-
1
-
-
52449104809
-
DNA vaccines: Ready for prime time?
-
M.A. Kutzler, and D.B. Weiner DNA vaccines: ready for prime time? Nat. Rev. Genet. 9 2008 776 788 10.1038/nrg2432
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 776-788
-
-
Kutzler, M.A.1
Weiner, D.B.2
-
2
-
-
60149088848
-
Origins and mechanisms of miRNAs and siRNAs
-
R.W. Carthew, and E.J. Sontheimer Origins and mechanisms of miRNAs and siRNAs Cell 136 2009 642 655 10.1016/j.cell.2009.01.035
-
(2009)
Cell
, vol.136
, pp. 642-655
-
-
Carthew, R.W.1
Sontheimer, E.J.2
-
3
-
-
84923106217
-
Therapeutic genome editing: Prospects and challenges
-
D.B.T. Cox, R.J. Platt, and F. Zhang Therapeutic genome editing: prospects and challenges Nat. Med. 21 2015 121 131 10.1038/nm.3793
-
(2015)
Nat. Med.
, vol.21
, pp. 121-131
-
-
Cox, D.B.T.1
Platt, R.J.2
Zhang, F.3
-
4
-
-
84934307590
-
Knocking down disease: A progress report on siRNA therapeutics
-
A. Wittrup, and J. Lieberman Knocking down disease: a progress report on siRNA therapeutics Nat. Rev. Genet. 16 2015 543 552 10.1038/nrg3978
-
(2015)
Nat. Rev. Genet.
, vol.16
, pp. 543-552
-
-
Wittrup, A.1
Lieberman, J.2
-
5
-
-
84905503012
-
Therapeutic targeting of microRNAs: Current status and future challenges
-
Z. Li, and T.M. Rana Therapeutic targeting of microRNAs: current status and future challenges Nat. Rev. Drug Discov. 13 2014 622 638 10.1038/nrd4359
-
(2014)
Nat. Rev. Drug Discov.
, vol.13
, pp. 622-638
-
-
Li, Z.1
Rana, T.M.2
-
7
-
-
84922273505
-
In vivo delivery of miRNAs for cancer therapy: Challenges and strategies
-
Y. Chen, D. Gao, and L. Huang In vivo delivery of miRNAs for cancer therapy: challenges and strategies Adv. Drug Deliv. Rev. 81 2015 128 141 10.1016/j.addr.2014.05.009
-
(2015)
Adv. Drug Deliv. Rev.
, vol.81
, pp. 128-141
-
-
Chen, Y.1
Gao, D.2
Huang, L.3
-
8
-
-
33645148088
-
The silent treatment: SiRNAs as small molecule drugs
-
D.M. Dykxhoorn, D. Palliser, and J. Lieberman The silent treatment: siRNAs as small molecule drugs Gene Ther. 13 2006 541 552 10.1038/sj.gt.3302703
-
(2006)
Gene Ther.
, vol.13
, pp. 541-552
-
-
Dykxhoorn, D.M.1
Palliser, D.2
Lieberman, J.3
-
10
-
-
79951849229
-
RNA interference therapy in lung transplant patients infected with respiratory syncytial virus
-
M.R. Zamora, M. Budev, M. Rolfe, J. Gottlieb, A. Humar, J. DeVincenzo, and et al. RNA interference therapy in lung transplant patients infected with respiratory syncytial virus Am. J. Respir. Crit. Care Med. 183 2011 531 538 10.1164/rccm.201003-0422OC
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
, pp. 531-538
-
-
Zamora, M.R.1
Budev, M.2
Rolfe, M.3
Gottlieb, J.4
Humar, A.5
DeVincenzo, J.6
-
12
-
-
77952744763
-
Formulation strategy and use of excipients in pulmonary drug delivery
-
G. Pilcer, and K. Amighi Formulation strategy and use of excipients in pulmonary drug delivery Int. J. Pharm. 392 2010 1 19 10.1016/j.ijpharm.2010.03.017
-
(2010)
Int. J. Pharm.
, vol.392
, pp. 1-19
-
-
Pilcer, G.1
Amighi, K.2
-
13
-
-
33846849237
-
Phenotypic heterogeneity of the endothelium: II. Representative vascular beds
-
W.C. Aird Phenotypic heterogeneity of the endothelium: II. Representative vascular beds Circ. Res. 100 2007 174 190 10.1161/01.RES.0000255690.03436.ae
-
(2007)
Circ. Res.
