-
2
-
-
84880757177
-
Deciphering and Reversing Tumor Immune Suppression
-
Motz GT and Coukos G. Deciphering and Reversing Tumor Immune Suppression. Immunity. 2013; 39:61-73.
-
(2013)
Immunity
, vol.39
, pp. 61-73
-
-
Motz, G.T.1
Coukos, G.2
-
3
-
-
84908497841
-
Translational research in oncology-10 years of progress and future prospects
-
Doroshow JH and Kummar S. Translational research in oncology-10 years of progress and future prospects. Nat Rev Clin Oncol. 2014; 11:649-662.
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 649-662
-
-
Doroshow, J.H.1
Kummar, S.2
-
4
-
-
84928759208
-
Adoptive cell transfer as personalized immunotherapy for human cancer
-
Rosenberg SA and Restifo NP. Adoptive cell transfer as personalized immunotherapy for human cancer. Science. 2015; 348:62-68.
-
(2015)
Science
, vol.348
, pp. 62-68
-
-
Rosenberg, S.A.1
Restifo, N.P.2
-
5
-
-
84921418427
-
Classification of current anticancer immunotherapies
-
Galluzzi L, Vacchelli E, Bravo-San Pedro JM, Buque A, Senovilla L, Baracco EE, Bloy N, Castoldi F, Abastado JP, Agostinis P, Apte RN, Aranda F, Ayyoub M, et al. Classification of current anticancer immunotherapies. Oncotarget. 2014; 5:12472-12508. doi:10.18632/oncotarget.2998.
-
(2014)
Oncotarget
, vol.5
, pp. 12472-12508
-
-
Galluzzi, L.1
Vacchelli, E.2
Bravo-San Pedro, J.M.3
Buque, A.4
Senovilla, L.5
Baracco, E.E.6
Bloy, N.7
Castoldi, F.8
Abastado, J.P.9
Agostinis, P.10
Apte, R.N.11
Aranda, F.12
Ayyoub, M.13
-
6
-
-
80053903082
-
In vivo modulation of dendritic cells by engineered materials: Towards new cancer vaccines
-
Kim J and Mooney DJ. In vivo modulation of dendritic cells by engineered materials: Towards new cancer vaccines. Nano Today. 2011; 6:466-477.
-
(2011)
Nano Today
, vol.6
, pp. 466-477
-
-
Kim, J.1
Mooney, D.J.2
-
7
-
-
84931060402
-
Biomaterials for Nanoparticle Vaccine Delivery Systems
-
Sahdev P, Ochyl LJ and Moon JJ. Biomaterials for Nanoparticle Vaccine Delivery Systems. Pharm Res-Dordr. 2014; 31:2563-2582.
-
(2014)
Pharm Res-Dordr
, vol.31
, pp. 2563-2582
-
-
Sahdev, P.1
Ochyl, L.J.2
Moon, J.J.3
-
8
-
-
84941254141
-
Increasing disparities between resource inputs and outcomes, as measured by certain health deliverables, in biomedical research
-
Bowen A and Casadevall A. Increasing disparities between resource inputs and outcomes, as measured by certain health deliverables, in biomedical research. P Natl Acad Sci USA. 2015; 112:11335-11340.
-
(2015)
P Natl Acad Sci USA
, vol.112
, pp. 11335-11340
-
-
Bowen, A.1
Casadevall, A.2
-
9
-
-
84941053743
-
Hydrogels and Scaffolds for Immunomodulation
-
Singh A and Peppas NA. Hydrogels and Scaffolds for Immunomodulation. Adv Mater. 2014; 26:6530-6541.
-
(2014)
Adv Mater
, vol.26
, pp. 6530-6541
-
-
Singh, A.1
Peppas, N.A.2
-
10
-
-
84961289256
-
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy
-
Kim J, Li WA, Choi Y, Lewin SA, Verbeke CS, Dranoff G and Mooney DJ. Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy. Nat Biotechnol. 2015; 33:64-U241.
-
(2015)
Nat Biotechnol
, vol.33
, pp. U64-U241
-
-
Kim, J.1
Li, W.A.2
Choi, Y.3
Lewin, S.A.4
Verbeke, C.S.5
Dranoff, G.6
Mooney, D.J.7
-
11
-
-
84923815724
-
Tunable Nanostructured Coating for the Capture and Selective Release of Viable Circulating Tumor Cells
-
Reategui E, Aceto N, Lim EJ, Sullivan JP, Jensen AE, Zeinali M, Martel JM, Aranyosi AJ, Li W, Castleberry S, Bardia A, Sequist LV, Haber DA, Maheswaran S, Hammond PT, Toner M, et al. Tunable Nanostructured Coating for the Capture and Selective Release of Viable Circulating Tumor Cells. Adv Mater. 2015; 27:1593-1599.
-
(2015)
Adv Mater
, vol.27
, pp. 1593-1599
-
-
Reategui, E.1
Aceto, N.2
Lim, E.J.3
Sullivan, J.P.4
Jensen, A.E.5
Zeinali, M.6
Martel, J.M.7
Aranyosi, A.J.8
Li, W.9
Castleberry, S.10
Bardia, A.11
Sequist, L.V.12
Haber, D.A.13
Maheswaran, S.14
Hammond, P.T.15
Toner, M.16
-
13
-
-
84921758059
-
Nanoparticle-Based Immunotherapy for Cancer
-
Shao K, Singha S, Clemente-Casares X, Tsai S, Yang Y and Santamaria P. Nanoparticle-Based Immunotherapy for Cancer. Acs Nano. 2015; 9:16-30.
-
(2015)
Acs Nano
, vol.9
, pp. 16-30
-
-
Shao, K.1
Singha, S.2
Clemente-Casares, X.3
Tsai, S.4
Yang, Y.5
Santamaria, P.6
-
14
-
-
79953054576
-
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
-
Fang J, Nakamura H and Maeda H. The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Deliver Rev. 2011; 63:136-151.
-
(2011)
Adv Drug Deliver Rev
, vol.63
, pp. 136-151
-
-
Fang, J.1
Nakamura, H.2
Maeda, H.3
-
15
-
-
79953053224
-
Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects
-
Maruyama K. Intracellular targeting delivery of liposomal drugs to solid tumors based on EPR effects. Adv Drug Deliver Rev. 2011; 63:161-169.
-
(2011)
Adv Drug Deliver Rev
, vol.63
, pp. 161-169
-
-
Maruyama, K.1
-
16
-
-
84930208960
-
Harnessing Biomaterials to Engineer the Lymph Node Microenvironment for Immunity or Tolerance
-
Andorko JI, Hess KL and Jewell CM. Harnessing Biomaterials to Engineer the Lymph Node Microenvironment for Immunity or Tolerance. Aaps J. 2015; 17:323-338.
-
(2015)
Aaps J
, vol.17
, pp. 323-338
-
-
Andorko, J.I.1
Hess, K.L.2
Jewell, C.M.3
-
17
-
-
58849160540
-
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
-
Sharp FA, Ruane D, Claass B, Creagh E, Harris J, Malyala P, Singh M, O'Hagan DT, Petrilli V, Tschopp J, O'Neill LAJ and Lavelle EC. Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome. P Natl Acad Sci USA. 2009; 106:870-875.
-
(2009)
P Natl Acad Sci USA
, vol.106
, pp. 870-875
-
-
Sharp, F.A.1
Ruane, D.2
Claass, B.3
Creagh, E.4
Harris, J.5
Malyala, P.6
Singh, M.7
O'Hagan, D.T.8
Petrilli, V.9
Tschopp, J.10
O'Neill, L.A.J.11
Lavelle, E.C.12
-
19
-
-
84904728915
-
Gradated assembly of multiple proteins into supramolecular nanomaterials
-
Hudalla GA, Sun T, Gasiorowski JZ, Han H, Tian YF, Chong AS and Collier JH. Gradated assembly of multiple proteins into supramolecular nanomaterials. Nature materials. 2014; 13:829-836.
-
(2014)
Nature materials
, vol.13
, pp. 829-836
-
-
Hudalla, G.A.1
Sun, T.2
Gasiorowski, J.Z.3
Han, H.4
Tian, Y.F.5
Chong, A.S.6
Collier, J.H.7
-
20
-
-
84934947928
-
Polyelectrolyte Multilayers Assembled Entirely from Immune Signals on Gold Nanoparticle Templates Promote Antigen-Specific T Cell Response
-
Zhang P, Chiu YC, Tostanoski LH and Jewell CM. Polyelectrolyte Multilayers Assembled Entirely from Immune Signals on Gold Nanoparticle Templates Promote Antigen-Specific T Cell Response. Acs Nano. 2015; 9:6465-6477.
-
(2015)
Acs Nano
, vol.9
, pp. 6465-6477
-
-
Zhang, P.1
Chiu, Y.C.2
Tostanoski, L.H.3
Jewell, C.M.4
-
22
-
-
84873275186
-
Cancer nanomedicines: So many papers and so few drugs!
-
Venditto VJ and Szoka FC. Cancer nanomedicines: So many papers and so few drugs! Adv Drug Deliver Rev. 2013; 65:80-88.
-
(2013)
Adv Drug Deliver Rev
, vol.65
, pp. 80-88
-
-
Venditto, V.J.1
Szoka, F.C.2
-
23
-
-
84869103855
-
Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities
-
Cheng ZL, Al Zaki A, Hui JZ, Muzykantov VR and Tsourkas A. Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities. Science. 2012; 338:903-910.
-
(2012)
Science
, vol.338
, pp. 903-910
-
-
Cheng, Z.L.1
Al Zaki, A.2
Hui, J.Z.3
Muzykantov, V.R.4
Tsourkas, A.5
-
24
-
-
84875178629
-
Nanomedicine: is the wave cresting?
-
Juliano R. Nanomedicine: is the wave cresting? Nat Rev Drug Discov. 2013; 12:171-172.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 171-172
-
-
Juliano, R.1
-
25
-
-
84945894031
-
Is Nano a Bubble?
-
Möhwald H and Weiss PS. Is Nano a Bubble? Acs Nano. 2015; 9:9427-9428.
-
(2015)
Acs Nano
, vol.9
, pp. 9427-9428
-
-
Möhwald, H.1
Weiss, P.S.2
-
26
-
-
56749180605
-
Immunotherapy of autoimmunity and cancer: the penalty for success
-
Caspi RR. Immunotherapy of autoimmunity and cancer: the penalty for success. Nat Rev Immunol. 2008; 8:970-976.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 970-976
-
-
Caspi, R.R.1
-
28
-
-
79960635999
-
Effect of vesicle size on tissue localization and immunogenicity of liposomal DNA vaccines
-
Carstens MG, Camps MGM, Henriksen-Lacey M, Franken K, Ottenhoff THM, Perrie Y, Bouwstra JA, Ossendorp F and Jiskoot W. Effect of vesicle size on tissue localization and immunogenicity of liposomal DNA vaccines. Vaccine. 2011; 29:4761-4770.
