.113
, pp. 264-275
-
-
Haskó, G.1
Pacher, P.2
Deitch, E.A.3
Vizi, E.S.4
-
2
-
-
0035209620
-
International Union of Pharmacology
-
Fredholm, B. B., A. P. IJzerman, K. A. Jacobson, K. N. Klotz, and J. Linden. 2001. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol. Rev. 53: 527-552.
-
(2001)
XXV. Nomenclature and Classification of Adenosine Receptors. Pharmacol. Rev.
, vol.53
, pp. 527-552
-
-
Fredholm, B.B.1
Ijzerman, A.P.2
Jacobson, K.A.3
Klotz, K.N.4
Linden, J.5
-
4
-
-
84875700546
-
Adenosine receptors as drug targets-what are the challenges? Nat
-
Chen, J. F., H. K. Eltzschig, and B. B. Fredholm. 2013. Adenosine receptors as drug targets-what are the challenges? Nat. Rev. Drug Discov. 12: 265-286.
-
(2013)
Rev. Drug Discov.
, vol.12
, pp. 265-286
-
-
Chen, J.F.1
Eltzschig, H.K.2
Fredholm, B.B.3
-
5
-
-
84883698279
-
Regulation of inflammation by adenosine
-
Haskó, G., and B. Cronstein. 2013. Regulation of inflammation by adenosine. Front. Immunol. 4: 85.
-
(2013)
Front. Immunol.
, vol.4
, pp. 85
-
-
Haskó, G.1
Cronstein, B.2
-
6
-
-
84876800337
-
Macrophage biology in development, homeostasis and disease
-
Wynn, T. A., A. Chawla, and J. W. Pollard. 2013. Macrophage biology in development, homeostasis and disease. Nature 496: 445-455.
-
(2013)
Nature
, vol.496
, pp. 445-455
-
-
Wynn, T.A.1
Chawla, A.2
Pollard, J.W.3
-
7
-
-
27744593781
-
Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: Role of NF-kappaB in A(2A) adenosine receptor induction
-
Murphree, L. J., G. W. Sullivan, M. A. Marshall, and J. Linden. 2005. Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction. Biochem. J. 391: 575-580.
-
(2005)
Biochem. J.
, vol.391
, pp. 575-580
-
-
Murphree, L.J.1
Sullivan, G.W.2
Marshall, M.A.3
Linden, J.4
-
8
-
-
77949363933
-
The role of adenosine receptors in regulating production of tumour necrosis factor-A and chemokines by human lung macrophages
-
Buenestado, A., S. Grassin Delyle, I. Arnould, F. Besnard, E. Naline, S. Blouquit-Laye, A. Chapelier, J. F. Bellamy, and P. Devillier. 2010. The role of adenosine receptors in regulating production of tumour necrosis factor-A and chemokines by human lung macrophages. Br. J. Pharmacol. 159: 1304-1311.
-
(2010)
Br. J. Pharmacol.
, vol.159
, pp. 1304-1311
-
-
Buenestado, A.1
Grassin Delyle, S.2
Arnould, I.3
Besnard, F.4
Naline, E.5
Blouquit-Laye, S.6
Chapelier, A.7
Bellamy, J.F.8
Devillier, P.9
-
9
-
-
0030588630
-
Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice
-
Haskó, G., C. Szabó, Z. H. Németh, V. Kvetan, S. M. Pastores, and E. S. Vizi. 1996. Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J. Immunol. 157: 4634-4640.
-
(1996)
J. Immunol.
, vol.157
, pp. 4634-4640
-
-
Haskó, G.1
Szabó, C.2
Németh, Z.H.3
Kvetan, V.4
Pastores, S.M.5
Vizi, E.S.6
-
10
-
-
84863776052
-
The effect of A(2A) adenosine receptor activation on C-C chemokine receptor 7 expression in human THP1 macrophages during inflammation
-
Williams, A. J., and B. N. Cronstein. 2012. The effect of A(2A) adenosine receptor activation on C-C chemokine receptor 7 expression in human THP1 macrophages during inflammation. Inflammation 35: 614-622.
-
(2012)
Inflammation
, vol.35
, pp. 614-622
-
-
Williams, A.J.1
Cronstein, B.N.2
-
11
-
-
79953180610
-
Inflammation: A role for NR4A orphan nuclear receptors? Biochem
-
McMorrow, J. P., and E. P. Murphy. 2011. Inflammation: a role for NR4A orphan nuclear receptors? Biochem. Soc. Trans. 39: 688-693.
