메뉴 건너뛰기




Volumn 117, Issue 1, 2006, Pages 78-88

Enhanced and prolonged cross-presentation following endosomal escape of exogenous antigens encapsulated in biodegradable nanoparticles

Author keywords

Antigen presentation processing; Dendritic cells; Vaccination

Indexed keywords

ANTIGEN; INTERLEUKIN 2; LATEX; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OVALBUMIN; PEPTIDE DERIVATIVE; POLYGLACTIN; SERYLISOLEUCYLISOLEUCYLASPARAGYLPHENYLALANYLGLUTAMINYLLYSYLLEUCINE; UNCLASSIFIED DRUG; BIOMATERIAL; BOVINE SERUM ALBUMIN; HLA ANTIGEN CLASS 2; LACTIC ACID; NANOMATERIAL; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER;

EID: 33644831362     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2005.02268.x     Document Type: Article
Times cited : (355)

References (62)
  • 1
    • 0033062377 scopus 로고    scopus 로고
    • + T cell responses to infectious agents, tumors, transplants, and vaccines
    • + T cell responses to infectious agents, tumors, transplants, and vaccines Adv Immunol 1999 73 1 77
    • (1999) Adv Immunol , vol.73 , pp. 1-77
    • Yewdell, J.W.1    Norbury, C.C.2    Bennink, J.R.3
  • 2
    • 0017126775 scopus 로고
    • Cross-priming for a secondary cytotoxic response to minor H-antigens with H-2 congenic cells which do not cross-react in cytotoxic assay
    • Bevan MJ Cross-priming for a secondary cytotoxic response to minor H-antigens with H-2 congenic cells which do not cross-react in cytotoxic assay J Exp Med 1976 143 1283 8
    • (1976) J Exp Med , vol.143 , pp. 1283-8
    • Bevan, M.J.1
  • 3
    • 2942541735 scopus 로고    scopus 로고
    • Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens
    • Heath WR Belz GT Behrens GMN et al. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens Immunol Rev 2004 199 9 26
    • (2004) Immunol Rev , vol.199 , pp. 9-26
    • Heath, W.R.1    Belz, G.T.2    Behrens, G.M.N.3
  • 5
    • 0033522179 scopus 로고    scopus 로고
    • Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen
    • Sigal LJ Crotty S Andino R Rock KL Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen Nature 1999 398 77 80
    • (1999) Nature , vol.398 , pp. 77-80
    • Sigal, L.J.1    Crotty, S.2    Andino, R.3    Rock, K.L.4
  • 6
    • 0025030522 scopus 로고
    • Presentation of exogenous antigen with class-I major histocompatibility complex molecules
    • Rock KL Gamble S Rothstein L Presentation of exogenous antigen with class-I major histocompatibility complex molecules Science 1990 249 918 21
    • (1990) Science , vol.249 , pp. 918-21
    • Rock, K.L.1    Gamble, S.2    Rothstein, L.3
  • 7
    • 0842303169 scopus 로고    scopus 로고
    • New tools for antigen delivery to the MHC class I pathway
    • Moron G Dadaglio G Leclerc C New tools for antigen delivery to the MHC class I pathway Trends Immunol 2004 25 92 7
    • (2004) Trends Immunol , vol.25 , pp. 92-7
    • Moron, G.1    Dadaglio, G.2    Leclerc, C.3
  • 8
    • 0028052101 scopus 로고
    • Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class-I MHC molecules
    • Harding CV Song R Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class-I MHC molecules J Immunol 1994 153 4925 33
    • (1994) J Immunol , vol.153 , pp. 4925-33
    • Harding, C.V.1    Song, R.2
  • 9
    • 0029887715 scopus 로고    scopus 로고
    • Analysis of the role of MHC class II presentation in the stimulation of cytotoxic T lymphocytes by antigens targeted into the exogenous antigen-MHC class I presentation pathway
