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Volumn 26, Issue 3, 2013, Pages 165-173

Lentivirus-AIMP2-DX2 shRNA suppresses cell proliferation by regulating akt1 signaling pathway in the lungs of AIMP2 Mice

Author keywords

aerosol gene delivery; Akt1 signaling pathway; angiogenesis; shRNA AIMP2 DX2

Indexed keywords

AKT1 PROTEIN; AMINO ACID TRANSFER RNA LIGASE; AMINO ACID TRANSFER RNA LIGASE INTERACTING MULTIFUNCTIONAL PROTEIN; ANTINEOPLASTIC AGENT; DX2 PROTEIN; LENTIVIRUS VECTOR; PROTEIN KINASE B; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

EID: 84878415381     PISSN: 19412711     EISSN: 19412703     Source Type: Journal    
DOI: 10.1089/jamp.2011.0959     Document Type: Article
Times cited : (13)

References (31)
  • 1
    • 9644294208 scopus 로고    scopus 로고
    • Modified polyethylenimines as non viral gene delivery systems for aerosol therapy: Effects of nebulization on cellular uptake and transfection efficiency
    • Dailey LA, Kleemann E, Merdan T, Petersen H, Schmehl T, Gessler T, Hanze J, Seeger W, and Kissel T: Modified polyethylenimines as non viral gene delivery systems for aerosol therapy: effects of nebulization on cellular uptake and transfection efficiency. J Control Release. 2004;100:425-436.
    • (2004) J Control Release , vol.100 , pp. 425-436
    • Dailey, L.A.1    Kleemann, E.2    Merdan, T.3    Petersen, H.4    Schmehl, T.5    Gessler, T.6    Hanze, J.7    Seeger, W.8    Kissel, T.9
  • 2
    • 0037027911 scopus 로고    scopus 로고
    • Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis
    • Ferrari S, Geddes DM, and Alton EW: Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis. Adv Drug Deliv Rev. 2002;54:1373-1393.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1373-1393
    • Ferrari, S.1    Geddes, D.M.2    Alton, E.W.3
  • 3
    • 0037072576 scopus 로고    scopus 로고
    • Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
    • Merdan T, Kopecek J, and Kissel T: Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev. 2002;54:715-758.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 715-758
    • Merdan, T.1    Kopecek, J.2    Kissel, T.3
  • 5
    • 33644975338 scopus 로고    scopus 로고
    • Advances in noninvasive pulmonary gene therapy
    • Densmore CL: Advances in noninvasive pulmonary gene therapy. Curr Drug Deliv. 2006;3:55-63.
    • (2006) Curr Drug Deliv , vol.3 , pp. 55-63
    • Densmore, C.L.1
  • 6
    • 0028328261 scopus 로고
    • Cellular immunity to viral antigens limits El-deleted adenoviruses for gene therapy
    • Yang Y, Nunes FA, and Berencsi K: Cellular immunity to viral antigens limits El-deleted adenoviruses for gene therapy. Proc Natl Acad Sci USA. 1994;91:4407-4411.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4407-4411
    • Yang, Y.1    Nunes, F.A.2    Berencsi, K.3
  • 7
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller D, Adam MA, and Miller AD: Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol. 1992;10:4239-4242.
    • (1992) Mol Cell Biol , vol.10 , pp. 4239-4242
    • Miller, D.1    Adam, M.A.2    Miller, A.D.3
  • 8
    • 0030716959 scopus 로고    scopus 로고
    • Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors
    • Kafri T, Blomer U, and Peterson DA: Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat Genet. 1997;17: 314-317.
    • (1997) Nat Genet , vol.17 , pp. 314-317
    • Kafri, T.1    Blomer, U.2    Peterson, D.A.3
  • 9
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ, and Rossi JJ: Unlocking the potential of the human genome with RNA interference. Nature. 2004;431: 371-378.
    • (2004) Nature , vol.431 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 10
    • 14644393684 scopus 로고    scopus 로고
    • Perspective: Machines for RNAi
    • Tomari Y, and Zamore PD: Perspective: machines for RNAi. Genes Dev. 2005;19:517-529.
    • (2005) Genes Dev , vol.19 , pp. 517-529
    • Tomari, Y.1    Zamore, P.D.2
  • 12
    • 0029993858 scopus 로고    scopus 로고
    • Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
    • Luigi N, Ulrike B, Fred HG, Didier T, and Inder MV: Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci USA. 1996;93:11382-11388.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11382-11388
    • Luigi, N.1    Ulrike, B.2    Fred, H.G.3    Didier, T.4    Inder, M.V.5
  • 13
