Regional-specific global cytosine methylation and DNA methyltransferase expression in the adult rat hippocampus

Neuroscience Letters

Volumn 440, Issue 1, 2008, Pages 49-53

  Brown, Shelley E ^a   Weaver, Ian C G ^b   Meaney, Michael J ^b   Szyf, Moshe ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

DNA methylation; DNMT 1; DNMT 3a b; Hippocampus; Maternal care

Indexed keywords

CYTOSINE; DNA METHYLTRANSFERASE; MESSENGER RNA;

AMINO ACID SEQUENCE; ARTICLE; BRAIN REGION; DENTATE GYRUS; HIPPOCAMPUS; METHYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; DNA METHYLATION; FEMALE; GENE EXPRESSION; HIPPOCAMPUS; MALE; RATS; RATS, LONG-EVANS; RNA, MESSENGER; SITE-SPECIFIC DNA METHYLTRANSFERASE (CYTOSINE-SPECIFIC);

EID: 45049086037     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.05.028     Document Type: Article

References (39)

1. Brero A., Easwaran H.P., Nowak D., Grunewald I., Cremer T., Leonhardt H., and Cardoso M.C. Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation. J. Cell Biol. 169 (2005) 733-743
2. Brown S.E., and Szyf M. Epigenetic programming of the ribosomal RNA promoter by MBD3. Mol. Cell Biol. (2007)
3. Cassel S., Revel M.O., Kelche C., and Zwiller J. Expression of the methyl-CpG-binding protein MeCP2 in rat brain. An ontogenetic study. Neurobiol. Dis. 15 (2004) 206-211
4. Cedar H., and Razin A. DNA methylation and development. Biochim. Biophys. Acta 1049 (1990) 1-8
5. Champagne F.A., Francis D.D., Mar A., and Meaney M.J. Variations in maternal care in the rat as a mediating influence for the effects of environment on development. Physiol. Behav. 79 (2003) 359-371
6. Chen T., Hevi S., Gay F., Tsujimoto N., He T., Zhang B., Ueda Y., and Li E. Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nat. Genet. 39 (2007) 391-396
7. Chen W.G., Chang Q., Lin Y., Meissner A., West A.E., Griffith E.C., Jaenisch R., and Greenberg M.E. Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science 302 (2003) 885-889
8. Daumas S., Halley H., Frances B., and Lassalle J.M. Encoding, consolidation, and retrieval of contextual memory: differential involvement of dorsal CA3 and CA1 hippocampal subregions. Learn. Mem. 12 (2005) 375-382
9. Deng J., and Szyf M. Downregulation of DNA (cytosine-5-)methyltransferase is a late event in NGF-induced PC12 cell differentiation. Brain Res. Mol. Brain Res. 71 (1999) 23-31
10. Di Croce L., Raker V.A., Corsaro M., Fazi F., Fanelli M., Faretta M., Fuks F., Lo Coco F., Kouzarides T., Nervi C., Minucci S., and Pelicci P.G. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295 (2002) 1079-1082
11. Espada J., Ballestar E., Santoro R., Fraga M.F., Villar-Garea A., Nemeth A., Lopez-Serra L., Ropero S., Aranda A., Orozco H., Moreno V., Juarranz A., Stockert J.C., Langst G., Grummt I., Bickmore W., and Esteller M. Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells. Nucleic Acids Res. 35 (2007) 2191-2198
12. Gibbons R.J., McDowell T.L., Raman S., O'Rourke D.M., Garrick D., Ayyub H., and Higgs D.R. Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat. Genet. 24 (2000) 368-371
13. Ginsberg S.D., and Che S. Expression profile analysis within the human hippocampus: comparison of CA1 and CA3 pyramidal neurons. J. Comp. Neurol. 487 (2005) 107-118
14. Goto K., Numata M., Komura J.I., Ono T., Bestor T.H., and Kondo H. Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 56 (1994) 39-44
15. Gruenbaum Y., Stein R., Cedar H., and Razin A. Methylation of CpG sequences in eukaryotic DNA. FEBS Lett. 124 (1981) 67-71
