메뉴 건너뛰기




Volumn , Issue , 2009, Pages 115-146

Computational biology of small regulatory RNAs

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL BIOLOGY; REGULATORY RNAS;

EID: 84970949861     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1142/9789812838780_0005     Document Type: Chapter
Times cited : (1)

References (136)
  • 1
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 rna regulates developmental timing in caenorhabditis elegans
    • Reinhart B, Slack F, Basson M et al. (2000) The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403: 901-906.
    • (2000) Nature , vol.403 , pp. 90-96
    • Reinhart, B.1    Slack, F.2    Basson, M.3
  • 2
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory rna
    • Pasquinelli A, Reinhart B, Slack F et al. (2000) Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408: 86-89.
    • (2000) Nature , vol.408 , pp. 8-9
    • Pasquinelli, A.1    Reinhart, B.2    Slack, F.3
  • 3
    • 0035955374 scopus 로고    scopus 로고
    • Identificationof novel genes coding for small expressed rnas
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. (2001) Identification of novel genes coding for small expressed RNAs. Science 294: 853-858.
    • (2001) Science , vol.294 , pp. 85-88
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 4
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissuespecific micrornas from mouse
    • Lagos-Quintana M, Rauhut R, Yalcin A et al. (2002) Identification of tissuespecific microRNAs from mouse. Curr Biol 12: 735-739.
    • (2002) Curr Biol , vol.12 , pp. 73-79
    • Lagos-Quintana, M.1    Rauhut, R.2    Yalcin, A.3
  • 5
    • 2342420041 scopus 로고    scopus 로고
    • Small rna profiling of virusinfected human cells identifies viral micrornas
    • Pfeffer S, Zavolan M, Grässer F et al. (2004) Small RNA profiling of virusinfected human cells identifies viral microRNAs. Science 304: 734-736.
    • (2004) Science , vol.304 , pp. 73-76
    • Pfeffer, S.1    Zavolan, M.2    Grässer, F.3
  • 6
    • 0027751663 scopus 로고
    • The c. Elegans heterochronic gene lin-4 encodes small rnas with antisense complementarity to lin-14
    • Lee R, Feinbaum R, Ambros V. (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854.
    • (1993) Cell , vol.75 , pp. 8-54
    • Lee, R.1    Feinbaum, R.2    Ambros, V.3
  • 7
    • 3242736704 scopus 로고    scopus 로고
    • Human argonaute2 mediates rna cleavage targeted by mirnas and sirnas
    • Meister G, Landthaler M, Patkaniowska A et al. (2004) Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell 15: 185-197.
    • (2004) Mol Cell , vol.15 , pp. 1-97
    • Meister, G.1    Landthaler, M.2    Patkaniowska, A.3
  • 8
    • 4444368187 scopus 로고    scopus 로고
    • Argonaute2 is the catalytic engine of mammalian rnai
    • Liu J, Carmell M, Rivas F et al. (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science 305: 1437-1441.
    • (2004) Science , vol.305 , pp. 14-41
    • Liu, J.1    Carmell, M.2    Rivas, F.3
  • 9
    • 84970975432 scopus 로고    scopus 로고
    • Ago1 defines a novel locus of ar10. Moussian b, schoof h, haecker a et al. (1998) role of the zwille gene in the regulation of central shoot meristem cell fate during arabidopsis embryogenesis
    • Bohmert K, Camus I, Bellini C et al. (1998) AGO1 defines a novel locus of Ar10. Moussian B, Schoof H, Haecker A et al. (1998) Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis. EMBO J 17: 1799-809.
    • (1998) EMBO J , vol.17 , pp. 1799-1809
    • Bohmert, K.1    Camus, I.2    Bellini, C.3
  • 10
    • 0033639116 scopus 로고    scopus 로고
    • A global profile of germline gene expression in c. Elegans
    • Reinke V, Smith H, Nance J et al. (2000) A global profile of germline gene expression in C. elegans. Mol Cell 6: 605-616.
    • (2000) Mol Cell , vol.6 , pp. 6-16
    • Reinke, V.1    Smith, H.2    Nance, J.3
  • 11
    • 0033966406 scopus 로고    scopus 로고
    • Lin h. (2000) piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells
    • Cox D, Chao A, Lin H. (2000) piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells. Development 127: 503-514.
    • Development , vol.127 , pp. 5-14
    • Cox, D.1    Chao, A.2
  • 12
    • 33745402414 scopus 로고    scopus 로고
    • A novel class of small rnas bind to mili protein in mouse testes
    • Aravin A, Gaidatzis D, Pfeffer S et al. (2006) A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442: 203-207.
    • (2006) Nature , vol.442 , pp. 20-27
    • Aravin, A.1    Gaidatzis, D.2    Pfeffer, S.3
  • 13
    • 33745336617 scopus 로고    scopus 로고
    • A germlinespecific class of small rnas binds mammalian piwi proteins
    • Girard A, Sachidanandam R, Hannon G, Carmell M. (2006) A germlinespecific class of small RNAs binds mammalian Piwi proteins. Nature 442: 199-202.
    • (2006) Nature , vol.442 , pp. 199-202
    • Girard, A.1    Sachidanandam, R.2    Hannon, G.3    Carmell, M.4
  • 14
    • 33746527679 scopus 로고    scopus 로고
    • Characterization of the pirna complex from rat testes
    • Lau N, Seto A, Kim J et al. (2006) Characterization of the piRNA complex from rat testes. Science 313: 363-367.
    • (2006) Science , vol.313 , pp. 36-37
    • Lau, N.1    Seto, A.2    Kim, J.3
  • 15
    • 33747369856 scopus 로고    scopus 로고
    • Specific association of piwi with rasirnas derived from retrotransposon and heterochromatic regions in the drosophila genome
    • Saito K, Nishida K, Mori T et al. (2006) Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev 20: 2214-2222.
    • (2006) Genes Dev , vol.20 , pp. 22-23
    • Saito, K.1    Nishida, K.2    Mori, T.3
  • 16
    • 33947273235 scopus 로고    scopus 로고
    • Discrete small rna-generating locias master regulators of transposon activity in drosophila
    • Brennecke J, Aravin A, Stark A et al. (2007) Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 128: 1089-1103.
