Quantitative Proteomic Analysis of Niemann-Pick Disease, Type C1 Cerebellum Identifies Protein Biomarkers and Provides Pathological Insight

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Cologna, Stephanie M ^a   Jiang, Xiao Sheng ^a,b   Backlund, Peter S ^a   Cluzeau, Celine V M ^a   Dail, Michelle K ^a   Yanjanin, Nicole M ^a   Siebel, Stephan ^a   Toth, Cynthia L ^a   Jun, Hyun sik ^a   Wassif, Christopher A ^a   Yergey, Alfred L ^a   Porter, Forbes D ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHARGED MULTIVESICULAR BODY PROTEIN 2A; ESCRT PROTEIN; FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 3; FATTY ACID BINDING PROTEIN 5; FATTY ACID BINDING PROTEIN 7; GLUTATHIONE TRANSFERASE ALPHA; MIGLUSTAT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; NPC1 PROTEIN, MOUSE; PROTEIN; PROTEOME;

ADOLESCENT; ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CEREBELLUM; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DETOXIFICATION; FEMALE; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; MALE; MASS SPECTROMETRY; MOUSE; NIEMANN PICK DISEASE; NONHUMAN; OXIDATIVE STRESS; PRESCHOOL CHILD; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN EXPRESSION; PROTEOMICS; SCHOOL CHILD; TWO DIMENSIONAL GEL ELECTROPHORESIS; ANIMAL; BAGG ALBINO MOUSE; CEREBROSPINAL FLUID; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; KNOCKOUT MOUSE; METABOLISM; MIDDLE AGED; PATHOLOGY; PREFRONTAL CORTEX; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EPICOCCUM; MURINAE; MUS;

ALZHEIMER DISEASE; ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CEREBELLUM; CHILD; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MASS SPECTROMETRY; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MIDDLE AGED; NIEMANN-PICK DISEASE, TYPE C; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREFRONTAL CORTEX; PROTEINS; PROTEOME; PROTEOMICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84868124278     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047845     Document Type: Article

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