-
1
-
-
0033850407
-
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
-
Buee, L., Bussiere, T., Buee-Scherrer, V., Delacourte, A., and Hof, P. R. (2000) Tau protein isoforms, phosphorylation and role in neurodegenerative disorders Brain Res. Rev. 33, 95-130 10.1016/S0165-0173(00)00019-9
-
(2000)
Brain Res. Rev.
, vol.33
, pp. 95-130
-
-
Buee, L.1
Bussiere, T.2
Buee-Scherrer, V.3
Delacourte, A.4
Hof, P.R.5
-
2
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak, H. and Braak, E. (1991) Neuropathological stageing of Alzheimer-related changes Acta Neuropathol. 82, 239-259 10.1007/BF00308809
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
3
-
-
33749150163
-
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
-
Braak, H., Alafuzoff, I., Arzberger, T., Kretzschmar, H., and Del Tredici, K. (2006) Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry Acta Neuropathol. 112, 389-404 10.1007/s00401-006-0127-z
-
(2006)
Acta Neuropathol.
, vol.112
, pp. 389-404
-
-
Braak, H.1
Alafuzoff, I.2
Arzberger, T.3
Kretzschmar, H.4
Del Tredici, K.5
-
4
-
-
84856454190
-
Trans-synaptic spread of tau pathology in vivo
-
Liu, L., Drouet, V., Wu, J. W., Witter, M. P., Small, S. A., Clelland, C., and Duff, K. (2012) Trans-synaptic spread of tau pathology in vivo PLoS One 7, e31302 10.1371/journal.pone.0031302
-
(2012)
PLoS One
, vol.7
, pp. e31302
-
-
Liu, L.1
Drouet, V.2
Wu, J.W.3
Witter, M.P.4
Small, S.A.5
Clelland, C.6
Duff, K.7
-
5
-
-
84857275902
-
Propagation of tau pathology in a model of early Alzheimer's disease
-
de Calignon, A., Polydoro, M., Suarez-Calvet, M., William, C., Adamowicz, D. H., Kopeikina, K. J., Pitstick, R., Sahara, N., Ashe, K. H., Carlson, G. A., Spires-Jones, T. L., and Hyman, B. T. (2012) Propagation of tau pathology in a model of early Alzheimer's disease Neuron 73, 685-697 10.1016/j.neuron.2011.11.033
-
(2012)
Neuron
, vol.73
, pp. 685-697
-
-
De Calignon, A.1
Polydoro, M.2
Suarez-Calvet, M.3
William, C.4
Adamowicz, D.H.5
Kopeikina, K.J.6
Pitstick, R.7
Sahara, N.8
Ashe, K.H.9
Carlson, G.A.10
Spires-Jones, T.L.11
Hyman, B.T.12
-
6
-
-
84903541550
-
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
-
Dujardin, S., Lecolle, K., Caillierez, R., Begard, S., Zommer, N., Lachaud, C., Carrier, S., Dufour, N., Auregan, G., Winderickx, J., Hantraye, P., Deglon, N., Colin, M., and Buee, L. (2014) Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies Acta Neuropathol. Commun. 2, 14 10.1186/2051-5960-2-14
-
(2014)
Acta Neuropathol. Commun.
, vol.2
, pp. 14
-
-
Dujardin, S.1
Lecolle, K.2
Caillierez, R.3
Begard, S.4
Zommer, N.5
Lachaud, C.6
Carrier, S.7
Dufour, N.8
Auregan, G.9
Winderickx, J.10
Hantraye, P.11
Deglon, N.12
Colin, M.13
Buee, L.14
-
7
-
-
84861758226
-
Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
-
Kfoury, N., Holmes, B. B., Jiang, H., Holtzman, D. M., and Diamond, M. I. (2012) Trans-cellular Propagation of Tau Aggregation by Fibrillar Species J. Biol. Chem. 287, 19440-19451 10.1074/jbc.M112.346072
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 19440-19451
-
-
Kfoury, N.1
Holmes, B.B.2
Jiang, H.3
Holtzman, D.M.4
Diamond, M.I.5
-
8
-
-
0026595846
-
Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms
-
Goedert, M., Spillantini, M. G., Cairns, N. J., and Crowther, R. A. (1992) Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms Neuron 8, 159-168 10.1016/0896-6273(92)90117-V
-
(1992)
Neuron
, vol.8
, pp. 159-168
-
-
Goedert, M.1
Spillantini, M.G.2
Cairns, N.J.3
Crowther, R.A.4
-
9
-
-
84877906835
-
Tau pathology and neurodegeneration
-
Spillantini, M. G. and Goedert, M. (2013) Tau pathology and neurodegeneration Lancet Neurol. 12, 609-622 10.1016/S1474-4422(13)70090-5
-
(2013)
Lancet Neurol.
