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Volumn 17, Issue 7, 1999, Pages 2105-2116

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: Analysis of 270 patients treated between 1985 and 1993

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; RECOMBINANT INTERLEUKIN 2;

EID: 0033024863     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.1999.17.7.2105     Document Type: Article
Times cited : (1752)

References (50)
  • 1
    • 0003077969 scopus 로고    scopus 로고
    • Cutaneous melanoma
    • DeVita VT Jr, Hellman S, Rosenberg SA (eds). Philadelphia, PA, Lippincott-Raven
    • Balch CM, Reintgen DS, Kirkwood JM, et al: Cutaneous melanoma, in DeVita VT Jr, Hellman S, Rosenberg SA (eds): Cancer: Principles and Practice of Oncology. Philadelphia, PA, Lippincott-Raven, 1997, pp 1947-1994
    • (1997) Cancer: Principles and Practice of Oncology , pp. 1947-1994
    • Balch, C.M.1    Reintgen, D.S.2    Kirkwood, J.M.3
  • 2
    • 0021077073 scopus 로고
    • A multi-factorial analysis of melanoma: IV. Prognostic factors in 200 melanoma patients with distant metastasis
    • Balch CM, Soong S-J, Murad TM, et al: A multi-factorial analysis of melanoma: IV. Prognostic factors in 200 melanoma patients with distant metastasis. J Clin Oncol 1:126-134, 1983
    • (1983) J Clin Oncol , vol.1 , pp. 126-134
    • Balch, C.M.1    Soong, S.-J.2    Murad, T.M.3
  • 3
    • 0029086370 scopus 로고
    • Prognostic factors in 1,521 melanoma patients with distant metastases
    • Earth A, Wanek LA, Morton DL: Prognostic factors in 1,521 melanoma patients with distant metastases. J Am Coll Surg 181:193-201, 1995
    • (1995) J Am Coll Surg , vol.181 , pp. 193-201
    • Earth, A.1    Wanek, L.A.2    Morton, D.L.3
  • 4
    • 0027312394 scopus 로고
    • Prognostic factors in metastatic melanoma
    • Ryan L, Kramar A, Borden E: Prognostic factors in metastatic melanoma. Cancer 71:2995-3005, 1993
    • (1993) Cancer , vol.71 , pp. 2995-3005
    • Ryan, L.1    Kramar, A.2    Borden, E.3
  • 5
    • 0021325538 scopus 로고
    • Dimethyl triazeno imidazole carboxamide and combination therapy for melanoma: IV. Late results after complete response to chemotherapy (central oncology group protocols 7130, 7131, and 7131A)
    • Hill GJ 2d, Krementz ET, Hill HZ: Dimethyl triazeno imidazole carboxamide and combination therapy for melanoma: IV. Late results after complete response to chemotherapy (Central Oncology Group protocols 7130, 7131, and 7131A). Cancer 53:1299-1305, 1984
    • (1984) Cancer , vol.53 , pp. 1299-1305
    • Hill G.J. II1    Krementz, E.T.2    Hill, H.Z.3
  • 6
    • 0026551390 scopus 로고
    • Effective combination chemo/hormonal therapy for malignant melanoma: Experience with three clinical trials
    • McClay EF, Mastrangelo MJ, Berd D, et al: Effective combination chemo/hormonal therapy for malignant melanoma: Experience with three clinical trials. Int J Cancer 50:553-556, 1992
    • (1992) Int J Cancer , vol.50 , pp. 553-556
    • McClay, E.F.1    Mastrangelo, M.J.2    Berd, D.3
  • 7
    • 0025837770 scopus 로고
    • Improved results with the addition of interferon alpha-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma
    • Falkson CI, Falkson G, Falkson HC: Improved results with the addition of interferon alpha-2b to dacarbazine in the treatment of patients with metastatic malignant melanoma. J Clin Oncol 9:1403-1408, 1991
    • (1991) J Clin Oncol , vol.9 , pp. 1403-1408
    • Falkson, C.I.1    Falkson, G.2    Falkson, H.C.3
  • 8
    • 17944398659 scopus 로고
    • Interferon alfa-2a does not improve response or survival when combined with dacarbazine in metastatic malignant melanoma: Results of a multi-institutional Australian randomized trial, QMP8704