-
(2011)
Soc. Trans.
, vol.39
, pp. 688-693
-
-
McMorrow, J.P.1
Murphy, E.P.2
-
12
-
-
70349443394
-
Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis
-
Aherne, C. M., J. McMorrow, D. Kane, O. FitzGerald, K. S. Mix, and E. P. Murphy. 2009. Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis. Mol. Immunol. 46: 3345-3357.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 3345-3357
-
-
Aherne, C.M.1
McMorrow, J.2
Kane, D.3
FitzGerald, O.4
Mix, K.S.5
Murphy, E.P.6
-
13
-
-
63049083734
-
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
-
Saijo, K., B.Winner, C. T. Carson, J. G. Collier, L. Boyer, M. G. Rosenfeld, F. H. Gage, and C. K. Glass. 2009. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 137: 47-59.
-
(2009)
Cell
, vol.137
, pp. 47-59
-
-
Saijo, K.1
Winner, B.2
Carson, C.T.3
Collier, J.G.4
Boyer, L.5
Rosenfeld, M.G.6
Gage, F.H.7
Glass, C.K.8
-
14
-
-
77955157737
-
NR4A orphan nuclear receptors: Transcriptional regulators of gene expression in metabolism and vascular biology
-
Zhao, Y., and D. Bruemmer. 2010. NR4A orphan nuclear receptors: transcriptional regulators of gene expression in metabolism and vascular biology. Arterioscler. Thromb. Vasc. Biol. 30: 1535-1541.
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 1535-1541
-
-
Zhao, Y.1
Bruemmer, D.2
-
15
-
-
80051959957
-
The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6Cmonocytes
-
Hanna, R. N., L. M. Carlin, H. G. Hubbeling, D. Nackiewicz, A. M. Green, J. A. Punt, F. Geissmann, and C. C. Hedrick. 2011. The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6Cmonocytes. Nat. Immunol. 12: 778-785.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 778-785
-
-
Hanna, R.N.1
Carlin, L.M.2
Hubbeling, H.G.3
Nackiewicz, D.4
Green, A.M.5
Punt, J.A.6
Geissmann, F.7
Hedrick, C.C.8
-
16
-
-
84856707159
-
NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis
-
Hanna, R. N., I. Shaked, H. G. Hubbeling, J. A. Punt, R. Wu, E. Herrley, C. Zaugg, H. Pei, F. Geissmann, K. Ley, and C. C. Hedrick. 2012. NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis. Circ. Res. 110: 416-427.
-
(2012)
Circ. Res.
, vol.110
, pp. 416-427
-
-
Hanna, R.N.1
Shaked, I.2
Hubbeling, H.G.3
Punt, J.A.4
Wu, R.5
Herrley, E.6
Zaugg, C.7
Pei, H.8
Geissmann, F.9
Ley, K.10
Hedrick, C.C.11
-
17
-
-
85027932757
-
Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis
-
Sekiya, T., I. Kashiwagi, R. Yoshida, T. Fukaya, R. Morita, A. Kimura, H. Ichinose, D. Metzger, P. Chambon, and A. Yoshimura. 2013. Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis. Nat. Immunol. 14: 230-237.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 230-237
-
-
Sekiya, T.1
Kashiwagi, I.2
Yoshida, R.3
Fukaya, T.4
Morita, R.5
Kimura, A.6
Ichinose, H.7
Metzger, D.8
Chambon, P.9
Yoshimura, A.10
-
18
-
-
79953769170
-
The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
-
Sekiya, T., I. Kashiwagi, N. Inoue, R. Morita, S. Hori, H. Waldmann, A. Y. Rudensky, H. Ichinose, D. Metzger, P. Chambon, and A. Yoshimura. 2011. The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells. Nat. Commun. 2: 269.
-
(2011)
Nat. Commun.