    • (2007) Cell , vol.128 , pp. 1-103
    • Brennecke, J.1    Aravin, A.2    Stark, A.3
  • 17
    • 33947390781 scopus 로고    scopus 로고
    • A slicer-mediated mechanism for repeat-associated sirna 5′ end formation in drosophila
    • Gunawardane L, Saito K, Nishida K et al. (2007) A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila. Science 315: 1587-1590.
    • (2007) Science , vol.315 , pp. 15-90
    • Gunawardane, L.1    Saito, K.2    Nishida, K.3
  • 18
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny rnas with probable regulatory roles in caenorhabditis elegans
    • Lau N, Lim L, Weinstein E, Bartel D. (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858-862.
    • (2001) Science , vol.294 , pp. 8-62
    • Lau, N.1    Lim, L.2    Weinstein, E.3    Bartel, D.4
  • 19
    • 0035955366 scopus 로고    scopus 로고
    • An extensive classof small rnas in caenorhabditis elegans
    • Lee R, Ambros V. (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science 294: 797-799.
    • (2001) Science , vol.294 , pp. 79-80
    • Lee, R.1    Ambros, V.2
  • 21
    • 24044455869 scopus 로고    scopus 로고
    • Genome sequencing in microfabricated high-density picolitre reactors
    • Margulies M, Egholm M, Altman W et al. (2005) Genome sequencing in microfabricated high-density picolitre reactors. Nature 437: 376-380.
    • (2005) Nature , vol.437 , pp. 3-80
    • Margulies, M.1    Egholm, M.2    Altman, W.3
  • 23
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human micrornas
    • Bentwich I, Avniel A, Karov Y et al. (2005) Identification of hundreds of conserved and nonconserved human microRNAs. Nat Genet 37: 766-770.
    • (2005) Nat Genet , vol.37 , pp. 7-70
    • Bentwich, I.1    Avniel, A.2    Karov, Y.3
  • 24
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microrna expression atlas based on small rna library sequencing
    • Landgraf P, Rusu M, Sheridan R et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129: 1401-1414.
    • (2007) Cell , vol.129 , pp. 14-15
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 25
    • 4143142117 scopus 로고    scopus 로고
    • Microrna profiling reveals distinct signatures in b cell chronic lymphocytic leukemias
    • Calin G, Liu C, Sevignani C et al. (2004) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 101: 11755-11760.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 60-117
    • Calin, G.1    Liu, C.2    Sevignani, C.3
  • 26
    • 5344273958 scopus 로고    scopus 로고
    • Microarray analysis of microrna expression in the developing mammalian brain
    • Miska E, Alvarez-Saavedra E, Townsend M et al. (2004) Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol 5: R68.
    • (2004) Genome Biol , vol.5 , pp. 68
    • Miska, E.1    Alvarez-Saavedra, E.2    Townsend, M.3
  • 27
    • 7044285911 scopus 로고    scopus 로고
    • Probing micrornas with microarrays: Tissue specificity and functional inference
    • Babak T, Zhang W, Morris Q et al. (2004) Probing microRNAs with microarrays: tissue specificity and functional inference. RNA 10: 1813-1819.
    • (2004) RNA , vol.10 , pp. 18-19
    • Babak, T.1    Zhang, W.2    Morris, Q.3
  • 28
    • 19944412146 scopus 로고    scopus 로고
    • Microrna expression detected by oligonucleotide microarrays: System establishment and expression profiling in human tissues
    • Barad O, Meiri E, Avniel A et al. (2004) MicroRNA expression detected by oligonucleotide microarrays: system establishment and expression profiling in human tissues. Genome Res 14: 2486-94.
    • (2004) Genome Res , vol.14 , pp. 2486-2494
    • Barad, O.1    Meiri, E.2    Avniel, A.3
  • 29
    • 19744383402 scopus 로고    scopus 로고
    • An oligonucleotide microarray for microrna expression analysis based on labeling rna with quantum dot and nanogold probe
    • Liang R, Li W, Li Y et al. (2005) An oligonucleotide microarray for microRNA expression analysis based on labeling RNA with quantum dot and nanogold probe. Nucleic Acids Res 33: e17.
    • (2005) Nucleic Acids Res , vol.33 , Issue.17
    • Liang, R.1    Li, W.2    Li, Y.3
  • 30
    • 22044458072 scopus 로고    scopus 로고
    • Microrna expression in zebrafish embryonic development
    • Wienholds E, Kloosterman W, Miska E et al. (2005) MicroRNA expression in zebrafish embryonic development. Science 309: 310-311.
    • (2005) Science , vol.309 , pp. 310-311
    • Wienholds, E.1    Kloosterman, W.2    Miska, E.3
  • 31
    • 34249857357 scopus 로고    scopus 로고
    • A novel microarray approach reveals new tissue-specific signatures of known and predicted mammalian micrornas
    • Beuvink I, Kolb F, Budach W et al. (2007) A novel microarray approach reveals new tissue-specific signatures of known and predicted mammalian microRNAs. Nucleic Acids Res 35: e52.
    • (2007) Nucleic Acids Res , vol.35 , Issue.52
    • Beuvink, I.1    Kolb, F.2    Budach, W.3
  • 32
    • 0347444723 scopus 로고    scopus 로고
    • Micrornas: Genomics, biogenesis, mechanism, and function
    • Bartel D. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 2-7
    • Bartel, D.1
  • 33
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear rnase iii drosha initiates microrna processing
    • Lee Y, Ahn C, Han J et al. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature 425: 415-429.
    • (2003) Nature , vol.425 , pp. 4-9
    • Lee, Y.1    Ahn, C.2    Han, J.3
  • 34
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary micrornas by the microprocessor complex
    • Denli A, Tops B, Plasterk R et al. (2004) Processing of primary microRNAs by the Microprocessor complex. Nature 432: 231-235.
    • (2004) Nature , vol.432 , pp. 23-25
    • Denli, A.1    Tops, B.2    Plasterk, R.3
  • 35
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of rna interference
    • Bernstein E, Caudy A, Hammond S, Hannon G. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366.
