메뉴 건너뛰기




Volumn 23, Issue 5, 2016, Pages 469-478

Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction

Author keywords

[No Author keywords available]

Indexed keywords

GREEN FLUORESCENT PROTEIN; LUCIFERASE; MYOSIN HEAVY CHAIN; MYOSIN IIB; TRANSCRIPTION FACTOR RUNX2; CELL ADHESION MOLECULE; POSTN PROTEIN, HUMAN;

EID: 84961231312     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2016.20     Document Type: Article
Times cited : (41)

References (47)
  • 1
    • 33746874152 scopus 로고    scopus 로고
    • Adeno-associated virus serotypes: Vector toolkit for human gene therapy
    • Wu Z, Asokan A, Samulski R. Adeno-associated virus serotypes: vector toolkit for human gene therapy. Mol Ther 2006; 14: 316-327.
    • (2006) Mol Ther , vol.14 , pp. 316-327
    • Wu, Z.1    Asokan, A.2    Samulski, R.3
  • 2
    • 44349170706 scopus 로고    scopus 로고
    • Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection
    • Zincarelli C, Soltys S, Rengo G, Rabinowitz JE. Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection. Mol Ther 2008; 16: 1073-1080.
    • (2008) Mol Ther , vol.16 , pp. 1073-1080
    • Zincarelli, C.1    Soltys, S.2    Rengo, G.3    Rabinowitz, J.E.4
  • 3
    • 79959731191 scopus 로고    scopus 로고
    • A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction
    • Prasad K-MR, Smith RS, Xu Y, French BA. A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction. J Gene Med 2011; 13: 333-341.
    • (2011) J Gene Med , vol.13 , pp. 333-341
    • Prasad, K.-M.R.1    Smith, R.S.2    Xu, Y.3    French, B.A.4
  • 4
    • 33745143956 scopus 로고    scopus 로고
    • Robust systemic transduction with AAV9 vectors in mice: Efficient global cardiac gene transfer superior to that of AAV8
    • Inagaki K, Fuess S, Storm TA, Gibson GA, Mctiernan CF, Kay MA et al. Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. Mol Ther 2006; 14: 45-53.
    • (2006) Mol Ther , vol.14 , pp. 45-53
    • Inagaki, K.1    Fuess, S.2    Storm, T.A.3    Gibson, G.A.4    Mctiernan, C.F.5    Kay, M.A.6
  • 5
    • 0016250642 scopus 로고
    • Development and proliferative capacity of cardiac muscle cells
    • Zak R. Development and proliferative capacity of cardiac muscle cells. Circ Res 1974; 35(Suppl II): 17-26.
    • (1974) Circ Res , vol.35 , pp. 17-26
    • Zak, R.1
  • 6
    • 0019127308 scopus 로고
    • Study of non-muscle cells of the adult mammalian heart: A fine structural analysis and distribution
    • Nag A. Study of non-muscle cells of the adult mammalian heart: a fine structural analysis and distribution. Cytobios 1980; 28: 41-61.
    • (1980) Cytobios , vol.28 , pp. 41-61
    • Nag, A.1
  • 7
    • 73349122017 scopus 로고    scopus 로고
    • Cardiac fibroblast: The renaissance cell
    • Souders CA, Bowers SLK, Baudino TA. Cardiac fibroblast: the renaissance cell. Circ Res 2009; 105: 1164-1176.
    • (2009) Circ Res , vol.105 , pp. 1164-1176
    • Souders, C.A.1    Bowers, S.L.K.2    Baudino, T.A.3
  • 8
    • 34548423254 scopus 로고    scopus 로고
    • Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse
    • Banerjee I, Fuseler JW, Price RL, Borg TK, Baudino TA. Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am J Physiol Heart Circ Physiol 2007; 293: H1883-H1891.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293 , pp. H1883-H1891
    • Banerjee, I.1    Fuseler, J.W.2    Price, R.L.3    Borg, T.K.4    Baudino, T.A.5
  • 10
    • 33745739299 scopus 로고    scopus 로고
    • Targeting the inflammatory response in healing myocardial infarcts
    • Frangogiannis NG. Targeting the inflammatory response in healing myocardial infarcts. Curr Med Chem 2006; 13: 1877-1893.
