Transforming growth factor βactivated kinase 1 signaling pathway critically regulates myocardial survival and remodeling

Circulation

Volumn 130, Issue 24, 2014, Pages 2162-2172

  Li, Lei ^a   Chen, Yi ^a   Doan, Jessica ^a   Murray, Jason ^a   Molkentin, Jeffery D ^b   Liu, Qinghang ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

apoptosis; heart failure; myocytes, cardiac; necrosis; signal transduction; ventricular remodeling

Indexed keywords

CASPASE 8; FAS ASSOCIATED DEATH DOMAIN PROTEIN; PROTEIN; RECEPTOR INTERACTING PROTEIN 1; RECEPTOR INTERACTING PROTEIN 3; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG; FADD PROTEIN, MOUSE; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL SURVIVAL; CONTROLLED STUDY; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE NECROSIS; HEART VENTRICLE REMODELING; HOMEOSTASIS; MOUSE; NECROPTOSIS; NONHUMAN; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; CELL LINE; DEFICIENCY; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; MORTALITY; NECROSIS; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CASPASE 8; CELL LINE; DISEASE MODELS, ANIMAL; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HEART FAILURE; HOMEOSTASIS; MAP KINASE KINASE KINASES; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; NECROSIS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; VENTRICULAR REMODELING;

EID: 84918511539     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.114.011195     Document Type: Review

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