    • Thompson D, Adena M, McLeod GRC: Interferon alfa-2a does not improve response or survival when combined with dacarbazine in metastatic malignant melanoma: Results of a multi-institutional Australian randomized trial, QMP8704. Melanoma Res 3:133-138, 1993
    • (1993) Melanoma Res , vol.3 , pp. 133-138
    • Thompson, D.1    Adena, M.2    McLeod, G.R.C.3
  • 9
    • 0028218050 scopus 로고
    • Multicenter randomized trial of dacarbazine alone or in combination with two different doses and schedules of interferon alfa-2A in the treatment of advanced melanoma
    • Bajetta E, Di Leo A, Zampino M, et al: Multicenter randomized trial of dacarbazine alone or in combination with two different doses and schedules of interferon alfa-2A in the treatment of advanced melanoma. J Clin Oncol 12:806-811, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 806-811
    • Bajetta, E.1    Di Leo, A.2    Zampino, M.3
  • 11
    • 8944261598 scopus 로고    scopus 로고
    • Randomized, double-blind placebo-controlled trial comparing the response rates of carmustine, dacarbazine and cisplatin with and without tamoxifen in patients with metastatic melanoma: National cancer institute of Canada clinical trials group
    • Rusthoven JJ, Quirt IC, Iscoe NA, et al: Randomized, double-blind placebo-controlled trial comparing the response rates of carmustine, dacarbazine and cisplatin with and without tamoxifen in patients with metastatic melanoma: National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 14:2083-2090, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 2083-2090
    • Rusthoven, J.J.1    Quirt, I.C.2    Iscoe, N.A.3
  • 12
    • 0031805725 scopus 로고    scopus 로고
    • Phase III trial of dacarbazine versus dacarbazine with interferon-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon-2b and tamoxifen in patients with metastatic malignant melanoma: An eastern cooperative oncology group study
    • Falkson CI, Ibrahim J, Kirkwood J, et al: Phase III trial of dacarbazine versus dacarbazine with interferon-2b versus dacarbazine with tamoxifen versus dacarbazine with interferon-2b and tamoxifen in patients with metastatic malignant melanoma: An Eastern Cooperative Oncology Group study. J Clin Oncol 16:1743-1751, 1998
    • (1998) J Clin Oncol , vol.16 , pp. 1743-1751
    • Falkson, C.I.1    Ibrahim, J.2    Kirkwood, J.3
  • 13
    • 0000582197 scopus 로고    scopus 로고
    • The role of cytotoxic chemotherapeutic agents either alone or in combination with biological response modifiers
    • Kirkwood JM (ed). New York, NY, Marcel Dekker
    • Atkins MB: The role of cytotoxic chemotherapeutic agents either alone or in combination with biological response modifiers, in Kirkwood JM (ed): Molecular Diagnosis, Prevention & Therapy of Melanoma. New York, NY, Marcel Dekker, 1998, pp 219-251
    • (1998) Molecular Diagnosis, Prevention & Therapy of Melanoma , pp. 219-251
    • Atkins, M.B.1
  • 14
    • 0017199306 scopus 로고
    • Selective in vitro growth of T lymphocytes for normal human bone marrows
    • Morgan DA, Ruscetti FW, Gallo R: Selective in vitro growth of T lymphocytes for normal human bone marrows. Science 193:1007-1008, 1976
    • (1976) Science , vol.193 , pp. 1007-1008
    • Morgan, D.A.1    Ruscetti, F.W.2    Gallo, R.3
  • 15
    • 0020699991 scopus 로고
    • Structure and expression of cloned cDNA for human interleukin-2
    • Taniguchi T, Matsui H, Fujita T, et al: Structure and expression of cloned cDNA for human interleukin-2. Nature 302:305-310, 1983
    • (1983) Nature , vol.302 , pp. 305-310
    • Taniguchi, T.1    Matsui, H.2    Fujita, T.3
  • 16
    • 0021837706 scopus 로고
    • Regression of established pulmonary metetastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2