, vol.12
, pp. 609-622
-
-
Spillantini, M.G.1
Goedert, M.2
-
10
-
-
0003986552
-
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease
-
Wischik, C. M., Novak, M., Thogersen, H. C., Edwards, P. C., Runswick, M. J., Jakes, R., Walker, J. E., Milstein, C., Roth, M., and Klug, A. (1988) Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease Proc. Natl. Acad. Sci. U. S. A. 85, 4506-4510 10.1073/pnas.85.12.4506
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 4506-4510
-
-
Wischik, C.M.1
Novak, M.2
Thogersen, H.C.3
Edwards, P.C.4
Runswick, M.J.5
Jakes, R.6
Walker, J.E.7
Milstein, C.8
Roth, M.9
Klug, A.10
-
11
-
-
0027398169
-
Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament
-
Novak, M., Kabat, J., and Wischik, C. M. (1993) Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament EMBO J. 12, 365-370
-
(1993)
EMBO J.
, vol.12
, pp. 365-370
-
-
Novak, M.1
Kabat, J.2
Wischik, C.M.3
-
12
-
-
33646857025
-
The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis
-
von Bergen, M., Barghorn, S., Muller, S. A., Pickhardt, M., Biernat, J., Mandelkow, E. M., Davies, P., Aebi, U., and Mandelkow, E. (2006) The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis Biochemistry 45, 6446-6457 10.1021/bi052530j
-
(2006)
Biochemistry
, vol.45
, pp. 6446-6457
-
-
Von Bergen, M.1
Barghorn, S.2
Muller, S.A.3
Pickhardt, M.4
Biernat, J.5
Mandelkow, E.M.6
Davies, P.7
Aebi, U.8
Mandelkow, E.9
-
13
-
-
0024044195
-
Structural characterization of the core of the paired helical filament of Alzheimer disease
-
Wischik, C. M., Novak, M., Edwards, P. C., Klug, A., Tichelaar, W., and Crowther, R. A. (1988) Structural characterization of the core of the paired helical filament of Alzheimer disease Proc. Natl. Acad. Sci. U. S. A. 85, 4884-4888 10.1073/pnas.85.13.4884
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 4884-4888
-
-
Wischik, C.M.1
Novak, M.2
Edwards, P.C.3
Klug, A.4
Tichelaar, W.5
Crowther, R.A.6
-
14
-
-
84875279731
-
The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush
-
Wegmann, S., Medalsy, I. D., Mandelkow, E., and Muller, D. J. (2013) The fuzzy coat of pathological human Tau fibrils is a two-layered polyelectrolyte brush Proc. Natl. Acad. Sci. U. S. A. 110, E313-321 10.1073/pnas.1212100110
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. E313-E321
-
-
Wegmann, S.1
Medalsy, I.D.2
Mandelkow, E.3
Muller, D.J.4
-
15
-
-
0028027088
-
Domains of tau protein and interactions with microtubules
-
Gustke, N., Trinczek, B., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (1994) Domains of tau protein and interactions with microtubules Biochemistry 33, 9511-9522 10.1021/bi00198a017
-
(1994)
Biochemistry
, vol.33
, pp. 9511-9522
-
-
Gustke, N.1
Trinczek, B.2
Biernat, J.3
Mandelkow, E.M.4
Mandelkow, E.5
-
16
-
-
0037126688
-
Toward a unified scheme for the aggregation of tau into Alzheimer paired helical filaments
-
Barghorn, S. and Mandelkow, E. (2002) Toward a unified scheme for the aggregation of tau into Alzheimer paired helical filaments Biochemistry 41, 14885-14896 10.1021/bi026469j
-
(2002)
Biochemistry
, vol.41
, pp. 14885-14896
-
-
Barghorn, S.1
Mandelkow, E.2
-
17
-
-
33144463940
-
Global hairpin folding of tau in solution
-
Jeganathan, S., von Bergen, M., Brutlach, H., Steinhoff, H. J., and Mandelkow, E. (2006) Global hairpin folding of tau in solution Biochemistry 45, 2283-2293 10.1021/bi0521543
-
(2006)
Biochemistry
, vol.45
, pp. 2283-2293
-
-
Jeganathan, S.1
Von Bergen, M.2
Brutlach, H.3
Steinhoff, H.J.4
Mandelkow, E.5
-
18
-
-
0035930625
-
Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure
-
von Bergen, M., Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2001) Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure J. Biol. Chem. 276, 48165-48174 10.1074/jbc.M105196200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48165-48174