, vol.100
, pp. 174-190
-
-
Aird, W.C.1
-
14
-
-
84869401515
-
Anomalous pulmonary venous connections
-
R. Katre, S.K. Burns, H. Murillo, M.J. Lane, and C.S. Restrepo Anomalous pulmonary venous connections Semin. Ultrasound, CT MRI 33 2012 485 499 10.1053/j.sult.2012.07.001
-
(2012)
Semin. Ultrasound, CT MRI
, vol.33
, pp. 485-499
-
-
Katre, R.1
Burns, S.K.2
Murillo, H.3
Lane, M.J.4
Restrepo, C.S.5
-
15
-
-
0344513087
-
Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
-
N.R. Labiris, and M.B. Dolovich Pulmonary drug delivery. Part I: physiological factors affecting therapeutic effectiveness of aerosolized medications Br. J. Clin. Pharmacol. 56 2003 588 599 10.1046/j.1365-2125.2003.01892.x
-
(2003)
Br. J. Clin. Pharmacol.
, vol.56
, pp. 588-599
-
-
Labiris, N.R.1
Dolovich, M.B.2
-
16
-
-
84867072460
-
Pulmonary vaccine delivery: A realistic approach?
-
W.F. Tonnis, G.F. Kersten, H.W. Frijlink, W.L.J. Hinrichs, A.H. de Boer, and J.-P. Amorij Pulmonary vaccine delivery: a realistic approach? J. Aerosol Med. Pulm. Drug Deliv. 25 2012 249 260 10.1089/jamp.2011.0931
-
(2012)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.25
, pp. 249-260
-
-
Tonnis, W.F.1
Kersten, G.F.2
Frijlink, H.W.3
Hinrichs, W.L.J.4
De Boer, A.H.5
Amorij, J.-P.6
-
17
-
-
0026604702
-
Functions of proteins and lipids in airway secretions
-
J. Jacquot, A. Hayem, and C. Galabert Functions of proteins and lipids in airway secretions Eur. Respir. J. 5 1992 343 358
-
(1992)
Eur. Respir. J.
, vol.5
, pp. 343-358
-
-
Jacquot, J.1
Hayem, A.2
Galabert, C.3
-
18
-
-
0025072154
-
Pulmonary metabolism of foreign compounds: Its role in metabolic activation
-
G.M. Cohen Pulmonary metabolism of foreign compounds: its role in metabolic activation Environ. Health Perspect. 85 1990 31 41 10.2307/3430663
-
(1990)
Environ. Health Perspect.
, vol.85
, pp. 31-41
-
-
Cohen, G.M.1
-
19
-
-
84904860154
-
Non-small-cell lung cancers: A heterogeneous set of diseases
-
Z. Chen, C.M. Fillmore, P.S. Hammerman, C.F. Kim, and K.-K. Wong Non-small-cell lung cancers: a heterogeneous set of diseases Nat. Rev. Cancer 14 2014 535 546 10.1038/nrc3775
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 535-546
-
-
Chen, Z.1
Fillmore, C.M.2
Hammerman, P.S.3
Kim, C.F.4
Wong, K.-K.5
-
21
-
-
84863011775
-
Roles of AKT1 and AKT2 in non-small cell lung cancer cell survival, growth, and migration
-
M.W. Lee, D.S. Kim, J.H. Lee, B.S. Lee, S.H. Lee, H.L. Jung, and et al. Roles of AKT1 and AKT2 in non-small cell lung cancer cell survival, growth, and migration Cancer Sci. 102 2011 1822 1828 10.1111/j.1349-7006.2011.02025.x
-
(2011)
Cancer Sci.
, vol.102
, pp. 1822-1828
-
-
Lee, M.W.1
Kim, D.S.2
Lee, J.H.3
Lee, B.S.4
Lee, S.H.5
Jung, H.L.6
-
22
-
-
80054697358
-
Aerosol delivery of spermine-based poly(amino ester)/Akt1 shRNA complexes for lung cancer gene therapy
-
H.-L.L. Jiang, S.-H.H. Hong, Y.-K.K. Kim, M.A. Islam, H.-J.J. Kim, Y.-J.J. Choi, and et al. Aerosol delivery of spermine-based poly(amino ester)/Akt1 shRNA complexes for lung cancer gene therapy Int. J. Pharm. 420 2011 256 265 10.1016/j.ijpharm.2011.08.045
-
(2011)
Int. J. Pharm.
