Presymptomatic Alterations in Amino Acid Metabolism and DNA Methylation in the Cerebellum of a Murine Model of Niemann-Pick Type C Disease

American Journal of Pathology

Volumn 186, Issue 6, 2016, Pages 1582-1597

  Kennedy, Barry E ^a   Hundert, Amos S ^b   Goguen, Donna ^b   Weaver, Ian C G ^b   Karten, Barbara ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLCYTOSINE; AMINO ACID; ASPARAGINE; BINDING PROTEIN; BRANCHED CHAIN AMINO ACID; DNA; DNA METHYLTRANSFERASE 3A; FOLIC ACID; GLUTAMIC ACID; GLUTAMINE;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBON METABOLISM; CEREBELLUM; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PURKINJE CELL; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODEL; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

AMINO ACIDS; ANIMALS; CEREBELLUM; CHROMATIN IMMUNOPRECIPITATION; DISEASE MODELS, ANIMAL; DNA METHYLATION; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; NIEMANN-PICK DISEASE, TYPE C; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84969820295     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2016.02.012     Document Type: Article

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