-
-
Von Bergen, M.1
Barghorn, S.2
Li, L.3
Marx, A.4
Biernat, J.5
Mandelkow, E.M.6
Mandelkow, E.7
-
19
-
-
0042307302
-
Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure
-
Berriman, J., Serpell, L. C., Oberg, K. A., Fink, A. L., Goedert, M., and Crowther, R. A. (2003) Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-beta structure Proc. Natl. Acad. Sci. U. S. A. 100, 9034-9038 10.1073/pnas.1530287100
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 9034-9038
-
-
Berriman, J.1
Serpell, L.C.2
Oberg, K.A.3
Fink, A.L.4
Goedert, M.5
Crowther, R.A.6
-
20
-
-
0032428153
-
A nucleated assembly mechanism of Alzheimer paired helical filaments
-
Friedhoff, P., von Bergen, M., Mandelkow, E. M., Davies, P., and Mandelkow, E. (1998) A nucleated assembly mechanism of Alzheimer paired helical filaments Proc. Natl. Acad. Sci. U. S. A. 95, 15712-15717 10.1073/pnas.95.26.15712
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 15712-15717
-
-
Friedhoff, P.1
Von Bergen, M.2
Mandelkow, E.M.3
Davies, P.4
Mandelkow, E.5
-
21
-
-
0029907548
-
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
-
Goedert, M., Jakes, R., Spillantini, M. G., Hasegawa, M., Smith, M. J., and Crowther, R. A. (1996) Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans Nature 383, 550-553 10.1038/383550a0
-
(1996)
Nature
, vol.383
, pp. 550-553
-
-
Goedert, M.1
Jakes, R.2
Spillantini, M.G.3
Hasegawa, M.4
Smith, M.J.5
Crowther, R.A.6
-
22
-
-
0029796168
-
Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction
-
Perez, M., Valpuesta, J. M., Medina, M., Montejo de Garcini, E., and Avila, J. (1996) Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction J. Neurochem. 67, 1183-1190 10.1046/j.1471-4159.1996.67031183.x
-
(1996)
J. Neurochem.
, vol.67
, pp. 1183-1190
-
-
Perez, M.1
Valpuesta, J.M.2
Medina, M.3
Montejo De Garcini, E.4
Avila, J.5
-
23
-
-
0030923223
-
Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease
-
Wilson, D. M. and Binder, L. I. (1997) Free fatty acids stimulate the polymerization of tau and amyloid beta peptides. In vitro evidence for a common effector of pathogenesis in Alzheimer's disease Am. J. Pathol. 150, 2181-2195
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 2181-2195
-
-
Wilson, D.M.1
Binder, L.I.2
-
24
-
-
0033539689
-
Ligand-dependent tau filament formation: implications for Alzheimer's disease progression
-
King, M. E., Ahuja, V., Binder, L. I., and Kuret, J. (1999) Ligand-dependent tau filament formation: implications for Alzheimer's disease progression Biochemistry 38, 14851-14859 10.1021/bi9911839
-
(1999)
Biochemistry
, vol.38
, pp. 14851-14859
-
-
King, M.E.1
Ahuja, V.2
Binder, L.I.3
Kuret, J.4
-
25
-
-
0030590911
-
RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments
-
Kampers, T., Friedhoff, P., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (1996) RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments FEBS Lett. 399, 344-349 10.1016/S0014-5793(96)01386-5
-
(1996)
FEBS Lett.
, vol.399
, pp. 344-349
-
-
Kampers, T.1
Friedhoff, P.2
Biernat, J.3
Mandelkow, E.M.4
Mandelkow, E.5
-
26
-
-
0031439109
-
Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation
-
Hasegawa, M., Crowther, R. A., Jakes, R., and Goedert, M. (1997) Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation J. Biol. Chem. 272, 33118-33124 10.1074/jbc.272.52.33118
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33118-33124
-
-
Hasegawa, M.1
Crowther, R.A.2
Jakes, R.3
Goedert, M.4
-
27
-
-
0026799198
-
The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease
-
Crowther, R. A., Olesen, O. F., Jakes, R., and Goedert, M. (1992) The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease FEBS Lett. 309, 199-202 10.1016/0014-5793(92)81094-3
-
(1992)
FEBS Lett.