, vol.2
, pp. 269
-
-
Sekiya, T.1
Kashiwagi, I.2
Inoue, N.3
Morita, R.4
Hori, S.5
Waldmann, H.6
Rudensky, A.Y.7
Ichinose, H.8
Metzger, D.9
Chambon, P.10
Yoshimura, A.11
-
19
-
-
21244460254
-
Modulation of orphan nuclear receptor NURR1 expression by methotrexate in human inflammatory joint disease involves adenosine A2A receptor-mediated responses
-
Ralph, J. A., A. N. McEvoy, D. Kane, B. Bresnihan, O. FitzGerald, and E. P. Murphy. 2005. Modulation of orphan nuclear receptor NURR1 expression by methotrexate in human inflammatory joint disease involves adenosine A2A receptor-mediated responses. J. Immunol. 175: 555-565.
-
(2005)
J. Immunol.
, vol.175
, pp. 555-565
-
-
Ralph, J.A.1
McEvoy, A.N.2
Kane, D.3
Bresnihan, B.4
FitzGerald, O.5
Murphy, E.P.6
-
20
-
-
79952642792
-
Selective regulation of nuclear orphan receptors 4A by adenosine receptor subtypes in human mast cells
-
Zhang, L., C. Paine, and R. Dip. 2010. Selective regulation of nuclear orphan receptors 4A by adenosine receptor subtypes in human mast cells. J. Cell Commun. Signal. 4: 173-183.
-
(2010)
J. Cell Commun. Signal.
, vol.4
, pp. 173-183
-
-
Zhang, L.1
Paine, C.2
Dip, R.3
-
21
-
-
84884568692
-
Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity
-
McMorrow, J. P., D. Crean, M. Gogarty, A. Smyth, M. Connolly, E. Cummins, D. Veale, U. Fearon, P. P. Tak, O. Fitzgerald, and E. P. Murphy. 2013. Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity. Am. J. Pathol. 183: 1243-1257.
-
(2013)
Am. J. Pathol.
, vol.183
, pp. 1243-1257
-
-
McMorrow, J.P.1
Crean, D.2
Gogarty, M.3
Smyth, A.4
Connolly, M.5
Cummins, E.6
Veale, D.7
Fearon, U.8
Tak, P.P.9
FitzGerald, O.10
Murphy, E.P.11
-
22
-
-
33845646748
-
Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury
-
Leonard, M. O., N. E. Kieran, K. Howell, M. J. Burne, R. Varadarajan, S. Dhakshinamoorthy, A. G. Porter, C. O'Farrelly, H. Rabb, and C. T. Taylor. 2006. Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury. FASEB J. 20: 2624-2626.
-
(2006)
FASEB J.
, vol.20
, pp. 2624-2626
-
-
Leonard, M.O.1
Kieran, N.E.2
Howell, K.3
Burne, M.J.4
Varadarajan, R.5
Dhakshinamoorthy, S.6
Porter, A.G.7
O'farrelly, C.8
Rabb, H.9
Taylor, C.T.10
-
23
-
-
84863165430
-
FOXO1 increases CCL20 to promote NF-kB-dependent lymphocyte chemotaxis
-
Miao, H., Y. Zhang, Z. Lu, L. Yu, and L. Gan. 2012. FOXO1 increases CCL20 to promote NF-kB-dependent lymphocyte chemotaxis. Mol. Endocrinol. 26: 423-437.
-
(2012)
Mol. Endocrinol.
, vol.26
, pp. 423-437
-
-
Miao, H.1
Zhang, Y.2
Lu, Z.3
Yu, L.4
Gan, L.5
-
24
-
-
84888781899
-
Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages
-
Koscsó , B., B. Csóka, E. Kókai, Z. H. Németh, P. Pacher, L. Virág, S. J. Leibovich, and G. Haskó. 2013. Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages. J. Leukoc. Biol. 94: 1309-1315.
-
(2013)
J. Leukoc. Biol.
, vol.94
, pp. 1309-1315
-
-
Koscsó, B.1
Csóka, B.2
Kókai, E.3
Németh, Z.H.4
Pacher, P.5
Virág, L.6
Leibovich, S.J.7
Haskó, G.8
-
25
-
-
84872940943
-
Adenosine A2A receptor and TNF-A regulate the circadian machinery of the human monocytic THP-1 cells
-
Perez-Aso, M., J. L. Feig, A. Mediero, and B. N. Cronstein. 2013. Adenosine A2A receptor and TNF-A regulate the circadian machinery of the human monocytic THP-1 cells. Inflammation 36: 152-162.
