메뉴 건너뛰기




Volumn 110, Issue 49, 2013, Pages 19902-19907

Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; NANOCARRIER;

EID: 84889650175     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313152110     Document Type: Article
Times cited : (233)

References (42)
  • 2
    • 84864140479 scopus 로고    scopus 로고
    • Engineering nano- and microparticles to tune immunity
    • Moon JJ, Huang B, Irvine DJ (2012) Engineering nano- and microparticles to tune immunity. Adv Mater 24(28):3724-3746.
    • (2012) Adv Mater , vol.24 , Issue.28 , pp. 3724-3746
    • Moon, J.J.1    Huang, B.2    Irvine, D.J.3
  • 3
    • 84877057838 scopus 로고    scopus 로고
    • Materials based tumor immunotherapy vaccines
    • Li WA, Mooney DJ (2013) Materials based tumor immunotherapy vaccines. Curr Opin Immunol 25(2):238-245.
    • (2013) Curr Opin Immunol , vol.25 , Issue.2 , pp. 238-245
    • Li, W.A.1    Mooney, D.J.2
  • 4
    • 51549096629 scopus 로고    scopus 로고
    • Targeting CpG oligonucleotides to the lymph node by nanoparticles elicits efficient antitumoral immunity
    • Bourquin C, et al. (2008) Targeting CpG oligonucleotides to the lymph node by nanoparticles elicits efficient antitumoral immunity. J Immunol 181(5):2990-2998.
    • (2008) J Immunol , vol.181 , Issue.5 , pp. 2990-2998
    • Bourquin, C.1
  • 5
    • 68249106468 scopus 로고    scopus 로고
    • Vivo studies on the effect of co-encapsulation of CpG DNA and antigen in acid-degradable microparticle vaccines
    • Beaudette TT, et al. (2009) In vivo studies on the effect of co-encapsulation of CpG DNA and antigen in acid-degradable microparticle vaccines. Mol Pharm 6(4): 1160-1169.
    • (2009) Mol Pharm , vol.6 , Issue.4 , pp. 1160-1169
    • Beaudette, T.T.1
  • 6
    • 84884676871 scopus 로고    scopus 로고
    • Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination
    • ra130
    • Li AV, et al. (2013) Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination. Sci Transl Med 5(204):ra130.
    • (2013) Sci Transl Med , vol.5 , pp. 204
    • Li, A.V.1
  • 7
    • 84885378665 scopus 로고    scopus 로고
    • Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant
    • Hafner AM, Corthésy B, Merkle HP (2013) Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant. Adv Drug Deliv Rev 65(10):1386-1399.
    • (2013) Adv Drug Deliv Rev , vol.65 , Issue.10 , pp. 1386-1399
    • Hafner, A.M.1    Corthésy, B.2    Merkle, H.P.3
  • 8
    • 84879058153 scopus 로고    scopus 로고
    • Micro and nanoparticle-based delivery systems for vaccine immunotherapy: An immunological and materials perspective
    • Leleux J, Roy K (2013) Micro and nanoparticle-based delivery systems for vaccine immunotherapy: An immunological and materials perspective. Adv Healthc Mater 2(1):72-94.
    • (2013) Adv Healthc Mater , vol.2 , Issue.1 , pp. 72-94
    • Leleux, J.1    Roy, K.2
  • 9
    • 84861687871 scopus 로고    scopus 로고
    • Stable assemblies of cationic bilayer fragments and CpG oligonucleotide with enhanced immunoadjuvant activity in vivo
    • Rozenfeld JHK, Silva SR, Ranéia PA, Faquim-Mauro E, Carmona-Ribeiro AM (2012) Stable assemblies of cationic bilayer fragments and CpG oligonucleotide with enhanced immunoadjuvant activity in vivo. J Control Release 160(2):367-373.
    • (2012) J Control Release , vol.160 , Issue.2 , pp. 367-373
    • Rozenfeld, J.H.K.1    Silva, S.R.2    Ranéia, P.A.3    Faquim-Mauro, E.4    Carmona-Ribeiro, A.M.5
  • 10
    • 44649198561 scopus 로고    scopus 로고
    • Lipid A and liposomes containing lipid A as antigens and adjuvants
    • Alving CR, Rao M (2008) Lipid A and liposomes containing lipid A as antigens and adjuvants. Vaccine 26(24):3036-3045.