, vol.420
, pp. 256-265
-
-
Jiang, H.-L.L.1
Hong, S.-H.H.2
Kim, Y.-K.K.3
Islam, M.A.4
Kim, H.-J.J.5
Choi, Y.-J.J.6
-
23
-
-
84866749143
-
Suppression of lung cancer progression by biocompatible glycerol triacrylate-spermine-mediated delivery of shAkt1
-
H.-L. Jiang, K. Hong, S. Kim, C.-S. Cho, and et al. Suppression of lung cancer progression by biocompatible glycerol triacrylate-spermine-mediated delivery of shAkt1 Int. J. Nanomedicine 7 2012 2293 10.2147/IJN.S29152
-
(2012)
Int. J. Nanomedicine
, vol.7
, pp. 2293
-
-
Jiang, H.-L.1
Hong, K.2
Kim, S.3
Cho, C.-S.4
-
24
-
-
84878415381
-
Lentivirus-AIMP2-DX2 shRNA suppresses cell proliferation by regulating Akt1 signaling pathway in the lungs of AIMP2(+)/(-) mice
-
S.-K. Hwang, S.-H. Chang, A. Minai-Tehrani, Y.-S. Kim, and M.-H. Cho Lentivirus-AIMP2-DX2 shRNA suppresses cell proliferation by regulating Akt1 signaling pathway in the lungs of AIMP2(+)/(-) mice J. Aerosol Med. Pulm. Drug Deliv. 26 2013 165 173 10.1089/jamp.2011.0959
-
(2013)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.26
, pp. 165-173
-
-
Hwang, S.-K.1
Chang, S.-H.2
Minai-Tehrani, A.3
Kim, Y.-S.4
Cho, M.-H.5
-
25
-
-
46349111796
-
Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis
-
C.-X. Xu, D. Jere, H. Jin, S.-H. Chang, Y.-S. Chung, J.-Y. Shin, and et al. Poly(ester amine)-mediated, aerosol-delivered Akt1 small interfering RNA suppresses lung tumorigenesis Am. J. Respir. Crit. Care Med. 178 2008 60 73 10.1164/rccm.200707-1022OC
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, pp. 60-73
-
-
Xu, C.-X.1
Jere, D.2
Jin, H.3
Chang, S.-H.4
Chung, Y.-S.5
Shin, J.-Y.6
-
26
-
-
40949100345
-
Poly(beta-amino ester) as a carrier for si/shRNA delivery in lung cancer cells
-
D. Jere, C.-X. Xu, R. Arote, C.-H. Yun, M.-H. Cho, and C.-S. Cho Poly(beta-amino ester) as a carrier for si/shRNA delivery in lung cancer cells Biomaterials 29 2008 2535 2547 10.1016/j.biomaterials.2008.02.018
-
(2008)
Biomaterials
, vol.29
, pp. 2535-2547
-
-
Jere, D.1
Xu, C.-X.2
Arote, R.3
Yun, C.-H.4
Cho, M.-H.5
Cho, C.-S.6
-
27
-
-
84878661078
-
Always cleave up your mess: Targeting collagen degradation to treat tissue fibrosis
-
W. McKleroy, T.-H. Lee, and K. Atabai Always cleave up your mess: targeting collagen degradation to treat tissue fibrosis AJP Lung Cell. Mol. Physiol. 304 2013 L709 L721 10.1152/ajplung.00418.2012
-
(2013)
AJP Lung Cell. Mol. Physiol.
, vol.304
, pp. L709-L721
-
-
McKleroy, W.1
Lee, T.-H.2
Atabai, K.3
-
28
-
-
0033830350
-
TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?
-
M. Selman, V. Ruiz, S. Cabrera, L. Segura, R. Ramírez, R. Barrios, and et al. TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment? Am. J. Physiol. Lung Cell. Mol. Physiol. 279 2000 L562 L574
-
(2000)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.279
, pp. L562-L574
-
-
Selman, M.1
Ruiz, V.2
Cabrera, S.3
Segura, L.4
Ramírez, R.5
Barrios, R.6
-
29
-
-
79960189227
-
Metalloproteinases in idiopathic pulmonary fibrosis
-
R.C.A. Dancer, A.M. Wood, and D.R. Thickett Metalloproteinases in idiopathic pulmonary fibrosis Eur. Respir. J. 38 2011 1461 1467 10.1183/09031936.00024711
-
(2011)
Eur. Respir. J.
, vol.38
, pp. 1461-1467
-
-
Dancer, R.C.A.1
Wood, A.M.2
Thickett, D.R.3
-
30
-
-
41749124757
-
The pathology of influenza virus infections
-
J.K. Taubenberger, and D.M. Morens The pathology of influenza virus infections Annu. Rev. Pathol. Mech. Dis. 3 2008 499 522 10.1146/annurev.pathmechdis.3.121806.154316
-
(2008)
Annu. Rev. Pathol. Mech. Dis.
, vol.3
, pp. 499-522
-
-
Taubenberger, J.K.1
Morens, D.M.2
-
31
-
-
33750071716
-
Emerging respiratory viruses: Challenges and vaccine strategies
-
L. Gillim-Ross, and K. Subbarao Emerging respiratory viruses: challenges and vaccine strategies Clin. Microbiol. Rev. 19 2006 614 636 10.1128/CMR.00005-06
-
(2006)
Clin. Microbiol. Rev.