-
(2013)
Inflammation
, vol.36
, pp. 152-162
-
-
Perez-Aso, M.1
Feig, J.L.2
Mediero, A.3
Cronstein, B.N.4
-
26
-
-
84859430577
-
Cholesterol 27-hydroxylase but not apolipoprotein apoE contributes to A2A adenosine receptor stimulated reverse cholesterol transport
-
Bingham, T. C., S. Parathath, H. Tian, A. Reiss, E. Chan, E. A. Fisher, and B. N. Cronstein. 2012. Cholesterol 27-hydroxylase but not apolipoprotein apoE contributes to A2A adenosine receptor stimulated reverse cholesterol transport. Inflammation 35: 49-57.
-
(2012)
Inflammation
, vol.35
, pp. 49-57
-
-
Bingham, T.C.1
Parathath, S.2
Tian, H.3
Reiss, A.4
Chan, E.5
Fisher, E.A.6
Cronstein, B.N.7
-
27
-
-
77951025078
-
Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation
-
Barnholt, K. E., R. S. Kota, H. H. Aung, and J. C. Rutledge. 2009. Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation. J. Immunol. 183: 6767-6777.
-
(2009)
J. Immunol.
, vol.183
, pp. 6767-6777
-
-
Barnholt, K.E.1
Kota, R.S.2
Aung, H.H.3
Rutledge, J.C.4
-
28
-
-
73549104499
-
Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype
-
Grinberg, S., G. Hasko, D. Wu, and S. J. Leibovich. 2009. Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype. Am. J. Pathol. 175: 2439-2453.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 2439-2453
-
-
Grinberg, S.1
Hasko, G.2
Wu, D.3
Leibovich, S.J.4
-
29
-
-
63149154973
-
Tumor-associated macrophageinduced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction
-
Tjiu, J. W., J. S. Chen, C. T. Shun, S. J. Lin, Y. H. Liao, C. Y. Chu, T. F. Tsai, H. C. Chiu, Y. S. Dai, H. Inoue, et al. 2009. Tumor-associated macrophageinduced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction. J. Invest. Dermatol. 129: 1016-1025.
-
(2009)
J. Invest. Dermatol.
, vol.129
, pp. 1016-1025
-
-
Tjiu, J.W.1
Chen, J.S.2
Shun, C.T.3
Lin, S.J.4
Liao, Y.H.5
Chu, C.Y.6
Tsai, T.F.7
Chiu, H.C.8
Dai, Y.S.9
Inoue, H.10
-
30
-
-
33644770260
-
Adenosine receptors as therapeutic targets
-
Jacobson, K. A., and Z. G. Gao. 2006. Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov. 5: 247-264.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 247-264
-
-
Jacobson, K.A.1
Gao, Z.G.2
-
31
-
-
79952027612
-
Recent developments in adenosine receptor ligands and their potential as novel drugs
-
Müller, C. E., and K. A. Jacobson. 2011. Recent developments in adenosine receptor ligands and their potential as novel drugs. Biochim. Biophys. Acta 1808: 1290-1308.
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 1290-1308
-
-
Müller, C.E.1
Jacobson, K.A.2
-
32
-
-
79957587060
-
Cooperation of adenosine with macrophage Toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene
-
Ruiz-Garc?a, A., E. Monsalve, L. Novellasdemunt, A. Navarro-Sabaté, A. Manzano, S. Rivero, A. Castrillo, M. Casado, J. Laborda, R. Bartrons, and M. J. D?az-Guerra. 2011. Cooperation of adenosine with macrophage Toll-4 receptor agonists leads to increased glycolytic flux through the enhanced expression of PFKFB3 gene. J. Biol. Chem. 286: 19247-19258.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 19247-19258
-
-
Ruiz-Garća, A.1
Monsalve, E.2
Novellasdemunt, L.3
Navarro-Sabaté, A.4
Manzano, A.5
Rivero, S.6
Castrillo, A.7
Casado, M.8
Laborda, J.9
Bartrons, R.10
Daz-Guerra, M.J.11
-
33
-
-
77956650878
-
NR4A orphan nuclear receptors in cardiovascular biology
-
Zhao, Y., and D. Bruemmer. 2009. NR4A orphan nuclear receptors in cardiovascular biology. Drug Discov. Today Dis. Mech. 6: e43-e48.
-
(2009)
Drug Discov. Today Dis. Mech.
