Regulation of cullin ring e3 ubiquitin ligases by cand1 in vivo

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Chua, Yee Shin ^a   Boh, Boon Kim ^a,b   Ponyeam, Wanpen ^a   Hagen, Thilo ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CULLIN; CULLIN RING LIGASE; F BOX PROTEIN; PROTEIN CAND1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CAND1 PROTEIN, HUMAN; MULTIPROTEIN COMPLEX; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENZYME REGULATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR MECHANICS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; UBIQUITINATION; CELL LINE; CHEMICAL MODEL; METABOLISM; PHYSIOLOGY;

MAMMALIA;

CELL LINE; CULLIN PROTEINS; HUMANS; MODELS, CHEMICAL; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; TRANSCRIPTION FACTORS; UBIQUITINATION;

EID: 79251589622     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016071     Document Type: Article

References (25)

1. Petroski MD, Deshaies RJ (2005) Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6: 9-20.
2. Bosu DR, Kipreos ET (2008) Cullin-RING ubiquitin ligases: global regulation and activation cycles. Cell division 3: 7.
3. Lyapina S, Cope G, Shevchenko A, Serino G, Tsuge T, et al. (2001) Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science 292: 1382-1385.
4. Cope GA, Suh GS, Aravind L, Schwarz SE, Zipursky SL, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298: 608-611.
5. Liu J, Furukawa M, Matsumoto T, Xiong Y (2002) NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases. Mol Cell 10: 1511-1518.
6. Zheng J, Yang X, Harrell JM, Ryzhikov S, Shim EH, et al. (2002) CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex. Mol Cell 10: 1519-1526.
7. Min KW, Hwang JW, Lee JS, Park Y, Tamura TA, et al. (2003) TIP120A associates with cullins and modulates ubiquitin ligase activity. J Biol Chem 278: 15905-15910.
8. Oshikawa K, Matsumoto M, Yada M, Kamura T, Hatakeyama S, et al. (2003) Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1. Biochem Biophys Res Commun 303: 1209-1216.
9. Chuang HW, Zhang W, Gray WM (2004) Arabidopsis ETA2, an apparent ortholog of the human cullin-interacting protein CAND1, is required for auxin responses mediated by the SCF(TIR1) ubiquitin ligase. Plant Cell 16: 1883-1897.
10. Feng S, Shen Y, Sullivan JA, Rubio V, Xiong Y, et al. (2004) Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation. Plant Cell 16: 1870-1882.
11. Cheng Y, Dai X, Zhao Y (2004) AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis. Plant Physiol 135: 1020-1026.
12. Bosu DR, Feng H, Min K, Kim Y, Wallenfang MR et al (2010) C. elegans CAND1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues. Dev Biol 346: 113-126.
13. Chew EH, Poobalasingam T, Hawkey CJ, Hagen T (2007) Characterization of cullin-based E3 ubiquitin ligases in intact mammalian cells-evidence for cullin dimerization. Cell Signal 19: 1071-1080.
14. Lo SC, Hannink M (2006) CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1. Mol Cell Biol 26: 1235-1244.
15. Schmidt MW, McQuary PR, Wee S, Hofmann K, Wolf DA (2009) F-boxdirected CRL complex assembly and regulation by the CSN and CAND1. Mol Cell 35: 586-597.
16. Chew EH, Hagen T (2007) Substrate-mediated regulation of cullin neddylation. J Biol Chem 282: 17032-17040.
17. Culbert AA, Brown MJ, Frame S, Hagen T, Cross DA, et al. (2001) GSK-3 inhibition by adenoviral FRAT1 overexpression is neuroprotective and induces Tau dephosphorylation and beta-catenin stabilisation without elevation of glycogen synthase activity. FEBS Lett 507: 288-294.
18. Goldenberg SJ, Cascio TC, Shumway SD, Garbutt KC, Liu J, et al. (2004) Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases. Cell 119: 517-528.
19. Mathias N, Johnson SL, Winey M, Adams AE, Goetsch L, et al. (1996) Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins. Mol Cell Biol 16: 6634-6643.
20. Lammer D, Mathias N, Laplaza JM, Jiang W, Liu Y, et al. (1998) Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev 12: 914-926.
21. Patton EE, Willems AR, Sa D, Kuras L, Thomas D, et al. (1998) Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes Dev 12: 692-705.
22. Wada H, Yeh ET, Kamitani T (2000) A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo. J Biol Chem 275: 17008-17015.
23. Bornstein G, Ganoth D, Hershko A (2006) Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate. Proc Natl Acad Sci USA 103: 11515-11520.
24. Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, et al. (2002) Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature 416: 703-709.
25. Min KW, Kwon MJ, Park HS, Park Y, Yoon SK, et al. (2005) CAND1 enhances deneddylation of CUL1 by COP9 signalosome. Biochem Biophys Res Commun 334: 867-874.