    • Rosenberg SA, Mule JJ, Speiss PJ, et al: Regression of established pulmonary metetastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2. J Exp Med 161:1169-1188, 1985
    • (1985) J Exp Med , vol.161 , pp. 1169-1188
    • Rosenberg, S.A.1    Mule, J.J.2    Speiss, P.J.3
  • 17
    • 0022349817 scopus 로고
    • Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer
    • Rosenberg SA, Lotze MT, Muul LM, et al: Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer. N Engl J Med 313:1485-1492, 1985
    • (1985) N Engl J Med , vol.313 , pp. 1485-1492
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3
  • 18
    • 0023115642 scopus 로고
    • A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone
    • Rosenberg SA, Lotze MT, Muul LM, et al: A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. N Engl J Med 316:889-897, 1987
    • (1987) N Engl J Med , vol.316 , pp. 889-897
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3
  • 19
    • 0028929682 scopus 로고
    • Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
    • Fyfe G, Fisher RI, Rosenberg SA, et al: Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J Clin Oncol 13:688-696, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 688-696
    • Fyfe, G.1    Fisher, R.I.2    Rosenberg, S.A.3
  • 20
    • 0025085675 scopus 로고
    • Interleukin-2 therapy in patients with metastatic malignant melanoma: A phase II study
    • Parkinson D, Abrams J, Wiernik P, et al: Interleukin-2 therapy in patients with metastatic malignant melanoma: A phase II study. J Clin Oncol 8:1650-1656, 1990
    • (1990) J Clin Oncol , vol.8 , pp. 1650-1656
    • Parkinson, D.1    Abrams, J.2    Wiernik, P.3
  • 21
    • 0028266553 scopus 로고
    • Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2
    • Rosenberg SA, Yang JC, Topalian SL, et al: Treatment of 283 consecutive patients with metastatic melanoma or renal cell cancer using high-dose bolus interleukin 2. JAMA 271:907-913, 1994
    • (1994) JAMA , vol.271 , pp. 907-913
    • Rosenberg, S.A.1    Yang, J.C.2    Topalian, S.L.3
  • 22
    • 0002027157 scopus 로고
    • The modified group C experience: Phase III randomized trials of IL-2 vs. IL-2/LAK in advanced renal cell carcinoma and advanced melanoma
    • abstr
    • McCabe MS, Stablein D, Hawkins MJ, et al: The Modified Group C experience: Phase III randomized trials of IL-2 vs. IL-2/LAK in advanced renal cell carcinoma and advanced melanoma. Proc Am Soc Clin Oncol 10:213a, 1991 (abstr)
    • (1991) Proc Am Soc Clin Oncol , vol.10
    • McCabe, M.S.1    Stablein, D.2    Hawkins, M.J.3
  • 23
    • 0020396015 scopus 로고
    • Toxicity and response criteria of the eastern cooperative oncology group
    • Oken MM, Creech R, Tormey DC, et al: Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 5:649-655, 1982
    • (1982) Am J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.2    Tormey, D.C.3
  • 24
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan EL, Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 26
    • 0030030347 scopus 로고    scopus 로고
    • Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The eastern cooperative oncology group trial EST 1684
    • Kirkwood JM, Strawderman MH, Ernstoff MS, et al: Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: The Eastern Cooperative Oncology Group trial EST 1684. J Clin Oncol 14:7-17, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 7-17
    • Kirkwood, J.M.1    Strawderman, M.H.2    Ernstoff, M.S.3
  • 27
    • 0000656095 scopus 로고    scopus 로고
    • Biologic therapy
    • Balch CM, Houghton AN, Sober AJ, et al (eds). St Louis, MO, Quality Medical Publishing
