-
1
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi, K., Traver, D., Miyamoto, T. & Weissman, I.L. (2000) A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404, 193-197.
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
2
-
-
84858992660
-
Loss of transcription factor nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) leads to dysregulation of immune functions, redox homeostasis, and intracellular signaling in dendritic cells
-
Aw Yeang, H.X., Hamdam, J.M., Al-Huseini, L.M., Sethu, S., Djouhri, L., Walsh, J., Kitteringham, N., Park, B.K., Goldring, C.E. & Sathish, J.G. (2012) Loss of transcription factor nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) leads to dysregulation of immune functions, redox homeostasis, and intracellular signaling in dendritic cells. J. Biol. Chem. 287, 10556-10564.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 10556-10564
-
-
Aw Yeang, H.X.1
Hamdam, J.M.2
Al-Huseini, L.M.3
Sethu, S.4
Djouhri, L.5
Walsh, J.6
Kitteringham, N.7
Park, B.K.8
Goldring, C.E.9
Sathish, J.G.10
-
3
-
-
77953462161
-
Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection
-
Baldridge, M.T., King, K.Y., Boles, N.C., Weksberg, D.C. & Goodell, M.A. (2010) Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection. Nature 465, 793-797.
-
(2010)
Nature
, vol.465
, pp. 793-797
-
-
Baldridge, M.T.1
King, K.Y.2
Boles, N.C.3
Weksberg, D.C.4
Goodell, M.A.5
-
4
-
-
77950418688
-
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
-
Beerman, I., Bhattacharya, D., Zandi, S., Sigvardsson, M., Weissman, I.L., Bryder, D. & Rossi, D.J. (2010) Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc. Natl Acad. Sci. USA 107, 5465-5470.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 5465-5470
-
-
Beerman, I.1
Bhattacharya, D.2
Zandi, S.3
Sigvardsson, M.4
Weissman, I.L.5
Bryder, D.6
Rossi, D.J.7
-
5
-
-
84857873445
-
Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs
-
Benz, C., Copley, M.R., Kent, D.G., Wohrer, S., Cortes, A., Aghaeepour, N., Ma, E., Mader, H., Rowe, K., Day, C., Treloar, D., Brinkman, R.R. & Eaves, C.J. (2012) Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell 10, 273-283.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 273-283
-
-
Benz, C.1
Copley, M.R.2
Kent, D.G.3
Wohrer, S.4
Cortes, A.5
Aghaeepour, N.6
Ma, E.7
Mader, H.8
Rowe, K.9
Day, C.10
Treloar, D.11
Brinkman, R.R.12
Eaves, C.J.13
-
6
-
-
38049055294
-
Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance
-
Beyer, T.A., Xu, W., Teupser, D., auf dem Kelller, U., Bugnon, P., Hildt, E., Thiery, J., Kan, Y.W. & Werner, S. (2008) Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance. EMBO J. 27, 212-223.
-
(2008)
EMBO J.
, vol.27
, pp. 212-223
-
-
Beyer, T.A.1
Xu, W.2
Teupser, D.3
Auf Dem Kelller, U.4
Bugnon, P.5
Hildt, E.6
Thiery, J.7
Kan, Y.W.8
Werner, S.9
-
7
-
-
77449145533
-
Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-β1
-
Challen, G.A., Boles, N.C., Chambers, S.M. & Goodell, M.A. (2010) Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-β1. Cell Stem Cell 6, 265-278.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 265-278
-
-
Challen, G.A.1
Boles, N.C.2
Chambers, S.M.3
Goodell, M.A.4
-
8
-
-
0034672595
-
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
-
Chan, J.Y. & Kwong, M. (2000) Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein. Biochim. Biophys. Acta 1517, 19-26.
-
(2000)
Biochim. Biophys. Acta
, vol.1517
, pp. 19-26
-
-
Chan, J.Y.1
Kwong, M.2
-
9
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen, C., Liu, Y., Liu, R., Ikenoue, T., Guan, K.L., Liu, Y. & Zheng, P. (2008) TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J. Exp. Med. 205, 2397-2408.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.L.5
Liu, Y.6
Zheng, P.7
-
10
-
-
77957551487
-
Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress
-
Chuikov, S., Levi, B.P., Smith, M.L. & Morrison, S.J. (2010) Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat. Cell Biol. 12, 999-1006.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 999-1006
-
-
Chuikov, S.1
Levi, B.P.2
Smith, M.L.3
Morrison, S.J.4
-
11
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova, A.T., Holtzclaw, W.D., Cole, R.N., Itoh, K., Wakabayashi, N., Katoh, Y., Yamamoto, M. & Talalay, P. (2002) Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc. Natl Acad. Sci. USA 99, 11908-11913.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
12
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto, A., Itoh, K., Nagayoshi, E., Haruta, J., Kimura, T., O'Connor, T., Harada, T. & Yamamoto, M. (2001) High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol. Sci. 59, 169-177.