, vol.309
, pp. 199-202
-
-
Crowther, R.A.1
Olesen, O.F.2
Jakes, R.3
Goedert, M.4
-
28
-
-
0028121105
-
Assembly of Alzheimer-like filaments from full-length tau protein
-
Crowther, R. A., Olesen, O. F., Smith, M. J., Jakes, R., and Goedert, M. (1994) Assembly of Alzheimer-like filaments from full-length tau protein FEBS Lett. 337, 135-138 10.1016/0014-5793(94)80260-2
-
(1994)
FEBS Lett.
, vol.337
, pp. 135-138
-
-
Crowther, R.A.1
Olesen, O.F.2
Smith, M.J.3
Jakes, R.4
Goedert, M.5
-
29
-
-
0027308924
-
Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
-
Bramblett, G. T., Goedert, M., Jakes, R., Merrick, S. E., Trojanowski, J. Q., and Lee, V. M. (1993) Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding Neuron 10, 1089-1099 10.1016/0896-6273(93)90057-X
-
(1993)
Neuron
, vol.10
, pp. 1089-1099
-
-
Bramblett, G.T.1
Goedert, M.2
Jakes, R.3
Merrick, S.E.4
Trojanowski, J.Q.5
Lee, V.M.6
-
30
-
-
0027338266
-
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding
-
Biernat, J., Gustke, N., Drewes, G., Mandelkow, E. M., and Mandelkow, E. (1993) Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding Neuron 11, 153-163 10.1016/0896-6273(93)90279-Z
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.M.4
Mandelkow, E.5
-
31
-
-
0036830506
-
Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis
-
Li, L., von Bergen, M., Mandelkow, E. M., and Mandelkow, E. (2002) Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis J. Biol. Chem. 277, 41390-41400 10.1074/jbc.M206334200
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41390-41400
-
-
Li, L.1
Von Bergen, M.2
Mandelkow, E.M.3
Mandelkow, E.4
-
32
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
Patrick, G. N., Zukerberg, L., Nikolic, M., de la Monte, S., Dikkes, P., and Tsai, L. H. (1999) Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration Nature 402, 615-622 10.1038/45159
-
(1999)
Nature
, vol.402
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikolic, M.3
De La Monte, S.4
Dikkes, P.5
Tsai, L.H.6
-
33
-
-
0031045396
-
Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques
-
Ginsberg, S. D., Crino, P. B., Lee, V. M., Eberwine, J. H., and Trojanowski, J. Q. (1997) Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques Ann. Neurol. 41, 200-209 10.1002/ana.410410211
-
(1997)
Ann. Neurol.
, vol.41
, pp. 200-209
-
-
Ginsberg, S.D.1
Crino, P.B.2
Lee, V.M.3
Eberwine, J.H.4
Trojanowski, J.Q.5
-
34
-
-
0031719571
-
RNA sequestration to pathological lesions of neurodegenerative diseases
-
Ginsberg, S. D., Galvin, J. E., Chiu, T. S., Lee, V. M., Masliah, E., and Trojanowski, J. Q. (1998) RNA sequestration to pathological lesions of neurodegenerative diseases Acta Neuropathol. 96, 487-494 10.1007/s004010050923
-
(1998)
Acta Neuropathol.
