Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65

Biochemical Journal

Volumn 443, Issue 3, 2012, Pages 681-689

  Chow, Wan Ning Vanessa ^a   Luk, Hon Wing ^a   Chan, Ho Yin Edwin ^a   Lau, Kwok Fai ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

FE65; Huntingtin (Htt); Huntington's disease (HD); Protein degradation; Toxicity; Ubiquitination

Indexed keywords

HUNTINGTIN; MUTANT PROTEIN; PROTEASOME; PROTEIN FE65; UBIQUITIN;

ARTICLE; CELL DEATH; CELL LEVEL; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; UBIQUITINATION;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; UBIQUITIN; UBIQUITINATION;

EID: 84860115678     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20112175     Document Type: Article

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