    • Rock KL Clark K Analysis of the role of MHC class II presentation in the stimulation of cytotoxic T lymphocytes by antigens targeted into the exogenous antigen-MHC class I presentation pathway J Immunol 1996 156 3721 6
    • (1996) J Immunol , vol.156 , pp. 3721-6
    • Rock, K.L.1    Clark, K.2
  • 10
    • 0036197499 scopus 로고    scopus 로고
    • Targeting vaccines to dendritic cells
    • Foged C Sundblad A Hovgaard L Targeting vaccines to dendritic cells Pharm Res 2002 19 229 38
    • (2002) Pharm Res , vol.19 , pp. 229-38
    • Foged, C.1    Sundblad, A.2    Hovgaard, L.3
  • 12
    • 0034789414 scopus 로고    scopus 로고
    • Transplantation of brain cells assembled around a programmable synthetic microenvironment
    • Mahoney MJ Saltzman WM Transplantation of brain cells assembled around a programmable synthetic microenvironment Nat Biotech 2001 19 934 9
    • (2001) Nat Biotech , vol.19 , pp. 934-9
    • Mahoney, M.J.1    Saltzman, W.M.2
  • 13
    • 0036054457 scopus 로고    scopus 로고
    • Biodegradable polymer-based interleukin-12 gene delivery: Role of induced cytokines, tumor infiltrating cells and nitric oxide in anti-tumor activity
    • Maheshwari A Han S Mahato RI Kim SW Biodegradable polymer-based interleukin-12 gene delivery: Role of induced cytokines, tumor infiltrating cells and nitric oxide in anti-tumor activity Gene Ther 2002 9 1075 84
    • (2002) Gene Ther , vol.9 , pp. 1075-84
    • Maheshwari, A.1    Han, S.2    Mahato, R.I.3    Kim, S.W.4
  • 14
    • 16644395235 scopus 로고    scopus 로고
    • Delivery of tumor antigens to dendritic cells using biodegradable microspheres
    • Waeckerle-Men Y Gander B Groettrup M Delivery of tumor antigens to dendritic cells using biodegradable microspheres Methods Mol Med 2005 109 35 46
    • (2005) Methods Mol Med , vol.109 , pp. 35-46
    • Waeckerle-Men, Y.1    Gander, B.2    Groettrup, M.3
  • 15
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • Panyam J Labhasetwar V Biodegradable nanoparticles for drug and gene delivery to cells and tissue Adv Drug Del Rev 2002 55 329 47
    • (2002) Adv Drug del Rev , vol.55 , pp. 329-47
    • Panyam, J.1    Labhasetwar, V.2
  • 16
    • 0031737698 scopus 로고    scopus 로고
    • Fully mobilizing host defense: Building better vaccines
    • Raychaudhuri S Rock KL Fully mobilizing host defense: Building better vaccines Nat Biotech 1998 16 1025 31
    • (1998) Nat Biotech , vol.16 , pp. 1025-31
    • Raychaudhuri, S.1    Rock, K.L.2
  • 17
    • 0030782958 scopus 로고    scopus 로고
    • CTL responses induced by a single immunization with peptide encapsulated in biodegradable microparticles
    • Partidos CD Vohra P Jones D Farrar G Steward MW CTL responses induced by a single immunization with peptide encapsulated in biodegradable microparticles J Immunol Methods 1997 206 143 51
    • (1997) J Immunol Methods , vol.206 , pp. 143-51
    • Partidos, C.D.1    Vohra, P.2    Jones, D.3    Farrar, G.4    Steward, M.W.5
  • 18
    • 0032832125 scopus 로고    scopus 로고
    • Induction of cytotoxic T-cell responses following oral immunization with synthetic peptides encapsulated in PLG microparticles
    • Partidos CD Vohra P Jones DH Farrar G Steward MW Induction of cytotoxic T-cell responses following oral immunization with synthetic peptides encapsulated in PLG microparticles J Cont Rel 1999 62 325 32
    • (1999) J Cont Rel , vol.62 , pp. 325-32
    • Partidos, C.D.1    Vohra, P.2    Jones, D.H.3    Farrar, G.4    Steward, M.W.5
  • 19
    • 0030040893 scopus 로고    scopus 로고