    • Chapman PB, Parkinson DR, Kirkwood JM: Biologic therapy, in Balch CM, Houghton AN, Sober AJ, et al (eds): Cutaneous Melanoma (ed 3). St Louis, MO, Quality Medical Publishing, 1997, pp 419-436
    • (1997) Cutaneous Melanoma (Ed 3) , pp. 419-436
    • Chapman, P.B.1    Parkinson, D.R.2    Kirkwood, J.M.3
  • 28
    • 0024490334 scopus 로고
    • Complete responses and long-term survivals after systemic chemotherapy for patients with advanced malignant melanoma
    • Ahmann DL, Creagan ET, Han RG, et al: Complete responses and long-term survivals after systemic chemotherapy for patients with advanced malignant melanoma. Cancer 63:224-227, 1989
    • (1989) Cancer , vol.63 , pp. 224-227
    • Ahmann, D.L.1    Creagan, E.T.2    Han, R.G.3
  • 29
    • 0001995951 scopus 로고    scopus 로고
    • Systemic chemotherapy and biochemotherapy
    • Balch CM, Houghton AN, Sober AJ, et al (eds). St Louis, MO, Quality Medical Publishing
    • Buzaid AC, Bedikian A, Houghton AN: Systemic chemotherapy and biochemotherapy, in Balch CM, Houghton AN, Sober AJ, et al (eds): Cutaneous Melanoma (ed 3). St Louis, MO, Quality Medical Publishing, 1997, pp 405-418
    • (1997) Cutaneous Melanoma (Ed 3) , pp. 405-418
    • Buzaid, A.C.1    Bedikian, A.2    Houghton, A.N.3
  • 30
    • 0002013401 scopus 로고
    • The clinical toxicities of high-dose interleukin-2
    • Atkins MB, Mier JW (eds). New York, NY, Marcel Dekker
    • Margolin K: The clinical toxicities of high-dose interleukin-2, in Atkins MB, Mier JW (eds): Therapeutic Applications of Interleukin-2 (ed 1). New York, NY, Marcel Dekker, 1993, pp 331-362
    • (1993) Therapeutic Applications of Interleukin-2 (Ed 1) , pp. 331-362
    • Margolin, K.1
  • 31
    • 0000189247 scopus 로고
    • Biologic therapy with interleukin-2: Clinical applications - Principles of administration and management of side effects
    • DeVita V, Hellman S, Rosenberg SA (eds), Philadelphia, PA, Lippincott
    • Schwartzentruber DJ: Biologic therapy with interleukin-2: Clinical applications - Principles of administration and management of side effects, in DeVita V, Hellman S, Rosenberg SA (eds): Biologic Therapy of Cancer (ed 2), Philadelphia, PA, Lippincott, 1995, pp 235-249
    • (1995) Biologic Therapy of Cancer (Ed 2) , pp. 235-249
    • Schwartzentruber, D.J.1
  • 32
    • 0025265045 scopus 로고
    • An acquired chemotactic defect in neutrophils from patients receiving interleukin-2 immunotherapy
    • Klempner MS, Noring R, Mier JW, et al: An acquired chemotactic defect in neutrophils from patients receiving interleukin-2 immunotherapy. N Engl J Med 322:959-965, 1990
    • (1990) N Engl J Med , vol.322 , pp. 959-965
    • Klempner, M.S.1    Noring, R.2    Mier, J.W.3
  • 33
    • 0000428754 scopus 로고
    • Infectious complications associated with interleukin-2
    • Atkins MB, Mier JW (eds). New York, NY, Marcel Dekker
    • Klempner MS, Snydman DR: Infectious complications associated with interleukin-2, in Atkins MB, Mier JW (eds): Therapeutic Applications of Interleukin-2 (ed 1). New York, NY, Marcel Dekker, 1993, pp 409-424
    • (1993) Therapeutic Applications of Interleukin-2 (Ed 1) , pp. 409-424
    • Klempner, M.S.1    Snydman, D.R.2
  • 34
    • 0025250697 scopus 로고
    • Inhibition of interleukin-2 induced tumor necrosis factor release by dexamethasone: Prevention of an acquired neutrophil chemotactic defect and differential suppression of interleukin-2 associated side effects
    • Mier JW, Vachino G, Klempner MS, et al: Inhibition of interleukin-2 induced tumor necrosis factor release by dexamethasone: Prevention of an acquired neutrophil chemotactic defect and differential suppression of interleukin-2 associated side effects. Blood 76:1933-1940, 1990
    • (1990) Blood , vol.76 , pp. 1933-1940
    • Mier, J.W.1    Vachino, G.2    Klempner, M.S.3