, vol.19
, pp. 614-636
-
-
Gillim-Ross, L.1
Subbarao, K.2
-
32
-
-
0037418322
-
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
-
Q. Ge, M.T. McManus, T. Nguyen, C.-H. Shen, P.A. Sharp, H.N. Eisen, and et al. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription Proc. Natl. Acad. Sci. 100 2003 2718 2723 10.1073/pnas.0437841100
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 2718-2723
-
-
Ge, Q.1
McManus, M.T.2
Nguyen, T.3
Shen, C.-H.4
Sharp, P.A.5
Eisen, H.N.6
-
33
-
-
2942620143
-
Protection against lethal influenza virus challenge by RNA interference in vivo
-
S.M. Tompkins, C.-Y. Lo, T.M. Tumpey, and S.L. Epstein Protection against lethal influenza virus challenge by RNA interference in vivo Proc. Natl. Acad. Sci. U. S. A. 101 2004 8682 8686 10.1073/pnas.0402630101
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 8682-8686
-
-
Tompkins, S.M.1
Lo, C.-Y.2
Tumpey, T.M.3
Epstein, S.L.4
-
34
-
-
14544277094
-
Dry powder inhalers for pulmonary drug delivery
-
H.W. Frijlink, and A.H. De Boer Dry powder inhalers for pulmonary drug delivery Expert Opin. Drug Deliv. 1 2004 67 86 10.1517/17425247.1.1.67
-
(2004)
Expert Opin. Drug Deliv.
, vol.1
, pp. 67-86
-
-
Frijlink, H.W.1
De Boer, A.H.2
-
35
-
-
79951577062
-
Influence of particle size on regional lung deposition - What evidence is there?
-
T.C. Carvalho, J.I. Peters, and R.O. Williams III Influence of particle size on regional lung deposition - what evidence is there? Int. J. Pharm. 406 2011 1 10 10.1016/j.ijpharm.2010.12.040
-
(2011)
Int. J. Pharm.
, vol.406
, pp. 1-10
-
-
Carvalho, T.C.1
Peters, J.I.2
Williams, R.O.3
-
36
-
-
84908235237
-
Technological and practical challenges of dry powder inhalers and formulations
-
M. Hoppentocht, P. Hagedoorn, H.W. Frijlink, and A.H. de Boer Technological and practical challenges of dry powder inhalers and formulations Adv. Drug Deliv. Rev. 75 2014 18 31 10.1016/j.addr.2014.04.004
-
(2014)
Adv. Drug Deliv. Rev.
, vol.75
, pp. 18-31
-
-
Hoppentocht, M.1
Hagedoorn, P.2
Frijlink, H.W.3
De Boer, A.H.4
-
37
-
-
84906322938
-
The clinical relevance of dry powder inhaler performance for drug delivery
-
P. Demoly, P. Hagedoorn, A.H. de Boer, and H.W. Frijlink The clinical relevance of dry powder inhaler performance for drug delivery Respir. Med. 108 2014 1195 1203 10.1016/j.rmed.2014.05.009
-
(2014)
Respir. Med.
, vol.108
, pp. 1195-1203
-
-
Demoly, P.1
Hagedoorn, P.2
De Boer, A.H.3
Frijlink, H.W.4
-
39
-
-
84896911109
-
Cellular uptake and intracellular trafficking of oligonucleotides: Implications for oligonucleotide pharmacology
-
R.L. Juliano, X. Ming, K. Carver, and B. Laing Cellular uptake and intracellular trafficking of oligonucleotides: implications for oligonucleotide pharmacology Nucleic Acid Ther. 24 2014 101 113 10.1089/nat.2013.0463
-
(2014)
Nucleic Acid Ther.
, vol.24
, pp. 101-113
-
-
Juliano, R.L.1
Ming, X.2
Carver, K.3
Laing, B.4
-
41
-
-
84880304273
-
Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape
-
J. Gilleron, W. Querbes, A. Zeigerer, A. Borodovsky, G. Marsico, U. Schubert, and et al. Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape Nat. Biotechnol. 31 2013 638 646 10.1038/nbt.2612
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 638-646
-
-
Gilleron, J.1
Querbes, W.2
Zeigerer, A.3
Borodovsky, A.4
Marsico, G.5
Schubert, U.6
-
42
-
-
34247205938
-
Pulmonary vaccine delivery
-
D. Lu, and A.J. Hickey Pulmonary vaccine delivery Expert Rev. Vaccines. 6 2007 213 226 10.1586/14760584.6.2.213
-
(2007)
Expert Rev. Vaccines.
, vol.6
, pp. 213-226
-
-
Lu, D.1
Hickey, A.J.2
-
43
-
-
84884538716
-
Devices and formulations for pulmonary vaccination
-
W.F. Tonnis, A.J. Lexmond, H.W. Frijlink, A.H. de Boer, and W.L. Hinrichs Devices and formulations for pulmonary vaccination Expert Opin. Drug Deliv. 10 2013 1383 1397 10.1517/17425247.2013.810622
-
(2013)
Expert Opin. Drug Deliv.