    • Induction of measles virus-specific cytotoxic T-cell responses after intranasal immunization with synthetic peptides
    • Partidos CD Vohra P Steward MW Induction of measles virus-specific cytotoxic T-cell responses after intranasal immunization with synthetic peptides Immunology 1996 87 179 85
    • (1996) Immunology , vol.87 , pp. 179-85
    • Partidos, C.D.1    Vohra, P.2    Steward, M.W.3
  • 20
    • 0001552479 scopus 로고    scopus 로고
    • Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity
    • Nixon DF Hioe C Chen PD et al. Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity Vaccine 1996 14 1523 30
    • (1996) Vaccine , vol.14 , pp. 1523-30
    • Nixon, D.F.1    Hioe, C.2    Chen, P.D.3
  • 21
    • 0036805438 scopus 로고    scopus 로고
    • Analysis of poly (d,l-lactic-co-glycolic acid) nanosphere uptake by human dendritic cells and macrophages in vitro
    • Lutsiak ME Robinson DR Coester C Kwon GS Samuel J Analysis of poly ( d, l -lactic-co-glycolic acid) nanosphere uptake by human dendritic cells and macrophages in vitro Pharm Res 2002 19 1480 7
    • (2002) Pharm Res , vol.19 , pp. 1480-7
    • Lutsiak, M.E.1    Robinson, D.R.2    Coester, C.3    Kwon, G.S.4    Samuel, J.5
  • 22
    • 0037024108 scopus 로고    scopus 로고
    • Uptake of poly (d,l-lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivo
    • Newman KD Elamanchili P Kwon GS Samuel J Uptake of poly ( d, l -lactic-co-glycolic acid) microspheres by antigen-presenting cells in vivo J Biomed Mater Res 2002 60 480 6
    • (2002) J Biomed Mater Res , vol.60 , pp. 480-6
    • Newman, K.D.1    Elamanchili, P.2    Kwon, G.S.3    Samuel, J.4
  • 23
    • 17744380618 scopus 로고    scopus 로고
    • Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells
    • Denis-Mize KS Dupuis M MacKichan ML et al. Plasmid DNA adsorbed onto cationic microparticles mediates target gene expression and antigen presentation by dendritic cells Gene Ther 2000 7 2105 12
    • (2000) Gene Ther , vol.7 , pp. 2105-12
    • Denis-Mize, K.S.1    Dupuis, M.2    MacKichan, M.L.3
  • 24
    • 0037424130 scopus 로고    scopus 로고
    • Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro
    • Audran R Peter K Dannull J Men Y Scandella E Groettrup M Gander B Corradin G Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro Vaccine 2003 21 1250 5
    • (2003) Vaccine , vol.21 , pp. 1250-5
    • Audran, R.1    Peter, K.2    Dannull, J.3    Men, Y.4    Scandella, E.5    Groettrup, M.6    Gander, B.7    Corradin, G.8
  • 25
    • 0037435833 scopus 로고    scopus 로고
    • Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro
    • Sun H Pollock KG Brewer JM Analysis of the role of vaccine adjuvants in modulating dendritic cell activation and antigen presentation in vitro Vaccine 2003 21 849 55
    • (2003) Vaccine , vol.21 , pp. 849-55
    • Sun, H.1    Pollock, K.G.2    Brewer, J.M.3
  • 26
    • 4043062872 scopus 로고    scopus 로고
    • PH-triggered microparticles for peptide vaccination
    • Haining WN Anderson DG Little SR et al. pH-triggered microparticles for peptide vaccination J Immunol 2004 173 2578 85
    • (2004) J Immunol , vol.173 , pp. 2578-85
    • Haining, W.N.1    Anderson, D.G.2    Little, S.R.3
  • 28
    • 18744411513 scopus 로고    scopus 로고
    • Dendritic cell-based vaccination in solid cancer
    • Stift A Friedl J Dubsky P et al. Dendritic cell-based vaccination in solid cancer J Clin Oncol 2003 21 135 42
    • (2003) J Clin Oncol , vol.21 , pp. 135-42
    • Stift, A.1    Friedl, J.2    Dubsky, P.3
