How Does Hyperphopsphorylation Promote Tau Aggregation and Modulate Filament Structure and Stability?

ACS Chemical Neuroscience

Volumn 7, Issue 5, 2016, Pages 565-575

  Xu, Liang ^a   Zheng, Jie ^b   Margittai, Martin ^c   Nussinov, Ruth ^d,e   Ma, Buyong ^e  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b University of Akron   (United States)

^c UNIVERSITY OF DENVER   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

^e FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

Author keywords

Alzheimer's disease; amyloid; hyperphosphorylation; paired helical filaments; Tau

Indexed keywords

POLYELECTROLYTE; TAU PROTEIN; PROTEIN AGGREGATE; PROTEIN BINDING;

ARTICLE; DEGENERATIVE DISEASE; HUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; CHEMISTRY; INTERMEDIATE FILAMENT; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

HUMANS; INTERMEDIATE FILAMENTS; PHOSPHORYLATION; PROTEIN AGGREGATES; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TAU PROTEINS;

EID: 84969801994     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.5b00294     Document Type: Article

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