    • 4444369924 scopus 로고    scopus 로고
    • Aminoacyl-tRNA synthetase complexes: Beyond translation
    • Lee SW, Cho BH, Park SG, and Kim S: Aminoacyl-tRNA synthetase complexes: beyond translation. J Cell Sci. 2004; 117:3725-3734.
    • (2004) J Cell Sci , vol.117 , pp. 3725-3734
    • Lee, S.W.1    Cho, B.H.2    Park, S.G.3    Kim, S.4
  • 14
    • 25144489447 scopus 로고    scopus 로고
    • Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: New perspectives on housekeepers
    • Park SG, Ewalt KL, and Kim S: Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers. Trends Biochem Sci. 2005;30:569-574.
    • (2005) Trends Biochem Sci , vol.30 , pp. 569-574
    • Park, S.G.1    Ewalt, K.L.2    Kim, S.3
  • 15
    • 1342287127 scopus 로고    scopus 로고
    • The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FceRI-activated mast cells
    • Lee YN, Nechushtan H, Figov N, and Razin E: The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FceRI-activated mast cells. Immunity. 2004;20:145-151.
    • (2004) Immunity , vol.20 , pp. 145-151
    • Lee, Y.N.1    Nechushtan, H.2    Figov, N.3    Razin, E.4
  • 17
    • 0037743658 scopus 로고    scopus 로고
    • Downregulation of FUSEbinding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation
    • Kim MJ, Park BJ, Kang YS, Kim HJ, Park JH, Kang JW, Lee SW, Han JM, Lee HW, and Kim S: Downregulation of FUSEbinding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation. Nat Genet. 2003; 34:330-336.
    • (2003) Nat Genet , vol.34 , pp. 330-336
    • Kim, M.J.1    Park, B.J.2    Kang, Y.S.3    Kim, H.J.4    Park, J.H.5    Kang, J.W.6    Lee, S.W.7    Han, J.M.8    Lee, H.W.9    Kim, S.10
  • 19
    • 84878401921 scopus 로고    scopus 로고
    • Korean Patent Application 10-2004-0097164, 10-2005-39073
    • Kim S: Aimp2-dx2 and its uses. Korean Patent Application. 2004, 2005; 10-2004-0097164, 10-2005-39073.
    • (2004) Aimp2-dx2 and Its Uses , vol.2005
    • Kim, S.1
  • 21
    • 0030758704 scopus 로고    scopus 로고
    • Angiogenesis: A dynamic balance of stimulators and inhibitors
    • Iruela-Arispe ML, and Dvorak HF: Angiogenesis: a dynamic balance of stimulators and inhibitors. Thromb Haemost. 1997;78:672-677.
    • (1997) Thromb Haemost , vol.78 , pp. 672-677
    • Iruela-Arispe, M.L.1    Dvorak, H.F.2
  • 22
    • 0031456444 scopus 로고    scopus 로고
    • Aminoacyl-tRNA synthetases
    • Cusack S: Aminoacyl-tRNA synthetases. Curr Opin Struct Biol. 1997;7:881-889.
    • (1997) Curr Opin Struct Biol , vol.7 , pp. 881-889
    • Cusack, S.1
  • 23
    • 70249139462 scopus 로고    scopus 로고
    • Multidirectional tumor-suppressive activity of AIMP2/p38 and the enhanced susceptibility of AIMP2 heterozygous mice to carcinogenesis
    • Choi JW, Um JY, Kundu JK, Surh YJ, and Kim S: Multidirectional tumor-suppressive activity of AIMP2/p38 and the enhanced susceptibility of AIMP2 heterozygous mice to carcinogenesis. Carcinogenesis. 2009;30:1638-1644.
    • (2009) Carcinogenesis , vol.30 , pp. 1638-1644
    • Choi, J.W.1    Um, J.Y.2    Kundu, J.K.3    Surh, Y.J.4    Kim, S.5
  • 27
    • 2342559981 scopus 로고    scopus 로고
    • The TOR pathway: A target for cancer therapy
    • Bjornsti MA, and Houghton PJ: The TOR pathway: a target for cancer therapy. Nat Rev Cancer. 2004;4:335-348.
    • (2004) Nat Rev Cancer , vol.4 , pp. 335-348
    • Bjornsti, M.A.1    Houghton, P.J.2
  • 28
    • 0345732640 scopus 로고    scopus 로고
    • MTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
    • Fingar DC, Richardson CJ, Tee AR, Cheatham L, Tsou C, and Blenis J: mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol Cell Biol. 2004;24: 200-216.
    • (2004) Mol Cell Biol , vol.24 , pp. 200-216
    • Fingar, D.C.1    Richardson, C.J.2    Tee, A.R.3    Cheatham, L.4    Tsou, C.5    Blenis, J.6
  • 31
    • 0037351665 scopus 로고    scopus 로고
    • Increased levels of the translation initiation factor eIF4E in differentiating epithelial lung tumor cell lines
    • Walsh D, Meleady P, Power B, Morley SJ, and Clynes M: Increased levels of the translation initiation factor eIF4E in differentiating epithelial lung tumor cell lines. Differentiation. 2003;71:126-134.
    • (2003) Differentiation , vol.71 , pp. 126-134
    • Walsh, D.1    Meleady, P.2    Power, B.3    Morley, S.J.4    Clynes, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.