-
(2011)
Vaccine
, vol.29
, pp. 4761-4770
-
-
Carstens, M.G.1
Camps, M.G.M.2
Henriksen-Lacey, M.3
Franken, K.4
Ottenhoff, T.H.M.5
Perrie, Y.6
Bouwstra, J.A.7
Ossendorp, F.8
Jiskoot, W.9
-
29
-
-
84874834355
-
Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity
-
Kwong B, Gai SA, Elkhader J, Wittrup KD and Irvine DJ. Localized Immunotherapy via Liposome-Anchored Anti-CD137 + IL-2 Prevents Lethal Toxicity and Elicits Local and Systemic Antitumor Immunity. Cancer Research. 2013; 73:1547-1558.
-
(2013)
Cancer Research
, vol.73
, pp. 1547-1558
-
-
Kwong, B.1
Gai, S.A.2
Elkhader, J.3
Wittrup, K.D.4
Irvine, D.J.5
-
30
-
-
79956132304
-
Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy
-
Kwong B, Liu H and Irvine DJ. Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy. Biomaterials. 2011; 32:5134-5147.
-
(2011)
Biomaterials
, vol.32
, pp. 5134-5147
-
-
Kwong, B.1
Liu, H.2
Irvine, D.J.3
-
31
-
-
84885023432
-
Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis
-
Wang Y, Xu Z, Guo S, Zhang L, Sharma A, Robertson GP and Huang L. Intravenous delivery of siRNA targeting CD47 effectively inhibits melanoma tumor growth and lung metastasis. Molecular therapy : the journal of the American Society of Gene Therapy. 2013; 21:1919-1929.
-
(2013)
Molecular therapy : the journal of the American Society of Gene Therapy
, vol.21
, pp. 1919-1929
-
-
Wang, Y.1
Xu, Z.2
Guo, S.3
Zhang, L.4
Sharma, A.5
Robertson, G.P.6
Huang, L.7
-
32
-
-
84889650175
-
Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose
-
de Titta A, Ballester M, Julier Z, Nembrini C, Jeanbart L, van der Vlies AJ, Swartz MA and Hubbell JA. Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose. Proc Natl Acad Sci U S A. 2013; 110:19902-19907.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 19902-19907
-
-
de Titta, A.1
Ballester, M.2
Julier, Z.3
Nembrini, C.4
Jeanbart, L.5
van der Vlies, A.J.6
Swartz, M.A.7
Hubbell, J.A.8
-
33
-
-
84872679360
-
Antigen-coated poly α-hydroxy acid based microparticles for heterologous prime-boost adenovirus based vaccinations
-
Lemke CD, Geary SM, Joshi VB and Salem AK. Antigen-coated poly α-hydroxy acid based microparticles for heterologous prime-boost adenovirus based vaccinations. Biomaterials. 2013; 34:2524-2529.
-
(2013)
Biomaterials
, vol.34
, pp. 2524-2529
-
-
Lemke, C.D.1
Geary, S.M.2
Joshi, V.B.3
Salem, A.K.4
-
34
-
-
84930388443
-
Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants
-
Hanson MC, Crespo MP, Abraham W, Moynihan KD, Szeto GL, Chen SH, Melo MB, Mueller S and Irvine DJ. Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants. Journal of Clinical Investigation. 2015; 125:2532-2546.
-
(2015)
Journal of Clinical Investigation
, vol.125
, pp. 2532-2546
-
-
Hanson, M.C.1
Crespo, M.P.2
Abraham, W.3
Moynihan, K.D.4
Szeto, G.L.5
Chen, S.H.6
Melo, M.B.7
Mueller, S.8
Irvine, D.J.9
-
35
-
-
84961288005
-
Immunomodulatory spherical nucleic acids
-
Radovic-Moreno AF, Chernyak N, Mader CC, Nallagatla S, Kang RS, Hao LL, Walker DA, Halo TL, Merkel TJ, Rische CH, Anantatmula S, Burkhart M, Mirkin CA and Gryaznov SM. Immunomodulatory spherical nucleic acids. P Natl Acad Sci USA. 2015; 112:3892-3897.
-
(2015)
P Natl Acad Sci USA
, vol.112
, pp. 3892-3897
-
-
Radovic-Moreno, A.F.1
Chernyak, N.2
Mader, C.C.3
Nallagatla, S.4
Kang, R.S.5
Hao, L.L.6
Walker, D.A.7
Halo, T.L.8
Merkel, T.J.9
Rische, C.H.10
Anantatmula, S.11
Burkhart, M.12
Mirkin, C.A.13
Gryaznov, S.M.14
-
36
-
-
70349854888
-
Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy
-
Hori Y, Stern PJ, Hynes RO and Irvine DJ. Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy. Biomaterials. 2009; 30:6757-6767.
-
(2009)
Biomaterials
, vol.30
, pp. 6757-6767
-
-
Hori, Y.1
Stern, P.J.2
Hynes, R.O.3
Irvine, D.J.4
-
37
-
-
84874592204
-
Retaining Antibodies in Tumors with a Self-Assembling Injectable System
-
Wen Y, Kolonich HR, Kruszewski KM, Giannoukakis N, Gawalt ES and Meng WS. Retaining Antibodies in Tumors with a Self-Assembling Injectable System. Molecular Pharmaceutics. 2013; 10:1035-1044.
-
(2013)
Molecular Pharmaceutics
, vol.10
, pp. 1035-1044
-
-
Wen, Y.1
Kolonich, H.R.2
Kruszewski, K.M.3
Giannoukakis, N.4
Gawalt, E.S.5
Meng, W.S.6
-
38
-
-
79551484727
-
Immunostimulatory sutures that treat local disease recurrence following primary tumor resection
-
011001
-
Intra J, Zhang XQ, Williams RL, Zhu X, Sandler AD and Salem AK. Immunostimulatory sutures that treat local disease recurrence following primary tumor resection. Biomedical materials. 2011; 6:011001.
-
(2011)
Biomedical materials
, vol.6
-
-
Intra, J.1
Zhang, X.Q.2
Williams, R.L.3
Zhu, X.4
Sandler, A.D.5
Salem, A.K.6
-
39
-
-
84897954314
-
Structure-based programming of lymph-node targeting in molecular vaccines
-
Liu H, Moynihan KD, Zheng Y, Szeto GL, Li AV, Huang B, Van Egeren DS, Park C and Irvine DJ. Structure-based programming of lymph-node targeting in molecular vaccines. Nature. 2014; 507:519-522.
-
(2014)
Nature
, vol.507
, pp. 519-522
-
-
Liu, H.1
Moynihan, K.D.2
Zheng, Y.3
Szeto, G.L.4
Li, A.V.5
Huang, B.6
Van Egeren, D.S.7
Park, C.8
Irvine, D.J.9
-
40
-
-
84938812163
-
Neoadjuvant immunotherapy with chitosan and interleukin-12 to control breast cancer metastasis
-
Vo JL, Yang L, Kurtz SL, Smith SG, Koppolu BP, Ravindranathan S and Zaharoff DA. Neoadjuvant immunotherapy with chitosan and interleukin-12 to control breast cancer metastasis. Oncoimmunology. 2014; 3:e968001-e968001.
-
(2014)
Oncoimmunology
, vol.3
, pp. e968001-e968001
-
-
Vo, J.L.1
Yang, L.2
Kurtz, S.L.3
Smith, S.G.4
Koppolu, B.P.5
Ravindranathan, S.6
Zaharoff, D.A.7
-
41
-
-
84971625868
-
Adoptive T cell therapy: Grand challenges and opportunities
-
June CH. Adoptive T cell therapy: Grand challenges and opportunities. J Immunother. 2007; 30:858-858.
-
(2007)
J Immunother
, vol.30
, pp. 858-858
-
-
June, C.H.1
-
42
-
-
84905864143
-
A carbon nanotube-polymer composite for T-cell therapy
-
Fadel TR, Sharp FA, Vudattu N, Ragheb R, Garyu J, Kim D, Hong E, Li N, Haller GL, Pfefferle LD, Justesen S, Herold KC and Fahmy TM. A carbon nanotube-polymer composite for T-cell therapy. Nature nanotechnology. 2014; 9:639-647.
-
(2014)
Nature nanotechnology
, vol.9
, pp. 639-647
-
-
Fadel, T.R.1
Sharp, F.A.2
Vudattu, N.3
Ragheb, R.4
Garyu, J.5
Kim, D.6
Hong, E.7
Li, N.8
Haller, G.L.9
Pfefferle, L.D.10
Justesen, S.11
Herold, K.C.12
Fahmy, T.M.13
-
43
-
-
84938151049
-
Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy
-
Perica K, Bieler JG, Schutz C, Varela JC, Douglass J, Skora A, Chiu YL, Oelke M, Kinzler K, Zhou SB, Vogelstein B and Schneck JP. Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy. Acs Nano. 2015; 9:6861-6871.
-
(2015)
Acs Nano
, vol.9
, pp. 6861-6871
-
-
Perica, K.1
Bieler, J.G.2
Schutz, C.3
Varela, J.C.4
Douglass, J.5
Skora, A.6
Chiu, Y.L.7
Oelke, M.8
Kinzler, K.9
Zhou, S.B.10
Vogelstein, B.11
Schneck, J.P.12
-
44
-
-
84897144168
-
Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8(+) T cells
-
Wolfl M and Greenberg PD. Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8(+) T cells. Nat Protoc. 2014; 9:950-966.
-
(2014)
Nat Protoc
, vol.9
, pp. 950-966
-
-
Wolfl, M.1
Greenberg, P.D.2
-
45
-
-
77956428880
-
Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
-
Stephan MT, Moon JJ, Um SH, Bershteyn A and Irvine DJ. Therapeutic cell engineering with surface-conjugated synthetic nanoparticles. Nature medicine. 2010; 16:1035-1041.
-
(2010)
Nature medicine
, vol.16
, pp. 1035-1041
-
-
Stephan, M.T.1
Moon, J.J.2
Um, S.H.3
Bershteyn, A.4
Irvine, D.J.5
-
46
-
-
84861348645
-
Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles
-
Stephan MT, Stephan SB, Bak P, Chen J and Irvine DJ. Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles. Biomaterials. 2012; 33:5776-5787.
-
(2012)
Biomaterials
, vol.33
, pp. 5776-5787
-
-
Stephan, M.T.1
Stephan, S.B.2
Bak, P.3
Chen, J.4
Irvine, D.J.5
-
47
-
-
84887121506
-
In vivo targeting of adoptively transferred T-cells with antibody-and cytokine-conjugated liposomes
-
Zheng Y, Stephan MT, Gai SA, Abraham W, Shearer A and Irvine DJ. In vivo targeting of adoptively transferred T-cells with antibody-and cytokine-conjugated liposomes. Journal of controlled release : official journal of the Controlled Release Society. 2013; 172:426-435.