  • 29
    • 0035576891 scopus 로고    scopus 로고
    • Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression
    • Geiger JD Hutchinson RJ Hohenkirk LF et al. Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression Cancer Res 2001 61 8513 9
    • (2001) Cancer Res , vol.61 , pp. 8513-9
    • Geiger, J.D.1    Hutchinson, R.J.2    Hohenkirk, L.F.3
  • 31
    • 0033559536 scopus 로고    scopus 로고
    • Evidence for distinct intracellular signaling pathways in CD34 (+) progenitor to dendritic cell differentiation from a human cell line model
    • St Louis DC Woodcock JB Fransozo G et al. Evidence for distinct intracellular signaling pathways in CD34 (+) progenitor to dendritic cell differentiation from a human cell line model J Immunol 1999 162 3237 48
    • (1999) J Immunol , vol.162 , pp. 3237-48
    • St Louis, D.C.1    Woodcock, J.B.2    Fransozo, G.3
  • 32
    • 0037446756 scopus 로고    scopus 로고
    • Regulation of MHC class I transport in human dendritic cells and the dendritic-like cell line KG-1
    • Ackerman AL Cresswell P Regulation of MHC class I transport in human dendritic cells and the dendritic-like cell line KG-1 J Immunol 2003 170 4178 88
    • (2003) J Immunol , vol.170 , pp. 4178-88
    • Ackerman, A.L.1    Cresswell, P.2
  • 34
    • 0027317931 scopus 로고
    • Intracellular-transport of class-I MHC molecules in antigen-processing mutant-cell lines
    • Anderson KS Alexander J Wei M Cresswell P Intracellular-transport of class-I MHC molecules in antigen-processing mutant-cell lines J Immunol 1993 151 3407 19
    • (1993) J Immunol , vol.151 , pp. 3407-19
    • Anderson, K.S.1    Alexander, J.2    Wei, M.3    Cresswell, P.4
  • 35
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone-marrow cultures supplemented with granulocyte macrophage colony-stimulating factor
    • Inaba K Inaba M Romani N Aya H Deguchi M Ikehara S Muramatsu S Steinman RM Generation of large numbers of dendritic cells from mouse bone-marrow cultures supplemented with granulocyte macrophage colony-stimulating factor J Exp Med 1992 176 1693 702
    • (1992) J Exp Med , vol.176 , pp. 1693-702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Aya, H.4    Deguchi, M.5    Ikehara, S.6    Muramatsu, S.7    Steinman, R.M.8
  • 36
    • 0033049490 scopus 로고    scopus 로고
    • Intracranial delivery of recombinant nerve growth factor: Release kinetics and protein distribution for three delivery systems
    • Saltzman WM Mak MW Mahoney MJ Duenas ET Cleland JL Intracranial delivery of recombinant nerve growth factor: Release kinetics and protein distribution for three delivery systems Pharm Res 1999 16 232 40
    • (1999) Pharm Res , vol.16 , pp. 232-40
    • Saltzman, W.M.1    Mak, M.W.2    Mahoney, M.J.3    Duenas, E.T.4    Cleland, J.L.5
  • 37
    • 0035971960 scopus 로고    scopus 로고
    • A novel microencapsulated peptide vaccine against hepatitis B
    • Moynihan JS Jones DH Farrar GH Howard CR A novel microencapsulated peptide vaccine against hepatitis B Vaccine 2001 19 3292 300
    • (2001) Vaccine , vol.19 , pp. 3292-300
    • Moynihan, J.S.1    Jones, D.H.2    Farrar, G.H.3    Howard, C.R.4
  • 38
    • 0030849769 scopus 로고    scopus 로고
    • Localization, quantitation, and in situ detection of specific peptide MHC class I complexes using a monoclonal antibody
    • Porgador A Yewdell JW Deng YP Bennink JR Germain RN Localization, quantitation, and in situ detection of specific peptide MHC class I complexes using a monoclonal antibody Immunity 1997 6 715 26