    • (2001) Nature , vol.409 , pp. 36-38
    • Bernstein, E.1    Caudy, A.2    Hammond, S.3    Hannon, G.4
  • 36
    • 22744433240 scopus 로고    scopus 로고
    • Normal microrna maturation and germ-line stem cell maintenance requires loquacious, a double-stranded rna-binding domain protein
    • Förstemann K, Tomari Y, Du T et al. (2005) Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol 3: e236.
    • (2005) Plos Biol , vol.3 , Issue.236
    • Förstemann, K.1    Tomari, Y.2    Du, T.3
  • 37
    • 23644433363 scopus 로고    scopus 로고
    • Trbp recruits the dicer complex to ago2 for microrna processing and gene silencing
    • Chendrimada T, Gregory R, Kumaraswamy E et al. (2005) TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Cell 436: 740-744.
    • (2005) Cell , vol.436 , pp. 74-77
    • Chendrimada, T.1    Gregory, R.2    Kumaraswamy, E.3
  • 38
    • 27144550559 scopus 로고    scopus 로고
    • Trbp, a regulator of cellular pkr and hiv-1 virus expression, interacts with dicer and functions in rna silencing
    • Haase A, Jaskiewicz L, Zhang H et al. (2005) TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep 6: 961-967.
    • (2005) EMBO Rep , vol.6 , pp. 96-97
    • Haase, A.1    Jaskiewicz, L.2    Zhang, H.3
  • 39
    • 0024817130 scopus 로고
    • Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in caenorhabditis elegans
    • Liu Z, Ambros V. (1989) Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans. Genes Dev 3: 2039-2049.
    • (1989) Genes Dev , vol.3 , pp. 20-49
    • Liu, Z.1    Ambros, V.2
  • 40
    • 0019509303 scopus 로고
    • Mutations that lead to reiterations in the cell lineages of c. Elegans
    • Chalfie M, Horvitz H, Sulston J. (1981) Mutations that lead to reiterations in the cell lineages of C. elegans. Cell 24: 59-69.
    • (1981) Cell , vol.24 , pp. 59-69
    • Chalfie, M.1    Horvitz, H.2    Sulston, J.3
  • 41
    • 0021771445 scopus 로고
    • Heterochronic mutants of the nematode caenorhabditis elegans
    • Ambros V, Horvitz H. (1984) Heterochronic mutants of the nematode Caenorhabditis elegans. Science 226: 409-416.
    • (1984) Science , vol.226 , pp. 4-16
    • Ambros, V.1    Horvitz, H.2
  • 42
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in c. Elegans
    • Wightman B, Ha I, Ruvkun G. (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855-862.
    • (1993) Cell , vol.75 , pp. 8-62
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 43
    • 0038708326 scopus 로고    scopus 로고
    • The caenorhabditis elegans hunchbacklike gene lin-57/hbl-1 controls developmental time and is regulated by micrornas
    • Abrahante J, Daul A, Li M et al. (2003) The Caenorhabditis elegans hunchbacklike gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell 4: 625-637.
    • (2003) Dev Cell , vol.4 , pp. 6-37
    • Abrahante, J.1    Daul, A.2    Li, M.3
  • 44
    • 0037693842 scopus 로고    scopus 로고
    • The c. Elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microrna target
    • Lin S, Johnson S, Abraham M et al. (2003) The C. elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev Cell 4: 639-650.
    • (2003) Dev Cell , vol.4 , pp. 6-50
    • Lin, S.1    Johnson, S.2    Abraham, M.3
  • 45
    • 0036535323 scopus 로고    scopus 로고
    • The expression of the let-7 small regulatory rna is controlled by ecdysone during metamorphosis in drosophila melanogaster
    • Sempere L, Dubrovsky E, Dubrovskaya V et al. (2002) The expression of the let-7 small regulatory RNA is controlled by ecdysone during metamorphosis in Drosophila melanogaster. Dev Biol 244: 170-179.
    • (2002) Dev Biol , vol.244 , pp. 1-79
    • Sempere, L.1    Dubrovsky, E.2    Dubrovskaya, V.3
  • 47
    • 0037423845 scopus 로고    scopus 로고
    • Vertebrate microrna genes
    • Lim L, Glasner M, Yekta S et al. (2003) Vertebrate microRNA genes. Science 299: 1540.
    • (2003) Science , vol.299 , pp. 1540
    • Lim, L.1    Glasner, M.2    Yekta, S.3
  • 48
    • 20844463414 scopus 로고    scopus 로고
    • Identification of micrornas of the herpesvirus family
    • Pfeffer S, Sewer A, Lagos-Quintana M et al. (2005) Identification of microRNAs of the herpesvirus family. Nat Methods 2: 269-276.
    • (2005) Nat Methods , vol.2 , pp. 2-76
    • Pfeffer, S.1    Sewer, A.2    Lagos-Quintana, M.3
  • 49
    • 21644438873 scopus 로고    scopus 로고
    • Cloning and identification of amicrorna cluster within the latency-associated region of kaposi’s sarcomaassociated herpesvirus
    • Samols M, Hu J, Skalsky R, Renne R. (2005) Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi’s sarcomaassociated herpesvirus. J Virol 79: 9301-9305.
    • (2005) J Virol , vol.79 , pp. 930-935
    • Samols, M.1    Hu, J.2    Skalsky, R.3    Renne, R.4
  • 50
    • 17244375710 scopus 로고    scopus 로고
    • Kaposi’s sarcoma-associated herpesvirus expresses an array of viral micrornas in latently infected cells
    • Cai X, Lu S, Zhang Z et al. (2005) Kaposi’s sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci USA 102: 5570-5575.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 557-559
    • Cai, X.1    Lu, S.2    Zhang, Z.3
  • 51
    • 24644484014 scopus 로고    scopus 로고
    • Identification and characterization of human cytomegalovirus-encoded micrornas
    • Grey F, Antoniewicz A, Allen E et al. (2005) Identification and characterization of human cytomegalovirus-encoded microRNAs. J Virol 79: 12095-12099.
    • (2005) J Virol , vol.79 , pp. 1209-1211
    • Grey, F.1    Antoniewicz, A.2    Allen, E.3
  • 52
    • 20444446357 scopus 로고    scopus 로고
    • Sv40-encoded micrornas regulate viral gene expression and reduce susceptibility to cytotoxic t cells
    • Sullivan C, Grundhoff A, Tevethia S et al. (2005) SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells. Nature 435: 682-686.