-
(2013)
Journal of controlled release : official journal of the Controlled Release Society
, vol.172
, pp. 426-435
-
-
Zheng, Y.1
Stephan, M.T.2
Gai, S.A.3
Abraham, W.4
Shearer, A.5
Irvine, D.J.6
-
48
-
-
61849153316
-
SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels
-
Lorenz U. SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels. Immunol Rev. 2009; 228:342-359.
-
(2009)
Immunol Rev
, vol.228
, pp. 342-359
-
-
Lorenz, U.1
-
49
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012; 12:252-264.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
50
-
-
84927130807
-
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
-
Sharma P and Allison JP. Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential. Cell. 2015; 161:205-214.
-
(2015)
Cell
, vol.161
, pp. 205-214
-
-
Sharma, P.1
Allison, J.P.2
-
51
-
-
84922664081
-
Biopolymer implants enhance the efficacy of adoptive T-cell therapy
-
Stephan SB, Taber AM, Jileaeva I, Pegues EP, Sentman CL and Stephan MT. Biopolymer implants enhance the efficacy of adoptive T-cell therapy. Nat Biotechnol. 2015; 33:97-101.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 97-101
-
-
Stephan, S.B.1
Taber, A.M.2
Jileaeva, I.3
Pegues, E.P.4
Sentman, C.L.5
Stephan, M.T.6
-
52
-
-
84899489828
-
The effect of combined IL10 siRNA and CpG ODN as pathogen-mimicking microparticles on Th1/Th2 cytokine balance in dendritic cells and protective immunity against B cell lymphoma
-
Pradhan P, Qin H, Leleux JA, Gwak D, Sakamaki I, Kwak LW and Roy K. The effect of combined IL10 siRNA and CpG ODN as pathogen-mimicking microparticles on Th1/Th2 cytokine balance in dendritic cells and protective immunity against B cell lymphoma. Biomaterials. 2014; 35:5491-5504.
-
(2014)
Biomaterials
, vol.35
, pp. 5491-5504
-
-
Pradhan, P.1
Qin, H.2
Leleux, J.A.3
Gwak, D.4
Sakamaki, I.5
Kwak, L.W.6
Roy, K.7
-
53
-
-
80054095576
-
An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma
-
Singh A, Qin H, Fernandez I, Wei J, Lin J, Kwak LW and Roy K. An injectable synthetic immune-priming center mediates efficient T-cell class switching and T-helper 1 response against B cell lymphoma. Journal of controlled release : official journal of the Controlled Release Society. 2011; 155:184-192.
-
(2011)
Journal of controlled release : official journal of the Controlled Release Society
, vol.155
, pp. 184-192
-
-
Singh, A.1
Qin, H.2
Fernandez, I.3
Wei, J.4
Lin, J.5
Kwak, L.W.6
Roy, K.7
-
54
-
-
84930417773
-
Intravesical chitosan/interleukin-12 immunotherapy induces tumor-specific systemic immunity against murine bladder cancer
-
Smith SG, Koppolu BP, Ravindranathan S, Kurtz SL, Yang L, Katz MD and Zaharoff DA. Intravesical chitosan/interleukin-12 immunotherapy induces tumor-specific systemic immunity against murine bladder cancer. Cancer immunology, immunotherapy : CII. 2015; 64:689-696.
-
(2015)
Cancer immunology, immunotherapy : CII
, vol.64
, pp. 689-696
-
-
Smith, S.G.1
Koppolu, B.P.2
Ravindranathan, S.3
Kurtz, S.L.4
Yang, L.5
Katz, M.D.6
Zaharoff, D.A.7
-
55
-
-
68049147574
-
Intravesical immunotherapy of superficial bladder cancer with chitosan/interleukin-12
-
Zaharoff DA, Hoffman BS, Hooper HB, Benjamin CJ, Jr., Khurana KK, Hance KW, Rogers CJ, Pinto PA, Schlom J and Greiner JW. Intravesical immunotherapy of superficial bladder cancer with chitosan/interleukin-12. Cancer Res. 2009; 69:6192-6199.
-
(2009)
Cancer Res
, vol.69
, pp. 6192-6199
-
-
Zaharoff, D.A.1
Hoffman, B.S.2
Hooper, H.B.3
Benjamin, C.J.4
Khurana, K.K.5
Hance, K.W.6
Rogers, C.J.7
Pinto, P.A.8
Schlom, J.9
Greiner, J.W.10
-
56
-
-
84890171728
-
Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy
-
Crompton JG, Sukumar M and Restifo NP. Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy. Immunol Rev. 2014; 257:264-276.
-
(2014)
Immunol Rev
, vol.257
, pp. 264-276
-
-
Crompton, J.G.1
Sukumar, M.2
Restifo, N.P.3
-
57
-
-
20444499355
-
+ T cells
-
+ T cells. The Journal of clinical investigation. 2005; 115:1616-1626.
-
(2005)
The Journal of clinical investigation
, vol.115
, pp. 1616-1626
-
-
Gattinoni, L.1
Klebanoff, C.A.2
Palmer, D.C.3
Wrzesinski, C.4
Kerstann, K.5
Yu, Z.6
Finkelstein, S.E.7
Theoret, M.R.8
Rosenberg, S.A.9
Restifo, N.P.10
-
58
-
-
84859838781
-
Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype
-
Demento SL, Cui W, Criscione JM, Stern E, Tulipan J, Kaech SM and Fahmy TM. Role of sustained antigen release from nanoparticle vaccines in shaping the T cell memory phenotype. Biomaterials. 2012; 33:4957-4964.
-
(2012)
Biomaterials
, vol.33
, pp. 4957-4964
-
-
Demento, S.L.1
Cui, W.2
Criscione, J.M.3
Stern, E.4
Tulipan, J.5
Kaech, S.M.6
Fahmy, T.M.7
-
59
-
-
67650074206
-
mTOR regulates memory CD8 T-cell differentiation
-
Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF, Larsen CP and Ahmed R. mTOR regulates memory CD8 T-cell differentiation. Nature. 2009; 460:108-U124.
-
(2009)
Nature
, vol.460
, pp. U108-U124
-
-
Araki, K.1
Turner, A.P.2
Shaffer, V.O.3
Gangappa, S.4
Keller, S.A.5
Bachmann, M.F.6
Larsen, C.P.7
Ahmed, R.8
-
60
-
-
19944434230
-
Synergy of IL-21 and IL-15 in regulating CD8(+) T cell expansion and function
-
Zeng R, Spolski R, Finkelstein SE, Oh SK, Kovanen PE, Hinrichs CS, Pise-Masison CA, Radonovich MF, Brady JN, Restifo NP, Berzofsky JA and Leonard WJ. Synergy of IL-21 and IL-15 in regulating CD8(+) T cell expansion and function. J Exp Med. 2005; 201:139-148.
-
(2005)
J Exp Med
, vol.201
, pp. 139-148
-
-
Zeng, R.1
Spolski, R.2
Finkelstein, S.E.3
Oh, S.K.4
Kovanen, P.E.5
Hinrichs, C.S.6
Pise-Masison, C.A.7
Radonovich, M.F.8
Brady, J.N.9
Restifo, N.P.10
Berzofsky, J.A.11
Leonard, W.J.12
-
61
-
-
84907086036
-
Critical role of STAT3 in melanoma metastasis through anoikis resistance
-
Fofaria NM and Srivastava SK. Critical role of STAT3 in melanoma metastasis through anoikis resistance. Oncotarget. 2014; 5:7051-7064. doi:10.18632/oncotarget.2251.
-
(2014)
Oncotarget
, vol.5
, pp. 7051-7064
-
-
Fofaria, N.M.1
Srivastava, S.K.2
-
62
-
-
84897374481
-
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR
-
Litzenburger UM, Opitz CA, Sahm F, Rauschenbach KJ, Trump S, Winter M, Ott M, Ochs K, Lutz C, Liu XD, Anastasov N, Lehmann I, Hofer T, et al. Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR. Oncotarget. 2014; 5:1038-1051. doi:10.18632/oncotarget.1637.
-
(2014)
Oncotarget
, vol.5
, pp. 1038-1051
-
-
Litzenburger, U.M.1
Opitz, C.A.2
Sahm, F.3
Rauschenbach, K.J.4
Trump, S.5
Winter, M.6
Ott, M.7
Ochs, K.8
Lutz, C.9
Liu, X.D.10
Anastasov, N.11
Lehmann, I.12
Hofer, T.13
-
63
-
-
78149365345
-
STAT3: A Target to Enhance Antitumor Immune Response
-
Lee H, Pal SK, Reckamp K, Figlin RA and Yu H. STAT3: A Target to Enhance Antitumor Immune Response. Curr Top Microbiol. 2011; 344:41-59.
-
(2011)
Curr Top Microbiol
, vol.344
, pp. 41-59
-
-
Lee, H.1
Pal, S.K.2
Reckamp, K.3
Figlin, R.A.4
Yu, H.5
-
64
-
-
79957924781
-
STAT3 Knockdown in B16 Melanoma by siRNA Lipopolyplexes Induces Bystander Immune Response In Vitro and In Vivo
-
Alshamsan A, Hamdy S, Haddadi A, Samuel J, El-Kadi AOS, Uludağ H and Lavasanifar A. STAT3 Knockdown in B16 Melanoma by siRNA Lipopolyplexes Induces Bystander Immune Response In Vitro and In Vivo. Translational oncology. 2011; 4:178-188.
-
(2011)
Translational oncology
, vol.4
, pp. 178-188
-
-
Alshamsan, A.1
Hamdy, S.2
Haddadi, A.3
Samuel, J.4
El-Kadi, A.O.S.5
Uludağ, H.6
Lavasanifar, A.7
-
65
-
-
77957744000
-
STAT3 silencing in dendritic cells by siRNA polyplexes encapsulated in PLGA nanoparticles for the modulation of anticancer immune response
-
Alshamsan A, Haddadi A, Hamdy S, Samuel J, El-Kadi AOS, Uludağ H and Lavasanifar A. STAT3 silencing in dendritic cells by siRNA polyplexes encapsulated in PLGA nanoparticles for the modulation of anticancer immune response. Molecular Pharmaceutics. 2010; 7:1643-1654.