, vol.96
, pp. 487-494
-
-
Ginsberg, S.D.1
Galvin, J.E.2
Chiu, T.S.3
Lee, V.M.4
Masliah, E.5
Trojanowski, J.Q.6
-
35
-
-
78549275132
-
Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease
-
Siddiqua, A. and Margittai, M. (2010) Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease J. Biol. Chem. 285, 37920-37926 10.1074/jbc.M110.185728
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 37920-37926
-
-
Siddiqua, A.1
Margittai, M.2
-
36
-
-
79956223051
-
Variations in Filament Conformation Dictate Seeding Barrier between Three- and Four-Repeat Tau
-
Dinkel, P. D., Siddiqua, A., Huynh, H., Shah, M., and Margittai, M. (2011) Variations in Filament Conformation Dictate Seeding Barrier between Three- and Four-Repeat Tau Biochemistry 50, 4330-4336 10.1021/bi2004685
-
(2011)
Biochemistry
, vol.50
, pp. 4330-4336
-
-
Dinkel, P.D.1
Siddiqua, A.2
Huynh, H.3
Shah, M.4
Margittai, M.5
-
38
-
-
80655128134
-
Understanding the kinetic roles of the inducer heparin and of rod-like protofibrils during amyloid fibril formation by Tau protein
-
Ramachandran, G. and Udgaonkar, J. B. (2011) Understanding the kinetic roles of the inducer heparin and of rod-like protofibrils during amyloid fibril formation by Tau protein J. Biol. Chem. 286, 38948-38959 10.1074/jbc.M111.271874
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 38948-38959
-
-
Ramachandran, G.1
Udgaonkar, J.B.2
-
39
-
-
84863983902
-
Evidence for the existence of a secondary pathway for fibril growth during the aggregation of tau
-
Ramachandran, G. and Udgaonkar, J. B. (2012) Evidence for the existence of a secondary pathway for fibril growth during the aggregation of tau J. Mol. Biol. 421, 296-314 10.1016/j.jmb.2012.01.007
-
(2012)
J. Mol. Biol.
, vol.421
, pp. 296-314
-
-
Ramachandran, G.1
Udgaonkar, J.B.2
-
40
-
-
24144459823
-
Evaluating triggers and enhancers of tau fibrillization
-
Kuret, J., Congdon, E. E., Li, G., Yin, H., Yu, X., and Zhong, Q. (2005) Evaluating triggers and enhancers of tau fibrillization Microsc. Res. Tech. 67, 141-155 10.1002/jemt.20187
-
(2005)
Microsc. Res. Tech.
, vol.67
, pp. 141-155
-
-
Kuret, J.1
Congdon, E.E.2
Li, G.3
Yin, H.4
Yu, X.5
Zhong, Q.6
-
41
-
-
3142699791
-
Template-assisted filament growth by parallel stacking of tau
-
Margittai, M. and Langen, R. (2004) Template-assisted filament growth by parallel stacking of tau Proc. Natl. Acad. Sci. U. S. A. 101, 10278-10283 10.1073/pnas.0401911101
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 10278-10283
-
-
Margittai, M.1
Langen, R.2
-
42
-
-
0020482581
-
A novel reversible thiol-specific spin label: papain active site labeling and inhibition
-
Berliner, L. J., Grunwald, J., Hankovszky, H. O., and Hideg, K. (1982) A novel reversible thiol-specific spin label: papain active site labeling and inhibition Anal. Biochem. 119, 450-455 10.1016/0003-2697(82)90612-1
-
(1982)
Anal. Biochem.
, vol.119
, pp. 450-455
-
-
Berliner, L.J.1
Grunwald, J.2
Hankovszky, H.O.3
Hideg, K.4
-
43
-
-
0034625060
-
Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure
-
von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E. M., and Mandelkow, E. (2000) Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure Proc. Natl. Acad. Sci. U. S. A. 97, 5129-5134 10.1073/pnas.97.10.5129
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5129-5134
-
-
Von Bergen, M.1
Friedhoff, P.2
Biernat, J.3
Heberle, J.4
Mandelkow, E.M.5
Mandelkow, E.6
-
44
-
-
57649128935
-
Fibrils with parallel in-register structure constitute a major class of amyloid fibrils: molecular insights from electron paramagnetic resonance spectroscopy
-
Margittai, M. and Langen, R. (2008) Fibrils with parallel in-register structure constitute a major class of amyloid fibrils: molecular insights from electron paramagnetic resonance spectroscopy Q. Rev. Biophys. 41, 265-297 10.1017/S0033583508004733
-
(2008)