, vol.10
, pp. 1383-1397
-
-
Tonnis, W.F.1
Lexmond, A.J.2
Frijlink, H.W.3
De Boer, A.H.4
Hinrichs, W.L.5
-
44
-
-
21744459706
-
Trends in the technology-driven development of new inhalation devices
-
H.W. Frijlink, and A.H. de Boer Trends in the technology-driven development of new inhalation devices Drug Discov. Today Technol. 2 2005 47 57 10.1016/j.ddtec.2005.05.020
-
(2005)
Drug Discov. Today Technol.
, vol.2
, pp. 47-57
-
-
Frijlink, H.W.1
De Boer, A.H.2
-
45
-
-
50249123944
-
Targeted drug-aerosol delivery in the human respiratory system
-
C. Kleinstreuer, Z. Zhang, and J.F. Donohue Targeted drug-aerosol delivery in the human respiratory system Annu. Rev. Biomed. Eng. 10 2008 195 220 10.1146/annurev.bioeng.10.061807.160544
-
(2008)
Annu. Rev. Biomed. Eng.
, vol.10
, pp. 195-220
-
-
Kleinstreuer, C.1
Zhang, Z.2
Donohue, J.F.3
-
46
-
-
79952705824
-
New developments in dry powder pulmonary vaccine delivery
-
T. Sou, E.N. Meeusen, M. de Veer, D.A.V. Morton, L.M. Kaminskas, and M.P. McIntosh New developments in dry powder pulmonary vaccine delivery Trends Biotechnol. 29 2011 191 198 10.1016/j.tibtech.2010.12.009
-
(2011)
Trends Biotechnol.
, vol.29
, pp. 191-198
-
-
Sou, T.1
Meeusen, E.N.2
De Veer, M.3
Morton, D.A.V.4
Kaminskas, L.M.5
McIntosh, M.P.6
-
47
-
-
84886608162
-
Comment on: Devices and formulations for pulmonary vaccination
-
R. Hatley, and J. Pritchard Comment on: Devices and formulations for pulmonary vaccination Expert Opin. Drug Deliv. 10 2013 1593 1595 10.1517/17425247.2013.833181
-
(2013)
Expert Opin. Drug Deliv.
, vol.10
, pp. 1593-1595
-
-
Hatley, R.1
Pritchard, J.2
-
48
-
-
84947747408
-
Dry powder formulation of plasmid DNA and siRNA for inhalation
-
M. Chow, and J. Lam Dry powder formulation of plasmid DNA and siRNA for inhalation Curr. Pharm. Des. 21 2015 3854 3866 10.2174/1381612821666150820105916
-
(2015)
Curr. Pharm. Des.
, vol.21
, pp. 3854-3866
-
-
Chow, M.1
Lam, J.2
-
49
-
-
84907973364
-
Vector platforms for gene therapy of inherited retinopathies
-
I. Trapani, A. Puppo, and A. Auricchio Vector platforms for gene therapy of inherited retinopathies Prog. Retin. Eye Res. 43 2014 108 128 10.1016/j.preteyeres.2014.08.001
-
(2014)
Prog. Retin. Eye Res.
, vol.43
, pp. 108-128
-
-
Trapani, I.1
Puppo, A.2
Auricchio, A.3
-
50
-
-
68649111166
-
Adeno-associated virus vector integration
-
D.R. Deyle, and D.W. Russell Adeno-associated virus vector integration Curr. Opin. Mol. Ther. 11 2009 442 447
-
(2009)
Curr. Opin. Mol. Ther.
, vol.11
, pp. 442-447
-
-
Deyle, D.R.1
Russell, D.W.2
-
51
-
-
34447535345
-
Engineering targeted viral vectors for gene therapy
-
R. Waehler, S.J. Russell, and D.T. Curiel Engineering targeted viral vectors for gene therapy Nat. Rev. Genet. 8 2007 573 587 10.1038/nrg2141
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 573-587
-
-
Waehler, R.1
Russell, S.J.2
Curiel, D.T.3
-
53
-
-
58749104364
-
The promises and pitfalls of RNA-interference-based therapeutics
-
D. Castanotto, and J.J. Rossi The promises and pitfalls of RNA-interference-based therapeutics Nature 457 2009 426 433 10.1038/nature07758
-
(2009)
Nature
, vol.457
, pp. 426-433
-
-
Castanotto, D.1
Rossi, J.J.2
-
54
-
-
84858745568
-
Physicochemical characterization techniques for lipid based delivery systems for siRNA
-
M. Kapoor, D.J. Burgess, and S.D. Patil Physicochemical characterization techniques for lipid based delivery systems for siRNA Int. J. Pharm. 427 2012 35 57 10.1016/j.ijpharm.2011.09.032
-
(2012)
Int. J. Pharm.
, vol.427
, pp. 35-57
-
-
Kapoor, M.1
Burgess, D.J.2
Patil, S.D.3
-
55
-
-
84863928267
-
Nonviral Pulmonary Delivery of siRNA
-
O.M. Merkel, and T. Kissel Nonviral Pulmonary Delivery of siRNA Acc. Chem. Res. 45 2012 961 970 10.1021/ar200110p
-
(2012)
Acc. Chem. Res.