-
(2010)
Molecular Pharmaceutics
, vol.7
, pp. 1643-1654
-
-
Alshamsan, A.1
Haddadi, A.2
Hamdy, S.3
Samuel, J.4
El-Kadi, A.O.S.5
Uludağ, H.6
Lavasanifar, A.7
-
66
-
-
77950563690
-
Development of a poly(D,L-lactic-co-glycolic acid) nanoparticle formulation of STAT3 inhibitor JSI-124: Implication for cancer immunotherapy
-
Molavi O, Mahmud A, Hamdy S, Hung RW, Lai R, Samuel J and Lavasanifar A. Development of a poly(D,L-lactic-co-glycolic acid) nanoparticle formulation of STAT3 inhibitor JSI-124: Implication for cancer immunotherapy. Molecular Pharmaceutics. 2010; 7:364-374.
-
(2010)
Molecular Pharmaceutics
, vol.7
, pp. 364-374
-
-
Molavi, O.1
Mahmud, A.2
Hamdy, S.3
Hung, R.W.4
Lai, R.5
Samuel, J.6
Lavasanifar, A.7
-
67
-
-
80053161466
-
In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles
-
Jewell CM, Lopez SCB and Irvine DJ. In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles. P Natl Acad Sci USA. 2011; 108:15745-15750.
-
(2011)
P Natl Acad Sci USA
, vol.108
, pp. 15745-15750
-
-
Jewell, C.M.1
Lopez, S.C.B.2
Irvine, D.J.3
-
69
-
-
84912120595
-
STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
-
Woo SR, Fuertes MB, Corrales L, Spranger S, Furdyna MJ, Leung MYK, Duggan R, Wang Y, Barber GN, Fitzgerald KA, Alegre ML and Gajewski TF. STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors. Immunity. 2014; 41:830-842.
-
(2014)
Immunity
, vol.41
, pp. 830-842
-
-
Woo, S.R.1
Fuertes, M.B.2
Corrales, L.3
Spranger, S.4
Furdyna, M.J.5
Leung, M.Y.K.6
Duggan, R.7
Wang, Y.8
Barber, G.N.9
Fitzgerald, K.A.10
Alegre, M.L.11
Gajewski, T.F.12
-
70
-
-
79952173864
-
Programming the magnitude and persistence of antibody responses with innate immunity
-
Kasturi SP, Skountzou I, Albrecht RA, Koutsonanos D, Hua T, Nakaya HI, Ravindran R, Stewart S, Alam M, Kwissa M, Villinger F, Murthy N, Steel J, Jacob J, Hogan RJ, Garcia-Sastre A, et al. Programming the magnitude and persistence of antibody responses with innate immunity. Nature. 2011; 470:543-U136.
-
(2011)
Nature
, vol.470
, pp. U136-U543
-
-
Kasturi, S.P.1
Skountzou, I.2
Albrecht, R.A.3
Koutsonanos, D.4
Hua, T.5
Nakaya, H.I.6
Ravindran, R.7
Stewart, S.8
Alam, M.9
Kwissa, M.10
Villinger, F.11
Murthy, N.12
Steel, J.13
Jacob, J.14
Hogan, R.J.15
Garcia-Sastre, A.16
-
71
-
-
84928917822
-
Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma
-
Schadendorf D, Hodi FS, Robert C, Weber JS, Margolin K, Hamid O, Patt D, Chen TT, Berman DM and Wolchok JD. Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma. J Clin Oncol. 2015; 33:1889-U1848.
-
(2015)
J Clin Oncol
, vol.33
, pp. U1848-U1889
-
-
Schadendorf, D.1
Hodi, F.S.2
Robert, C.3
Weber, J.S.4
Margolin, K.5
Hamid, O.6
Patt, D.7
Chen, T.T.8
Berman, D.M.9
Wolchok, J.D.10
-
72
-
-
79959949897
-
Vaccine therapy with sipuleucel-T (Provenge) for prostate cancer
-
Thara E, Dorff TB, Pinski JK and Quinn DI. Vaccine therapy with sipuleucel-T (Provenge) for prostate cancer. Maturitas. 2011; 69:296-303.
-
(2011)
Maturitas
, vol.69
, pp. 296-303
-
-
Thara, E.1
Dorff, T.B.2
Pinski, J.K.3
Quinn, D.I.4
-
73
-
-
33746012881
-
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
Small EJ, Schellhammer PF, Higano CS, Redfern CH, Nemunaitis JJ, Valone FH, Verjee SS, Jones LA and Hershberg RM. Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol. 2006; 24:3089-3094.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3089-3094
-
-
Small, E.J.1
Schellhammer, P.F.2
Higano, C.S.3
Redfern, C.H.4
Nemunaitis, J.J.5
Valone, F.H.6
Verjee, S.S.7
Jones, L.A.8
Hershberg, R.M.9
-
74
-
-
84930418694
-
Targeted treatment of metastatic castration-resistant prostate cancer with sipuleucel-T immunotherapy
-
Mulders PF, De Santis M, Powles T and Fizazi K. Targeted treatment of metastatic castration-resistant prostate cancer with sipuleucel-T immunotherapy. Cancer Immunol Immun. 2015; 64:655-663.
-
(2015)
Cancer Immunol Immun
, vol.64
, pp. 655-663
-
-
Mulders, P.F.1
De Santis, M.2
Powles, T.3
Fizazi, K.4
-
75
-
-
84858780815
-
Cancer immunotherapy via dendritic cells
-
Palucka K and Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer. 2012; 12:265-277.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 265-277
-
-
Palucka, K.1
Banchereau, J.2
-
76
-
-
84939159802
-
Injectable cryogel-based whole-cell cancer vaccines
-
Bencherif SA, Warren Sands R, Ali OA, Li WA, Lewin SA, Braschler TM, Shih TY, Verbeke CS, Bhatta D, Dranoff G and Mooney DJ. Injectable cryogel-based whole-cell cancer vaccines. Nature communications. 2015; 6:7556.
-
(2015)
Nature communications
, vol.6
, pp. 7556
-
-
Bencherif, S.A.1
Warren Sands, R.2
Ali, O.A.3
Li, W.A.4
Lewin, S.A.5
Braschler, T.M.6
Shih, T.Y.7
Verbeke, C.S.8
Bhatta, D.9
Dranoff, G.10
Mooney, D.J.11
-
77
-
-
84896411194
-
Relationship of vaccine efficacy to the kinetics of DC and T-cell responses induced by PLG-based cancer vaccines
-
Ali OA, Doherty E, Mooney DJ and Emerich D. Relationship of vaccine efficacy to the kinetics of DC and T-cell responses induced by PLG-based cancer vaccines. Biomatter. 2011; 1:66-75.
-
(2011)
Biomatter
, vol.1
, pp. 66-75
-
-
Ali, O.A.1
Doherty, E.2
Mooney, D.J.3
Emerich, D.4
-
78
-
-
58949100114
-
Infection-mimicking materials to program dendritic cells in situ
-
Ali OA, Huebsch N, Cao L, Dranoff G and Mooney DJ. Infection-mimicking materials to program dendritic cells in situ. Nature materials. 2009; 8:151-158.
-
(2009)
Nature materials
, vol.8
, pp. 151-158
-
-
Ali, O.A.1
Huebsch, N.2
Cao, L.3
Dranoff, G.4
Mooney, D.J.5
-
79
-
-
84884904183
-
Inflammatory cytokines presented from polymer matrices differentially generate and activate DCs
-
Ali OA, Tayalia P, Shvartsman D, Lewin S and Mooney DJ. Inflammatory cytokines presented from polymer matrices differentially generate and activate DCs. Advanced functional materials. 2013; 23:4621-4628.
-
(2013)
Advanced functional materials
, vol.23
, pp. 4621-4628
-
-
Ali, O.A.1
Tayalia, P.2
Shvartsman, D.3
Lewin, S.4
Mooney, D.J.5
-
80
-
-
84896523011
-
Identification of immune factors regulating antitumor immunity using polymeric vaccines with multiple adjuvants
-
Ali OA, Verbeke C, Johnson C, Sands RW, Lewin SA, White D, Doherty E, Dranoff G and Mooney DJ. Identification of immune factors regulating antitumor immunity using polymeric vaccines with multiple adjuvants. Cancer Res. 2014; 74:1670-1681.
-
(2014)
Cancer Res
, vol.74
, pp. 1670-1681
-
-
Ali, O.A.1
Verbeke, C.2
Johnson, C.3
Sands, R.W.4
Lewin, S.A.5
White, D.6
Doherty, E.7
Dranoff, G.8
Mooney, D.J.9
-
81
-
-
84873182985
-
Characterizing the antitumor response in mice treated with antigen-loaded polyanhydride microparticles
-
Joshi VB, Geary SM, Carrillo-Conde BR, Narasimhan B and Salem AK. Characterizing the antitumor response in mice treated with antigen-loaded polyanhydride microparticles. Acta biomaterialia. 2013; 9:5583-5589.
-
(2013)
Acta biomaterialia
, vol.9
, pp. 5583-5589
-
-
Joshi, V.B.1
Geary, S.M.2
Carrillo-Conde, B.R.3
Narasimhan, B.4
Salem, A.K.5
-
83
-
-
84863121431
-
Trp2 peptide vaccine adjuvanted with (R)-DOTAP inhibits tumor growth in an advanced melanoma model
-
Vasievich EA, Ramishetti S, Zhang Y and Huang L. Trp2 peptide vaccine adjuvanted with (R)-DOTAP inhibits tumor growth in an advanced melanoma model. Mol Pharm. 2012; 9:261-268.
-
(2012)
Mol Pharm
, vol.9
, pp. 261-268
-
-
Vasievich, E.A.1
Ramishetti, S.2
Zhang, Y.3
Huang, L.4
-
84
-
-
84864133449
-
Self-assembled peptide amphiphile micelles containing a cytotoxic T-cell epitope promote a protective immune response in vivo
-
Black M, Trent A, Kostenko Y, Lee JS, Olive C and Tirrell M. Self-assembled peptide amphiphile micelles containing a cytotoxic T-cell epitope promote a protective immune response in vivo. Adv Mater. 2012; 24:3845-3849.
-
(2012)
Adv Mater
, vol.24
, pp. 3845-3849
-
-
Black, M.1
Trent, A.2
Kostenko, Y.3
Lee, J.S.4
Olive, C.5
Tirrell, M.6
-
85
-
-
84928540742
-
Enhanced anti-tumor immune responses and delay of tumor development in human epidermal growth factor receptor 2 mice immunized with an immunostimulatory peptide in poly(D,L-lactic-co-glycolic) acid nanoparticles
-
Campbell DF, Saenz R, Bharati IS, Seible D, Zhang L, Esener S, Messmer B, Larsson M and Messmer D. Enhanced anti-tumor immune responses and delay of tumor development in human epidermal growth factor receptor 2 mice immunized with an immunostimulatory peptide in poly(D,L-lactic-co-glycolic) acid nanoparticles. Breast cancer research : BCR. 2015; 17:48.