    • (2008) Vaccine , vol.26 , Issue.24 , pp. 3036-3045
    • Alving, C.R.1    Rao, M.2
  • 11
    • 79960598952 scopus 로고    scopus 로고
    • Conjugation of lipid and CpG-containing oligonucleotide yields an efficient method for liposome incorporation
    • Andrews CD, Provoda CJ, Ott G, Lee K-D (2011) Conjugation of lipid and CpG-containing oligonucleotide yields an efficient method for liposome incorporation. Bioconjug Chem 22(7):1279-1286.
    • (2011) Bioconjug Chem , vol.22 , Issue.7 , pp. 1279-1286
    • Andrews, C.D.1    Provoda, C.J.2    Ott, G.3    Lee, K.-D.4
  • 12
    • 1642566566 scopus 로고    scopus 로고
    • Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects
    • Storni T, et al. (2004) Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects. J Immunol 172(3):1777-1785.
    • (2004) J Immunol , vol.172 , Issue.3 , pp. 1777-1785
    • Storni, T.1
  • 13
    • 80052339594 scopus 로고    scopus 로고
    • Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis
    • Ballester M, et al. (2011) Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis. Vaccine 29(40): 6959-6966.
    • (2011) Vaccine , vol.29 , Issue.40 , pp. 6959-6966
    • Ballester, M.1
  • 14
    • 81055130325 scopus 로고    scopus 로고
    • Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination
    • Nembrini C, et al. (2011) Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination. Proc Natl Acad Sci USA 108(44):E989-E997.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.44
    • Nembrini, C.1
  • 15
    • 78650231557 scopus 로고    scopus 로고
    • Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation
    • Hirosue S, Kourtis IC, van der Vlies AJ, Hubbell JA, Swartz MA (2010) Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation. Vaccine 28(50):7897-7906.
    • (2010) Vaccine , vol.28 , Issue.50 , pp. 7897-7906
    • Hirosue, S.1    Kourtis, I.C.2    Van Der Vlies, A.J.3    Hubbell, J.A.4    Swartz, M.A.5
  • 16
    • 77951275912 scopus 로고    scopus 로고
    • Synthesis of pyridyl disulfide-functionalized nanoparticles for conjugating thiol-containing small molecules, peptides, and proteins
    • van der Vlies AJ, O'Neil CP, Hasegawa U, Hammond N, Hubbell JA (2010) Synthesis of pyridyl disulfide-functionalized nanoparticles for conjugating thiol-containing small molecules, peptides, and proteins. Bioconjug Chem 21(4):653-662.
    • (2010) Bioconjug Chem , vol.21 , Issue.4 , pp. 653-662
    • Van Der Vlies, A.J.1    O'Neil, C.P.2    Hasegawa, U.3    Hammond, N.4    Hubbell, J.A.5
  • 17
    • 84876561994 scopus 로고    scopus 로고
    • Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice
    • Kourtis IC, et al. (2013) Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice. PLoS ONE 8(4):e61646.
    • (2013) PLoS ONE , vol.8 , Issue.4
    • Kourtis, I.C.1
  • 18
    • 78650370883 scopus 로고    scopus 로고
    • Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy
    • Foster S, Duvall CL, Crownover EF, Hoffman AS, Stayton PS (2010) Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy. Bioconjug Chem 21(12):2205-2212.
    • (2010) Bioconjug Chem , vol.21 , Issue.12 , pp. 2205-2212
    • Foster, S.1    Duvall, C.L.2    Crownover, E.F.3    Hoffman, A.S.4    Stayton, P.S.5
  • 19
    • 84859489110 scopus 로고    scopus 로고
    • CpG still rocks! Update on an accidental drug
    • Krieg AM (2012) CpG still rocks! Update on an accidental drug. Nucleic Acid Ther 22(2):77-89.
    • (2012) Nucleic Acid Ther , vol.22 , Issue.2 , pp. 77-89
    • Krieg, A.M.1
  • 20
    • 23844452449 scopus 로고    scopus 로고
    • CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells
    • Marschner A, et al. (2005) CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells. Eur J Immunol 35(8):2347-2357.
    • (2005) Eur J Immunol , vol.35 , Issue.8 , pp. 2347-2357
    • Marschner, A.1
  • 21
    • 79952515648 scopus 로고    scopus 로고
    • Regulation of effector and memory T-cell functions by type I interferon
    • Huber JP, Farrar JD (2011) Regulation of effector and memory T-cell functions by type I interferon. Immunology 132(4):466-474.
