Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses

Journal of Controlled Release

Volumn 200, Issue , 2015, Pages 1-12

  Zeng, Qin ^a   Jiang, Hao ^a   Wang, Ting ^a   Zhang, Zhirong ^a   Gong, Tao ^a   Sun, Xun ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Cationic micelle; Cytotoxic; Draining lymph node; Polyethylenimine; T lymphocytes; Trp2 antigen peptide

Indexed keywords

ANTIGENS; BODY FLUIDS; DERMATOLOGY; ENCAPSULATION; IMMUNIZATION; LYMPHOCYTES; MAMMALS; ONCOLOGY; PEPTIDES; T-CELLS; TOXICITY; TUMORS;

ANTIGEN PEPTIDE; CATIONIC MICELLES; CYTOTOXIC; LYMPH NODE; POLYETHYLENIMINES; T LYMPHOCYTES;

MICELLES;

ADJUVANT; CATION; EPITOPE; MELANOMA ANTIGEN; POLYETHYLENEIMINE; POLYMER; STEARIC ACID; TYROSINE RELATED PROTEIN 2; UNCLASSIFIED DRUG; ANTIGEN; ANTINEOPLASTIC AGENT; IMMUNOLOGICAL ADJUVANT; MEMBRANE PROTEIN; MICELLE; PEPTIDE FRAGMENT; PEPTIDE SVYDFFVWL; STEARIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; BONE MARROW DERIVED DENDRITIC CELL; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOSE RESPONSE; DRUG DELIVERY SYSTEM; ENCAPSULATION; IMMUNIZATION; IMMUNOGENICITY; IMMUNOTHERAPY; IN VITRO STUDY; LYMPH VESSEL; MICELLE; MOUSE; NANOENCAPSULATION; NONHUMAN; SYSTEMIC CIRCULATION; TUMOR GROWTH; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DENDRITIC CELL; DRUG EFFECTS; FEMALE; IMMUNOLOGY; LYMPH NODE; MELANOMA, EXPERIMENTAL; PATHOLOGY; SKIN NEOPLASMS; TUMOR CELL LINE; TUMOR VOLUME;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS; ANTINEOPLASTIC AGENTS; CELL DIFFERENTIATION; CELL LINE, TUMOR; DENDRITIC CELLS; FEMALE; LYMPH NODES; MELANOMA, EXPERIMENTAL; MEMBRANE PROTEINS; MICE, INBRED C57BL; MICELLES; PEPTIDE FRAGMENTS; POLYETHYLENEIMINE; SKIN NEOPLASMS; STEARIC ACIDS; T-LYMPHOCYTES, CYTOTOXIC; TUMOR BURDEN;

EID: 84920270658     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.12.024     Document Type: Article

References (38)