-
(2015)
Breast cancer research : BCR
, vol.17
, pp. 48
-
-
Campbell, D.F.1
Saenz, R.2
Bharati, I.S.3
Seible, D.4
Zhang, L.5
Esener, S.6
Messmer, B.7
Larsson, M.8
Messmer, D.9
-
86
-
-
84923878415
-
The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine
-
Julier Z, Martino MM, de Titta A, Jeanbart L and Hubbell JA. The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine. Scientific reports. 2015; 5:8569.
-
(2015)
Scientific reports
, vol.5
, pp. 8569
-
-
Julier, Z.1
Martino, M.M.2
de Titta, A.3
Jeanbart, L.4
Hubbell, J.A.5
-
87
-
-
84921512451
-
Polyacrylate-based delivery system for self-adjuvanting anticancer peptide vaccine
-
Liu TY, Hussein WM, Giddam AK, Jia Z, Reiman JM, Zaman M, McMillan NA, Good MF, Monteiro MJ, Toth I and Skwarczynski M. Polyacrylate-based delivery system for self-adjuvanting anticancer peptide vaccine. Journal of medicinal chemistry. 2015; 58:888-896.
-
(2015)
Journal of medicinal chemistry
, vol.58
, pp. 888-896
-
-
Liu, T.Y.1
Hussein, W.M.2
Giddam, A.K.3
Jia, Z.4
Reiman, J.M.5
Zaman, M.6
McMillan, N.A.7
Good, M.F.8
Monteiro, M.J.9
Toth, I.10
Skwarczynski, M.11
-
88
-
-
84881570194
-
Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer
-
Liu TY, Hussein WM, Jia Z, Ziora ZM, McMillan NA, Monteiro MJ, Toth I and Skwarczynski M. Self-adjuvanting polymer-peptide conjugates as therapeutic vaccine candidates against cervical cancer. Biomacromolecules. 2013; 14:2798-2806.
-
(2013)
Biomacromolecules
, vol.14
, pp. 2798-2806
-
-
Liu, T.Y.1
Hussein, W.M.2
Jia, Z.3
Ziora, Z.M.4
McMillan, N.A.5
Monteiro, M.J.6
Toth, I.7
Skwarczynski, M.8
-
89
-
-
84902116894
-
Whole blood cells loaded with messenger RNA as an anti-tumor vaccine
-
Phua KK, Boczkowski D, Dannull J, Pruitt S, Leong KW and Nair SK. Whole blood cells loaded with messenger RNA as an anti-tumor vaccine. Advanced healthcare materials. 2014; 3:837-842.
-
(2014)
Advanced healthcare materials
, vol.3
, pp. 837-842
-
-
Phua, K.K.1
Boczkowski, D.2
Dannull, J.3
Pruitt, S.4
Leong, K.W.5
Nair, S.K.6
-
90
-
-
84907980704
-
In situ modulation of dendritic cells by injectable thermosensitive hydrogels for cancer vaccines in mice
-
Liu Y, Xiao L, Joo KI, Hu B, Fang J and Wang P. In situ modulation of dendritic cells by injectable thermosensitive hydrogels for cancer vaccines in mice. Biomacromolecules. 2014; 15:3836-3845.
-
(2014)
Biomacromolecules
, vol.15
, pp. 3836-3845
-
-
Liu, Y.1
Xiao, L.2
Joo, K.I.3
Hu, B.4
Fang, J.5
Wang, P.6
-
91
-
-
85027432090
-
Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
-
Phua KKL, Staats HF, Nair SK and Leong KW. Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity. Journal of Controlled Release. 2015; 213:E66-E67.
-
(2015)
Journal of Controlled Release
, vol.213
, pp. E66-E67
-
-
Phua, K.K.L.1
Staats, H.F.2
Nair, S.K.3
Leong, K.W.4
-
92
-
-
84886287251
-
Engineering synthetic vaccines using cues from natural immunity
-
Irvine DJ, Swartz MA and Szeto GL. Engineering synthetic vaccines using cues from natural immunity. Nature materials. 2013; 12:978-990.
-
(2013)
Nature materials
, vol.12
, pp. 978-990
-
-
Irvine, D.J.1
Swartz, M.A.2
Szeto, G.L.3
-
93
-
-
79951899834
-
Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
-
Moon JJ, Suh H, Bershteyn A, Stephan MT, Liu HP, Huang B, Sohail M, Luo S, Um SH, Khant H, Goodwin JT, Ramos J, Chiu W and Irvine DJ. Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nature materials. 2011; 10:243-251.
-
(2011)
Nature materials
, vol.10
, pp. 243-251
-
-
Moon, J.J.1
Suh, H.2
Bershteyn, A.3
Stephan, M.T.4
Liu, H.P.5
Huang, B.6
Sohail, M.7
Luo, S.8
Um, S.H.9
Khant, H.10
Goodwin, J.T.11
Ramos, J.12
Chiu, W.13
Irvine, D.J.14
-
94
-
-
0028910938
-
A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on Mhc Class-I Molecules
-
Kovacsovicsbankowski M and Rock KL. A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on Mhc Class-I Molecules. Science. 1995; 267:243-246.
-
(1995)
Science
, vol.267
, pp. 243-246
-
-
Kovacsovicsbankowski, M.1
Rock, K.L.2
-
95
-
-
33644831362
-
Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles
-
Shen H, Ackerman AL, Cody V, Giodini A, Hinson ER, Cresswell P, Edelson RL, Saltzman WM and Hanlon DJ. Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles. Immunology. 2006; 117:78-88.
-
(2006)
Immunology
, vol.117
, pp. 78-88
-
-
Shen, H.1
Ackerman, A.L.2
Cody, V.3
Giodini, A.4
Hinson, E.R.5
Cresswell, P.6
Edelson, R.L.7
Saltzman, W.M.8
Hanlon, D.J.9
-
96
-
-
78650231557
-
Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation
-
Hirosue S, Kourtis IC, van der Vlies AJ, Hubbell JA and Swartz MA. Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation. Vaccine. 2010; 28:7897-7906.
-
(2010)
Vaccine
, vol.28
, pp. 7897-7906
-
-
Hirosue, S.1
Kourtis, I.C.2
van der Vlies, A.J.3
Hubbell, J.A.4
Swartz, M.A.5
-
97
-
-
84862850542
-
Dendritic cell activation and T cell priming with adjuvant-and antigen-loaded oxidation-sensitive polymersomes
-
Scott EA, Stano A, Gillard M, Maio-Liu AC, Swartz MA and Hubbell JA. Dendritic cell activation and T cell priming with adjuvant-and antigen-loaded oxidation-sensitive polymersomes. Biomaterials. 2012; 33:6211-6219.
-
(2012)
Biomaterials
, vol.33
, pp. 6211-6219
-
-
Scott, E.A.1
Stano, A.2
Gillard, M.3
Maio-Liu, A.C.4
Swartz, M.A.5
Hubbell, J.A.6
-
98
-
-
84906950999
-
Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8(+) T cell responses
-
Keller S, Wilson JT, Patilea GI, Kern HB, Convertine AJ and Stayton PS. Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8(+) T cell responses. Journal of Controlled Release. 2014; 191:24-33.
-
(2014)
Journal of Controlled Release
, vol.191
, pp. 24-33
-
-
Keller, S.1
Wilson, J.T.2
Patilea, G.I.3
Kern, H.B.4
Convertine, A.J.5
Stayton, P.S.6
-
99
-
-
84940000854
-
Enhancement of MHC-I Antigen Presentation via Architectural Control of pH-Responsive, Endosomolytic Polymer Nanoparticles
-
Wilson JT, Postma A, Keller S, Convertine AJ, Moad G, Rizzardo E, Meagher L, Chiefari J and Stayton PS. Enhancement of MHC-I Antigen Presentation via Architectural Control of pH-Responsive, Endosomolytic Polymer Nanoparticles. Aaps J. 2015; 17:358-369.
-
(2015)
Aaps J
, vol.17
, pp. 358-369
-
-
Wilson, J.T.1
Postma, A.2
Keller, S.3
Convertine, A.J.4
Moad, G.5
Rizzardo, E.6
Meagher, L.7
Chiefari, J.8
Stayton, P.S.9
-
100
-
-
78650370883
-
Intracellular Delivery of a Protein Antigen with an Endosomal-Releasing Polymer Enhances CD8 T-Cell Production and Prophylactic Vaccine Efficacy
-
Foster S, Duvall CL, Crownover EF, Hoffman AS and Stayton PS. Intracellular Delivery of a Protein Antigen with an Endosomal-Releasing Polymer Enhances CD8 T-Cell Production and Prophylactic Vaccine Efficacy. Bioconjugate Chem. 2010; 21:2205-2212.
-
(2010)
Bioconjugate Chem
, vol.21
, pp. 2205-2212
-
-
Foster, S.1
Duvall, C.L.2
Crownover, E.F.3
Hoffman, A.S.4
Stayton, P.S.5
-
101
-
-
84878276759
-
pH-Responsive Nanoparticle Vaccines for Dual-Delivery of Antigens and Immunostimulatory Oligonucleotides
-
Wilson JT, Keller S, Manganiello MJ, Cheng C, Lee CC, Opara C, Convertine A and Stayton PS. pH-Responsive Nanoparticle Vaccines for Dual-Delivery of Antigens and Immunostimulatory Oligonucleotides. Acs Nano. 2013; 7:3912-3925.
-
(2013)
Acs Nano
, vol.7
, pp. 3912-3925
-
-
Wilson, J.T.1
Keller, S.2
Manganiello, M.J.3
Cheng, C.4
Lee, C.C.5
Opara, C.6
Convertine, A.7
Stayton, P.S.8
-
102
-
-
84919667582
-
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
-
Rosalia RA, Cruz LJ, van Duikeren S, Tromp AT, Silva AL, Jiskoot W, de Gruijl T, Lowik C, Oostendorp J, van der Burg SH and Ossendorp F. CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses. Biomaterials. 2015; 40:88-97.
-
(2015)
Biomaterials
, vol.40
, pp. 88-97
-
-
Rosalia, R.A.1
Cruz, L.J.2
van Duikeren, S.3
Tromp, A.T.4
Silva, A.L.5
Jiskoot, W.6
de Gruijl, T.7
Lowik, C.8
Oostendorp, J.9
van der Burg, S.H.10
Ossendorp, F.11
-
103
-
-
84920270658
-
Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses
-
Zeng Q, Jiang H, Wang T, Zhang Z, Gong T and Sun X. Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses. Journal of controlled release : official journal of the Controlled Release Society. 2015; 200:1-12.