, vol.6
, pp. e43-e48
-
-
Zhao, Y.1
Bruemmer, D.2
-
34
-
-
84897556094
-
The M1 and M2 paradigm of macrophage activation: Time for reassessment
-
Martinez, F. O., and S. Gordon. 2014. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep. 6: 13.
-
(2014)
F1000Prime Rep.
, vol.6
, pp. 13
-
-
Martinez, F.O.1
Gordon, S.2
-
35
-
-
0031106065
-
Adenosine increases interleukin 6 release and decreases tumour necrosis factor release from rat adrenal zona glomerulosa cells, ovarian cells, anterior pituitary cells, and peritoneal macrophages
-
Ritchie, P. K., B. L. Spangelo, D. K. Krzymowski, T. B. Rossiter, E. Kurth, and A. M. Judd. 1997. Adenosine increases interleukin 6 release and decreases tumour necrosis factor release from rat adrenal zona glomerulosa cells, ovarian cells, anterior pituitary cells, and peritoneal macrophages. Cytokine 9: 187-198.
-
(1997)
Cytokine
, vol.9
, pp. 187-198
-
-
Ritchie, P.K.1
Spangelo, B.L.2
Krzymowski, D.K.3
Rossiter, T.B.4
Kurth, E.5
Judd, A.M.6
-
36
-
-
51049101334
-
Adenosine receptors: Therapeutic aspects for inflammatory and immune diseases
-
Haskó, G., J. Linden, B. Cronstein, and P. Pacher. 2008. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat. Rev. Drug Discov. 7: 759-770.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 759-770
-
-
Haskó, G.1
Linden, J.2
Cronstein, B.3
Pacher, P.4
-
37
-
-
84887013719
-
TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses
-
Cohen, H. B., K. T. Briggs, J. P. Marino, K. Ravid, S. C. Robson, and D. M. Mosser. 2013. TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses. Blood 122: 1935-1945.
-
(2013)
Blood
, vol.122
, pp. 1935-1945
-
-
Cohen, H.B.1
Briggs, K.T.2
Marino, J.P.3
Ravid, K.4
Robson, S.C.5
Mosser, D.M.6
-
38
-
-
38349014249
-
Wound healing is impaired in MyD88-deficient mice: A role for MyD88 in the regulation of wound healing by adenosine A2A receptors
-
Macedo, L., G. Pinhal-Enfield, V. Alshits, G. Elson, B. N. Cronstein, and S. J. Leibovich. 2007. Wound healing is impaired in MyD88-deficient mice: a role for MyD88 in the regulation of wound healing by adenosine A2A receptors. Am. J. Pathol. 171: 1774-1788.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 1774-1788
-
-
Macedo, L.1
Pinhal-Enfield, G.2
Alshits, V.3
Elson, G.4
Cronstein, B.N.5
Leibovich, S.J.6
-
39
-
-
0038603203
-
Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells
-
Panther, E., S. Corinti, M. Idzko, Y. Herouy, M. Napp, A. la Sala, G. Girolomoni, and J. Norgauer. 2003. Adenosine affects expression of membrane molecules, cytokine and chemokine release, and the T-cell stimulatory capacity of human dendritic cells. Blood 101: 3985-3990.
-
(2003)
Blood
, vol.101
, pp. 3985-3990
-
-
Panther, E.1
Corinti, S.2
Idzko, M.3
Herouy, Y.4
Napp, M.5
La Sala, A.6
Girolomoni, G.7
Norgauer, J.8
-
40
-
-
33749061994
-
Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses
-
Bonta, P. I., C. M. van Tiel, M. Vos, T. W. Pols, J. V. van Thienen, V. Ferreira, E. K. Arkenbout, J. Seppen, C. A. Spek, T. van der Poll, et al. 2006. Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses. Arterioscler. Thromb. Vasc. Biol. 26: 2288-2294.
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 2288-2294
-
-
Bonta, P.I.1
Van Tiel, C.M.2
Vos, M.3
Pols, T.W.4
Van Thienen, J.V.5
Ferreira, V.6
Arkenbout, E.K.7
Seppen, J.8
Spek, C.A.9
Poll Der T.Van10
-
41
-
-
84901056045
-
Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium
-
Hilgendorf, I., L. M. Gerhardt, T. C. Tan, C. Winter, T. A. Holderried, B. G. Chousterman, Y. Iwamoto, R. Liao, A. Zirlik, M. Scherer-Crosbie, et al. 2014. Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium. Circ. Res. 114: 1611-1622.