-
(2001)
Toxicol. Sci.
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
O'Connor, T.6
Harada, T.7
Yamamoto, M.8
-
13
-
-
84858649330
-
Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing
-
Ergen, A.V., Boles, N.C. & Goodell, M.A. (2012) Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood 119, 2500-2509.
-
(2012)
Blood
, vol.119
, pp. 2500-2509
-
-
Ergen, A.V.1
Boles, N.C.2
Goodell, M.A.3
-
14
-
-
79955530513
-
Chronic exposure to a TLR ligand injures hematopoietic stem cells
-
Esplin, B.L., Shimazu, T., Welner, R.S., Garrett, K.P., Nie, L., Zhang, Q., Humphrey, M.B., Yang, Q., Borghesi, L.A. & Kincade, P.W. (2011) Chronic exposure to a TLR ligand injures hematopoietic stem cells. J. Immunol. 186, 5367-5375.
-
(2011)
J. Immunol.
, vol.186
, pp. 5367-5375
-
-
Esplin, B.L.1
Shimazu, T.2
Welner, R.S.3
Garrett, K.P.4
Nie, L.5
Zhang, Q.6
Humphrey, M.B.7
Yang, Q.8
Borghesi, L.A.9
Kincade, P.W.10
-
15
-
-
66149115277
-
IFNα activates dormant haematopoietic stem cells in vivo
-
Essers, M.A., Offner, S., Blanco-Bose, W.E., Waibler, Z., Kalinke, U., Duchosal, M.A. & Trumpp, A. (2009) IFNα activates dormant haematopoietic stem cells in vivo. Nature 458, 904-908.
-
(2009)
Nature
, vol.458
, pp. 904-908
-
-
Essers, M.A.1
Offner, S.2
Blanco-Bose, W.E.3
Waibler, Z.4
Kalinke, U.5
Duchosal, M.A.6
Trumpp, A.7
-
17
-
-
53049092465
-
Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states
-
Hayashi, K., Lopes, S.M., Tang, F. & Surani, M.A. (2008) Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3, 391-401.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 391-401
-
-
Hayashi, K.1
Lopes, S.M.2
Tang, F.3
Surani, M.A.4
-
18
-
-
79551610653
-
Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
-
Hochmuth, C.E., Biteau, B., Bohmann, D. & Jasper, H. (2011) Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Cell Stem Cell 8, 188-199.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 188-199
-
-
Hochmuth, C.E.1
Biteau, B.2
Bohmann, D.3
Jasper, H.4
-
19
-
-
84855453637
-
Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis
-
Hou, Y., Xue, P., Bai, Y., Liu, D., Woods, C.G., Yarborough, K., Fu, J., Zhang, Q., Sun, G., Collins, S., Chan, J.Y., Yamamoto, M., Andersen, M.E. & Pi, J. (2012) Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. Free Radic. Biol. Med. 52, 462-472.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 462-472
-
-
Hou, Y.1
Xue, P.2
Bai, Y.3
Liu, D.4
Woods, C.G.5
Yarborough, K.6
Fu, J.7
Zhang, Q.8
Sun, G.9
Collins, S.10
Chan, J.Y.11
Yamamoto, M.12
Andersen, M.E.13
Pi, J.14
-
20
-
-
27744450995
-
Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema
-
Ishii, Y., Itoh, K., Morishima, Y., Kimura, T., Kiwamoto, T., Iizuka, T., Hegab, A.E., Hosoya, T., Nomura, A., Sakamoto, T., Yamamoto, M. & Sekizawa, K. (2005) Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema. J. Immunol. 175, 6968-6975.
-
(2005)
J. Immunol.
, vol.175
, pp. 6968-6975
-
-
Ishii, Y.1
Itoh, K.2
Morishima, Y.3
Kimura, T.4
Kiwamoto, T.5
Iizuka, T.6
Hegab, A.E.7
Hosoya, T.8
Nomura, A.9
Sakamoto, T.10
Yamamoto, M.11
Sekizawa, K.12
-
21
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
Ito, K., Hirao, A., Arai, F., Matsuoka, S., Takubo, K., Hamaguchi, I., Nomiyama, K., Hosokawa, K., Sakurada, K., Nakagata, N., Ikeda, Y., Mak, T.W. & Sudo, T. (2004) Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 431, 997-1002.
