Immunostimulatory sutures that treat local disease recurrence following primary tumor resection

Biomedical Materials

Volumn 6, Issue 1, 2011, Pages

  Intra, Janjira ^a   Zhang, Xue Qing ^a   Williams, Robin L ^b   Zhu, Xiaoyan ^b   Sandler, Anthony D ^c   Salem, Aliasger K ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRACKS; OLIGONUCLEOTIDES; SCANNING ELECTRON MICROSCOPY;

ANTI-TUMOR IMMUNE; CHILDHOOD CANCERS; CPG-ODN; GLYCOLIC ACIDS; LOCALIZED DELIVERY; NEUROBLASTOMAS; PHOSPHOROTHIOATES; POLY GLYCOLIC ACID; POLY LACTIC ACID; RESIDUAL DISEASE; SCANNING ELECTRON MICROSCOPY IMAGE; SUSTAINED RELEASE; TUMOR RESECTION; UV SPECTROPHOTOMETRY; VICRYL SUTURES; WILD-TYPE CELLS;

TUMORS;

CPG OLIGODEOXYNUCLEOTIDE; CPG OLIGODEOXYNUCLEOTIDE 1826; IMMUNOSTIMULATING AGENT; POLYGLACTIN; UNCLASSIFIED DRUG; BIOMATERIAL; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; IMMUNOLOGICAL ADJUVANT; LACTIC ACID; OLIGODEOXYRIBONUCLEOTIDE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SURGERY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PELLET; FEMALE; INOCULATION; MOUSE; NEUROBLASTOMA; NONHUMAN; PRIMARY TUMOR; SCANNING ELECTRON MICROSCOPY; SUTURE; TUMOR GROWTH; TUMOR RECURRENCE; ULTRAVIOLET SPECTROSCOPY; WILD TYPE; WOUND CLOSURE; A J MOUSE; ANIMAL; DELAYED RELEASE FORMULATION; EXPERIMENTAL NEOPLASM; HUMAN; IMMUNOLOGY; MATERIALS TESTING; TUMOR CELL LINE;

MURINAE; MUS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL LINE, TUMOR; DELAYED-ACTION PREPARATIONS; FEMALE; HUMANS; LACTIC ACID; MATERIALS TESTING; MICE; MICE, INBRED A; NEOPLASM RECURRENCE, LOCAL; NEOPLASMS, EXPERIMENTAL; NEUROBLASTOMA; OLIGODEOXYRIBONUCLEOTIDES; POLYGLYCOLIC ACID; SUTURES;

EID: 79551484727     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/6/1/011001     Document Type: Article

References (16)

1. Ohashi K et al 2006 Surgical excision combined with autologous whole tumor cell vaccination is an effective therapy for murine neuroblastoma J. Pediatr. Surg. 41 1361-8
2. Sandler A D et al 2003 CpG oligonucleotides enhance the tumor antigen-specific immune response of a granulocyte macrophage colony-stimulating factor-based vaccine strategy in neuroblastoma Cancer Res. 63 394-9
3. Auf G, Chen L, Fornes P, Le Clanche C, Delattre J Y and Carpentier A F 2002 CpG-oligodeoxynucleotide rejection of a neuroblastoma in A/J mice does not induce a paraneoplastic disease Neurosci. Lett. 327 189-92
4. Carpentier A F, Chen L, Maltonti F and Delattre JY 1999 Oligodeoxynucleotides containing CpG motifs can induce rejection of a neuroblastoma in mice Cancer Res. 59 5429-32
5. Weiner G J, Liu H M, Wooldridge J E, Dahle C E and Krieg A M 1997 Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization Proc. Natl Acad. Sci. USA 94 10833-7
6. Hartmann G, Weiner G J and Krieg A M 1999 CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells Proc. Natl Acad. Sci. USA 96 9305-10
7. Wang C et al 2004 Molecularly engineered poly(ortho ester) microspheres for enhanced delivery of DNA vaccines Nat. Mater. 3 190-6
8. Uhrich K E, Cannizzaro S M, Langer R S and Shakesheff K M 1999 Polymeric systems for controlled drug release Chem. Rev. 99 3181-98
9. Intra J, Glasgow J M, Mai H Q and Salem A K 2008 Pulsatile release of biomolecules from polydimethylsiloxane (PDMS) chips with hydrolytically degradable seals J. Control. Release 127 280-7
10. Zhang X Q, Dahle C E, Baman N K, Rich N, Weiner G J and Salem A K 2007 Potent antigen-specific immune responses stimulated by codelivery of CpG ODN and antigens in degradable microparticles J. Immunother. 30 469-78
11. Datta S K, Takabayashi K and Raz E 2003 The therapeutic potential of antigen-oligonucleotide conjugates Ann. NY Acad. Sci. 1002 105-11
12. Buhtoiarov I N, Sondel P M, Eickhoff J C and Rakhmilevich A L 2007 Macrophages are essential for antitumour effects against weakly immunogenic murine tumours induced by class B CpG-oligodeoxynucleotides Immunology 120 412-23
13. Krishnamachari Y and Salem A K 2009 Innovative strategies for co-delivering antigens and CpG oligonucleotides Adv. Drug Deliv. Rev. 61 205-17
14. Miles S A and Sandler A D 2009 CpG oligonucleotides for immunotherapeutic treatment of neuroblastoma Adv. Drug Deliv. Rev. 61 275-82
15. Ullman-Cullere M H and Foltz C J 1999 Body condition scoring: a rapid and accurate method for assessing health status in mice Lab. Anim. Sci. 49 319-23
16. Jones T R et al 1999 Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys Vaccine 17 3065-71