-
(2015)
Journal of controlled release : official journal of the Controlled Release Society
, vol.200
, pp. 1-12
-
-
Zeng, Q.1
Jiang, H.2
Wang, T.3
Zhang, Z.4
Gong, T.5
Sun, X.6
-
104
-
-
2942627626
-
Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses
-
Seong SY and Matzinger P. Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat Rev Immunol. 2004; 4:469-478.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 469-478
-
-
Seong, S.Y.1
Matzinger, P.2
-
105
-
-
84891018543
-
Nanoscale artificial antigen presenting cells for T cell immunotherapy
-
Perica K, De Leon Medero A, Durai M, Chiu YL, Bieler JG, Sibener L, Niemoller M, Assenmacher M, Richter A, Edidin M, Oelke M and Schneck J. Nanoscale artificial antigen presenting cells for T cell immunotherapy. Nanomedicine : nanotechnology, biology, and medicine. 2014; 10:119-129.
-
(2014)
Nanomedicine : nanotechnology, biology, and medicine
, vol.10
, pp. 119-129
-
-
Perica, K.1
De Leon Medero, A.2
Durai, M.3
Chiu, Y.L.4
Bieler, J.G.5
Sibener, L.6
Niemoller, M.7
Assenmacher, M.8
Richter, A.9
Edidin, M.10
Oelke, M.11
Schneck, J.12
-
106
-
-
73649090450
-
In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer
-
Ugel S, Zoso A, De Santo C, Li Y, Marigo I, Zanovello P, Scarselli E, Cipriani B, Oelke M, Schneck JP and Bronte V. In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer. Cancer Res. 2009; 69:9376-9384.
-
(2009)
Cancer Res
, vol.69
, pp. 9376-9384
-
-
Ugel, S.1
Zoso, A.2
De Santo, C.3
Li, Y.4
Marigo, I.5
Zanovello, P.6
Scarselli, E.7
Cipriani, B.8
Oelke, M.9
Schneck, J.P.10
Bronte, V.11
-
107
-
-
48149104076
-
Whole-cell cancer vaccination: from autologous to allogeneic tumor-and dendritic cell-based vaccines
-
de Gruijl TD, van den Eertwegh AJM, Pinedo HM and Scheper RJ. Whole-cell cancer vaccination: from autologous to allogeneic tumor-and dendritic cell-based vaccines. Cancer Immunol Immun. 2008; 57:1569-1577.
-
(2008)
Cancer Immunol Immun
, vol.57
, pp. 1569-1577
-
-
de Gruijl, T.D.1
van den Eertwegh, A.J.M.2
Pinedo, H.M.3
Scheper, R.J.4
-
108
-
-
0027538181
-
Vaccination with Irradiated Tumor-Cells Engineered to Secrete Murine Granulocyte-Macrophage Colony-Stimulating Factor Stimulates Potent, Specific, and Long-Lasting Antitumor Immunity
-
Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, Jackson V, Hamada H, Pardoll D and Mulligan RC. Vaccination with Irradiated Tumor-Cells Engineered to Secrete Murine Granulocyte-Macrophage Colony-Stimulating Factor Stimulates Potent, Specific, and Long-Lasting Antitumor Immunity. P Natl Acad Sci USA. 1993; 90:3539-3543.
-
(1993)
P Natl Acad Sci USA
, vol.90
, pp. 3539-3543
-
-
Dranoff, G.1
Jaffee, E.2
Lazenby, A.3
Golumbek, P.4
Levitsky, H.5
Brose, K.6
Jackson, V.7
Hamada, H.8
Pardoll, D.9
Mulligan, R.C.10
-
109
-
-
77953720628
-
In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice
-
Ali OA, Emerich D, Dranoff G and Mooney DJ. In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice. Sci Transl Med. 2009; 1.
-
(2009)
Sci Transl Med
, pp. 1
-
-
Ali, O.A.1
Emerich, D.2
Dranoff, G.3
Mooney, D.J.4
-
110
-
-
84870309160
-
Injectable preformed scaffolds with shape-memory properties
-
Bencherif SA, Sands RW, Bhatta D, Arany P, Verbeke CS, Edwards DA and Mooney DJ. Injectable preformed scaffolds with shape-memory properties. Proc Natl Acad Sci U S A. 2012; 109:19590-19595.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 19590-19595
-
-
Bencherif, S.A.1
Sands, R.W.2
Bhatta, D.3
Arany, P.4
Verbeke, C.S.5
Edwards, D.A.6
Mooney, D.J.7
-
111
-
-
66349097221
-
Promising novel immunotherapies and combinations for prostate cancer
-
Arlen PM, Mohebtash M, Madan RA and Gulley JL. Promising novel immunotherapies and combinations for prostate cancer. Future Oncol. 2009; 5:187-196.
-
(2009)
Future Oncol
, vol.5
, pp. 187-196
-
-
Arlen, P.M.1
Mohebtash, M.2
Madan, R.A.3
Gulley, J.L.4
-
115
-
-
34848857434
-
Transforming growth factor-beta and the immune response: Implications for anticancer therapy
-
Wrzesinski SH, Wan YSY and Flavell RA. Transforming growth factor-beta and the immune response: Implications for anticancer therapy. Clin Cancer Res. 2007; 13:5262-5270.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5262-5270
-
-
Wrzesinski, S.H.1
Wan, Y.S.Y.2
Flavell, R.A.3
-
116
-
-
84944045501
-
Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner
-
Holmgaard RB, Zamarin D, Li YY, Gasmi B, Munn DH, Allison JP, Merghoub T and Wolchok JD. Tumor-Expressed IDO Recruits and Activates MDSCs in a Treg-Dependent Manner. Cell Rep. 2015; 13:412-424.
-
(2015)
Cell Rep
, vol.13
, pp. 412-424
-
-
Holmgaard, R.B.1
Zamarin, D.2
Li, Y.Y.3
Gasmi, B.4
Munn, D.H.5
Allison, J.P.6
Merghoub, T.7
Wolchok, J.D.8
-
117
-
-
84899457547
-
Nanoparticle-Delivered Transforming Growth Factor-beta siRNA Enhances Vaccination against Advanced Melanoma by Modifying Tumor Microenvironment
-
Xu ZH, Wang YH, Zhang L and Huang L. Nanoparticle-Delivered Transforming Growth Factor-beta siRNA Enhances Vaccination against Advanced Melanoma by Modifying Tumor Microenvironment. Acs Nano. 2014; 8:3636-3645.
-
(2014)
Acs Nano
, vol.8
, pp. 3636-3645
-
-
Xu, Z.H.1
Wang, Y.H.2
Zhang, L.3
Huang, L.4
-
118
-
-
84936147067
-
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P, Ferrucci PF, Hill A, Wagstaff J, Carlino MS, Haanen JB, Maio M, et al. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. The New England journal of medicine. 2015; 373:23-34.
-
(2015)
The New England journal of medicine
, vol.373
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
Grob, J.J.4
Cowey, C.L.5
Lao, C.D.6
Schadendorf, D.7
Dummer, R.8
Smylie, M.9
Rutkowski, P.10
Ferrucci, P.F.11
Hill, A.12
Wagstaff, J.13
Carlino, M.S.14
Haanen, J.B.15
Maio, M.16
-
119
-
-
84899928563
-
A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7
-
Fox CB, Sivananthan SJ, Duthie MS, Vergara J, Guderian JA, Moon E, Coblentz D, Reed SG and Carter D. A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7. Journal of nanobiotechnology. 2014; 12:17-17.
-
(2014)
Journal of nanobiotechnology
, vol.12
, pp. 17-17
-
-
Fox, C.B.1
Sivananthan, S.J.2
Duthie, M.S.3
Vergara, J.4
Guderian, J.A.5
Moon, E.6
Coblentz, D.7
Reed, S.G.8
Carter, D.9
-
120
-
-
84868094428
-
+ T-cell responses in melanoma patients
-
+ T-cell responses in melanoma patients. European journal of immunology. 2012; 42:3049-3061.
-
(2012)
European journal of immunology
, vol.42
, pp. 3049-3061
-
-
Goldinger, S.M.1
Dummer, R.2
Baumgaertner, P.3
Mihic-Probst, D.4
Schwarz, K.5
Hammann-Haenni, A.6
Willers, J.7
Geldhof, C.8
Prior, J.O.9
Kündig, T.M.10
Michielin, O.11
Bachmann, M.F.12
Speiser, D.E.13
-
121
-
-
84886749794
-
Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response
-
Thomas SN, Vokali E, Lund AW, Hubbell JA and Swartz MA. Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response. Biomaterials. 2014; 35:814-824.
-
(2014)
Biomaterials
, vol.35
, pp. 814-824
-
-
Thomas, S.N.1
Vokali, E.2
Lund, A.W.3
Hubbell, J.A.4
Swartz, M.A.5
-
122
-
-
33846207958
-
MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists
-
Bagchi A, Herrup EA, Warren HS, Trigilio J, Shin HS, Valentine C and Hellman J. MyD88-dependent and MyD88-independent pathways in synergy, priming, and tolerance between TLR agonists. J Immunol. 2007; 178:1164-1171.
-
(2007)
J Immunol
, vol.178
, pp. 1164-1171
-
-
Bagchi, A.1
Herrup, E.A.2
Warren, H.S.3
Trigilio, J.4
Shin, H.S.5
Valentine, C.6
Hellman, J.7
-
123
-
-
76649093262
-
Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice
-
Zhu Q, Egelston C, Gagnon S, Sui Y, Belyakov IM, Klinman DM and Berzofsky JA. Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice. The Journal of clinical investigation. 2010; 120:607-616.
-
(2010)
The Journal of clinical investigation
, vol.120
, pp. 607-616
-
-
Zhu, Q.1
Egelston, C.2
Gagnon, S.3
Sui, Y.4
Belyakov, I.M.5
Klinman, D.M.6
Berzofsky, J.A.7
-
124
-
-
84875027497
-
Blueprints of Signaling Interactions between Pattern Recognition Receptors: Implications for the Design of Vaccine Adjuvants
-
Timmermans K, Plantinga TS, Kox M, Vaneker M, Scheffer GJ, Adema GJ, Joosten LAB and Netea MG. Blueprints of Signaling Interactions between Pattern Recognition Receptors: Implications for the Design of Vaccine Adjuvants. Clin Vaccine Immunol. 2013; 20:427-432.
-
(2013)
Clin Vaccine Immunol
, vol.20
, pp. 427-432
-
-
Timmermans, K.1
Plantinga, T.S.2
Kox, M.3
Vaneker, M.4
Scheffer, G.J.5
Adema, G.J.6
Joosten, L.A.B.7
Netea, M.G.8
-
125
-
-
84884609482
-
Covalent modification of cell surfaces with TLR agonists improves & directs immune stimulation
-
Tom JK, Mancini RJ and Esser-Kahn AP. Covalent modification of cell surfaces with TLR agonists improves & directs immune stimulation. Chem Commun. 2013; 49:9618-9620.