Q. Rev. Biophys.
, vol.41
, pp. 265-297
-
-
Margittai, M.1
Langen, R.2
-
45
-
-
84862551790
-
Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau
-
Siddiqua, A., Luo, Y., Meyer, V., Swanson, M. A., Yu, X., Wei, G., Zheng, J., Eaton, G. R., Ma, B., Nussinov, R., Eaton, S. S., and Margittai, M. (2012) Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau J. Am. Chem. Soc. 134, 10271-10278 10.1021/ja303498q
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 10271-10278
-
-
Siddiqua, A.1
Luo, Y.2
Meyer, V.3
Swanson, M.A.4
Yu, X.5
Wei, G.6
Zheng, J.7
Eaton, G.R.8
Ma, B.9
Nussinov, R.10
Eaton, S.S.11
Margittai, M.12
-
46
-
-
0032516493
-
Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution
-
Friedhoff, P., Schneider, A., Mandelkow, E. M., and Mandelkow, E. (1998) Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution Biochemistry 37, 10223-10230 10.1021/bi980537d
-
(1998)
Biochemistry
, vol.37
, pp. 10223-10230
-
-
Friedhoff, P.1
Schneider, A.2
Mandelkow, E.M.3
Mandelkow, E.4
-
47
-
-
63649160214
-
Conformational diversity of wild-type Tau fibrils specified by templated conformation change
-
Frost, B., Ollesch, J., Wille, H., and Diamond, M. I. (2009) Conformational diversity of wild-type Tau fibrils specified by templated conformation change J. Biol. Chem. 284, 3546-3551 10.1074/jbc.M805627200
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 3546-3551
-
-
Frost, B.1
Ollesch, J.2
Wille, H.3
Diamond, M.I.4
-
48
-
-
84860380323
-
Cross-seeding and conformational selection between three- and four-repeat human Tau proteins
-
Yu, X., Luo, Y., Dinkel, P., Zheng, J., Wei, G., Margittai, M., Nussinov, R., and Ma, B. (2012) Cross-seeding and conformational selection between three- and four-repeat human Tau proteins J. Biol. Chem. 287, 14950-14959 10.1074/jbc.M112.340794
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 14950-14959
-
-
Yu, X.1
Luo, Y.2
Dinkel, P.3
Zheng, J.4
Wei, G.5
Margittai, M.6
Nussinov, R.7
Ma, B.8
-
49
-
-
0030936599
-
Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau
-
Jicha, G. A., Bowser, R., Kazam, I. G., and Davies, P. (1997) Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau J. Neurosci. Res. 48, 128-132 10.1002/(SICI)1097-4547(19970415)48:2<128::AID-JNR5>3.0.CO;2-E
-
(1997)
J. Neurosci. Res.
, vol.48
, pp. 128-132
-
-
Jicha, G.A.1
Bowser, R.2
Kazam, I.G.3
Davies, P.4
-
50
-
-
61349120815
-
Structural polymorphism of 441-residue tau at single residue resolution
-
Mukrasch, M. D., Bibow, S., Korukottu, J., Jeganathan, S., Biernat, J., Griesinger, C., Mandelkow, E., and Zweckstetter, M. (2009) Structural polymorphism of 441-residue tau at single residue resolution PLoS Biol. 7, e34 10.1371/journal.pbio.1000034
-
(2009)
PLoS Biol.
, vol.7
, pp. e34
-
-
Mukrasch, M.D.1
Bibow, S.2
Korukottu, J.3
Jeganathan, S.4
Biernat, J.5
Griesinger, C.6
Mandelkow, E.7
Zweckstetter, M.8
-
51
-
-
84867390250
-
Identification of an aggregation-prone structure of tau
-
Elbaum-Garfinkle, S. and Rhoades, E. (2012) Identification of an aggregation-prone structure of tau J. Am. Chem. Soc. 134, 16607-16613 10.1021/ja305206m
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 16607-16613
-
-
Elbaum-Garfinkle, S.1
Rhoades, E.2
-
52
-
-
33750045702
-
Structural impact of heparin binding to full-length Tau as studied by NMR spectroscopy
-
Sibille, N., Sillen, A., Leroy, A., Wieruszeski, J. M., Mulloy, B., Landrieu, I., and Lippens, G. (2006) Structural impact of heparin binding to full-length Tau as studied by NMR spectroscopy Biochemistry 45, 12560-12572 10.1021/bi060964o
-
(2006)
Biochemistry
, vol.45
, pp. 12560-12572
-
-
Sibille, N.1
Sillen, A.2
Leroy, A.3
Wieruszeski, J.M.4
Mulloy, B.5
Landrieu, I.6
Lippens, G.7
-
53
-
-
34547620334
-
A complex mechanism for inducer mediated tau polymerization
-
Carlson, S. W., Branden, M., Voss, K., Sun, Q., Rankin, C. A., and Gamblin, T. C. (2007) A complex mechanism for inducer mediated tau polymerization Biochemistry 46, 8838-8849 10.1021/bi700403a
-
(2007)
Biochemistry
, vol.46
, pp. 8838-8849
-
-
Carlson, S.W.1
Branden, M.2
Voss, K.3
Sun, Q.4
Rankin, C.A.5
Gamblin, T.C.6
-
54
-
-
84875828405
-
Molecular insights into the reversible formation of tau protein fibrils
-
Luo, Y., Dinkel, P., Yu, X., Margittai, M., Zheng, J., Nussinov, R., Wei, G., and Ma, B. (2013) Molecular insights into the reversible formation of tau protein fibrils Chem. Commun. (Cambridge, U. K.) 49, 3582-3584 10.1039/c3cc00241a
-
(2013)
Chem. Commun. (Cambridge, U. K.)
