In situ modulation of dendritic cells by injectable thermosensitive hydrogels for cancer vaccines in mice

Biomacromolecules

Volumn 15, Issue 10, 2014, Pages 3836-3845

  Liu, Yarong ^a   Xiao, Liang ^a   Joo, Kye Il ^a   Hu, Biliang ^a   Fang, Jinxu ^a   Wang, Pin ^a,b  

^a University of Southern California   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; COPOLYMERS; CYTOLOGY; DISEASES; HYDROGELS; MACROPHAGES; MODULATION; MOTION PICTURE EXPERTS GROUP STANDARDS;

ANTIGEN PRESENTATION; CHEMOATTRACTANTS; DENDRITIC CELLS (DCS); GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTORS; HYBRID STRATEGIES; NONVIRAL VECTORS; SUSTAINED RELEASE; THERMO-SENSITIVE HYDROGEL;

VACCINES;

CANCER VACCINE; CHEMOATTRACTANT; COPOLYMER; DENDRITIC CELL VACCINE; DRUG CARRIER; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MONOMETHOXYPOLY(ETHYLENE GLYCOL) CO POLY(LACTIC CO GLYCOLIC ACID); TUMOR ANTIGEN; UNCLASSIFIED DRUG; VIRUS VECTOR; HYDROGEL; IMMUNOLOGICAL ADJUVANT; MACROGOL DERIVATIVE; METHOXYPOLYETHYLENEGLYCOL-POLY(LACTIC-CO-GLYCOLIC ACID); POLYESTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; CANCER IMMUNIZATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; HYDROGEL; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; MOUSE; NONHUMAN; TREATMENT OUTCOME; TUMOR IMMUNITY; ADMINISTRATION AND DOSAGE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; NEOPLASM;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, NEOPLASM; CANCER VACCINES; DENDRITIC CELLS; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HYDROGELS; MICE; MICE, INBRED C57BL; NEOPLASMS; POLYESTERS; POLYETHYLENE GLYCOLS;

EID: 84907980704     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm501166j     Document Type: Article

References (35)