1. M.H. Einstein, M. Baron, M.J. Levin, A. Chatterjee, R.P. Edwards, and F. Zepp Comparison of the immunogenicity and safety of Cervarix and Gardasil human papillomavirus (HPV) cervical cancer vaccines in healthy women aged 18-45 years Hum. Vaccin. 5 2009 705 719
2. E. Thara, T.B. Dorff, J.K. Pinski, and D.I. Quinn Vaccine therapy with sipuleucel-T (Provenge) for prostate cancer Maturitas 69 2011 296 303
3. A.W. Purcell, J. McCluskey, and J. Rossjohn More than one reason to rethink the use of peptides in vaccine design Nat. Rev. Drug Discov. 6 2007 404 414
4. S.D. Xiang, K. Scalzo-Inguanti, G. Minigo, A. Park, C.L. Hardy, and M. Plebanski Promising particle-based vaccines in cancer therapy Expert Rev. Vaccines 7 2008 1103 1119
5. S.G. Reed, S. Bertholet, R.N. Coler, and M. Friede New horizons in adjuvants for vaccine development Trends Immunol. 30 2009 23 32
6. K. Kondo, H. Ochi, T. Matsumoto, H. Yoshikawa, and T. Kanda Modification of human papillomavirus-like particle vaccine by insertion of the cross-reactive L2-epitopes J. Med. Virol. 80 2008 841 846
7. M.D. Joshi, W.J. Unger, G. Storm, Y. van Kooyk, and E. Mastrobattista Targeting tumor antigens to dendritic cells using particulate carriers J. Control. Release 161 2012 25 37
8. W. Chen, and L. Huang Induction of cytotoxic T-lymphocytes and antitumor activity by a liposomal lipopeptide vaccine Mol. Pharm. 5 2008 464 471
9. S.A. Jalali, M. Sankian, J. Tavakkol-Afshari, and M.R. Jaafari Induction of tumor-specific immunity by multi-epitope rat HER2/neu-derived peptides encapsulated in LPD nanoparticles Nanomedicine 8 2012 692 701
10. M. Kalariya, S. Ganta, and M. Amiji Multi-compartmental vaccine delivery system for enhanced immune response to gp100 peptide antigen in melanoma immunotherapy Pharm. Res. 29 2012 3393 3403
11. M. Black, A. Trent, Y. Kostenko, J.S. Lee, C. Olive, and M. Tirrell Self-assembled peptide amphiphile micelles containing a cytotoxic T-cell epitope promote a protective immune response in vivo Adv. Mater. 24 2012 3845 3849
12. L.M. Kaminskas, and C.J. Porter Targeting the lymphatics using dendritic polymers (dendrimers) Adv. Drug Deliv. Rev. 63 2011 890 900
13. S. Hamdy, A. Haddadi, R.W. Hung, and A. Lavasanifar Targeting dendritic cells with nano-particulate PLGA cancer vaccine formulations Adv. Drug Deliv. Rev. 63 2011 943 955
14. Z. Zhang, S. Tongchusak, Y. Mizukami, Y.J. Kang, T. Ioji, and M. Touma Induction of anti-tumor cytotoxic T cell responses through PLGA-nanoparticle mediated antigen delivery Biomaterials 32 2011 3666 3678
15. E.A. Vasievich, S. Ramishetti, Y. Zhang, and L. Huang Trp2 peptide vaccine adjuvanted with (R)-DOTAP inhibits tumor growth in an advanced melanoma model Mol. Pharm. 9 2012 261 268
16. R.M. Steinman, and J. Banchereau Taking dendritic cells into medicine Nature 449 2007 419 426
17. V. Manolova, A. Flace, M. Bauer, K. Schwarz, P. Saudan, and M.F. Bachmann Nanoparticles target distinct dendritic cell populations according to their size Eur. J. Immunol. 38 2008 1404 1413
18. S.T. Reddy, A. Rehor, H.G. Schmoekel, J.A. Hubbell, and M.A. Swartz In vivo targeting of dendritic cells in lymph nodes with poly(propylene sulfide) nanoparticles J. Control. Release 112 2006 26 34
19. X. Zhan, K.K. Tran, and H. Shen Effect of the poly(ethylene glycol) (PEG) density on the access and uptake of particles by antigen-presenting cells (APCs) after subcutaneous administration Mol. Pharm. 9 2012 3442 3451
20. S.T. Reddy, A.J. van der Vlies, E. Simeoni, V. Angeli, G.J. Randolph, and C.P. O'Neil Exploiting lymphatic transport and complement activation in nanoparticle vaccines Nat. Biotechnol. 25 2007 1159 1164
21. Y. Zhuang, Y. Ma, C. Wang, L. Hai, C. Yan, and Y. Zhang PEGylated cationic liposomes robustly augment vaccine-induced immune responses: role of lymphatic trafficking and biodistribution J. Control. Release 159 2012 135 142
22. F. Wegmann, K.H. Gartlan, A.M. Harandi, S.A. Brinckmann, M. Coccia, and W.R. Hillson Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens Nat. Biotechnol. 30 2012 883 888
23. J.F. Mann, P.F. McKay, S. Arokiasamy, R.K. Patel, K. Klein, and R.J. Shattock Pulmonary delivery of DNA vaccine constructs using deacylated PEI elicits immune responses and protects against viral challenge infection J. Control. Release 170 2013 452 459
24. P. Li, Z.C. Luo, P. Liu, N.N. Gao, Y.J. Zhang, and H. Pan Bioreducible alginate-poly(ethylenimine) nanogels as an antigen-delivery system robustly enhance vaccine-elicited humoral and cellular immune responses J. Control. Release 168 2013 271 279
25. R.M. Steinman Dendritic cells in vivo: a key target for a new vaccine science Immunity 29 2008 319 324
26. Z. Xu, S. Ramishetti, Y.C. Tseng, S. Guo, Y. Wang, and L. Huang Multifunctional nanoparticles co-delivering Trp2 peptide and CpG adjuvant induce potent cytotoxic T-lymphocyte response against melanoma and its lung metastasis J. Control. Release 172 2013 259 265
27. W.T. Godbey, K.K. Wu, and A.G. Mikos Poly(ethylenimine) and its role in gene delivery J. Control. Release 60 1999 149 160
28. M.E. Bonnet, J.B. Gossart, E. Benoit, M. Messmer, O. Zounib, and V. Moreau Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition J. Control. Release 170 2013 183 190
29. E.S. Trombetta, M. Ebersold, W. Garrett, M. Pypaert, and I. Mellman Activation of lysosomal function during dendritic cell maturation Science 299 2003 1400 1403
30. M. Lechmann, S. Berchtold, J. Hauber, and A. Steinkasserer CD83 on dendritic cells: more than just a marker for maturation Trends Immunol. 23 2002 273 275
31. M. Breloer, and B. Fleischer CD83 regulates lymphocyte maturation, activation and homeostasis Trends Immunol. 29 2008 186 194
32. C. Reis e Sousa Activation of dendritic cells: translating innate into adaptive immunity Curr. Opin. Immunol. 16 2004 21 25
33. O.A. Ali, N. Huebsch, L. Cao, G. Dranoff, and D.J. Mooney Infection-mimicking materials to program dendritic cells in situ Nat. Mater. 8 2009 151 158
34. H. Chen, P. Li, Y. Yin, X. Cai, Z. Huang, and J. Chen The promotion of type 1 T helper cell responses to cationic polymers in vivo via toll-like receptor-4 mediated IL-12 secretion Biomaterials 31 2010 8172 8180
35. Y. Ma, Y. Zhuang, X. Xie, C. Wang, F. Wang, and D. Zhou The role of surface charge density in cationic liposome-promoted dendritic cell maturation and vaccine-induced immune responses Nanoscale 3 2011 2307 2314
36. J.G. Cyster Chemokines and cell migration in secondary lymphoid organs Science 286 1999 2098 2102
37. S. Yanagihara, E. Komura, J. Nagafune, H. Watarai, and Y. Yamaguchi EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation J. Immunol. 161 1998 3096 3102
38. Y. Yang, C.T. Huang, X. Huang, and D.M. Pardoll Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance Nat. Immunol. 5 2004 508 515