16. Jung B.P., Zhang G., Nitsch R., Trogadis J., Nag S., and Eubanks J.H. Differential expression of methyl CpG-binding domain containing factor MBD3 in the developing and adult rat brain. J. Neurobiol. 55 (2003) 220-232
17. Kaplan M.S., and Hinds J.W. Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs. Science 197 (1977) 1092-1094
18. Levenson J.M., Roth T.L., Lubin F.D., Miller C.A., Huang I.C., Desai P., Malone L.M., and Sweatt J.D. Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J. Biol. Chem. 281 (2006) 15763-15773
19. Liang G., Chan M.F., Tomigahara Y., Tsai Y.C., Gonzales F.A., Li E., Laird P.W., and Jones P.A. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol. Cell Biol. 22 (2002) 480-491
20. Lucifero D., La Salle S., Bourc'his D., Martel J., Bestor T.H., and Trasler J.M. Coordinate regulation of DNA methyltransferase expression during oogenesis. BMC Dev. Biol. 7 (2007) 36
21. Miller C.A., and Sweatt J.D. Covalent modification of DNA regulates memory formation. Neuron 53 (2007) 857-869
22. Milutinovic S., Zhuang Q., Niveleau A., and Szyf M. Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes. J. Biol. Chem. 278 (2003) 14985-14995
23. Okano M., Bell D.W., Haber D.A., and Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99 (1999) 247-257
24. Okano M., Xie S., and Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19 (1998) 219-220
25. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1996), Academic Press, San Diego
26. Razin A., and Riggs A.D. DNA methylation and gene function. Science 210 (1980) 604-610
27. Riggs A.D. X inactivation, differentiation, and DNA methylation. Cytogenet. Cell Genet. 14 (1975) 9-25
28. Sapienza C. Parental imprinting of genes. Sci. Am. 263 (1990) 52-60
29. Smallwood A., Esteve P.O., Pradhan S., and Carey M. Functional cooperation between HP1 and DNMT1 mediates gene silencing. Genes Dev. 21 (2007) 1169-1178
30. Steward O. Topographic organization of the projections from the entorhinal area to the hippocampal formation of the rat. J. Comp. Neurol. 167 (1976) 285-314
31. Szyf M., Avraham-Haetzni K., Reifman A., Shlomai J., Kaplan F., Oppenheim A., and Razin A. DNA methylation pattern is determined by the intracellular level of the methylase. Proc. Natl. Acad. Sci. U.S.A. 81 (1984) 3278-3282
32. Torres-Munoz J.E., Van Waveren C., Keegan M.G., Bookman R.J., and Petito C.K. Gene expression profiles in microdissected neurons from human hippocampal subregions. Brain Res. Mol. Brain Res. 127 (2004) 105-114
33. Unterberger A., Andrews S.D., Weaver I.C., and Szyf M. DNA methyltransferase 1 knockdown activates a replication stress checkpoint. Mol. Cell Biol. 26 (2006) 7575-7586
34. Vire E., Brenner C., Deplus R., Blanchon L., Fraga M., Didelot C., Morey L., Van Eynde A., Bernard D., Vanderwinden J.M., Bollen M., Esteller M., Di Croce L., de Launoit Y., and Fuks F. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 439 (2006) 871-874
35. Weaver I.C., Cervoni N., Champagne F.A., D'Alessio A.C., Sharma S., Seckl J.R., Dymov S., Szyf M., and Meaney M.J. Epigenetic programming by maternal behavior. Nat. Neurosci. 7 (2004) 847-854
36. Weaver I.C., Champagne F.A., Brown S.E., Dymov S., Sharma S., Meaney M.J., and Szyf M. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J. Neurosci. 25 (2005) 11045-11054
37. Weaver I.C., Meaney M.J., and Szyf M. Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 3480-3485
38. Yoder J.A., Soman N.S., Verdine G.L., and Bestor T.H. DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe. J. Mol. Biol. 270 (1997) 385-395
39. Yoder J.A., Walsh C.P., and Bestor T.H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13 (1997) 335-340