-
(2004)
Nature
, vol.431
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
Nomiyama, K.7
Hosokawa, K.8
Sakurada, K.9
Nakagata, N.10
Ikeda, Y.11
Mak, T.W.12
Sudo, T.13
-
22
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igrashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., Yamamoto, M. & Nabeshima, Y. (1997) An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236, 313-322.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igrashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.12
-
23
-
-
10744230015
-
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Δ(12,14)-prostaglandin j(2)
-
Itoh, K., Mochizuki, M., Ishii, Y., Shibata, T., Kawamoto, Y., Kelly, V., Sekizawa, K., Uchida, K. & Yamamoto, M. (2004) Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Δ(12, 14)-prostaglandin j(2). Mol. Cell. Biol. 24, 36-45.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 36-45
-
-
Itoh, K.1
Mochizuki, M.2
Ishii, Y.3
Shibata, T.4
Kawamoto, Y.5
Kelly, V.6
Sekizawa, K.7
Uchida, K.8
Yamamoto, M.9
-
24
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J.D. & Yamamoto, M. (1999) Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13, 76-86.
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
25
-
-
35548936968
-
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
-
Jang, Y.Y. & Sharkis, S.J. (2007) A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 110, 3056-3063.
-
(2007)
Blood
, vol.110
, pp. 3056-3063
-
-
Jang, Y.Y.1
Sharkis, S.J.2
-
26
-
-
78751691722
-
Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia
-
Kawatani, Y., Suzuki, T., Shimizu, R., Kelly, V.P. & Yamamoto, M. (2011) Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia. Blood 117, 986-996.
-
(2011)
Blood
, vol.117
, pp. 986-996
-
-
Kawatani, Y.1
Suzuki, T.2
Shimizu, R.3
Kelly, V.P.4
Yamamoto, M.5
-
27
-
-
84879344989
-
Roles Nrf2 plays in myeloid cells and related disorders
-
Kobayashi, E., Suzuki, T. & Yamamoto, M. (2013) Roles Nrf2 plays in myeloid cells and related disorders. Oxid. Med. Cell. Longev. 2013, 529219.
-
(2013)
Oxid. Med. Cell. Longev.
, vol.2013
, pp. 529219
-
-
Kobayashi, E.1
Suzuki, T.2
Yamamoto, M.3
-
28
-
-
0036668466
-
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
-
Kobayashi, M., Itoh, K., Suzuki, T., Osanai, H., Nishikawa, K., Katoh, Y., Takagi, Y. & Yamamoto, M. (2002) Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 7, 807-820.
-
(2002)
Genes Cells
, vol.7
, pp. 807-820
-
-
Kobayashi, M.1
Itoh, K.2
Suzuki, T.3
Osanai, H.4
Nishikawa, K.5
Katoh, Y.6
Takagi, Y.7
Yamamoto, M.8
-
29
-
-
58249117780
-
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds
-
Kobayashi, M., Li, L., Iwamoto, N., Nakajima-Takagi, Y., Kaneko, H., Nakayama, Y., Eguchi, M., Wada, Y., Kumagai, Y. & Yamamoto, M. (2009) The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol. Cell. Biol. 29, 493-502.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 493-502
-
-
Kobayashi, M.1
Li, L.2
Iwamoto, N.3
Nakajima-Takagi, Y.4
Kaneko, H.5
Nakayama, Y.6
Eguchi, M.7
Wada, Y.8
Kumagai, Y.9
Yamamoto, M.10
-
30
-
-
80054713581
-
Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis
-
Kong, X., Thimmulappa, R., Craciun, F., Harvey, C., Singh, A., Kombairaju, P., Reddy, S.P., Remick, D. & Biswal, S. (2011) Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis. Am. J. Respir. Crit. Care Med. 184, 928-938.
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.184
, pp. 928-938
-
-
Kong, X.1
Thimmulappa, R.2
Craciun, F.3
Harvey, C.4
Singh, A.5
Kombairaju, P.6
Reddy, S.P.7
Remick, D.8
Biswal, S.9
-
31
-
-
0029155706
-
Inducible gene targeting in mice
-
Kuhn, R., Schwenk, F., Aguet, M. & Rajewsky, K. (1995) Inducible gene targeting in mice. Science 269, 1427-1429.
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kuhn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
32
-
-
0035308590
-
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
-
Lee, E.C., Yu, D., Martinez de Velasco, J., Tessaroll, L., Swing, D.A., Court, D.L., Jenkins, N.A. & Copeland, N.G. (2001) A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73, 56-65.