1. Trombetta, E. S.; Mellman, I. Cell Biology of Antigen Processing In Vitro and In Vivo Annu. Rev. Immunol. 2005, 23, 975-1028
2. Banchereau, J.; Steinman, R. Dendritic Cells and the Control of Immunity Nature 1998, 392, 245-252
3. Mellman, I.; Steinman, R. M. Dendritic Cells: Specialized and Regulated Antigen Processing Machines Cell 2001, 106, 255-258
4. Banchereau, J.; Palucka, A. K. Dendritic Cells As Therapeutic Vaccines against Cancer Nat. Rev. Immunol. 2005, 5, 296-306
5. Nestle, F. O.; Farkas, A.; Conrad, C. Dendritic-Cell-Based Therapeutic Vaccination against Cancer Curr. Opin. Immunol. 2005, 17, 163-169
6. Steinman, R. M.; Banchereau, J. Taking Dendritic Cells into Medicine Nature 2007, 449, 419-426
7. Gilboa, E. DC-Based Cancer Vaccines J. Clin. Invest. 2007, 117, 1195-1203
8. Breckpot, K.; Aerts, J. L.; Thielemans, K. Lentiviral Vectors for Cancer Immunotherapy: Transforming Infectious Particles into Therapeutics Gene Ther. 2007, 14, 847-862
9. Dullaers, M.; Van Meirvenne, S.; Heirman, C.; Straetman, L.; Bonehill, A.; Aerts, J. L.; Thielemans, K.; Breckpot, K. Induction of Effective Therapeutic Antitumor Immunity by Direct in Vivo Administration of Lentiviral Vectors Gene Ther. 2006, 13, 630-640
10. Shiver, J. W.; Emini, E. A. Recent Advances in the Development of HIV-1 Vaccines Using Replication-Incompetent Adenovirus Vectors Annu. Rev. Med. 2004, 55, 355-372
11. O'Hagan, D. T.; Valiante, N. M. Recent Advances in the Discovery and Delivery of Vaccine Adjuvants Nat. Rev. Drug Discovery 2003, 2, 727-735
12. Zhao, X.; Jain, S.; Larman, H. B.; Gonzalez, S.; Irvine, D. J. Directed Cell Migration via Chemoattractants Released from Degradable Microspheres Biomaterials 2005, 26, 5048-5063
13. Hori, Y.; Winans, A. M.; Irvine, D. J. Modular Injectable Matrices Based on Alginate Solution/Microsphere Mixtures That Gel in Situ and Co-Deliver Immunomodulatory Factors Acta Biomater. 2009, 5, 969-982
14. Ali, O. A.; Huebsch, N.; Cao, L.; Dranoff, G.; Mooney, D. J. Infection-Mimicking Materials to Program Dendritic Cells In Situ Nat. Mater. 2009, 8, 151-158
15. Kumamoto, T.; Huang, E. K.; Paek, H. J.; Morita, A.; Matsue, H.; Valentini, R. F.; Takashima, A. Induction of Tumor-Specific Protective Immunity by In Situ Langerhans Cell Vaccine Nat. Biotechnol. 2002, 20, 64-69
16. Singh, A.; Suri, S.; Roy, K. In Situ Crosslinking Hydrogels for Combinatorial Delivery of Chemokines and siRNA-DNA Carrying Microparticles to Dendritic Cells Biomaterials 2009, 30, 5187-5200
17. Liu, Y.; Fox, V.; Lei, Y.; Hu, B.; Joo, K. I.; Wang, P. Synthetic Niches for Differentiation of Human Embryonic Stem Cells Bypassing Embryoid Body Formation J. Biomed. Mater. Res., Part B: Appl. Biomater. 2014, 102, 1101-1112
18. Nagahama, K.; Hashizume, M.; Yamamoto, H.; Ouchi, T.; Ohya, Y. Hydrophobically Modified Biodegradable Poly(ethylene glycol) Copolymers that Form Temperature-Responsive Nanogels Langmuir 2009, 25, 9734-9740
19. Peng, K.-T.; Chen, C.-F.; Chu, I.-M.; Li, Y.-M.; Hsu, W.-H.; Hsu, R. W.-W.; Chang, P.-J. Treatment of Osteomyelitis with Teicoplanin-Encapsulated Biodegradable Thermosensitive Hydrogel Nanoparticles Biomaterials 2010, 31, 5227-5236
20. Shi, Y.; Liu, C. H.; Roberts, A. I.; Das, J.; Xu, G.; Ren, G.; Zhang, Y.; Zhang, L.; Yuan, Z. R.; Tan, H. S.; Das, G.; Devadas, S. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and T-Cell Responses: What We Do and Don't Know Cell Res. 2006, 16, 126-133