-
(2013)
Chem Commun
, vol.49
, pp. 9618-9620
-
-
Tom, J.K.1
Mancini, R.J.2
Esser-Kahn, A.P.3
-
126
-
-
84929379430
-
Cancer immunotherapy. Neo approaches to cancer vaccines
-
Delamarre L, Mellman I and Yadav M. Cancer immunotherapy. Neo approaches to cancer vaccines. Science. 2015; 348:760-761.
-
(2015)
Science
, vol.348
, pp. 760-761
-
-
Delamarre, L.1
Mellman, I.2
Yadav, M.3
-
127
-
-
84898548289
-
Targeted immunomodulation using antigen-conjugated nanoparticles
-
McCarthy DP, Hunter ZN, Chackerian B, Shea LD and Miller SD. Targeted immunomodulation using antigen-conjugated nanoparticles. Wires Nanomed Nanobi. 2014; 6:298-315.
-
(2014)
Wires Nanomed Nanobi
, vol.6
, pp. 298-315
-
-
McCarthy, D.P.1
Hunter, Z.N.2
Chackerian, B.3
Shea, L.D.4
Miller, S.D.5
-
128
-
-
84889571890
-
Pathogen-like particles: biomimetic vaccine carriers engineered at the nanoscale
-
Rosenthal JA, Chen LX, Baker JL, Putnam D and DeLisa MP. Pathogen-like particles: biomimetic vaccine carriers engineered at the nanoscale. Curr Opin Biotech. 2014; 28:51-58.
-
(2014)
Curr Opin Biotech
, vol.28
, pp. 51-58
-
-
Rosenthal, J.A.1
Chen, L.X.2
Baker, J.L.3
Putnam, D.4
DeLisa, M.P.5
-
129
-
-
77958051699
-
Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients
-
Speiser DE, Schwarz K, Baumgaertner P, Manolova V, Devevre E, Sterry W, Walden P, Zippelius A, Conzett KB, Senti G, Voelter V, Cerottini JP, Guggisberg D, Willers J, Geldhof C, Romero P, et al. Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients. J Immunother. 2010; 33:848-858.
-
(2010)
J Immunother
, vol.33
, pp. 848-858
-
-
Speiser, D.E.1
Schwarz, K.2
Baumgaertner, P.3
Manolova, V.4
Devevre, E.5
Sterry, W.6
Walden, P.7
Zippelius, A.8
Conzett, K.B.9
Senti, G.10
Voelter, V.11
Cerottini, J.P.12
Guggisberg, D.13
Willers, J.14
Geldhof, C.15
Romero, P.16
-
130
-
-
84922101073
-
Biodegradable Microparticles Loaded with Doxorubicin and CpG ODN for In Situ Immunization Against Cancer
-
Makkouk A, Joshi VB, Wongrakpanich A, Lemke CD, Gross BP, Salem AK and Weiner GJ. Biodegradable Microparticles Loaded with Doxorubicin and CpG ODN for In Situ Immunization Against Cancer. The AAPS Journal. 2014; 17:184-193.
-
(2014)
The AAPS Journal
, vol.17
, pp. 184-193
-
-
Makkouk, A.1
Joshi, V.B.2
Wongrakpanich, A.3
Lemke, C.D.4
Gross, B.P.5
Salem, A.K.6
Weiner, G.J.7
-
131
-
-
84874941640
-
Nanoparticle mediated co-delivery of paclitaxel and a TLR-4 agonist results in tumor regression and enhanced immune response in the tumor microenvironment of a mouse model
-
Roy A, Singh MS, Upadhyay P and Bhaskar S. Nanoparticle mediated co-delivery of paclitaxel and a TLR-4 agonist results in tumor regression and enhanced immune response in the tumor microenvironment of a mouse model. International Journal of Pharmaceutics. 2013; 445:171-180.
-
(2013)
International Journal of Pharmaceutics
, vol.445
, pp. 171-180
-
-
Roy, A.1
Singh, M.S.2
Upadhyay, P.3
Bhaskar, S.4
-
132
-
-
84894562122
-
Thermal ablation of tumours: biological mechanisms and advances in therapy
-
Chu KF and Dupuy DE. Thermal ablation of tumours: biological mechanisms and advances in therapy. Nat Rev Cancer. 2014; 14:199-208.
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 199-208
-
-
Chu, K.F.1
Dupuy, D.E.2
-
133
-
-
84912525332
-
The impact of radiation therapy on the antitumor immunity: Local effects and systemic consequences
-
Lumniczky K and Safrany G. The impact of radiation therapy on the antitumor immunity: Local effects and systemic consequences. Cancer Lett. 2015; 356:114-125.
-
(2015)
Cancer Lett
, vol.356
, pp. 114-125
-
-
Lumniczky, K.1
Safrany, G.2
-
134
-
-
67649359533
-
Systemic effects of local radiotherapy
-
Formenti SC and Demaria S. Systemic effects of local radiotherapy. Lancet Oncol. 2009; 10:718-726.
-
(2009)
Lancet Oncol
, vol.10
, pp. 718-726
-
-
Formenti, S.C.1
Demaria, S.2
-
135
-
-
84871731761
-
Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer
-
Marrache S, Choi JH, Tundup S, Zaver D, Harn Da and Dhar S. Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer. Integrative Biology. 2012:215-223.
-
(2012)
Integrative Biology
, pp. 215-223
-
-
Marrache, S.1
Choi, J.H.2
Tundup, S.3
Zaver, D.4
Da, H.5
Dhar, S.6
-
136
-
-
84876561994
-
Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice
-
Kourtis IC, Hirosue S, de Titta A, Kontos S, Stegmann T, Hubbell JA and Swartz MA. Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice. PloS one. 2013; 8:e61646.
-
(2013)
PloS one
, vol.8
-
-
Kourtis, I.C.1
Hirosue, S.2
de Titta, A.3
Kontos, S.4
Stegmann, T.5
Hubbell, J.A.6
Swartz, M.A.7
-
137
-
-
84941043701
-
In vivo capture and label-free detection of early metastatic cells
-
Azarin SM, Yi J, Gower RM, Aguado BA, Sullivan ME, Goodman AG, Jiang EJ, Rao SS, Ren Y, Tucker SL, Backman V, Jeruss JS and Shea LD. In vivo capture and label-free detection of early metastatic cells. Nature communications. 2015; 6:8094.
-
(2015)
Nature communications
, vol.6
, pp. 8094
-
-
Azarin, S.M.1
Yi, J.2
Gower, R.M.3
Aguado, B.A.4
Sullivan, M.E.5
Goodman, A.G.6
Jiang, E.J.7
Rao, S.S.8
Ren, Y.9
Tucker, S.L.10
Backman, V.11
Jeruss, J.S.12
Shea, L.D.13
-
138
-
-
84930817695
-
Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells
-
Huang BN, Abraham WD, Zheng YR, Lopez SCB, Luo SS and Irvine DJ. Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells. Sci Transl Med. 2015; 7.
-
(2015)
Sci Transl Med
, pp. 7
-
-
Huang, B.N.1
Abraham, W.D.2
Zheng, Y.R.3
Lopez, S.C.B.4
Luo, S.S.5
Irvine, D.J.6
-
139
-
-
84926170848
-
Ibrutinib enhances the antitumor immune response induced by intratumoral injection of a TLR9 ligand in mouse lymphoma
-
Sagiv-Barfi I, Kohrt HE, Burckhardt L, Czerwinski DK and Levy R. Ibrutinib enhances the antitumor immune response induced by intratumoral injection of a TLR9 ligand in mouse lymphoma. Blood. 2015; 125:2079-2086.
-
(2015)
Blood
, vol.125
, pp. 2079-2086
-
-
Sagiv-Barfi, I.1
Kohrt, H.E.2
Burckhardt, L.3
Czerwinski, D.K.4
Levy, R.5
-
140
-
-
79960632175
-
Membrane anchored immunostimulatory oligonucleotides for in vivo cell modification and localized immunotherapy
-
Liu H, Kwong B and Irvine DJ. Membrane anchored immunostimulatory oligonucleotides for in vivo cell modification and localized immunotherapy. Angewandte Chemie. 2011; 50:7052-7055.
-
(2011)
Angewandte Chemie
, vol.50
, pp. 7052-7055
-
-
Liu, H.1
Kwong, B.2
Irvine, D.J.3
-
141
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993
-
Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, Abrams J, Sznol M, Parkinson D, Hawkins M, Paradise C, Kunkel L and Rosenberg SA. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993. J Clin Oncol. 1999; 17:2105-2116.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
Fisher, R.I.4
Weiss, G.5
Margolin, K.6
Abrams, J.7
Sznol, M.8
Parkinson, D.9
Hawkins, M.10
Paradise, C.11
Kunkel, L.12
Rosenberg, S.A.13
-
142
-
-
53049088033
-
Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines
-
Smith FO, Downey SG, Klapper JA, Yang JC, Sherry RM, Royal RE, Kammula US, Hughes MS, Restifo NP, Levy CL, White DE, Steinberg SM and Rosenberg SA. Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines. Clin Cancer Res. 2008; 14:5610-5618.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5610-5618
-
-
Smith, F.O.1
Downey, S.G.2
Klapper, J.A.3
Yang, J.C.4
Sherry, R.M.5
Royal, R.E.6
Kammula, U.S.7
Hughes, M.S.8
Restifo, N.P.9
Levy, C.L.10
White, D.E.11
Steinberg, S.M.12
Rosenberg, S.A.13
-
143
-
-
84866743713
-
Combination delivery of TGF-beta inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
-
Park J, Wrzesinski SH, Stern E, Look M, Criscione J, Ragheb R, Jay SM, Demento SL, Agawu A, Licona Limon P, Ferrandino AF, Gonzalez D, Habermann A, Flavell RA and Fahmy TM. Combination delivery of TGF-beta inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy. Nature materials. 2012; 11:895-905.
-
(2012)
Nature materials
, vol.11
, pp. 895-905
-
-
Park, J.1
Wrzesinski, S.H.2
Stern, E.3
Look, M.4
Criscione, J.5
Ragheb, R.6
Jay, S.M.7
Demento, S.L.8
Agawu, A.9
Licona Limon, P.10
Ferrandino, A.F.11
Gonzalez, D.12
Habermann, A.13
Flavell, R.A.14
Fahmy, T.M.15
-
144
-
-
84884365015
-
The causes and consequences of genetic heterogeneity in cancer evolution
-
Burrell RA, McGranahan N, Bartek J and Swanton C. The causes and consequences of genetic heterogeneity in cancer evolution. Nature. 2013; 501:338-345.
-
(2013)
Nature
, vol.501
, pp. 338-345
-
-
Burrell, R.A.1
McGranahan, N.2
Bartek, J.3
Swanton, C.4
-
145
-
-
84884377472
-
Tumour heterogeneity and cancer cell plasticity
-
Meacham CE and Morrison SJ. Tumour heterogeneity and cancer cell plasticity. Nature. 2013; 501:328-337.