    • (2005) Nature , vol.435 , pp. 68-69
    • Sullivan, C.1    Grundhoff, A.2    Tevethia, S.3
  • 53
    • 39149129648 scopus 로고    scopus 로고
    • Epstein-barr virus-encoded microrna mir-bart2 down-regulates the viral dna polymerase balf5
    • Barth S, Pfuhl T, Mamiani A et al. (2007) Epstein-Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5. Nucleic Acids Res 36: 666-675.
    • (2007) Nucleic Acids Res , vol.36 , pp. 6-75
    • Barth, S.1    Pfuhl, T.2    Mamiani, A.3
  • 54
    • 0030755562 scopus 로고    scopus 로고
    • A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the drosophila ovary
    • Lin H, Spradling A. (1997) A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Development 124: 2463-2476.
    • (1997) Development , vol.124 , pp. 24-76
    • Lin, H.1    Spradling, A.2
  • 55
    • 0942279615 scopus 로고    scopus 로고
    • Heterochromatic silencing and hp1 localization in drosophila are dependent on the rnai machinery
    • Pal-Bhadra M, Leibovitch B, Gandhi S et al. (2004) Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 303: 669-672.
    • (2004) Science , vol.303 , pp. 6-72
    • Pal-Bhadra, M.1    Leibovitch, B.2    Gandhi, S.3
  • 56
    • 0041941514 scopus 로고    scopus 로고
    • The small rna profile during drosophila melanogaster development
    • Aravin A, Lagos-Quintana M, Yalcin A et al. (2003) The small RNA profile during Drosophila melanogaster development. Dev Cell 5: 337-350.
    • (2003) Dev Cell , vol.5 , pp. 3-50
    • Aravin, A.1    Lagos-Quintana, M.2    Yalcin, A.3
  • 57
    • 0036083480 scopus 로고    scopus 로고
    • Lin h. (2002) miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis
    • Deng W, Lin H. (2002) miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev Cell 2: 819-830.
    • Dev Cell , vol.2 , pp. 8-30
    • Deng, W.1
  • 58
    • 10744223519 scopus 로고    scopus 로고
    • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
    • Kuramochi-Miyagawa S, Kimura T, Ijiri T et al. (2004) Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development 131: 839-849.
    • (2004) Development , vol.131 , pp. 8-49
    • Kuramochi-Miyagawa, S.1    Kimura, T.2    Ijiri, T.3
  • 59
    • 34248160438 scopus 로고    scopus 로고
    • Developmentally regulated pirna clusters implicate mili in transposon control
    • Aravin A, Sachidanandam R, Girard A et al. (2007) Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316: 744-747.
    • (2007) Science , vol.316 , pp. 74-77
    • Aravin, A.1    Sachidanandam, R.2    Girard, A.3
  • 60
    • 34047154356 scopus 로고    scopus 로고
    • A role for piwi and pirnas in germ cell maintenance and transposon silencing in zebrafish
    • Houwing S, Kamminga L, Berezikov E et al. (2007) A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell 129: 69-82.
    • (2007) Cell , vol.129 , pp. 69-82
    • Houwing, S.1    Kamminga, L.2    Berezikov, E.3
  • 61
    • 33644750115 scopus 로고    scopus 로고
    • Grocock r, van dongen s et al. (2006) mirbase: Microrna sequences, targets and gene nomenclature
    • Griffiths-Jones S, Grocock R, van Dongen S et al. (2006) miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34: D140-144.
    • Nucleic Acids Res , vol.34 , pp. 14-15
    • Griffiths-Jones, S.1
  • 62
    • 8144225486 scopus 로고    scopus 로고
    • Microrna genes are transcribed by rna polymerase ii
    • Lee Y, Kim M, Han J et al. (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23: 4051-4060.
    • (2004) EMBO J , vol.23 , pp. 40-60
    • Lee, Y.1    Kim, M.2    Han, J.3
  • 63
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-micrornas and short hairpin rnas
    • Yi R, Qin Y, Macara I, Cullen B. (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17: 3011-3016.
    • (2003) Genes Dev , vol.17 , pp. 301-306
    • Yi, R.1    Qin, Y.2    Macara, I.3    Cullen, B.4
  • 64
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microrna precursors
    • Lund E, Güttinger S, Calado A et al. (2004) Nuclear export of microRNA precursors. Science 303: 95-98.
    • (2004) Science , vol.303 , pp. 8-9
    • Lund, E.1    Güttinger, S.2    Calado, A.3
  • 65
    • 8844271740 scopus 로고    scopus 로고
    • A protein sensor for sirnaasymmetry
    • Tomari Y, Matranga C, Haley B et al. (2004) A protein sensor for siRNA asymmetry. Science 306: 1377-80.
    • (2004) Science , vol.306 , pp. 1377-1380
    • Tomari, Y.1    Matranga, C.2    Haley, B.3
  • 66
    • 1842766252 scopus 로고    scopus 로고
    • A dicer-2-dependent 80s complex cleaves targeted mrnas during rnai in drosophila
    • Pham J, Pellino J, Lee Y et al. (2004) A Dicer-2-dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117: 83-94.
    • (2004) Cell , vol.117 , pp. 83-94
    • Pham, J.1    Pellino, J.2    Lee, Y.3
  • 67
    • 1642603943 scopus 로고    scopus 로고
    • Risc assembly defects in the drosophila rnai mutant armitage
    • Tomari Y, Du T, Haley B et al. (2004) RISC assembly defects in the Drosophila RNAi mutant armitage. Cell 116: 831-841.
    • (2004) Cell , vol.116 , pp. 8-41
    • Tomari, Y.1    Du, T.2    Haley, B.3
  • 68
    • 0037144457 scopus 로고    scopus 로고
    • Cleavage of scarecrow-like mrna targets directed by a class of arabidopsis mirna
    • Llave C, Xie Z, Kasschau K, Carrington J. (2002) Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science 297: 2053-2056.
    • (2002) Science , vol.297 , pp. 205-206
    • Llave, C.1    Xie, Z.2    Kasschau, K.3    Carrington, J.4
  • 69
    • 3042767202 scopus 로고    scopus 로고
    • Micrornas: Small rnas with a big role in gene regulation
    • He L, Hannon G. (2004) MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 5: 522-531.