    • (2006) Curr Med Chem , vol.13 , pp. 1877-1893
    • Frangogiannis, N.G.1
  • 11
    • 84868147722 scopus 로고    scopus 로고
    • Adenoassociated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling
    • Konkalmatt PR, Wang F, Piras BA, Xu Y, O'Connor DM, Beyers RJ et al. Adenoassociated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling. J Gene Med 2012; 14: 609-620.
    • (2012) J Gene Med , vol.14 , pp. 609-620
    • Konkalmatt, P.R.1    Wang, F.2    Piras, B.A.3    Xu, Y.4    O'Connor, D.M.5    Beyers, R.J.6
  • 12
    • 84880224247 scopus 로고    scopus 로고
    • Cardiacselective expression of extracellular superoxide dismutase after systemic injection of adeno-associated virus 9 protects the heart against post-myocardial infarction left ventricular remodeling
    • Konkalmatt PR, Beyers RJ, O'Connor DM, Xu Y, Seaman ME, French BA. Cardiacselective expression of extracellular superoxide dismutase after systemic injection of adeno-associated virus 9 protects the heart against post-myocardial infarction left ventricular remodeling. Circ Cardiovasc Imaging 2013; 6: 478-486.
    • (2013) Circ Cardiovasc Imaging , vol.6 , pp. 478-486
    • Konkalmatt, P.R.1    Beyers, R.J.2    O'Connor, D.M.3    Xu, Y.4    Seaman, M.E.5    French, B.A.6
  • 13
    • 73149120964 scopus 로고    scopus 로고
    • Transduction efficiency of AAV 2/6, 2/8 and 2/9 vectors for delivering genes in human corneal fibroblasts
    • Sharma A, Ghosh A, Hansen ET, Newman JM, Mohan RR. Transduction efficiency of AAV 2/6, 2/8 and 2/9 vectors for delivering genes in human corneal fibroblasts. Brain Res Bull 2010; 81: 273-278.
    • (2010) Brain Res Bull , vol.81 , pp. 273-278
    • Sharma, A.1    Ghosh, A.2    Hansen, E.T.3    Newman, J.M.4    Mohan, R.R.5
  • 14
    • 78650979325 scopus 로고    scopus 로고
    • Robust cardiomyocyte-specific gene expression following systemic injection of AAV: In vivo gene delivery follows a Poisson distribution
    • Prasad KMR, Xu Y, Yang Z, Acton ST, French BA. Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution. Gene Therapy 2011; 18: 43-52.
    • (2011) Gene Therapy , vol.18 , pp. 43-52
    • Prasad, K.M.R.1    Xu, Y.2    Yang, Z.3    Acton, S.T.4    French, B.A.5
  • 15
    • 34347214790 scopus 로고    scopus 로고
    • Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer
    • Lindsley A, Snider P, Zhou H, Rogers R, Wang J, Olaopa M et al. Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer. Dev Biol 2007; 307: 340-355.
    • (2007) Dev Biol , vol.307 , pp. 340-355
    • Lindsley, A.1    Snider, P.2    Zhou, H.3    Rogers, R.4    Wang, J.5    Olaopa, M.6
  • 16
    • 74949131620 scopus 로고    scopus 로고
    • Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload
    • Takeda N, Manabe I, Uchino Y, Eguchi K, Matsumoto S, Nishimura S et al. Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload. J Clin Invest 2010; 120: 254-265.
    • (2010) J Clin Invest , vol.120 , pp. 254-265
    • Takeda, N.1    Manabe, I.2    Uchino, Y.3    Eguchi, K.4    Matsumoto, S.5    Nishimura, S.6
  • 17
    • 39549107343 scopus 로고    scopus 로고
    • Periostin is essential for cardiac healing after acute myocardial infarction
    • Shimazaki M, Nakamura K, Kii I, Kashima T, Amizuka N, Li M et al. Periostin is essential for cardiac healing after acute myocardial infarction. J Exp Med 2008; 205: 295-303.
    • (2008) J Exp Med , vol.205 , pp. 295-303
    • Shimazaki, M.1    Nakamura, K.2    Kii, I.3    Kashima, T.4    Amizuka, N.5    Li, M.6
  • 18
    • 47149111304 scopus 로고    scopus 로고
    • Mechanisms of postinfarct left ventricular remodeling
    • French BA, Kramer CM. Mechanisms of postinfarct left ventricular remodeling. Drug Discov Today Dis Mech 2007; 4: 185-196.
