Intrinsic immunogenicity of rapidly-degradable polymers evolves during degradation

Acta Biomaterialia

Volumn 32, Issue , 2016, Pages 24-34

  Andorko, James I ^a   Hess, Krystina L ^a   Pineault, Kevin G ^a   Jewell, Christopher M ^a,b,c  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

Author keywords

Dendritic cell; Immune response and inflammation; Microparticle and nanoparticle; Poly(beta amino esters); Vaccine

Indexed keywords

ANTIGENS; BIODEGRADABLE POLYMERS; BIOMATERIALS; CELL PROLIFERATION; CHEMICAL ACTIVATION; ESTERS; IMMUNE SYSTEM; MOLECULAR WEIGHT; T-CELLS;

DENDRITIC CELL; DENDRITICS; IMMUNE RESPONSE; IMMUNE RESPONSE AND INFLAMMATION; IMMUNOGENICITY; MICRO PARTICLES; MICROPARTICLE AND NANOPARTICLE; POLIES (BETA AMINO ESTER); POLY(BETA-AMINO ESTER); VACCINE CARRIERS;

VACCINES;

BIOMATERIAL; POLYESTER; POLYMER; VACCINE; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; POLY(BETA-AMINO ESTER);

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ARTICLE; BIODEGRADATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOSTIMULATION; LYMPH NODE; LYMPHOCYTE PROLIFERATION; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PHYSICOCHEMICAL MODEL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; IMMUNITY; IMMUNOLOGY;

ANIMALS; ANTIGEN PRESENTATION; CELL PROLIFERATION; DENDRITIC CELLS; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNITY; MICE, INBRED C57BL; MOLECULAR WEIGHT; POLYMERS; T-LYMPHOCYTES;

EID: 84950349764     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2015.12.026     Document Type: Article

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