Repression of the antioxidant NRF2 pathway in premature aging

Cell

Volumn 165, Issue 6, 2016, Pages 1361-1374

  Kubben, Nard ^a   Zhang, Weiqi ^b,c   Wang, Lixia ^b,e   Voss, Ty C ^a   Yang, Jiping ^b,e   Qu, Jing ^b,e   Liu, Guang Hui ^b,c,d,e   Misteli, Tom ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c FOSHAN UNIVERSITY   (China)

^d BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

aging; HGPS; NRF2; oxidative stress; progerin

Indexed keywords

ANTIOXIDANT; CULLIN; LAMIN A; LAMIN C; PROGERIN; PROTEIN; PROTEIN CAND1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CAND1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VIVO STUDY; MESENCHYMAL STEM CELL; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROGERIA; RNA INTERFERENCE; CELL LINE; CELL SURVIVAL; CYTOLOGY; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PREMATURE AGING;

AGING, PREMATURE; ANTIOXIDANTS; CELL LINE; CELL SURVIVAL; MESENCHYMAL STROMAL CELLS; NF-E2-RELATED FACTOR 2; PROGERIA; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84971529257     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.05.017     Document Type: Article

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