    • (1997) Immunity , vol.6 , pp. 715-26
    • Porgador, A.1    Yewdell, J.W.2    Deng, Y.P.3    Bennink, J.R.4    Germain, R.N.5
  • 39
    • 0032193687 scopus 로고    scopus 로고
    • The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR-DM, and -DO molecules
    • Hammond C Denzin LK Pan M Griffith JM Geuze HJ Cresswell P The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR-DM, and -DO molecules J Immunol 1998 161 3282 91
    • (1998) J Immunol , vol.161 , pp. 3282-91
    • Hammond, C.1    Denzin, L.K.2    Pan, M.3    Griffith, J.M.4    Geuze, H.J.5    Cresswell, P.6
  • 40
    • 0025343008 scopus 로고
    • Defective presentation of endogenous antigen by a cell-line expressing class-I molecules
    • Hosken NA Bevan MJ Defective presentation of endogenous antigen by a cell-line expressing class-I molecules Science 1990 248 367 70
    • (1990) Science , vol.248 , pp. 367-70
    • Hosken, N.A.1    Bevan, M.J.2
  • 41
    • 0026446497 scopus 로고
    • A fluorometric assay for cholesterol reductase-activity
    • Yang JB Beitz DC A fluorometric assay for cholesterol reductase-activity Anal Biochem 1992 206 246 50
    • (1992) Anal Biochem , vol.206 , pp. 246-50
    • Yang, J.B.1    Beitz, D.C.2
  • 43
    • 0029815295 scopus 로고    scopus 로고
    • Exogenous antigens gain access to the major histocompatibility complex class I processing pathway in B cells by receptor-mediated uptake
    • Ke Y Kapp JA Exogenous antigens gain access to the major histocompatibility complex class I processing pathway in B cells by receptor-mediated uptake J Exp Med 1996 184 1179 84
    • (1996) J Exp Med , vol.184 , pp. 1179-84
    • Ke, Y.1    Kapp, J.A.2
  • 45
    • 2342525996 scopus 로고    scopus 로고
    • Regulation of phagosome maturation by signals from toll-like receptors
    • Blander JM Medzhitov R Regulation of phagosome maturation by signals from toll-like receptors Science 2004 304 1014 8
    • (2004) Science , vol.304 , pp. 1014-8
    • Blander, J.M.1    Medzhitov, R.2
  • 46
    • 0029927928 scopus 로고    scopus 로고
    • A new foreign policy: MHC class I molecules monitor the outside world
    • Rock KL A new foreign policy: MHC class I molecules monitor the outside world Immunol Today 1996 17 131 7
    • (1996) Immunol Today , vol.17 , pp. 131-7
    • Rock, K.L.1
  • 47
    • 3242804567 scopus 로고    scopus 로고
    • Cellular mechanisms governing cross-presentation of exogenous antigens
    • Ackerman AL Cresswell P Cellular mechanisms governing cross-presentation of exogenous antigens Nat Immunol 2004 5 678 84
    • (2004) Nat Immunol , vol.5 , pp. 678-84
    • Ackerman, A.L.1    Cresswell, P.2
  • 48
    • 4143146210 scopus 로고    scopus 로고
    • Important role of cathepsin S in generating peptides for TAP-independent MHC class I cross presentation in vivo
    • Shen L Sigal LJ Boes M Rock KL Important role of cathepsin S in generating peptides for TAP-independent MHC class I cross presentation in vivo Immunity 2004 21 155 65
    • (2004) Immunity , vol.21 , pp. 155-65
    • Shen, L.1    Sigal, L.J.2    Boes, M.3    Rock, K.L.4
  • 50
    • 0034004167 scopus 로고    scopus 로고
    • Cytoplasmic delivery of a macromolecular fluorescent probe by poly (d,l-lactic-co-glycolic acid) microspheres
    • Newman KD Kwon GS Miller GG Chlumecky V Samuel J Cytoplasmic delivery of a macromolecular fluorescent probe by poly ( d, l -lactic-co-glycolic acid) microspheres J Biomed Mat Res 2000 50 591 7