, vol.49
, pp. 3582-3584
-
-
Luo, Y.1
Dinkel, P.2
Yu, X.3
Margittai, M.4
Zheng, J.5
Nussinov, R.6
Wei, G.7
Ma, B.8
-
55
-
-
0033070197
-
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands
-
Rizzu, P., Van Swieten, J. C., Joosse, M., Hasegawa, M., Stevens, M., Tibben, A., Niermeijer, M. F., Hillebrand, M., Ravid, R., Oostra, B. A., Goedert, M., van Duijn, C. M., and Heutink, P. (1999) High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands Am. J. Hum. Genet. 64, 414-421 10.1086/302256
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 414-421
-
-
Rizzu, P.1
Van Swieten, J.C.2
Joosse, M.3
Hasegawa, M.4
Stevens, M.5
Tibben, A.6
Niermeijer, M.F.7
Hillebrand, M.8
Ravid, R.9
Oostra, B.A.10
Goedert, M.11
Van Duijn, C.M.12
Heutink, P.13
-
56
-
-
84893441729
-
Single mutations in tau modulate the populations of fibril conformers through seed selection
-
Meyer, V., Dinkel, P. D., Luo, Y., Yu, X., Wei, G., Zheng, J., Eaton, G. R., Ma, B., Nussinov, R., Eaton, S. S., and Margittai, M. (2014) Single mutations in tau modulate the populations of fibril conformers through seed selection Angew. Chem., Int. Ed. 53, 1590-1593 10.1002/anie.201308473
-
(2014)
Angew. Chem., Int. Ed.
, vol.53
, pp. 1590-1593
-
-
Meyer, V.1
Dinkel, P.D.2
Luo, Y.3
Yu, X.4
Wei, G.5
Zheng, J.6
Eaton, G.R.7
Ma, B.8
Nussinov, R.9
Eaton, S.S.10
Margittai, M.11
-
57
-
-
84882306577
-
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
-
Holmes, B. B., Devos, S. L., Kfoury, N., Li, M., Jacks, R., Yanamandra, K., Ouidja, M. O., Brodsky, F. M., Marasa, J., Bagchi, D. P., Kotzbauer, P. T., Miller, T. M., Papy-Garcia, D., and Diamond, M. I. (2013) Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds Proc. Natl. Acad. Sci. U. S. A. 110, E3138-3147 10.1073/pnas.1301440110
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. E3138-3147
-
-
Holmes, B.B.1
Devos, S.L.2
Kfoury, N.3
Li, M.4
Jacks, R.5
Yanamandra, K.6
Ouidja, M.O.7
Brodsky, F.M.8
Marasa, J.9
Bagchi, D.P.10
Kotzbauer, P.T.11
Miller, T.M.12
Papy-Garcia, D.13
Diamond, M.I.14
-
58
-
-
0025786506
-
Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease
-
Perry, G., Siedlak, S. L., Richey, P., Kawai, M., Cras, P., Kalaria, R. N., Galloway, P. G., Scardina, J. M., Cordell, B., and Greenberg, B. D. 1991, Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease J. Neurosci. 11, 3679-3683
-
(1991)
J. Neurosci.
, vol.11
, pp. 3679-3683
-
-
Perry, G.1
Siedlak, S.L.2
Richey, P.3
Kawai, M.4
Cras, P.5
Kalaria, R.N.6
Galloway, P.G.7
Scardina, J.M.8
Cordell, B.9
Greenberg, B.D.10
-
59
-
-
0026548436
-
Peripheral distribution of dermatan sulfate proteoglycans (decorin) in amyloid-containing plaques and their presence in neurofibrillary tangles of Alzheimer's disease
-
Snow, A. D., Mar, H., Nochlin, D., Kresse, H., and Wight, T. N. (1992) Peripheral distribution of dermatan sulfate proteoglycans (decorin) in amyloid-containing plaques and their presence in neurofibrillary tangles of Alzheimer's disease J. Histochem. Cytochem. 40, 105-113 10.1177/40.1.1370306
-
(1992)