    • (2004) Nat Rev Genet , vol.5 , pp. 5-31
    • He, L.1    Hannon, G.2
  • 70
    • 28544435974 scopus 로고    scopus 로고
    • Disruption of gw bodies impairs mammalian rna interference
    • Jakymiw A, Lian S, Eystathioy T et al. (2005) Disruption of GW bodies impairs mammalian RNA interference. Nat Cell Biol 7: 1267-1274.
    • (2005) Nat Cell Biol , vol.7 , pp. 12-74
    • Jakymiw, A.1    Lian, S.2    Eystathioy, T.3
  • 71
    • 22144478256 scopus 로고    scopus 로고
    • Microrna-dependent localization of targeted mrnas to mammalian p-bodies
    • Liu J, Valencia-Sanchez M, Hannon G, Parker R. (2005) MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat Cell Biol 7: 719-723.
    • (2005) Nat Cell Biol , vol.7 , pp. 7-23
    • Liu, J.1    Valencia-Sanchez, M.2    Hannon, G.3    Parker, R.4
  • 72
    • 25844442472 scopus 로고    scopus 로고
    • A crucial role for gw182 and the dcp1:Dcp2 decapping complex in mirna-mediated gene silencing
    • Rehwinkel J, Behm-Ansmant I, Gatfield D, Izaurralde E. (2005) A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. RNA 11: 1640-1647.
    • (2005) RNA , vol.11 , pp. 164-167
    • Rehwinkel, J.1    Behm-Ansmant, I.2    Gatfield, D.3    Izaurralde, E.4
  • 73
    • 0036223709 scopus 로고    scopus 로고
    • A phosphorylated cytoplasmic autoantigen, gw182, associates with a unique population of human mrnas within novel cytoplasmic speckles
    • Eystathioy T, Chan E, Tenenbaum S et al. (2002) A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Mol Biol Cell 13: 1338-1351.
    • (2002) Mol Biol Cell , vol.13 , pp. 13-51
    • Eystathioy, T.1    Chan, E.2    Tenenbaum, S.3
  • 74
    • 33744973775 scopus 로고    scopus 로고
    • Relief of micrornamediated translational repression in human cells subjected to stress
    • Bhattacharyya S, Habermacher R, Martine U et al. (2006) Relief of microRNAmediated translational repression in human cells subjected to stress. Cell 125: 1111-1124.
    • (2006) Cell , vol.125 , pp. 11-24
    • Bhattacharyya, S.1    Habermacher, R.2    Martine, U.3
  • 75
    • 38349118916 scopus 로고    scopus 로고
    • Rna-binding protein dnd1 inhibits microrna access to target mrna
    • Kedde M, Strasser M, Boldajipour B et al. (2007) RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. Cell 131: 1273-1286.
    • (2007) Cell , vol.131 , pp. 12-86
    • Kedde, M.1    Strasser, M.2    Boldajipour, B.3
  • 76
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of argonaute and its implications for risc slicer activity
    • Song J, Smith S, Hannon G, Joshua-Tor L. (2004) Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305: 1434-1437.
    • (2004) Science , vol.305 , pp. 143-147
    • Song, J.1    Smith, S.2    Hannon, G.3    Joshua-Tor, L.4
  • 77
    • 11244279683 scopus 로고    scopus 로고
    • Crystal structure of a piwi protein suggests mechanisms for sirna recognition and slicer activity
    • Parker J, Roe S, Barford D. (2004) Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity. EMBO J 23: 4727-4737.
    • (2004) EMBO J , vol.23 , pp. 37-47
    • Parker, J.1    Roe, S.2    Barford, D.3
  • 78
  • 79
    • 34250017082 scopus 로고    scopus 로고
    • An mrna m7g cap bindinglike motif within human ago2 represses translation
    • Kiriakidou M, Tan G, Lamprinaki S et al. (2007) An mRNA m7G cap bindinglike motif within human Ago2 represses translation. Cell 129: 1141-1151.
    • (2007) Cell , vol.129 , pp. 11-51
    • Kiriakidou, M.1    Tan, G.2    Lamprinaki, S.3
  • 80
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some micrornas downregulate large numbers of target mrnas
    • Lim L, Lau N, Garrett-Engele P et al. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433:769-773.
    • (2005) Nature , vol.433 , pp. 7-73
    • Lim, L.1    Lau, N.2    Garrett-Engele, P.3
  • 81
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of micrornas in vivo with ‘antagomirs’
    • Krutzfeldt J, Rajewsky N, Braich R et al. (2005) Silencing of microRNAs in vivo with ‘antagomirs’. Nature 438: 685-689.
    • (2005) Nature , vol.438 , pp. 68-69
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 82
    • 18244385475 scopus 로고    scopus 로고
    • Micrornas regulate brain morphogenesis in zebrafish
    • Giraldez A, Cinalli R, Glasner M et al. (2005) MicroRNAs regulate brain morphogenesis in zebrafish. Science 308: 833-838.
    • (2005) Science , vol.308 , pp. 83-88
    • Giraldez, A.1    Cinalli, R.2    Glasner, M.3
  • 83
    • 33645124258 scopus 로고    scopus 로고
    • Zebrafish mir-430 promotes deadenylation and clearance of maternal mrnas
    • Giraldez A, Mishima Y, Rihel J et al. (2006) Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science 312: 75-79.
    • (2006) Science , vol.312 , pp. 7-9
    • Giraldez, A.1    Mishima, Y.2    Rihel, J.3
  • 84
    • 33746502166 scopus 로고    scopus 로고
    • A distinct small rna pathway silences selfish genetic elements in the germline
    • Vagin V, Sigova A, Li C et al. (2006) A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313: 320-324.
    • (2006) Science , vol.313 , pp. 32-34
    • Vagin, V.1    Sigova, A.2    Li, C.3
  • 85
    • 33947720638 scopus 로고    scopus 로고
    • Miwi2 is essential for spermatogenesis and repression of transposons in the mouse male germline
    • Carmell M, Girard A, van de Kant H et al. (2007) MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell 12: 503-514.