    • (2007) Drug Discov Today Dis Mech , vol.4 , pp. 185-196
    • French, B.A.1    Kramer, C.M.2
  • 19
    • 0033776206 scopus 로고    scopus 로고
    • Myofibroblasts in reperfused myocardial infarcts express the embryonic form of smooth muscle myosin heavy chain (SMemb)
    • Frangogiannis NG, Michael LH, Entman ML. Myofibroblasts in reperfused myocardial infarcts express the embryonic form of smooth muscle myosin heavy chain (SMemb). Cardiovasc Res 2000; 48: 89-100.
    • (2000) Cardiovasc Res , vol.48 , pp. 89-100
    • Frangogiannis, N.G.1    Michael, L.H.2    Entman, M.L.3
  • 21
    • 34848893324 scopus 로고    scopus 로고
    • The participation of the Na+-Ca2+ exchanger in primary cardiac myofibroblast migration, contraction, and proliferation
    • Raizman JE, Komljenovic J, Chang R, Deng C, Bedosky KM, Rattan SG et al. The participation of the Na+-Ca2+ exchanger in primary cardiac myofibroblast migration, contraction, and proliferation. J Cell Physiol 2007; 213: 540-551.
    • (2007) J Cell Physiol , vol.213 , pp. 540-551
    • Raizman, J.E.1    Komljenovic, J.2    Chang, R.3    Deng, C.4    Bedosky, K.M.5    Rattan, S.G.6
  • 22
    • 77952717237 scopus 로고    scopus 로고
    • Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: Expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts
    • Santiago J-J, Dangerfield AL, Rattan SG, Bathe KL, Cunnington RH, Raizman JE et al. Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts. Dev Dyn 2010; 239: 1573-1584.
    • (2010) Dev Dyn , vol.239 , pp. 1573-1584
    • Santiago, J.-J.1    Dangerfield, A.L.2    Rattan, S.G.3    Bathe, K.L.4    Cunnington, R.H.5    Raizman, J.E.6
  • 23
    • 0036569318 scopus 로고    scopus 로고
    • Active interstitial remodeling: An important process in the hibernating human myocardium
    • Frangogiannis NG, Shimoni S, Chang S, Ren G, Dewald O, Gersch C et al. Active interstitial remodeling: an important process in the hibernating human myocardium. J Am Coll Cardiol 2002; 39: 1468-1474.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 1468-1474
    • Frangogiannis, N.G.1    Shimoni, S.2    Chang, S.3    Ren, G.4    Dewald, O.5    Gersch, C.6
  • 24
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
    • Ieda M, Fu J-D, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010; 142: 375-386.
    • (2010) Cell , vol.142 , pp. 375-386
    • Ieda, M.1    Fu, J.-D.2    Delgado-Olguin, P.3    Vedantham, V.4    Hayashi, Y.5    Bruneau, B.G.6
  • 25
    • 84867704611 scopus 로고    scopus 로고
    • Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5
    • Inagawa K, Miyamoto K, Yamakawa H, Muraoka N, Sadahiro T, Umei T et al. Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5. Circ Res 2012; 111: 1147-1156.
    • (2012) Circ Res , vol.111 , pp. 1147-1156
    • Inagawa, K.1    Miyamoto, K.2    Yamakawa, H.3    Muraoka, N.4    Sadahiro, T.5    Umei, T.6
  • 26
    • 84863629484 scopus 로고    scopus 로고
    • In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
    • Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 2012; 485: 593-598.
    • (2012) Nature , vol.485 , pp. 593-598
    • Qian, L.1    Huang, Y.2    Spencer, C.I.3    Foley, A.4    Vedantham, V.5    Liu, L.6
  • 27
    • 84861642380 scopus 로고    scopus 로고
    • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes
    • Jayawardena TM, Egemnazarov B, Finch EA, Zhang L, Payne JA, Pandya K et al. MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ Res 2012; 110: 1465-1473.