  • 35
    • 9544240332 scopus 로고    scopus 로고
    • Aphase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera
    • Trehu EG, Mier JW, Shapiro L, et al: Aphase I trial of interleukin 2 in combination with the soluble tumor necrosis factor receptor p75 IgG chimera. Clin Cancer Res 2:1341-1351, 1996
    • (1996) Clin Cancer Res , vol.2 , pp. 1341-1351
    • Trehu, E.G.1    Mier, J.W.2    Shapiro, L.3
  • 36
    • 0031043250 scopus 로고    scopus 로고
    • Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma
    • DuBois JS, Trehu EG, Mier JW, et al: Randomized placebo-controlled clinical trial of high-dose interleukin-2 in combination with a soluble p75 tumor necrosis factor receptor immunoglobulin G chimera in patients with advanced melanoma and renal cell carcinoma. J Clin Oncol 15:1052-1062, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 1052-1062
    • DuBois, J.S.1    Trehu, E.G.2    Mier, J.W.3
  • 37
    • 15644364246 scopus 로고    scopus 로고
    • Phase I clinical trial of the soluble IL-1 receptor either alone or in combination with high-dose IL-2 in patients with advanced malignancies
    • McDermott D, Trehu E, DuBois J, et al: Phase I clinical trial of the soluble IL-1 receptor either alone or in combination with high-dose IL-2 in patients with advanced malignancies. Clin Cancer Res 5:1203-1213, 1998
    • (1998) Clin Cancer Res , vol.5 , pp. 1203-1213
    • McDermott, D.1    Trehu, E.2    DuBois, J.3
  • 38
    • 8244253669 scopus 로고    scopus 로고
    • Prospective randomized trial of lisofylline (CT1501 R) for the modulation of interleukin-2 (IL-2) toxicity
    • Margolin K, Weiss G, Dutcher J, et al: Prospective randomized trial of lisofylline (CT1501 R) for the modulation of interleukin-2 (IL-2) toxicity. Clin Cancer Res 3:565-572, 1997
    • (1997) Clin Cancer Res , vol.3 , pp. 565-572
    • Margolin, K.1    Weiss, G.2    Dutcher, J.3
  • 39
    • 84871468966 scopus 로고    scopus 로고
    • CNI-1493 blocks the toxicity of interleukin-2 (IL-2) but does not disturb the antineoplastic response
    • abstr 723
    • Kemeny MM, Ochani M, Tracey KJ: CNI-1493 blocks the toxicity of interleukin-2 (IL-2) but does not disturb the antineoplastic response. Proc Am Soc Clin Oncol 15:272a, 1996 (abstr 723)
    • (1996) Proc Am Soc Clin Oncol , vol.15
    • Kemeny, M.M.1    Ochani, M.2    Tracey, K.J.3
  • 40
    • 0026718336 scopus 로고
    • Phase II study of subcutaneous interleukin-2 in unselected patients with advanced renal cell cancer on an outpatient basis
    • Sleijfer DT, Janssen RAJ, Butler J, et al: Phase II study of subcutaneous interleukin-2 in unselected patients with advanced renal cell cancer on an outpatient basis. J Clin Oncol 10:1119-1123, 1992
    • (1992) J Clin Oncol , vol.10 , pp. 1119-1123
    • Sleijfer, D.T.1    Janssen, R.A.J.2    Butler, J.3
  • 41
    • 0028809089 scopus 로고
    • Multi-institutional home therapy trial of recombinant human interleukin-2 and interferon alfa-2 in progressive metastatic renal cell carcinoma
    • tzpodien J, Lopez HE, Kirchner H, et al: Multi-institutional home therapy trial of recombinant human interleukin-2 and interferon alfa-2 in progressive metastatic renal cell carcinoma. J Clin Oncol 13:497-501, 1995
    • (1995) J Clin Oncol , vol.13 , pp. 497-501
    • Tzpodien, J.1    Lopez, H.E.2    Kirchner, H.3
  • 42
    • 0028106484 scopus 로고
    • Randomized comparison of high-dose and low-dose intravenous interleukin-2 for the therapy of metastatic renal cell carcinoma: An interim report
    • Yang JC, Topalian SL, Parkinson D, et al: Randomized comparison of high-dose and low-dose intravenous interleukin-2 for the therapy of metastatic renal cell carcinoma: An interim report. J Clin Oncol 12:1572-1576, 1994