, vol.45
, pp. 961-970
-
-
Merkel, O.M.1
Kissel, T.2
-
56
-
-
84904544984
-
Non-viral vectors for gene-based therapy
-
H. Yin, R.L. Kanasty, A.A. Eltoukhy, A.J. Vegas, J.R. Dorkin, and D.G. Anderson Non-viral vectors for gene-based therapy Nat. Rev. Genet. 15 2014 541 555 10.1038/nrg3763
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 541-555
-
-
Yin, H.1
Kanasty, R.L.2
Eltoukhy, A.A.3
Vegas, A.J.4
Dorkin, J.R.5
Anderson, D.G.6
-
57
-
-
84871153649
-
Chitosan-coated PLGA nanoparticles: A sustained drug release strategy for cell cultures
-
L. Chronopoulou, M. Massimi, M.F. Giardi, C. Cametti, L.C. Devirgiliis, M. Dentini, and et al. Chitosan-coated PLGA nanoparticles: a sustained drug release strategy for cell cultures Colloids Surfaces B Biointerfaces. 103 2013 310 317 10.1016/j.colsurfb.2012.10.063
-
(2013)
Colloids Surfaces B Biointerfaces.
, vol.103
, pp. 310-317
-
-
Chronopoulou, L.1
Massimi, M.2
Giardi, M.F.3
Cametti, C.4
Devirgiliis, L.C.5
Dentini, M.6
-
58
-
-
60149103022
-
Extracellular barriers in respiratory gene therapy
-
N. Sanders, C. Rudolph, K. Braeckmans, S.C. De Smedt, and J. Demeester Extracellular barriers in respiratory gene therapy Adv. Drug Deliv. Rev. 61 2009 115 127 10.1016/j.addr.2008.09.011
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 115-127
-
-
Sanders, N.1
Rudolph, C.2
Braeckmans, K.3
De Smedt, S.C.4
Demeester, J.5
-
59
-
-
67651172938
-
Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis
-
A.G. Rosas-Taraco, D.M. Higgins, J. Sánchez-Campillo, E.J. Lee, I.M. Orme, M. González-Juarrero, and et al. Intrapulmonary delivery of XCL1-targeting small interfering RNA in mice chronically infected with Mycobacterium tuberculosis Am. J. Respir. Cell Mol. Biol. 41 2009 136 145 10.1165/rcmb.2008-0363OC
-
(2009)
Am. J. Respir. Cell Mol. Biol.
, vol.41
, pp. 136-145
-
-
Rosas-Taraco, A.G.1
Higgins, D.M.2
Sánchez-Campillo, J.3
Lee, E.J.4
Orme, I.M.5
González-Juarrero, M.6
-
60
-
-
82955233645
-
Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense
-
S. Moschos, M. Frick, B. Taylor, P. Turnpenny, H. Graves, K.G. Spink, and et al. Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense Mol. Ther. 19 2011 2163 2168 10.1038/mt.2011.206
-
(2011)
Mol. Ther.
, vol.19
, pp. 2163-2168
-
-
Moschos, S.1
Frick, M.2
Taylor, B.3
Turnpenny, P.4
Graves, H.5
Spink, K.G.6
-
61
-
-
77958149807
-
Decreased level of PDCD4 (programmed cell death 4) protein activated cell proliferation in the lung of A/J mouse
-
S.-K. Hwang, A. Minai-Tehrani, H.-T. Lim, J.-Y. Shin, G.-H. An, K.-H. Lee, and et al. Decreased level of PDCD4 (programmed cell death 4) protein activated cell proliferation in the lung of A/J mouse J. Aerosol Med. Pulm. Drug Deliv. 23 2010 285 293 10.1089/jamp.2009.0778
-
(2010)
J. Aerosol Med. Pulm. Drug Deliv.
, vol.23
, pp. 285-293
-
-
Hwang, S.-K.1
Minai-Tehrani, A.2
Lim, H.-T.3
Shin, J.-Y.4
An, G.-H.5
Lee, K.-H.6
-
62
-
-
58549093528
-
Intratracheal versus intravenous liposomal delivery of siRNA, antisense oligonucleotides and anticancer drug
-
O.B. Garbuzenko, M. Saad, S. Betigeri, M. Zhang, A.A. Vetcher, V.A. Soldatenkov, and et al. Intratracheal versus intravenous liposomal delivery of siRNA, antisense oligonucleotides and anticancer drug Pharm. Res. 26 2009 382 394 10.1007/s11095-008-9755-4
-
(2009)
Pharm. Res.