J. Histochem. Cytochem.
, vol.40
, pp. 105-113
-
-
Snow, A.D.1
Mar, H.2
Nochlin, D.3
Kresse, H.4
Wight, T.N.5
-
60
-
-
0026468915
-
Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease
-
Su, J. H., Cummings, B. J., and Cotman, C. W. (1992) Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease Neuroscience 51, 801-813 10.1016/0306-4522(92)90521-3
-
(1992)
Neuroscience
, vol.51
, pp. 801-813
-
-
Su, J.H.1
Cummings, B.J.2
Cotman, C.W.3
-
61
-
-
0027209456
-
Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease
-
DeWitt, D. A., Silver, J., Canning, D. R., and Perry, G. (1993) Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease Exp. Neurol. 121, 149-152 10.1006/exnr.1993.1081
-
(1993)
Exp. Neurol.
, vol.121
, pp. 149-152
-
-
Dewitt, D.A.1
Silver, J.2
Canning, D.R.3
Perry, G.4
-
63
-
-
36049020231
-
A general model of prion strains and their pathogenicity
-
Collinge, J. and Clarke, A. R. (2007) A general model of prion strains and their pathogenicity Science 318, 930-936 10.1126/science.1138718
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
64
-
-
0142184333
-
RNA molecules stimulate prion protein conversion
-
Deleault, N. R., Lucassen, R. W., and Supattapone, S. (2003) RNA molecules stimulate prion protein conversion Nature 425, 717-720 10.1038/nature01979
-
(2003)
Nature
, vol.425
, pp. 717-720
-
-
Deleault, N.R.1
Lucassen, R.W.2
Supattapone, S.3
-
65
-
-
34547491652
-
Formation of native prions from minimal components in vitro
-
Deleault, N. R., Harris, B. T., Rees, J. R., and Supattapone, S. (2007) Formation of native prions from minimal components in vitro Proc. Natl. Acad. Sci. U. S. A. 104, 9741-9746 10.1073/pnas.0702662104
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 9741-9746
-
-
Deleault, N.R.1
Harris, B.T.2
Rees, J.R.3
Supattapone, S.4
-
66
-
-
22844438894
-
Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions
-
Deleault, N. R., Geoghegan, J. C., Nishina, K., Kascsak, R., Williamson, R. A., and Supattapone, S. (2005) Protease-resistant prion protein amplification reconstituted with partially purified substrates and synthetic polyanions J. Biol. Chem. 280, 26873-26879 10.1074/jbc.M503973200
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26873-26879
-
-
Deleault, N.R.1
Geoghegan, J.C.2
Nishina, K.3
Kascsak, R.4
Williamson, R.A.5
Supattapone, S.6
-
67
-
-
84861848298
-
Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids
-
Deleault, N. R., Piro, J. R., Walsh, D. J., Wang, F., Ma, J., Geoghegan, J. C., and Supattapone, S. (2012) Isolation of phosphatidylethanolamine as a solitary cofactor for prion formation in the absence of nucleic acids Proc. Natl. Acad. Sci. U. S. A. 109, 8546-8551 10.1073/pnas.1204498109
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 8546-8551
-
-
Deleault, N.R.1
Piro, J.R.2
Walsh, D.J.3
Wang, F.4
Ma, J.5
Geoghegan, J.C.6
Supattapone, S.7
-
68
-
-
84863913395
-
Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions
-
Deleault, N. R., Walsh, D. J., Piro, J. R., Wang, F., Wang, X., Ma, J., Rees, J. R., and Supattapone, S. (2012) Cofactor molecules maintain infectious conformation and restrict strain properties in purified prions Proc. Natl. Acad. Sci. U. S. A. 109, E1938-1946 10.1073/pnas.1206999109
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. E1938-1946
-
-
Deleault, N.R.1
Walsh, D.J.2
Piro, J.R.3
Wang, F.4
Wang, X.5
Ma, J.6
Rees, J.R.7
Supattapone, S.8
-
69
-
-
77649213673
-
Generating a prion with bacterially expressed recombinant prion protein
-
Wang, F., Wang, X., Yuan, C. G., and Ma, J. (2010) Generating a prion with bacterially expressed recombinant prion protein Science 327, 1132-1135 10.1126/science.1183748
-
(2010)
Science
, vol.327
, pp. 1132-1135
-
-
Wang, F.1
Wang, X.2
Yuan, C.G.3
Ma, J.4
|