    • (2007) Dev Cell , vol.12 , pp. 5-14
    • Carmell, M.1    Girard, A.2    Van De Kant, H.3
  • 86
    • 10244243802 scopus 로고    scopus 로고
    • Evidence that microrna precursors, unlike other non-coding rnas, have lower folding free energies than random sequences
    • Bonnet E, Wuyts J, Rouz P, Van de Peer Y. (2004) Evidence that microRNA precursors, unlike other non-coding RNAs, have lower folding free energies than random sequences. Bioinformatics 20: 2911-5917.
    • (2004) Bioinformatics , vol.20 , pp. 591-597
    • Bonnet, E.1    Wuyts, J.2    Rouz, P.3    Van De Peer, Y.4
  • 88
    • 30744468557 scopus 로고    scopus 로고
    • Evidence that mirnas are different from other rnas
    • Zhang B, Pan X, Cox S et al. (2006) Evidence that miRNAs are different from other RNAs. Cell Mol Life Sci 63: 246-254.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 2-54
    • Zhang, B.1    Pan, X.2    Cox, S.3
  • 89
    • 33846437079 scopus 로고    scopus 로고
    • Unique folding of precursor micrornas: Quantitative evidence and implications for de novo identification
    • Ng Kwang Loong S, Mishra S. (2007) Unique folding of precursor microRNAs: quantitative evidence and implications for de novo identification. RNA 13: 170-187.
    • (2007) RNA , vol.13 , pp. 1-87
    • Ng Kwang Loong, S.1    Mishra, S.2
  • 90
    • 33646240072 scopus 로고    scopus 로고
    • Direct evolution of genetic robustness in microrna
    • Borenstein E, Ruppin E. (2006) Direct evolution of genetic robustness in microRNA. Proc Natl Acad Sci USA 103: 6593-6598.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 659-660
    • Borenstein, E.1    Ruppin, E.2
  • 91
    • 0038825783 scopus 로고    scopus 로고
    • Computational identification of drosophila microrna genes
    • Lai E, Tomancak P, Williams R, Rubin G. (2003) Computational identification of Drosophila microRNA genes. Genome Biol 4: R42.
    • (2003) Genome Biol , vol.4 , pp. 42
    • Lai, E.1    Tomancak, P.2    Williams, R.3    Rubin, G.4
  • 92
    • 27844508214 scopus 로고    scopus 로고
    • Identification of clustered micrornas using an ab initio prediction method
    • Sewer A, Paul N, Landgraf P et al. (2005) Identification of clustered microRNAs using an ab initio prediction method. BMC Bioinformatics 6: 267.
    • (2005) BMC Bioinformatics , vol.6 , pp. 267
    • Sewer, A.1    Paul, N.2    Landgraf, P.3
  • 93
    • 40449139010 scopus 로고    scopus 로고
    • The mc-fold and mc-sym pipeline infers rna structure from sequence data
    • Parisien M, Major F. (2008) The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data. Nature 452: 51-55.
    • (2008) Nature , vol.452 , pp. 5-6
    • Parisien, M.1    Major, F.2
  • 94
    • 11844262661 scopus 로고    scopus 로고
    • Phylogenetic shadowing and computational identification of human microrna genes
    • Berezikov E, Guryev V, van de Belt J et al. (2005) Phylogenetic shadowing and computational identification of human microRNA genes. Cell 120: 21-24.
    • (2005) Cell , vol.120 , pp. 2-4
    • Berezikov, E.1    Guryev, V.2    Van De Belt, J.3
  • 95
    • 0027968068 scopus 로고
    • Clustal w: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson J, Higgins D, Gibson T. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673-4680.
    • (1994) Nucleic Acids Res , vol.22 , pp. 46-80
    • Thompson, J.1    Higgins, D.2    Gibson, T.3
  • 96
    • 0033563463 scopus 로고    scopus 로고
    • Automatic detection of conserved base pairingpatterns in rna virus genomes
    • Hofacker I, Stadler P. (1999) Automatic detection of conserved base pairing patterns in RNA virus genomes. Comput Chem 23: 401-414.
    • (1999) Comput Chem , vol.23 , pp. 4-14
    • Hofacker, I.1    Stadler, P.2
  • 97
    • 0037447334 scopus 로고    scopus 로고
    • The micrornas of caenorhabditis elegans
    • Lim L, Lau N, Weinstein E et al. (2003) The microRNAs of Caenorhabditis elegans. Genes Dev 17: 991-1008.
    • (2003) Genes Dev , vol.17 , pp. 991-1008
    • Lim, L.1    Lau, N.2    Weinstein, E.3
  • 98
    • 21844477027 scopus 로고    scopus 로고
    • Human microrna prediction through a probabilistic co-learning model of sequence and structure
    • Nam J, Shin K, Han J et al. (2005) Human microRNA prediction through a probabilistic co-learning model of sequence and structure. Nucleic Acids Res 33: 3570-3581.
    • (2005) Nucleic Acids Res , vol.33 , pp. 35-81
    • Nam, J.1    Shin, K.2    Han, J.3
  • 99
    • 0043123153 scopus 로고    scopus 로고
    • Vienna rna secondary structure server
    • Hofacker I. (2003) Vienna RNA secondary structure server. Nucleic Acids Res 31: 3429-3431.
    • (2003) Nucleic Acids Res , vol.31 , pp. 31-34
    • Hofacker, I.1
  • 100
    • 15244358503 scopus 로고    scopus 로고
    • Systematic discovery of regulatory motifs in human promoters and 3′ utrs by comparison of several mammals
    • Xie X, Lu J, Kulbokas E et al. (2005) Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals. Nature 434: 338-345.
    • (2005) Nature , vol.434 , pp. 338-345
    • Xie, X.1    Lu, J.2    Kulbokas, E.3
  • 101
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microrna target selection in translational repression
    • Doench J, Sharp P. (2004) Specificity of microRNA target selection in translational repression. Genes Dev 18: 504-511.
    • (2004) Genes Dev , vol.18 , pp. 5-11
    • Doench, J.1    Sharp, P.2
  • 103
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often fianked by adenosines, indicates that thousands of human genes are microrna targets
    • Lewis B, Burge C, Bartel D. (2005) Conserved seed pairing, often fianked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.1    Burge, C.2    Bartel, D.3
  • 104
    • 30344447264 scopus 로고    scopus 로고
    • Classification of real and pseudo microrna precursors using local structure-sequence features and support vector machine
    • Xue C, Li F, He T et al. (2005) Classification of real and pseudo microrna precursors using local structure-sequence features and support vector machine. BMC Bioinformatics 6: 310.
