Dysfunction of the ubiquitin ligase Ube3a may be associated with synaptic pathophysiology in a mouse model of Huntington disease

Journal of Biological Chemistry

Volumn 287, Issue 35, 2012, Pages 29949-29957

  Maheshwari, Megha ^a   Samanta, Ananya ^a   Godavarthi, Swetha K ^a   Mukherjee, Rajarshi ^a   Jana, Nihar Ranjan ^a  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ABNORMAL EXPANSION; AMPA-RECEPTOR; COGNITIVE DEFICITS; CORTICAL NEURONS; HUNTINGTIN; HUNTINGTON DISEASE; MOUSE BRAIN; MOUSE MODELS; MUTANT HUNTINGTIN; NEURODEGENERATIVE DISORDERS; NEURONAL PROCESS; PATHOPHYSIOLOGY; POLYGLUTAMINE PROTEINS; SYNAPTIC PLASTICITY; TRANSIENT EXPRESSION; UBIQUITIN LIGASES;

GENE ENCODING; MAMMALS; PROTEINS;

AGGREGATES;

AMPA RECEPTOR; BRAIN PROTEIN; GLUTAMATE RECEPTOR 1; HUNTINGTIN; POLYGLUTAMINE; PROTEIN ARC; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE UBE3A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CORTEX; BRAIN REGION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEFECT; ENZYME DYSFUNCTION; FEMALE; HIPPOCAMPUS; HUNTINGTON CHOREA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MUTANT; NERVE CELL PLASTICITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNAPTOSOME; TRANSGENIC MOUSE;

ANIMALS; CEREBRAL CORTEX; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; HIPPOCAMPUS; HUMANS; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; NUCLEAR PROTEINS; PROTEIN FOLDING; RECEPTORS, AMPA; SYNAPSES; TRINUCLEOTIDE REPEAT EXPANSION; UBIQUITIN-PROTEIN LIGASES;

EID: 84865528947     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.371724     Document Type: Article

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