    • (2011) Immunology , vol.132 , Issue.4 , pp. 466-474
    • Huber, J.P.1    Farrar, J.D.2
  • 22
    • 0034933019 scopus 로고    scopus 로고
    • Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells
    • Krug A, et al. (2001) Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur J Immunol 31(7): 2154-2163.
    • (2001) Eur J Immunol , vol.31 , Issue.7 , pp. 2154-2163
    • Krug, A.1
  • 23
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM (2002) CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 20:709-760.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 24
    • 9144238063 scopus 로고    scopus 로고
    • Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
    • Vollmer J, et al. (2004) Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities. Eur J Immunol 34(1):251-262.
    • (2004) Eur J Immunol , vol.34 , Issue.1 , pp. 251-262
    • Vollmer, J.1
  • 25
    • 79953033726 scopus 로고    scopus 로고
    • Trafficking of B cell antigen in lymph nodes
    • Gonzalez SF, et al. (2011) Trafficking of B cell antigen in lymph nodes. Annu Rev Immunol 29:215-233.
    • (2011) Annu Rev Immunol , vol.29 , pp. 215-233
    • Gonzalez, S.F.1
  • 26
    • 35148889797 scopus 로고    scopus 로고
    • Exploiting lymphatic transport and complement activation in nanoparticle vaccines
    • Reddy ST, et al. (2007) Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nat Biotechnol 25(10):1159-1164.
    • (2007) Nat Biotechnol , vol.25 , Issue.10 , pp. 1159-1164
    • Reddy, S.T.1
  • 27
    • 20244367698 scopus 로고    scopus 로고
    • Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon-alpha induction by CpG-A in plasmacytoid dendritic cells
    • Kerkmann M, et al. (2005) Spontaneous formation of nucleic acid-based nanoparticles is responsible for high interferon-alpha induction by CpG-A in plasmacytoid dendritic cells. J Biol Chem 280(9):8086-8093.
    • (2005) J Biol Chem , vol.280 , Issue.9 , pp. 8086-8093
    • Kerkmann, M.1
  • 28
    • 39149109612 scopus 로고    scopus 로고
    • Division of labor, plasticity, and crosstalk between dendritic cell subsets
    • Pulendran B, Tang H, Denning TL (2008) Division of labor, plasticity, and crosstalk between dendritic cell subsets. Curr Opin Immunol 20(1):61-67.
    • (2008) Curr Opin Immunol , vol.20 , Issue.1 , pp. 61-67
    • Pulendran, B.1    Tang, H.2    Denning, T.L.3
  • 29
    • 40749139437 scopus 로고    scopus 로고
    • Kinetic and mechanistic requirements for helping CD8 T cells
    • Agnellini P, et al. (2008) Kinetic and mechanistic requirements for helping CD8 T cells. J Immunol 180(3):1517-1525.
    • (2008) J Immunol , vol.180 , Issue.3 , pp. 1517-1525
    • Agnellini, P.1
  • 30
    • 0038454602 scopus 로고    scopus 로고
    • Maintenance and attrition of T-cell memory
    • Sad S, Krishnan L (2003) Maintenance and attrition of T-cell memory. Crit Rev Immunol 23(1-2):129-147.
    • (2003) Crit Rev Immunol , vol.23 , Issue.1-2 , pp. 129-147
    • Sad, S.1    Krishnan, L.2
  • 31
    • 0038759097 scopus 로고    scopus 로고
    • Role of Toll-like receptors in costimulating cytotoxic T cell responses
    • Schwarz K, et al. (2003) Role of Toll-like receptors in costimulating cytotoxic T cell responses. Eur J Immunol 33(6):1465-1470.
    • (2003) Eur J Immunol , vol.33 , Issue.6 , pp. 1465-1470
    • Schwarz, K.1
  • 32
    • 78650576197 scopus 로고    scopus 로고
    • Use of defined TLR ligands as adjuvants within human vaccines
    • Duthie MS, Windish HP, Fox CB, Reed SG (2011) Use of defined TLR ligands as adjuvants within human vaccines. Immunol Rev 239(1):178-196.
    • (2011) Immunol Rev , vol.239 , Issue.1 , pp. 178-196
    • Duthie, M.S.1    Windish, H.P.2    Fox, C.B.3    Reed, S.G.4
  • 33
    • 0036738536 scopus 로고    scopus 로고
    • Conjugation of ligands at the 5′-end of CpG DNA affects immunostimulatory activity
    • Kandimalla ER, et al. (2002) Conjugation of ligands at the 5′-end of CpG DNA affects immunostimulatory activity. Bioconjug Chem 13(5):966-974.