    • (2005) BMC Bioinformatics , vol.6 , pp. 310
    • Xue, C.1    Li, F.2    He, T.3
  • 105
    • 33747871855 scopus 로고    scopus 로고
    • Hairpins in a haystack: Recognizing microrna precursors in comparative genomics data
    • Hertel J, Stadler P. (2006) Hairpins in a haystack: recognizing microRNA precursors in comparative genomics data. Bioinformatics 22: e197-202.
    • (2006) Bioinformatics , vol.22 , pp. 197-202
    • Hertel, J.1    Stadler, P.2
  • 106
    • 33846650507 scopus 로고    scopus 로고
    • Reliable prediction of drosha processing sites improves microrna gene prediction
    • Helvik S, Snove O, Saetrom P. (2007) Reliable prediction of Drosha processing sites improves microRNA gene prediction. Bioinformatics 23: 142-149.
    • (2007) Bioinformatics , vol.23 , pp. 14-19
    • Helvik, S.1    Snove, O.2    Saetrom, P.3
  • 107
    • 1542297345 scopus 로고    scopus 로고
    • Computational identification of microrna targets
    • Rajewsky N, Socci N. (2004) Computational identification of microRNA targets. Dev Biol 267: 529-535.
    • (2004) Dev Biol , vol.267 , pp. 5-35
    • Rajewsky, N.1    Socci, N.2
  • 108
    • 0036544755 scopus 로고    scopus 로고
    • Micro rnas are complementary to 3′ utr sequence motifs that mediate negative post-transcriptional regulation
    • Lai E. (2002) Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet 30: 363-364.
    • (2002) Nat Genet , vol.30 , pp. 36-40
    • Lai, E.1
  • 109
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian microrna targets
    • Lewis B, Shih I, Jones-Rhoades M et al. (2003) Prediction of mammalian microRNA targets. Cell 115: 787-798.
    • (2003) Cell , vol.115 , pp. 7-8
    • Lewis, B.1    Shih, I.2    Jones-Rhoades, M.3
  • 110
    • 33748346026 scopus 로고    scopus 로고
    • Perfect seed pairing is not a generally reliable predictor for mirna-target interactions
    • Didiano D, Hobert O. (2006) Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions. Nat Struct Mol Biol 13: 849-851.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 8-51
    • Didiano, D.1    Hobert, O.2
  • 111
    • 34347398567 scopus 로고    scopus 로고
    • Inference of mirna targets using evolutionary conservation and pathway analysis
    • Gaidatzis D, van Nimwegen E, Hausser J, Zavolan M. (2007) Inference of miRNA targets using evolutionary conservation and pathway analysis. BMC Bioinformatics 8: 69.
    • (2007) BMC Bioinformatics , vol.8 , pp. 69
    • Gaidatzis, D.1    Van Nimwegen, E.2    Hausser, J.3    Zavolan, M.4
  • 113
    • 34247258888 scopus 로고    scopus 로고
    • Potent effect of target structure onmicrorna function
    • Long D, Lee R, Williams P et al. (2007) Potent effect of target structure on microRNA function. Nat Struct Mol Biol 14: 287-294.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 2-94
    • Long, D.1    Lee, R.2    Williams, P.3
  • 114
    • 34247382522 scopus 로고    scopus 로고
    • Double-stranded regions are essential design components of potent inhibitors of risc function
    • Vermeulen A, Robertson B, Dalby A et al. (2007) Double-stranded regions are essential design components of potent inhibitors of RISC function. RNA 13: 723-730.
    • (2007) RNA , vol.13 , pp. 7-30
    • Vermeulen, A.1    Robertson, B.2    Dalby, A.3
  • 115
    • 34447102459 scopus 로고    scopus 로고
    • Molecular basis for target rna recognition and cleavage by human risc
    • Ameres S, Martinez J, Schroeder R. (2007) Molecular basis for target RNA recognition and cleavage by human RISC. Cell 130: 101-112.
    • (2007) Cell , vol.130 , pp. 1-12
    • Ameres, S.1    Martinez, J.2    Schroeder, R.3
  • 116
    • 34250805982 scopus 로고    scopus 로고
    • Microrna targeting specificity in mammals: Determinants beyond seed pairing
    • Grimson A, Farh K, Johnston W et al. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105.
    • (2007) Mol Cell , vol.27 , pp. 91-105
    • Grimson, A.1    Farh, K.2    Johnston, W.3
  • 117
    • 33947224690 scopus 로고    scopus 로고
    • Transcripts targeted by the microrna-16 family cooperatively regulate cell cycle progression
    • Linsley P, Schelter J, Burchard J et al. (2007) Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol 27: 2240-2252.
    • (2007) Mol Cell Biol , vol.27 , pp. 22-52
    • Linsley, P.1    Schelter, J.2    Burchard, J.3
  • 118
    • 33745612464 scopus 로고    scopus 로고
    • Widespread sirna “off-target” transcript silencing mediated by seed region sequence complementarity
    • Jackson A, Burchard J, Schelter J et al. (2006) Widespread siRNA “off-target” transcript silencing mediated by seed region sequence complementarity. RNA 12: 1179-1187.
    • (2006) RNA , vol.12 , pp. 11-87
    • Jackson, A.1    Burchard, J.2    Schelter, J.3
  • 119
    • 33749438388 scopus 로고    scopus 로고
    • Designing sirna that distinguish between genes that differ by a single nucleotide
    • Schwarz D, Ding H, Kennington L et al. (2006) Designing siRNA that distinguish between genes that differ by a single nucleotide. PLoS Genet 2: e140.
    • (2006) Plos Genet , vol.140 , pp. 2
    • Schwarz, D.1    Ding, H.2    Kennington, L.3
  • 120
    • 34347393301 scopus 로고    scopus 로고
    • Spatial preferences of microrna targets in 3′ untranslated regions
    • Majoros W, Ohler U. (2007) Spatial preferences of microRNA targets in 3′ untranslated regions. BMC Genomics 8: 152.