    • (2012) Circ Res , vol.110 , pp. 1465-1473
    • Jayawardena, T.M.1    Egemnazarov, B.2    Finch, E.A.3    Zhang, L.4    Payne, J.A.5    Pandya, K.6
  • 29
    • 34548371401 scopus 로고    scopus 로고
    • Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling
    • Oka T, Xu J, Kaiser RA, Melendez J, Hambleton M, Sargent MA et al. Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res 2007; 101: 313-321.
    • (2007) Circ Res , vol.101 , pp. 313-321
    • Oka, T.1    Xu, J.2    Kaiser, R.A.3    Melendez, J.4    Hambleton, M.5    Sargent, M.A.6
  • 30
    • 34547691243 scopus 로고    scopus 로고
    • Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair
    • Kühn B, del Monte F, Hajjar RJ, Chang Y-S, Lebeche D, Arab S et al. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med 2007; 13: 962-969.
    • (2007) Nat Med , vol.13 , pp. 962-969
    • Kühn, B.1    Del Monte, F.2    Hajjar, R.J.3    Chang, Y.-S.4    Lebeche, D.5    Arab, S.6
  • 31
    • 84899897293 scopus 로고    scopus 로고
    • Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair
    • Furtado MB, Costa MW, Pranoto EA, Salimova E, Pinto AR, Lam NT et al. Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair. Circ Res 2014; 114: 1422-1434.
    • (2014) Circ Res , vol.114 , pp. 1422-1434
    • Furtado, M.B.1    Costa, M.W.2    Pranoto, E.A.3    Salimova, E.4    Pinto, A.R.5    Lam, N.T.6
  • 32
    • 84929190546 scopus 로고    scopus 로고
    • Interacting resident epicardium-derived fibroblasts and recruited bone marrow cells form myocardial infarction scar
    • Ruiz-Villalba A, Simón AM, Pogontke C, Castillo MI, Abizanda G, Pelacho B et al. Interacting resident epicardium-derived fibroblasts and recruited bone marrow cells form myocardial infarction scar. J Am Coll Cardiol 2015; 65: 2057-2066.
    • (2015) J Am Coll Cardiol , vol.65 , pp. 2057-2066
    • Ruiz-Villalba, A.1    Simón, A.M.2    Pogontke, C.3    Castillo, M.I.4    Abizanda, G.5    Pelacho, B.6
  • 33
    • 84869083816 scopus 로고    scopus 로고
    • Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins
    • Lovric J, Mano M, Zentilin L, Eulalio A, Zacchigna S, Giacca M. Terminal differentiation of cardiac and skeletal myocytes induces permissivity to AAV transduction by relieving inhibition imposed by DNA damage response proteins. Mol Ther 2012; 20: 2087-2097.
    • (2012) Mol Ther , vol.20 , pp. 2087-2097
    • Lovric, J.1    Mano, M.2    Zentilin, L.3    Eulalio, A.4    Zacchigna, S.5    Giacca, M.6
  • 34
    • 36348963101 scopus 로고    scopus 로고
    • The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication
    • Schwartz RA, Palacios JA, Cassell GD, Adam S, Giacca M, Weitzman MD. The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication. J Virol 2007; 81: 12936-12945.
    • (2007) J Virol , vol.81 , pp. 12936-12945
    • Schwartz, R.A.1    Palacios, J.A.2    Cassell, G.D.3    Adam, S.4    Giacca, M.5    Weitzman, M.D.6
  • 35
    • 40549138765 scopus 로고    scopus 로고
    • Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins
    • Cervelli T, Palacios JA, Zentilin L, Mano M, Schwartz RA, Weitzman MD et al. Processing of recombinant AAV genomes occurs in specific nuclear structures that overlap with foci of DNA-damage-response proteins. J Cell Sci 2008; 121: 349-357.
    • (2008) J Cell Sci , vol.121 , pp. 349-357
    • Cervelli, T.1    Palacios, J.A.2    Zentilin, L.3    Mano, M.4    Schwartz, R.A.5    Weitzman, M.D.6
  • 37
    • 0028173386 scopus 로고
    • The alpha-smooth muscle actin-positive cells in healing human myocardial scars
    • Willems IE, Havenith MG, De Mey JG, Daemen MJ. The alpha-smooth muscle actin-positive cells in healing human myocardial scars. Am J Pathol 1994; 145: 868-875.