    • (2002) Bioconjug Chem , vol.13 , Issue.5 , pp. 966-974
    • Kandimalla, E.R.1
  • 34
    • 74949085031 scopus 로고    scopus 로고
    • Peptide conjugation at the 5′-end of oligodeoxynucleotides abrogates toll-like receptor 9-mediated immune stimulatory activity
    • Putta MR, et al. (2010) Peptide conjugation at the 5′-end of oligodeoxynucleotides abrogates toll-like receptor 9-mediated immune stimulatory activity. Bioconjug Chem 21(1):39-45.
    • (2010) Bioconjug Chem , vol.21 , Issue.1 , pp. 39-45
    • Putta, M.R.1
  • 35
    • 0035996093 scopus 로고    scopus 로고
    • Effect of ciprofloxacin on lethal and sublethal challenge with endotoxin and on early cytokine responses in a murine in vivo model
    • Purswani MU, Eckert SJ, Arora HK, Noel GJ (2002) Effect of ciprofloxacin on lethal and sublethal challenge with endotoxin and on early cytokine responses in a murine in vivo model. J Antimicrob Chemother 50(1):51-58.
    • (2002) J Antimicrob Chemother , vol.50 , Issue.1 , pp. 51-58
    • Purswani, M.U.1    Eckert, S.J.2    Arora, H.K.3    Noel, G.J.4
  • 36
    • 0842312143 scopus 로고    scopus 로고
    • Lentivirally transduced dendritic cells as a tool for cancer immunotherapy
    • Breckpot K, et al. (2003) Lentivirally transduced dendritic cells as a tool for cancer immunotherapy. J Gene Med 5(8):654-667.
    • (2003) J Gene Med , vol.5 , Issue.8 , pp. 654-667
    • Breckpot, K.1
  • 37
    • 84874279765 scopus 로고    scopus 로고
    • Relevance of long-lived CD8(+) T effector memory cells for protective immunity elicited by heterologous prime-boost vaccination
    • Vasconcelos JR, et al. (2012) Relevance of long-lived CD8(+) T effector memory cells for protective immunity elicited by heterologous prime-boost vaccination. Front Immunol 3:358.
    • (2012) Front Immunol , vol.3 , pp. 358
    • Vasconcelos, J.R.1
  • 38
    • 12144290582 scopus 로고    scopus 로고
    • CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro
    • Rothenfusser S, et al. (2004) CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro. Blood 103(6):2162-2169.
    • (2004) Blood , vol.103 , Issue.6 , pp. 2162-2169
    • Rothenfusser, S.1
  • 39
    • 41149096579 scopus 로고    scopus 로고
    • T-cell quality in memory and protection: Implications for vaccine design
    • Seder RA, Darrah PA, Roederer M (2008) T-cell quality in memory and protection: Implications for vaccine design. Nat Rev Immunol 8(4):247-258.
    • (2008) Nat Rev Immunol , vol.8 , Issue.4 , pp. 247-258
    • Seder, R.A.1    Darrah, P.A.2    Roederer, M.3
  • 40
  • 41
    • 33846592824 scopus 로고    scopus 로고
    • Th1 cell adjuvant therapy combined with tumor vaccination: A novel strategy for promoting CTL responses while avoiding the accumulation of Tregs
    • Zhang Y, et al. (2007) Th1 cell adjuvant therapy combined with tumor vaccination: A novel strategy for promoting CTL responses while avoiding the accumulation of Tregs. Int Immunol 19(2):151-161.
    • (2007) Int Immunol , vol.19 , Issue.2 , pp. 151-161
    • Zhang, Y.1
  • 42
    • 3242771187 scopus 로고    scopus 로고
    • The rate of the CD8- dependent initial reduction in tumor volume is not limited by contact-dependent perforin, Fas ligand, or TNF-mediated cytolysis
    • Hollenbaugh JA, Reome J, Dobrzanski M, Dutton RW (2004) The rate of the CD8- dependent initial reduction in tumor volume is not limited by contact-dependent perforin, Fas ligand, or TNF-mediated cytolysis. J Immunol 173(3):1738-1743.
    • (2004) J Immunol , vol.173 , Issue.3 , pp. 1738-1743
    • Hollenbaugh, J.A.1    Reome, J.2    Dobrzanski, M.3    Dutton, R.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.