, vol.26
, pp. 382-394
-
-
Garbuzenko, O.B.1
Saad, M.2
Betigeri, S.3
Zhang, M.4
Vetcher, A.A.5
Soldatenkov, V.A.6
-
63
-
-
68549110154
-
The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway
-
H.-L. Jiang, C.-X. Xu, Y.-K. Kim, R. Arote, D. Jere, H.-T. Lim, and et al. The suppression of lung tumorigenesis by aerosol-delivered folate-chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway Biomaterials 30 2009 5844 5852 10.1016/j.biomaterials.2009.07.017
-
(2009)
Biomaterials
, vol.30
, pp. 5844-5852
-
-
Jiang, H.-L.1
Xu, C.-X.2
Kim, Y.-K.3
Arote, R.4
Jere, D.5
Lim, H.-T.6
-
64
-
-
70449629655
-
WT1 gene silencing by aerosol delivery of PEI-RNAi complexes inhibits B16-F10 lung metastases growth
-
D.E. Zamora-Avila, P. Zapata-Benavides, M.A. Franco-Molina, S. Saavedra-Alonso, L.M. Trejo-Avila, D. Reséndez-Pérez, and et al. WT1 gene silencing by aerosol delivery of PEI-RNAi complexes inhibits B16-F10 lung metastases growth Cancer Gene Ther. 16 2009 892 899 10.1038/cgt.2009.35
-
(2009)
Cancer Gene Ther.
, vol.16
, pp. 892-899
-
-
Zamora-Avila, D.E.1
Zapata-Benavides, P.2
Franco-Molina, M.A.3
Saavedra-Alonso, S.4
Trejo-Avila, L.M.5
Reséndez-Pérez, D.6
-
65
-
-
78651341419
-
Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles
-
E.J.B. Nielsen, J.M. Nielsen, D. Becker, A. Karlas, H. Prakash, S.Z. Glud, and et al. Pulmonary gene silencing in transgenic EGFP mice using aerosolised chitosan/siRNA nanoparticles Pharm. Res. 27 2010 2520 2527 10.1007/s11095-010-0255-y
-
(2010)
Pharm. Res.
, vol.27
, pp. 2520-2527
-
-
Nielsen, E.J.B.1
Nielsen, J.M.2
Becker, D.3
Karlas, A.4
Prakash, H.5
Glud, S.Z.6
-
66
-
-
79955468361
-
Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice
-
A. Beyerle, A. Braun, O. Merkel, F. Koch, T. Kissel, and T. Stoeger Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice J. Control. Release 151 2011 51 56 10.1016/j.jconrel.2010.12.017
-
(2011)
J. Control. Release
, vol.151
, pp. 51-56
-
-
Beyerle, A.1
Braun, A.2
Merkel, O.3
Koch, F.4
Kissel, T.5
Stoeger, T.6
-
67
-
-
81255143432
-
Innovative strategy for treatment of lung cancer: Targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA
-
O. Taratula, O.B. Garbuzenko, A.M. Chen, and T. Minko Innovative strategy for treatment of lung cancer: targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA J. Drug Target. 19 2011 900 914 10.3109/1061186X.2011.622404
-
(2011)
J. Drug Target.
, vol.19
, pp. 900-914
-
-
Taratula, O.1
Garbuzenko, O.B.2
Chen, A.M.3
Minko, T.4
-
68
-
-
84880446740
-
Gene silencing in a mouse lung metastasis model by an inhalable dry small interfering RNA powder prepared using the supercritical carbon dioxide technique
-
T. Okuda, D. Kito, A. Oiwa, M. Fukushima, D. Hira, and H. Okamoto Gene silencing in a mouse lung metastasis model by an inhalable dry small interfering RNA powder prepared using the supercritical carbon dioxide technique Biol. Pharm. Bull. 36 2013 1183 1191 10.1248/bpb.b13-00167
-
(2013)
Biol. Pharm. Bull.
, vol.36
, pp. 1183-1191
-
-
Okuda, T.1
Kito, D.2
Oiwa, A.3
Fukushima, M.4
Hira, D.5
Okamoto, H.6
-
69
-
-
84878559366
-
Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes
-
G. Shim, H.-W. Choi, S. Lee, J. Choi, Y.H. Yu, D.-E. Park, and et al. Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes Mol. Ther. 21 2013 816 824 10.1038/mt.2013.10
-
(2013)
Mol. Ther.
, vol.21
, pp. 816-824
-
-
Shim, G.1
Choi, H.-W.2
Lee, S.3
Choi, J.4
Yu, Y.H.5
Park, D.-E.6
-
70
-
-
84940660227
-
Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages
-
L. De Backer, T. Naessens, S. De Koker, E. Zagato, J. Demeester, J. Grooten, and et al. Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages J. Control. Release 217 2015 53 63 10.1016/j.jconrel.2015.08.030
-
(2015)
J. Control. Release
, vol.217
, pp. 53-63
-
-
De Backer, L.1
Naessens, T.2
De Koker, S.3
Zagato, E.4
Demeester, J.5
Grooten, J.6
-
71
-
-
84939943931
-
Emerging insights for translational pharmacokinetic and pharmacokinetic-pharmacodynamic studies: Towards prediction of nose-to-brain transport in humans
-
M.J.R. Ruigrok, and E.C.M. de Lange Emerging insights for translational pharmacokinetic and pharmacokinetic-pharmacodynamic studies: towards prediction of nose-to-brain transport in humans AAPS J. 17 2015 493 505 10.1208/s12248-015-9724-x
-
(2015)
AAPS J.