21. Warren, T. L.; Weiner, G. J. Uses of Granulocyte-Macrophage Colony-Stimulating Factor in Vaccine Development Curr. Opin. Hematol. 2000, 7, 168-173
22. Yang, L.; Yang, H.; Rideout, K.; Cho, T.; Joo, K. i.; Ziegler, L.; Elliot, A.; Walls, A.; Yu, D.; Baltimore, D.; Wang, P. Engineered Lentivector Targeting of Dendritic Cells for in Vivo Immunization Nat. Biotechnol. 2008, 26, 326-334
23. Meerpohl, H. G.; Lohmann-Matthes, M. L.; Fischer, H. Studies on the Activation of Mouse Bone Marrow-Derived Macrophages by the Macrophage Cytotoxicity Factor (MCF) Eur. J. Immunol. 1976, 6, 213-217
24. Rowe, H. M.; Lopes, L.; Ikeda, Y.; Bailey, R.; Barde, I.; Zenke, M.; Chain, B. M.; Collins, M. K. Immunization with a Lentiviral Vector Stimulates Both CD4 and CD8 T Cell Responses to an Ovalbumin Transgene Mol. Ther. 2006, 13, 310-319
25. Lois, C.; Hong, E. J.; Pease, S.; Brown, E. J.; Baltimore, D. Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors Science 2002, 295, 868-872
26. Liu, Y.; Joo, K.-I.; Wang, P. Endocytic Processing of Adeno-Associated Virus Type 8 Vectors for Transduction of Target Cells Gene Ther. 2013, 20, 308-317
27. Liu, Y.; Kim, Y. J.; Ji, M.; Fang, J.; Siriwon, N.; Zhang, L. I.; Wang, P. Enhancing Gene Delivery of Adeno-Associated Viruses by Cell-Permeable Peptides Mol. Ther. Methods Clin. Dev. 2014, 1, 1-13
28. Liu, Y.; Tai, A.; Joo, K.-I.; Wang, P. Visualization of DC-SIGN-Mediated Entry Pathway of Engineered Lentiviral Vectors in Target Cells PLoS One 2013, 8, e67400
29. Kwon, Y. J.; James, E.; Shastri, N.; Fréchet, J. M. In Vivo Targeting of Dendritic Cells for Activation of Cellular Immunity Using Vaccine Carriers Based on pH-Responsive Microparticles Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 18264-8
30. Nchinda, G.; Kuroiwa, J.; Oks, M.; Trumpfheller, C.; Park, C. G.; Huang, Y.; Hannaman, D.; Schlesinger, S. J.; Mizenina, O.; Nussenzweig, M. C.; Uberla, K.; Steinman, R. M. The Efficacy of DNA Vaccination is Enhanced in Mice by Targeting the Encoded Protein to Dendritic Cells J. Clin. Invest. 2008, 118, 1427-36
31. Chou, H. Y.; Lin, X. Z.; Pan, W. Y.; Wu, P. Y.; Chang, C. M.; Lin, T. Y.; Shen, H. H.; Tao, M. H. Hydrogel-Delivered GM-CSF Overcomes Nonresponsiveness to Hepatitis B Vaccine through the Recruitment and Activation of Dendritic Cells J. Immunol. 2010, 185, 5468-75
32. Mach, N.; Dranoff, G. Cytokine-Secreting Tumor Cell Vaccines Curr. Opin. Immunol. 2000, 12, 571-575
33. Salgia, R.; Lynch, T.; Skarin, A.; Lucca, J.; Lynch, C.; Jung, K.; Hodi, F. S.; Jaklitsch, M.; Mentzer, S.; Swanson, S.; Lukanich, J.; Bueno, R.; Wain, J.; Mathisen, D.; Wright, C.; Fidias, P.; Donahue, D.; Clift, S.; Hardy, S.; Neuberg, D.; Mulligan, R.; Webb, I.; Sugarbaker, D.; Mihm, M.; Dranoff, G. Vaccination with Irradiated Autologous Tumor Cells Engineered to Secrete Granulocyte-Macrophage Colony-Stimulating Factor Augments Antitumor Immunity in Some Patients with Metastatic Non-Small-Cell Lung Carcinoma J. Clin. Oncol. 1993, 21, 624-630
34. Burke, B.; Pridmore, A.; Harraghy, N.; Collick, A.; Brown, J.; Mitchell, T. Transgenic Mice Showing Inflammation-Inducible Overexpression of Granulocyte Macrophage Colony-Stimulating Factor Clin. Vaccine Immunol. 2004, 11, 588-598
35. Nguyen, C. L.; Bui, J. T.; Demcheva, M.; Vournakis, J. N.; Cole, D. J.; Gillanders, W. E. Sustained Release of Granulocyte-Macrophage Colony-Stimulating Factor from a Modular Peptide-Based Cancer Vaccine Alters Vaccine Microenvironment and Enhances the Antigen-Specific T-Cell Response J. Immunother. 2001, 24, 420-429-429