    • (2007) BMC Genomics , vol.8 , pp. 152
    • Majoros, W.1    Ohler, U.2
  • 121
    • 28944439309 scopus 로고    scopus 로고
    • Animal micrornas confer robustness to gene expression and have a significant impact on 3′ utr evolution
    • Stark A, Brennecke J, Bushati N et al. (2005) Animal microRNAs confer robustness to gene expression and have a significant impact on 3′ UTR evolution. Cell 123: 1133-1146.
    • (2005) Cell , vol.123 , pp. 11-46
    • Stark, A.1    Brennecke, J.2    Bushati, N.3
  • 122
    • 27344448283 scopus 로고    scopus 로고
    • Human micrornas target a functionally distinct population of genes with at-rich 3′ utrs
    • Robins H, Press W. (2005) Human microRNAs target a functionally distinct population of genes with AT-rich 3′ UTRs. Proc Natl Acad Sci USA 102: 15557-15562.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 155-162
    • Robins, H.1    Press, W.2
  • 123
    • 0842321501 scopus 로고    scopus 로고
    • Microrna targets in drosophila
    • Enright A, John B, Gaul U et al. (2003) MicroRNA targets in Drosophila. Genome Biol 5: R1.
    • (2003) Genome Biol , vol.5 , pp. 1
    • Enright, A.1    John, B.2    Gaul, U.3
  • 124
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microrna target predictions
    • Krek A, Grun D, Poy M et al. (2005) Combinatorial microRNA target predictions. Nat Genet 37: 495-500.
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.3
  • 125
    • 0029937428 scopus 로고    scopus 로고
    • Hidden markov models
    • Eddy S. (1996) Hidden Markov models. Curr Opin Struct Biol 6: 361-365.
    • (1996) Curr Opin Struct Biol , vol.6 , pp. 36-55
    • Eddy, S.1
  • 126
    • 0002287019 scopus 로고    scopus 로고
    • Algorithms and thermodynamics for rna secondary structure prediction. In: Barciszewski j, clark b (eds.)
    • Dordrecht, The Netherlands: Kluwer Academic Publishers
    • Zuker M, Mathews D, Turner D. (1999) Algorithms and thermodynamics for RNA secondary structure prediction. In: Barciszewski J, Clark B (eds.). A Practical Guide in RNA Biochemistry and Biotechnology. Dordrecht, The Netherlands: Kluwer Academic Publishers, pp. 11-43.
    • (1999) A Practical Guide in RNA Biochemistry and Biotechnology , pp. 11-43
    • Zuker, M.1    Mathews, D.2    Turner, D.3
  • 127
    • 34249772381 scopus 로고
    • Fast folding and comparison of rna secondary structures
    • Hofacker I, Fontana W, Stadler P et al. (1994) Fast folding and comparison of RNA secondary structures. Monatsh Chem 125: 167-188.
    • (1994) Monatsh Chem , vol.125 , pp. 1-88
    • Hofacker, I.1    Fontana, W.2    Stadler, P.3
  • 129
    • 33644756532 scopus 로고    scopus 로고
    • A genome-wide map of conserved microrna targets in c. Elegans
    • Lall S, Grü D, Krek A et al. (2006) A genome-wide map of conserved microRNA targets in C. elegans. Curr Biol 16: 460-471.
    • (2006) Curr Biol , vol.16 , pp. 4-71
    • Lall, S.1    Grü, D.2    Krek, A.3
  • 130
    • 4644237189 scopus 로고    scopus 로고
    • Fast and effective prediction of microrna/target duplexes
    • Rehmsmeier M, Steffen P, Hochsmann M, Giegerich R. (2004) Fast and effective prediction of microrNA/target duplexes. RNA 10: 1507-1517.
    • (2004) RNA , vol.10 , pp. 15-17
    • Rehmsmeier, M.1    Steffen, P.2    Hochsmann, M.3    Giegerich, R.4
  • 131
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of rna secondary structure
    • Mathews D, Sabina J, Zuker M, Turner D. (1999) Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J Mol Biol 288: 911-940.
    • (1999) J Mol Biol , vol.288 , pp. 9-40
    • Mathews, D.1    Sabina, J.2    Zuker, M.3    Turner, D.4
  • 132
    • 22244447130 scopus 로고    scopus 로고
    • Weighted sequence motifs as an improved seeding step in microrna target prediction algorithms
    • Saetrom O, Snove O, Saetrom P. (2005) Weighted sequence motifs as an improved seeding step in microRNA target prediction algorithms. RNA 11: 995-1003.
    • (2005) RNA , vol.11 , pp. 995-1003
    • Saetrom, O.1    Snove, O.2    Saetrom, P.3
  • 133
    • 33749645474 scopus 로고    scopus 로고
    • Rhee j et al. (2006) mitarget: Microrna target gene prediction using a support vector machine
    • Kim S, Nam J, Rhee J et al. (2006) miTarget: microRNA target gene prediction using a support vector machine. BMC Bioinformatics 7: 411.
    • BMC Bioinformatics , vol.7 , pp. 411
    • Kim, S.1    Nam, J.2
  • 134
    • 36749005527 scopus 로고    scopus 로고
    • Using expression profiling data to identify human microrna targets
    • Huang J, Babak T, Corson T et al. (2007) Using expression profiling data to identify human microRNA targets. Nat Methods 4: 1045-1049.
    • (2007) Nat Methods , vol.4 , pp. 104-109
    • Huang, J.1    Babak, T.2    Corson, T.3
  • 135
    • 34748821761 scopus 로고    scopus 로고
    • The role of site accessibility in microrna target recognition
    • Kertesz M, Iovino N, Unnerstall U et al. (2007) The role of site accessibility in microRNA target recognition. Nat Genet 39: 1278-1284.
    • (2007) Nat Genet , vol.39 , pp. 12-14
    • Kertesz, M.1    Iovino, N.2    Unnerstall, U.3
  • 136
    • 41349096445 scopus 로고    scopus 로고
    • Gene regulation by transcription factors and micrornas
    • Hobert O. (2008) Gene regulation by transcription factors and microRNAs. Science 319: 1785-1786.
    • (2008) Science , vol.319 , pp. 178-186
    • Hobert, O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.