, vol.17
, pp. 493-505
-
-
Ruigrok, M.J.R.1
De Lange, E.C.M.2
-
72
-
-
0027275566
-
Physiological parameters in laboratory animals and humans
-
B. Davies, and T. Morris Physiological parameters in laboratory animals and humans Pharm. Res. 10 1993 1093 1095 10.1023/A:1018943613122
-
(1993)
Pharm. Res.
, vol.10
, pp. 1093-1095
-
-
Davies, B.1
Morris, T.2
-
73
-
-
35448952967
-
In vivo animal models for drug delivery across the lung mucosal barrier
-
S.-A. Cryan, N. Sivadas, and L. Garcia-Contreras In vivo animal models for drug delivery across the lung mucosal barrier Adv. Drug Deliv. Rev. 59 2007 1133 1151 10.1016/j.addr.2007.08.023
-
(2007)
Adv. Drug Deliv. Rev.
, vol.59
, pp. 1133-1151
-
-
Cryan, S.-A.1
Sivadas, N.2
Garcia-Contreras, L.3
-
74
-
-
84896479654
-
Toxicological assessment of inhaled nanoparticles: Role of in vivo, ex vivo, in vitro, and in silico studies
-
E. Fröhlich, and S. Salar-Behzadi Toxicological assessment of inhaled nanoparticles: role of in vivo, ex vivo, in vitro, and in silico studies Int. J. Mol. Sci. 15 2014 4795 4822 10.3390/ijms15034795
-
(2014)
Int. J. Mol. Sci.
, vol.15
, pp. 4795-4822
-
-
Fröhlich, E.1
Salar-Behzadi, S.2
-
75
-
-
75349108981
-
Preclinical models for pulmonary drug delivery
-
C. a Fernandes, R. Vanbever, Preclinical models for pulmonary drug delivery., Expert Opin. Drug Deliv. 6 (2009) 1231-1245. doi:10.1517/17425240903241788.
-
(2009)
Expert Opin. Drug Deliv
, vol.6
, pp. 1231-1245
-
-
Fernandes, C.A.1
Vanbever, R.2
-
76
-
-
84870520957
-
Precision cut lung slices as an efficient tool for in vitro lung physio-pharmacotoxicology studies
-
J.-P. Morin, J.-M. Baste, A. Gay, C. Crochemore, C. Corbière, and C. Monteil Precision cut lung slices as an efficient tool for in vitro lung physio-pharmacotoxicology studies Xenobiotica 43 2013 63 72 10.3109/00498254.2012.727043
-
(2013)
Xenobiotica
, vol.43
, pp. 63-72
-
-
Morin, J.-P.1
Baste, J.-M.2
Gay, A.3
Crochemore, C.4
Corbière, C.5
Monteil, C.6
-
77
-
-
76749153731
-
Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation
-
D.M.K. Jensen, D. Cun, M.J. Maltesen, S. Frokjaer, H.M.M. Nielsen, and C. Foged Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation J. Control. Release 142 2010 138 145 10.1016/j.jconrel.2009.10.010
-
(2010)
J. Control. Release
, vol.142
, pp. 138-145
-
-
Jensen, D.M.K.1
Cun, D.2
Maltesen, M.J.3
Frokjaer, S.4
Nielsen, H.M.M.5
Foged, C.6
-
78
-
-
84855837134
-
Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA
-
D.K. Jensen, L.B. Jensen, S. Koocheki, L. Bengtson, D. Cun, H.M.M. Nielsen, and et al. Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA J. Control. Release 157 2012 141 148 10.1016/j.jconrel.2011.08.011
-
(2012)
J. Control. Release
, vol.157
, pp. 141-148
-
-
Jensen, D.K.1
Jensen, L.B.2
Koocheki, S.3
Bengtson, L.4
Cun, D.5
Nielsen, H.M.M.6
-
79
-
-
84924039536
-
Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virus
-
W. Liang, M.Y.T. Chow, P.N. Lau, Q.T. Zhou, P.C.L. Kwok, G.P.H. Leung, and et al. Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virus Mol. Pharm. 12 2015 910 921 10.1021/mp500745v
-
(2015)
Mol. Pharm.
, vol.12
, pp. 910-921
-
-
Liang, W.1
Chow, M.Y.T.2
Lau, P.N.3
Zhou, Q.T.4
Kwok, P.C.L.5
Leung, G.P.H.6
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