-
(2001)
Genomics
, vol.73
, pp. 56-65
-
-
Lee, E.C.1
Yu, D.2
Martinez de Velasco, J.3
Tessaroll, L.4
Swing, D.A.5
Court, D.L.6
Jenkins, N.A.7
Copeland, N.G.8
-
33
-
-
34247092922
-
Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
-
Mansson, R., Hultquist, A., Luc, S., et al. (2007) Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26, 407-419.
-
(2007)
Immunity
, vol.26
, pp. 407-419
-
-
Mansson, R.1
Hultquist, A.2
Luc, S.3
-
34
-
-
84055177613
-
The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independent of ROS levels
-
Merchant, A.A., Singh, A., Matsui, W. & Biswal, S. (2011) The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independent of ROS levels. Blood 118, 6572-6579.
-
(2011)
Blood
, vol.118
, pp. 6572-6579
-
-
Merchant, A.A.1
Singh, A.2
Matsui, W.3
Biswal, S.4
-
35
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto, K., Araki, K.Y., Naka, K., et al. (2007) Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 1, 101-112.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
-
36
-
-
77449114227
-
NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation
-
Motohashi, H., Kimura, M., Fujita, R., Inoue, A., Pan, X., Takayama, M., Katsuoka, F., Aburatani, H., Bresnick, E.H. & Yamamoto, M. (2010) NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation. Blood 115, 677-686.
-
(2010)
Blood
, vol.115
, pp. 677-686
-
-
Motohashi, H.1
Kimura, M.2
Fujita, R.3
Inoue, A.4
Pan, X.5
Takayama, M.6
Katsuoka, F.7
Aburatani, H.8
Bresnick, E.H.9
Yamamoto, M.10
-
37
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress response mechanism
-
Motohashi, H. & Yamamoto, M. (2004) Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol. Med. 10, 549-557.
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
38
-
-
0036081059
-
Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S
-
Na Nakorn, T., Traver, D., Weissman, I.L. & Akashi, K. (2002) Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J. Clin. Invest. 109, 1579-1585.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1579-1585
-
-
Na Nakorn, T.1
Traver, D.2
Weissman, I.L.3
Akashi, K.4
-
39
-
-
64049102658
-
Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells
-
Ng, S.Y., Yoshida, T., Zhang, J. & Georgopoulos, K. (2009) Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells. Immunity 30, 493-507.
-
(2009)
Immunity
, vol.30
, pp. 493-507
-
-
Ng, S.Y.1
Yoshida, T.2
Zhang, J.3
Georgopoulos, K.4
-
40
-
-
28144445947
-
Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity
-
Okawa, H., Motohashi, H., Kobayashi, A., Aburatani, H., Kensler, T.W. & Yamamoto, M. (2006) Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. Biochem. Biophys. Res. Commun. 339, 79-88.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.339
, pp. 79-88
-
-
Okawa, H.1
Motohashi, H.2
Kobayashi, A.3
Aburatani, H.4
Kensler, T.W.5
Yamamoto, M.6
-
41
-
-
77950553993
-
Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity
-
Pi, J., Leung, L., Xue, P., Wang, W., Hou, Y., Liu, D., Yehuda-Shnaidman, E., Lee, C., Lau, J., Kurtz, T.W. & Chan, J.Y. (2010) Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J. Biol. Chem. 285, 9292-9300.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9292-9300
-
-
Pi, J.1
Leung, L.2
Xue, P.3
Wang, W.4
Hou, Y.5
Liu, D.6
Yehuda-Shnaidman, E.7
Lee, C.8
Lau, J.9
Kurtz, T.W.10
Chan, J.Y.11
-
42
-
-
84862778068
-
Inferring rules of lineage commitment in haematopoiesis
-
Pina, C., Fugazza, C., Tipping, A.J., Brown, J., Soneji, S., Peterson, C. & Enver, T. (2012) Inferring rules of lineage commitment in haematopoiesis. Nat. Cell Biol. 14, 287-294.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 287-294
-
-
Pina, C.1
Fugazza, C.2
Tipping, A.J.3
Brown, J.4
Soneji, S.5
Peterson, C.6
Enver, T.7
-
43
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in Nrf2 transcription factor-deficient mice
-
Ramos-Gomez, M., Kwak, M.K., Dolan, P.M., Itoh, K., Yamamoto, M., Talalay, P. & Kensler, T.W. (2001) Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in Nrf2 transcription factor-deficient mice. Proc. Natl Acad. Sci. USA 98, 3410-3415.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
Kensler, T.W.7
-
44
-
-
18244386712
-
Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2
-
Sakurai, A., Nishimoto, M., Himeno, S., Imura, N., Tsujimoto, M., Kunimoto, M. & Hara, S. (2005) Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2. J. Cell. Physiol. 203, 529-537.