    • (1994) J Clin Oncol , vol.12 , pp. 1572-1576
    • Yang, J.C.1    Topalian, S.L.2    Parkinson, D.3
  • 43
    • 0000200416 scopus 로고    scopus 로고
    • IL-2 based therapy in metastatic renal cell cancer (MRCC): Cytokine Working Group (CWG) experience
    • abstr 1166
    • Dutcher J, Atkins MB, Fisher RI, et al: IL-2 based therapy in metastatic renal cell cancer (MRCC): Cytokine Working Group (CWG) experience. Proc Am Soc Clin Oncol 16:327a, 1997 (abstr 1166)
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • Dutcher, J.1    Atkins, M.B.2    Fisher, R.I.3
  • 44
    • 0028802721 scopus 로고
    • Systemic treatments for advanced cutaneous melanoma
    • Anderson CM, Buzaid A, Legha S: Systemic treatments for advanced cutaneous melanoma. Oncology 9:1149-1158, 1995
    • (1995) Oncology , vol.9 , pp. 1149-1158
    • Anderson, C.M.1    Buzaid, A.2    Legha, S.3
  • 45
    • 0031424902 scopus 로고    scopus 로고
    • Development and results of biochemotherapy in metastatic melanoma: The university of Texas M.D. Anderson cancer center experience
    • Legha SS, Sigrid R, Eton O, et al: Development and results of biochemotherapy in metastatic melanoma: The University of Texas M.D. Anderson Cancer Center experience. Cancer J Sci Am 3:S9-S15, 1997 (suppl 1)
    • (1997) Cancer J Sci Am , vol.3 , Issue.SUPPL. 1
    • Legha, S.S.1    Sigrid, R.2    Eton, O.3
  • 46
    • 0000709971 scopus 로고    scopus 로고
    • A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine (CVD), interleukin-2 (IL-2) and interferon alpha-2b (IFN) in patients with metastatic melanoma
    • abstr 1956
    • McDermott DF, Mier JW, Lawrence DP, et al: A phase II pilot trial of concurrent biochemotherapy with cisplatin, vinblastine, dacarbazine (CVD), interleukin-2 (IL-2) and interferon alpha-2b (IFN) in patients with metastatic melanoma. Proc Am Soc Clin Oncol 17:507a, 1998 (abstr 1956)
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • McDermott, D.F.1    Mier, J.W.2    Lawrence, D.P.3
  • 47
    • 0001677057 scopus 로고    scopus 로고
    • Phase II trial of concurrent biochemotherapy (c-BC) with decrescendo interleukin-2 (d-IL-2), tamoxifen (T), and G-CSF support in patients with metastatic melanoma (MM)
    • abstr 1763
    • O'Day SJ, Boasberg P, Guo M, et al: Phase II trial of concurrent biochemotherapy (c-BC) with decrescendo interleukin-2 (d-IL-2), tamoxifen (T), and G-CSF support in patients with metastatic melanoma (MM). Proc Am Soc Clin Oncol 16:490a, 1997 (abstr 1763)
    • (1997) Proc Am Soc Clin Oncol , vol.16
    • O'Day, S.J.1    Boasberg, P.2    Guo, M.3
  • 48
    • 0031424974 scopus 로고    scopus 로고
    • Updated analysis of an outpatient chemoimmunotherapy regimen for treating metastatic melanoma
    • Thompson JA, Gold PJ, Markowitz DR, et al: Updated analysis of an outpatient chemoimmunotherapy regimen for treating metastatic melanoma. Cancer J Sci Am 3:S29-S34, 1997 (suppl 1)
    • (1997) Cancer J Sci Am , vol.3 , Issue.SUPPL. 1
    • Thompson, J.A.1    Gold, P.J.2    Markowitz, D.R.3
  • 49
    • 0040231591 scopus 로고    scopus 로고
    • Biochemotherapy for metastatic melanoma: The rationale for the intergroup phase III trial
    • Atkins MB: Biochemotherapy for metastatic melanoma: The rationale for the intergroup phase III trial. Biother Consid Oncol Nurses 2:1-4, 1997
    • (1997) Biother Consid Oncol Nurses , vol.2 , pp. 1-4
    • Atkins, M.B.1
  • 50
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • Rosenberg SA, Yang JC, Schwartzentruber DJ, et al: Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat Med 4:321-327, 1998
    • (1998) Nat Med , vol.4 , pp. 321-327
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3


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