-
(2014)
Circ. Res.
, vol.114
, pp. 1611-1622
-
-
Hilgendorf, I.1
Gerhardt, L.M.2
Tan, T.C.3
Winter, C.4
Holderried, T.A.5
Chousterman, B.G.6
Iwamoto, Y.7
Liao, R.8
Zirlik, A.9
Scherer-Crosbie, M.10
-
42
-
-
79961042393
-
Adenosine negative feedback on A2A adenosine receptors mediates hyporesponsiveness in chronically septic mice
-
Belikoff, B., S. Hatfield, M. Sitkovsky, and D. G. Remick. 2011. Adenosine negative feedback on A2A adenosine receptors mediates hyporesponsiveness in chronically septic mice. Shock 35: 382-387.
-
(2011)
Shock
, vol.35
, pp. 382-387
-
-
Belikoff, B.1
Hatfield, S.2
Sitkovsky, M.3
Remick, D.G.4
-
43
-
-
0036087180
-
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin
-
Leibovich, S. J., J. F. Chen, G. Pinhal-Enfield, P. C. Belem, G. Elson, A. Rosania, M. Ramanathan, C. Montesinos, M. Jacobson, M. A. Schwarzschild, et al. 2002. Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. Am. J. Pathol. 160: 2231-2244.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 2231-2244
-
-
Leibovich, S.J.1
Chen, J.F.2
Pinhal-Enfield, G.3
Belem, P.C.4
Elson, G.5
Rosania, A.6
Ramanathan, M.7
Montesinos, C.8
Jacobson, M.9
Schwarzschild, M.A.10
-
44
-
-
84898735135
-
Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells
-
Yamaguchi, H., T. Maruyama, Y. Urade, and S. Nagata. 2014. Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells. eLife 3: e02172.
-
(2014)
ELife
, vol.3
, pp. e02172
-
-
Yamaguchi, H.1
Maruyama, T.2
Urade, Y.3
Nagata, S.4
-
45
-
-
23844468795
-
Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli
-
Pei, L., A. Castrillo, M. Chen, A. Hoffmann, and P. Tontonoz. 2005. Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli. J. Biol. Chem. 280: 29256-29262.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29256-29262
-
-
Pei, L.1
Castrillo, A.2
Chen, M.3
Hoffmann, A.4
Tontonoz, P.5
-
46
-
-
33645411885
-
Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77
-
Pei, L., A. Castrillo, and P. Tontonoz. 2006. Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. Mol. Endocrinol. 20: 786-794.
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 786-794
-
-
Pei, L.1
Castrillo, A.2
Tontonoz, P.3
-
47
-
-
84932186336
-
Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation
-
Li, L., Y. Liu, H. Z. Chen, F. W. Li, J. F. Wu, H. K. Zhang, J. P. He, Y. Z. Xing, Y. Chen, W. J. Wang, et al. 2015. Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat. Chem. Biol. 11: 339-346.
-
(2015)
Nat. Chem. Biol.
, vol.11
, pp. 339-346
-
-
Li, L.1
Liu, Y.2
Chen, H.Z.3
Li, F.W.4
Wu, J.F.5
Zhang, H.K.6
He, J.P.7
Xing, Y.Z.8
Chen, Y.9
Wang, W.J.10
-
48
-
-
78649512344
-
An immune paradox: How can the same chemokine axis regulate both immune tolerance and activation?: CCR6/CCL20: A chemokine axis balancing immunological tolerance and inflammation in autoimmune disease
-
Comerford, I., M. Bunting, K. Fenix, S. Haylock-Jacobs, W. Litchfield, Y. Harata-Lee, M. Turvey, J. Brazzatti, C. Gregor, P. Nguyen, et al. 2010. An immune paradox: how can the same chemokine axis regulate both immune tolerance and activation?: CCR6/CCL20: a chemokine axis balancing immunological tolerance and inflammation in autoimmune disease. BioEssays 32: 1067-1076.