-
(2005)
J. Cell. Physiol.
, vol.203
, pp. 529-537
-
-
Sakurai, A.1
Nishimoto, M.2
Himeno, S.3
Imura, N.4
Tsujimoto, M.5
Kunimoto, M.6
Hara, S.7
-
45
-
-
84885634008
-
Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
-
Sanjuan-Pla, A., Macaulay, I.C., Jensen, C.T., et al. (2013) Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy. Nature 502, 232-236.
-
(2013)
Nature
, vol.502
, pp. 232-236
-
-
Sanjuan-Pla, A.1
Macaulay, I.C.2
Jensen, C.T.3
-
46
-
-
84856951081
-
Reactive oxygen species: are they important for haematopoietisis?
-
Sardina, J.L., Lopez-Ruano, G., Sanchez-Sanchez, B., Llanillo, M. & Hernandez-Hernandez, A. (2012) Reactive oxygen species: are they important for haematopoietisis? Crit. Rev. Oncol. Hematol. 81, 257-274.
-
(2012)
Crit. Rev. Oncol. Hematol.
, vol.81
, pp. 257-274
-
-
Sardina, J.L.1
Lopez-Ruano, G.2
Sanchez-Sanchez, B.3
Llanillo, M.4
Hernandez-Hernandez, A.5
-
47
-
-
84859181084
-
Demand-adapted regulation of early hematopoiesis in infection and inflammation
-
Takizawa, H., Boettcher, S. & Manz, M.G. (2012) Demand-adapted regulation of early hematopoiesis in infection and inflammation. Blood 119, 2991-3002.
-
(2012)
Blood
, vol.119
, pp. 2991-3002
-
-
Takizawa, H.1
Boettcher, S.2
Manz, M.G.3
-
48
-
-
33645530745
-
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
-
Thimmulappa, R.K., Lee, H., Rangasamy, T., Reddy, S.P., Yamamoto, M., Kensler, T.W. & Biswal, S. (2006) Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J. Clin. Invest. 116, 984-995.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 984-995
-
-
Thimmulappa, R.K.1
Lee, H.2
Rangasamy, T.3
Reddy, S.P.4
Yamamoto, M.5
Kensler, T.W.6
Biswal, S.7
-
49
-
-
84874655208
-
Nrf2 regulates haematopoietic stem cell function
-
Tsai, J.J., Dudakov, J.A., Takahashi, K., et al. (2013) Nrf2 regulates haematopoietic stem cell function. Nat. Cell Biol. 15, 309-316.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 309-316
-
-
Tsai, J.J.1
Dudakov, J.A.2
Takahashi, K.3
-
50
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi, N., Itoh, K., Wakabayashi, J., Motohashi, H., Noda, S., Takahashi, S., Imakado, S., Kotsuji, T., Otuka, F., Roop, D.R., Harada, T., Engel, J.D. & Yamamoto, M. (2003) Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat. Genet. 35, 238-245.
-
(2003)
Nat. Genet.
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
Imakado, S.7
Kotsuji, T.8
Otuka, F.9
Roop, D.R.10
Harada, T.11
Engel, J.D.12
Yamamoto, M.13
-
51
-
-
77956640097
-
Regulation of notch1 signaling by nrf2: implications for tissue regeneration
-
Wakabayashi, N., Shin, S., Slocum, S.L., Agoston, E.S., Wakabayashi, J., Kwak, M.K., Misra, V., Biswal, S., Yamamoto, M. & Kensler, T.W. (2010) Regulation of notch1 signaling by nrf2: implications for tissue regeneration. Sci. Signal. 3, ra52.
-
(2010)
Sci. Signal.
, vol.3
-
-
Wakabayashi, N.1
Shin, S.2
Slocum, S.L.3
Agoston, E.S.4
Wakabayashi, J.5
Kwak, M.K.6
Misra, V.7
Biswal, S.8
Yamamoto, M.9
Kensler, T.W.10
-
52
-
-
84856808208
-
Embryonic lethality and fetal liver apoptosis in mice lacking all three small Maf proteins
-
Yamazaki, H., Katsuoka, F., Motohashi, H., Engel, J.D. & Yamamoto, M. (2012) Embryonic lethality and fetal liver apoptosis in mice lacking all three small Maf proteins. Mol. Cell. Biol. 32, 808-816.
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 808-816
-
-
Yamazaki, H.1
Katsuoka, F.2
Motohashi, H.3
Engel, J.D.4
Yamamoto, M.5
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