Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin

Brain Research

Volumn 1643, Issue , 2016, Pages 103-112

  Lin, Li ^a   Jin, Zhenzhen ^a   Tan, Huiping ^a   Xu, Qiaoqiao ^a   Peng, Ting ^a,b   Li, He ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

E3 ligase; Huntingtin; Huntington's disease; Ubiquitin proteasome system; Ubiquitination; WWP1

Indexed keywords

GAMMA TUBULIN; HUNTINGTIN; PROTEASOME; PROTEIN AGGREGATE; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE E3 WWP1; UNCLASSIFIED DRUG; HTT PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE; WWP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FLUORESCENCE MICROSCOPY; HUNTINGTON CHOREA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UBIQUITINATION; WESTERN BLOTTING; ANIMAL; BRAIN; CELL CULTURE; CELL SURVIVAL; DISEASE MODEL; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; BRAIN; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HUMANS; HUNTINGTIN PROTEIN; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84966431237     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2016.03.027     Document Type: Article

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