-
(2010)
BioEssays
, vol.32
, pp. 1067-1076
-
-
Comerford, I.1
Bunting, M.2
Fenix, K.3
Haylock-Jacobs, S.4
Litchfield, W.5
Harata-Lee, Y.6
Turvey, M.7
Brazzatti, J.8
Gregor, C.9
Nguyen, P.10
-
49
-
-
34250351459
-
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
-
Deaglio, S., K. M. Dwyer, W. Gao, D. Friedman, A. Usheva, A. Erat, J. F. Chen, K. Enjyoji, J. Linden, M. Oukka, et al. 2007. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J. Exp. Med. 204: 1257-1265.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1257-1265
-
-
Deaglio, S.1
Dwyer, K.M.2
Gao, W.3
Friedman, D.4
Usheva, A.5
Erat, A.6
Chen, J.F.7
Enjyoji, K.8
Linden, J.9
Oukka, M.10
-
50
-
-
38049141544
-
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
-
Zarek, P. E., C. T. Huang, E. R. Lutz, J. Kowalski, M. R. Horton, J. Linden, C. G. Drake, and J. D. Powell. 2008. A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells. Blood 111: 251-259.
-
(2008)
Blood
, vol.111
, pp. 251-259
-
-
Zarek, P.E.1
Huang, C.T.2
Lutz, E.R.3
Kowalski, J.4
Horton, M.R.5
Linden, J.6
Drake, C.G.7
Powell, J.D.8
-
51
-
-
84857521504
-
Adora2b adenosine receptor engagement enhances regulatory T cell abundance during endotoxin-induced pulmonary inflammation
-
Ehrentraut, H., J. A. Westrich, H. K. Eltzschig, and E. T. Clambey. 2012. Adora2b adenosine receptor engagement enhances regulatory T cell abundance during endotoxin-induced pulmonary inflammation. PLoS ONE 7: e32416.
-
(2012)
PLoS ONE
, vol.7
, pp. e32416
-
-
Ehrentraut, H.1
Westrich, J.A.2
Eltzschig, H.K.3
Clambey, E.T.4
-
52
-
-
84907532412
-
Minireview: Role of orphan nuclear receptors in cancer and potential as drug targets
-
Safe, S., U. H. Jin, E. Hedrick, A. Reeder, and S. O. Lee. 2014. Minireview: role of orphan nuclear receptors in cancer and potential as drug targets. Mol. Endocrinol. 28: 157-172.
-
(2014)
Mol. Endocrinol.
, vol.28
, pp. 157-172
-
-
Safe, S.1
Jin, U.H.2
Hedrick, E.3
Reeder, A.4
Lee, S.O.5
-
53
-
-
77957329141
-
Minireview: Nuclear hormone receptor 4A signaling: Implications for metabolic disease
-
Pearen, M. A., and G. E. Muscat. 2010. Minireview: nuclear hormone receptor 4A signaling: implications for metabolic disease. Mol. Endocrinol. 24: 1891-1903.
-
(2010)
Mol. Endocrinol.
, vol.24
, pp. 1891-1903
-
-
Pearen, M.A.1
Muscat, G.E.2
-
54
-
-
84862545879
-
Molecular pathways: The role of NR4A orphan nuclear receptors in cancer
-
Mohan, H. M., C. M. Aherne, A. C. Rogers, A. W. Baird, D. C. Winter, and E. P. Murphy. 2012. Molecular pathways: the role of NR4A orphan nuclear receptors in cancer. Clin. Cancer Res. 18: 3223-3228.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 3223-3228
-
-
Mohan, H.M.1
Aherne, C.M.2
Rogers, A.C.3
Baird, A.W.4
Winter, D.C.5
Murphy, E.P.6
-
55
-
-
84938942947
-
The Nurr1 activator 1,1-bis(39-indolyl)-1-(pchlorophenyl) methane blocks inflammatory gene expression in BV-2 microglial cells by inhibiting nuclear factor kB
-
De Miranda, B. R., K. A. Popichak, S. L. Hammond, B. A. Jorgensen, A. T. Phillips, S. Safe, and R. B. Tjalkens. 2015. The Nurr1 activator 1,1-bis(39-indolyl)-1-(pchlorophenyl) methane blocks inflammatory gene expression in BV-2 microglial cells by inhibiting nuclear factor kB. Mol. Pharmacol. 87: 1021-1034.
-
(2015)
Mol. Pharmacol.
, vol.87
, pp. 1021-1034
-
-
De Miranda, B.R.1
Popichak, K.A.2
Hammond, S.L.3
Jorgensen, B.A.4
Phillips, A.T.5
Safe, S.6
Tjalkens, R.B.7
|