-
(2013)
Nature
, vol.501
, pp. 328-337
-
-
Meacham, C.E.1
Morrison, S.J.2
-
146
-
-
0036631492
-
Identification of tumour-associated T-CELL epitopes for vaccine development
-
Stevanovic S. Identification of tumour-associated T-CELL epitopes for vaccine development. Nat Rev Cancer. 2002; 2:514-520.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 514-520
-
-
Stevanovic, S.1
-
147
-
-
21044437815
-
Sequential Immune Escape and Shifting of T Cell Responses in a Long-Term Survivor of Melanoma
-
Yamshchikov GV, Mullins DW, Chang CC, Ogino T, Thompson L, Presley J, Galavotti H, Aquila W, Deacon D, Ross W, Patterson JW, Engelhard VH, Ferrone S and Slingluff CL. Sequential Immune Escape and Shifting of T Cell Responses in a Long-Term Survivor of Melanoma. The Journal of Immunology. 2005; 174:6863-6871.
-
(2005)
The Journal of Immunology
, vol.174
, pp. 6863-6871
-
-
Yamshchikov, G.V.1
Mullins, D.W.2
Chang, C.C.3
Ogino, T.4
Thompson, L.5
Presley, J.6
Galavotti, H.7
Aquila, W.8
Deacon, D.9
Ross, W.10
Patterson, J.W.11
Engelhard, V.H.12
Ferrone, S.13
Slingluff, C.L.14
-
148
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher TN and Schreiber RD. Neoantigens in cancer immunotherapy. Science. 2015; 348:69-74.
-
(2015)
Science
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
150
-
-
79953151458
-
Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
-
Schreiber RD, Old LJ and Smyth MJ. Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion. Science. 2011; 331:1565-1570.
-
(2011)
Science
, vol.331
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
151
-
-
84920956731
-
Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
-
Yadav M, Jhunjhunwala S, Phung QT, Lupardus P, Tanguay J, Bumbaca S, Franci C, Cheung TK, Fritsche J, Weinschenk T, Modrusan Z, Mellman I, Lill JR and Delamarre L. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature. 2014; 515:572.
-
(2014)
Nature
, vol.515
, pp. 572
-
-
Yadav, M.1
Jhunjhunwala, S.2
Phung, Q.T.3
Lupardus, P.4
Tanguay, J.5
Bumbaca, S.6
Franci, C.7
Cheung, T.K.8
Fritsche, J.9
Weinschenk, T.10
Modrusan, Z.11
Mellman, I.12
Lill, J.R.13
Delamarre, L.14
-
152
-
-
84920921528
-
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
-
Gubin MM, Zhang XL, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SSK, Korman AJ, Allison JP, et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature. 2014; 515:577.
-
(2014)
Nature
, vol.515
, pp. 577
-
-
Gubin, M.M.1
Zhang, X.L.2
Schuster, H.3
Caron, E.4
Ward, J.P.5
Noguchi, T.6
Ivanova, Y.7
Hundal, J.8
Arthur, C.D.9
Krebber, W.J.10
Mulder, G.E.11
Toebes, M.12
Vesely, M.D.13
Lam, S.S.K.14
Korman, A.J.15
Allison, J.P.16
-
153
-
-
84857725402
-
Exploiting the Mutanome for Tumor Vaccination
-
Castle JC, Kreiter S, Diekmann J, Lower M, Van de Roemer N, de Graaf J, Selmi A, Diken M, Boegel S, Paret C, Koslowski M, Kuhn AN, Britten CM, Huber C, Tuereci O and Sahin U. Exploiting the Mutanome for Tumor Vaccination. Cancer Research. 2012; 72:1081-1091.
-
(2012)
Cancer Research
, vol.72
, pp. 1081-1091
-
-
Castle, J.C.1
Kreiter, S.2
Diekmann, J.3
Lower, M.4
Van de Roemer, N.5
de Graaf, J.6
Selmi, A.7
Diken, M.8
Boegel, S.9
Paret, C.10
Koslowski, M.11
Kuhn, A.N.12
Britten, C.M.13
Huber, C.14
Tuereci, O.15
Sahin, U.16
-
154
-
-
78751681345
-
Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell-based antitumor immunotherapy
-
Prasad S, Cody V, Saucier-Sawyer JK, Saltzman WM, Sasaki CT, Edelson RL, Birchall MA and Hanlon DJ. Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell-based antitumor immunotherapy. Nanomedicine : nanotechnology, biology, and medicine. 2011; 7:1-10.
-
(2011)
Nanomedicine : nanotechnology, biology, and medicine
, vol.7
, pp. 1-10
-
-
Prasad, S.1
Cody, V.2
Saucier-Sawyer, J.K.3
Saltzman, W.M.4
Sasaki, C.T.5
Edelson, R.L.6
Birchall, M.A.7
Hanlon, D.J.8
-
155
-
-
84938807240
-
A Therapeutic Microparticle-Based Tumor Lysate Vaccine Reduces Spontaneous Metastases in Murine Breast Cancer
-
Gross BP, Wongrakpanich A, Francis MB, Salem AK and Norian LA. A Therapeutic Microparticle-Based Tumor Lysate Vaccine Reduces Spontaneous Metastases in Murine Breast Cancer. Aaps J. 2014; 16:1194-1203.
-
(2014)
Aaps J
, vol.16
, pp. 1194-1203
-
-
Gross, B.P.1
Wongrakpanich, A.2
Francis, M.B.3
Salem, A.K.4
Norian, L.A.5
-
156
-
-
84949255545
-
TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma
-
Damo M, Wilson DS, Simeoni E and Hubbell JA. TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma. Scientific reports. 2015; 5:17622.
-
(2015)
Scientific reports
, vol.5
, pp. 17622
-
-
Damo, M.1
Wilson, D.S.2
Simeoni, E.3
Hubbell, J.A.4
-
157
-
-
84900333051
-
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
-
Lohr JG, Adalsteinsson VA, Cibulskis K, Choudhury AD, Rosenberg M, Cruz-Gordillo P, Francis JM, Zhang CZ, Shalek AK, Satija R, Trombetta JJ, Lu D, Tallapragada N, Tahirova N, Kim S, Blumenstiel B, et al. Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nat Biotechnol. 2014; 32:479-U202.
-
(2014)
Nat Biotechnol
, vol.32
, pp. U202-U479
-
-
Lohr, J.G.1
Adalsteinsson, V.A.2
Cibulskis, K.3
Choudhury, A.D.4
Rosenberg, M.5
Cruz-Gordillo, P.6
Francis, J.M.7
Zhang, C.Z.8
Shalek, A.K.9
Satija, R.10
Trombetta, J.J.11
Lu, D.12
Tallapragada, N.13
Tahirova, N.14
Kim, S.15
Blumenstiel, B.16
-
158
-
-
84934437818
-
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
-
Sarioglu AF, Aceto N, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan TK, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, et al. A microfluidic device for label-free, physical capture of circulating tumor cell clusters. Nat Methods. 2015; 12:685.
-
(2015)
Nat Methods
, vol.12
, pp. 685
-
-
Sarioglu, A.F.1
Aceto, N.2
Kojic, N.3
Donaldson, M.C.4
Zeinali, M.5
Hamza, B.6
Engstrom, A.7
Zhu, H.8
Sundaresan, T.K.9
Miyamoto, D.T.10
Luo, X.11
Bardia, A.12
Wittner, B.S.13
Ramaswamy, S.14
Shioda, T.15
Ting, D.T.16
-
159
-
-
84859734250
-
Full Surface Embedding of Gold Clusters on Silicon Nanowires for Efficient Capture and Photothermal Therapy of Circulating Tumor Cells (vol 12, pg 1638, 2012)
-
Park GS, Kwon H, Kwak DW, Park SY, Kim M, Lee JH, Han H, Heo S, Li XS, Lee JH, Kim YH, Lee JG, Yang W, Cho HY, Kim SK and Kim K. Full Surface Embedding of Gold Clusters on Silicon Nanowires for Efficient Capture and Photothermal Therapy of Circulating Tumor Cells (vol 12, pg 1638, 2012). Nano Lett. 2012; 12:2176-2176.
-
(2012)
Nano Lett
, vol.12
, pp. 2176-2176
-
-
Park, G.S.1
Kwon, H.2
Kwak, D.W.3
Park, S.Y.4
Kim, M.5
Lee, J.H.6
Han, H.7
Heo, S.8
Li, X.S.9
Lee, J.H.10
Kim, Y.H.11
Lee, J.G.12
Yang, W.13
Cho, H.Y.14
Kim, S.K.15
Kim, K.16
-
160
-
-
84897500392
-
SpyLigase peptide-peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture
-
Fierer JO, Veggiani G and Howarth M. SpyLigase peptide-peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture. P Natl Acad Sci USA. 2014; 111:E1176-E1181.
-
(2014)
P Natl Acad Sci USA
, vol.111
, pp. E1176-E1181
-
-
Fierer, J.O.1
Veggiani, G.2
Howarth, M.3
-
161
-
-
84928243618
-
Acoustic separation of circulating tumor cells
-
Li P, Mao ZM, Peng ZL, Zhou LL, Chen YC, Huang PH, Truica CI, Drabick JJ, El-Deiry WS, Dao M, Suresh S and Huang TJ. Acoustic separation of circulating tumor cells. P Natl Acad Sci USA. 2015; 112:4970-4975.
-
(2015)
P Natl Acad Sci USA
, vol.112
, pp. 4970-4975
-
-
Li, P.1
Mao, Z.M.2
Peng, Z.L.3
Zhou, L.L.4
Chen, Y.C.5
Huang, P.H.6
Truica, C.I.7
Drabick, J.J.8
El-Deiry, W.S.9
Dao, M.10
Suresh, S.11
Huang, T.J.12
-
162
-
-
84914127560
-
NanoFlares for the detection, isolation, and culture of live tumor cells from human blood
-
Halo TL, McMahon KM, Angeloni NL, Xu YL, Wang W, Chinen AB, Malin D, Strekalova E, Cryns VL, Cheng CH, Mirkin CA and Thaxton CS. NanoFlares for the detection, isolation, and culture of live tumor cells from human blood. P Natl Acad Sci USA. 2014; 111:17104-17109.
-
(2014)
P Natl Acad Sci USA
, vol.111
, pp. 17104-17109
-
-
Halo, T.L.1
McMahon, K.M.2
Angeloni, N.L.3
Xu, Y.L.4
Wang, W.5
Chinen, A.B.6
Malin, D.7
Strekalova, E.8
Cryns, V.L.9
Cheng, C.H.10
Mirkin, C.A.11
Thaxton, C.S.12
|