    • (2000) J Biomed Mat Res , vol.50 , pp. 591-7
    • Newman, K.D.1    Kwon, G.S.2    Miller, G.G.3    Chlumecky, V.4    Samuel, J.5
  • 51
    • 0036324712 scopus 로고    scopus 로고
    • Rapid endo-lysosomal escape of poly (d,l-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery
    • Panyam J Zhou WZ Prabha S Sahoo SK Labhasetwar V Rapid endo-lysosomal escape of poly ( d, l -lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery FASEB J 2002 16 1217 26
    • (2002) FASEB J , vol.16 , pp. 1217-26
    • Panyam, J.1    Zhou, W.Z.2    Prabha, S.3    Sahoo, S.K.4    Labhasetwar, V.5
  • 52
    • 0035869558 scopus 로고    scopus 로고
    • Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells
    • Ludewig B McCoy K Pericin M et al. Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells J Immunol 2001 166 3678 87
    • (2001) J Immunol , vol.166 , pp. 3678-87
    • Ludewig, B.1    McCoy, K.2    Pericin, M.3
  • 53
    • 0036168910 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by prolonging antigen presentation on dendritic cells
    • Wang RF Wang HY Enhancement of antitumor immunity by prolonging antigen presentation on dendritic cells Nat Biotech 2002 20 149 54
    • (2002) Nat Biotech , vol.20 , pp. 149-54
    • Wang, R.F.1    Wang, H.Y.2
  • 54
    • 0030587077 scopus 로고    scopus 로고
    • Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen GP100 modified at HLA-A*0201-binding residues
    • Parkhurst MR Salgaller ML Southwood S Robbins PF Sette A Rosenberg SA Kawakami Y Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen GP100 modified at HLA-A*0201-binding residues J Immunol 1996 157 2539 48
    • (1996) J Immunol , vol.157 , pp. 2539-48
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3    Robbins, P.F.4    Sette, A.5    Rosenberg, S.A.6    Kawakami, Y.7
  • 55
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • Rosenberg SA Yang JC Schwartzentruber DJ et al. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma Nat Med 1998 4 321 7
    • (1998) Nat Med , vol.4 , pp. 321-7
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3
  • 57
    • 0035912916 scopus 로고    scopus 로고
    • Release kinetics and immunogenicity of parvovirus microencapsulated in PLA/PLGA microspheres
    • Palinko-Biro E Ronaszeki G Merkle HP Gander B Release kinetics and immunogenicity of parvovirus microencapsulated in PLA/PLGA microspheres Int J Pharmaceut 2001 221 153 7
    • (2001) Int J Pharmaceut , vol.221 , pp. 153-7
    • Palinko-Biro, E.1    Ronaszeki, G.2    Merkle, H.P.3    Gander, B.4
  • 59
    • 0034602599 scopus 로고    scopus 로고
    • Protein encapsulation into biodegradable microspheres by a novel s/o/w emulsion method using poly (ethylene glycol) as a protein micronization adjuvant
    • Morita T Sakamura Y Horikiri Y Suzuki T Yoshino H Protein encapsulation into biodegradable microspheres by a novel s/o/w emulsion method using poly (ethylene glycol) as a protein micronization adjuvant J Cont Rel 2000 69 435 44
    • (2000) J Cont Rel , vol.69 , pp. 435-44
    • Morita, T.1    Sakamura, Y.2    Horikiri, Y.3    Suzuki, T.4    Yoshino, H.5
  • 62
    • 0031569109 scopus 로고    scopus 로고
    • Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules
    • Shen ZH Reznikoff G Dranoff G Rock KL Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules J Immunol 1997 158 2723 30
    • (1997) J Immunol , vol.158 , pp. 2723-30
    • Shen, Z.H.1    Reznikoff, G.2    Dranoff, G.3    Rock, K.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.