    • (1994) Am J Pathol , vol.145 , pp. 868-875
    • Willems, I.E.1    Havenith, M.G.2    De Mey, J.G.3    Daemen, M.J.4
  • 38
    • 0036266753 scopus 로고    scopus 로고
    • Serial MRI evaluation of cardiac structure and function in mice after reperfused myocardial infarction
    • Ross A, Yang Z, Berr S, Gilson W, Petersen W, Oshinski J et al. Serial MRI evaluation of cardiac structure and function in mice after reperfused myocardial infarction. Magn Reson Med 2002; 47: 1158-1168.
    • (2002) Magn Reson Med , vol.47 , pp. 1158-1168
    • Ross, A.1    Yang, Z.2    Berr, S.3    Gilson, W.4    Petersen, W.5    Oshinski, J.6
  • 40
    • 79951510234 scopus 로고    scopus 로고
    • MicroRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors
    • Geisler A, Jungmann A, Kurreck J, Poller W, Katus HA, Vetter R et al. microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors. Gene Therapy 2010; 18: 199-209.
    • (2010) Gene Therapy , vol.18 , pp. 199-209
    • Geisler, A.1    Jungmann, A.2    Kurreck, J.3    Poller, W.4    Katus, H.A.5    Vetter, R.6
  • 41
    • 79953803239 scopus 로고    scopus 로고
    • Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver
    • Qiao C, Yuan Z, Li J, He B, Zheng H, Mayer C et al. Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver. Gene Therapy 2010; 18: 403-410.
    • (2010) Gene Therapy , vol.18 , pp. 403-410
    • Qiao, C.1    Yuan, Z.2    Li, J.3    He, B.4    Zheng, H.5    Mayer, C.6
  • 42
    • 73949140059 scopus 로고    scopus 로고
    • A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
    • Madisen L, Zwingman TA, Sunkin SM, Oh SW, Zariwala HA, Gu H et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci 2010; 13: 133-140.
    • (2010) Nat Neurosci , vol.13 , pp. 133-140
    • Madisen, L.1    Zwingman, T.A.2    Sunkin, S.M.3    Oh, S.W.4    Zariwala, H.A.5    Gu, H.6
  • 43
    • 1642516133 scopus 로고    scopus 로고
    • Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination
    • Safran M, Kim WY, Kung AL, Horner JW, DePinho RA, Kaelin WG Jr. Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination. Mol Imaging 2003; 2: 297-302.
    • (2003) Mol Imaging , vol.2 , pp. 297-302
    • Safran, M.1    Kim, W.Y.2    Kung, A.L.3    Horner, J.W.4    DePinho, R.A.5    Kaelin, W.G.6
  • 45
    • 33947288478 scopus 로고    scopus 로고
    • Topoisomerase inhibition accelerates gene expression after adeno-associated virus-mediated gene transfer to the mammalian heart
    • Prasad K-MR, Xu Y, Yang Z, Toufektsian M-C, Berr SS, French BA. Topoisomerase inhibition accelerates gene expression after adeno-associated virus-mediated gene transfer to the mammalian heart. Mol Ther 2007; 15: 764-771.
    • (2007) Mol Ther , vol.15 , pp. 764-771
    • Prasad, K.-M.R.1    Xu, Y.2    Yang, Z.3    Toufektsian, M.-C.4    Berr, S.S.5    French, B.A.6
  • 46
    • 0027713229 scopus 로고
    • Gene therapy by intramuscular injection of plasmid DNA: Studies on firefly luciferase gene expression in mice
    • Manthorpe M, Cornefert-Jensen F, Hartikka J, Felgner J, Rundell A, Margalith M et al. Gene therapy by intramuscular injection of plasmid DNA: studies on firefly luciferase gene expression in mice. Hum Gene Ther 1993; 4: 419-431.
    • (1993) Hum Gene Ther , vol.4 , pp. 419-431
    • Manthorpe, M.1    Cornefert-Jensen, F.2    Hartikka, J.3    Felgner, J.4    Rundell, A.5    Margalith, M.6
  • 47
    • 0019402092 scopus 로고
    • Autofluorescence in the identification of myocardial infarcts
    • Carle BN. Autofluorescence in the identification of myocardial infarcts. Hum Pathol 1981; 12: 643-646.
    • (1981) Hum Pathol , vol.12 , pp. 643-646
    • Carle, B.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.