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Volumn 625, Issue , 2016, Pages 64-69

Epigenetic changes in diabetes

Author keywords

Diabetes; DNA methylation; Epigenetics; HDACs

Indexed keywords

ADVANCED GLYCATION END PRODUCT; DNA; DNA METHYLTRANSFERASE 1; GLUCAGON; GLUCOSE; GLUCOSE TRANSPORTER 4; HISTONE; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; HISTONE H4; HISTONE METHYLTRANSFERASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 1; MICRORNA; MICRORNA 10B; MICRORNA 222; MICRORNA 375; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR PDX 1; UNTRANSLATED RNA;

EID: 84964870432     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2016.04.046     Document Type: Review
Times cited : (48)

References (88)
  • 1
    • 84975856269 scopus 로고    scopus 로고
    • Economic costs of diabetes in the U.S. in 2012
    • American Diabetes A. Economic costs of diabetes in the U.S. in 2012. Diabetes Care 2013, 36(4):1033-1046.
    • (2013) Diabetes Care , vol.36 , Issue.4 , pp. 1033-1046
  • 2
    • 0043244907 scopus 로고    scopus 로고
    • Economic costs of diabetes in the US in 2002
    • Hogan P., et al. Economic costs of diabetes in the US in 2002. Diabetes Care 2003, 26(3):917-932.
    • (2003) Diabetes Care , vol.26 , Issue.3 , pp. 917-932
    • Hogan, P.1
  • 3
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw J.E., Sicree R.A., Zimmet P.Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract. 2010, 87(1):4-14.
    • (2010) Diabetes Res. Clin. Pract. , vol.87 , Issue.1 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 4
    • 84858383401 scopus 로고    scopus 로고
    • Diabetes mellitus and the beta cell: the last ten years
    • Ashcroft F.M., Rorsman P. Diabetes mellitus and the beta cell: the last ten years. Cell 2012, 148(6):1160-1171.
    • (2012) Cell , vol.148 , Issue.6 , pp. 1160-1171
    • Ashcroft, F.M.1    Rorsman, P.2
  • 5
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn J.N., Daly M.J. Genome-wide association studies for common diseases and complex traits. Nat. Rev. Genet. 2005, 6(2):95-108.
    • (2005) Nat. Rev. Genet. , vol.6 , Issue.2 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 6
    • 77951926420 scopus 로고    scopus 로고
    • Etiology of type 1 diabetes
    • Todd J.A. Etiology of type 1 diabetes. Immunity 2010, 32(4):457-467.
    • (2010) Immunity , vol.32 , Issue.4 , pp. 457-467
    • Todd, J.A.1
  • 8
    • 78649842241 scopus 로고    scopus 로고
    • Genomics: type 2 diabetes, and obesity
    • McCarthy M.I. Genomics: type 2 diabetes, and obesity. N. Engl. J. Med. 2010, 363(24):2339-2350.
    • (2010) N. Engl. J. Med. , vol.363 , Issue.24 , pp. 2339-2350
    • McCarthy, M.I.1
  • 9
    • 77955261951 scopus 로고    scopus 로고
    • Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors
    • Kirkpatrick C.L., et al. Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors. PLoS One 2010, 5(6):e11053.
    • (2010) PLoS One , vol.5 , Issue.6 , pp. e11053
    • Kirkpatrick, C.L.1
  • 10
    • 34547702501 scopus 로고    scopus 로고
    • Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
    • Lyssenko V., et al. Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J. Clin. Invest. 2007, 117(8):2155-2163.
    • (2007) J. Clin. Invest. , vol.117 , Issue.8 , pp. 2155-2163
    • Lyssenko, V.1
  • 11
    • 84881218353 scopus 로고    scopus 로고
    • Inactivation of specific beta cell transcription factors in type 2 diabetes
    • Guo S., et al. Inactivation of specific beta cell transcription factors in type 2 diabetes. J. Clin. Invest. 2013, 123(8):3305-3316.
    • (2013) J. Clin. Invest. , vol.123 , Issue.8 , pp. 3305-3316
    • Guo, S.1
  • 12
    • 84901445280 scopus 로고    scopus 로고
    • Beta-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment
    • Halban P.A., et al. beta-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care 2014, 37(6):1751-1758.
    • (2014) Diabetes Care , vol.37 , Issue.6 , pp. 1751-1758
    • Halban, P.A.1
  • 13
    • 84866389264 scopus 로고    scopus 로고
    • Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure
    • Talchai C., et al. Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure. Cell 2012, 150(6):1223-1234.
    • (2012) Cell , vol.150 , Issue.6 , pp. 1223-1234
    • Talchai, C.1
  • 14
    • 9444242665 scopus 로고    scopus 로고
    • Five stages of evolving beta-cell dysfunction during progression to diabetes
    • Weir G.C., Bonner-Weir S. Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 2004, 53(Suppl. 3):S16-S21.
    • (2004) Diabetes , vol.53 , pp. S16-S21
    • Weir, G.C.1    Bonner-Weir, S.2
  • 15
    • 84968707090 scopus 로고    scopus 로고
    • Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications
    • Domingueti C.P., et al. Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications. J. Diabetes Complicat. 2015.
    • (2015) J. Diabetes Complicat.
    • Domingueti, C.P.1
  • 16
    • 85006389536 scopus 로고    scopus 로고
    • Diabetic neuropathies
    • South Dartmouth (MA), L.J. De Groot (Ed.)
    • Vinik A., Casellini C., Nevoret M.L., et al. Diabetic neuropathies. Endotext 2000, South Dartmouth (MA). L.J. De Groot (Ed.).
    • (2000) Endotext
    • Vinik, A.1    Casellini, C.2    Nevoret, M.L.3
  • 17
    • 84960984053 scopus 로고    scopus 로고
    • Diabetes mellitus type 2: a driving force for urological complications
    • Sayyid R.K., Fleshner N.E. Diabetes mellitus type 2: a driving force for urological complications. Trends Endocrinol. Metab. 2016.
    • (2016) Trends Endocrinol. Metab.
    • Sayyid, R.K.1    Fleshner, N.E.2
  • 18
    • 84955603805 scopus 로고    scopus 로고
    • Diabetic retinopathy: animal models, therapies, and perspectives
    • (3789217)
    • Cai X., McGinnis J.F. Diabetic retinopathy: animal models, therapies, and perspectives. J. Diabetes. Res. 2016, 2016. (3789217).
    • (2016) J. Diabetes. Res. , vol.2016
    • Cai, X.1    McGinnis, J.F.2
  • 19
    • 30844471395 scopus 로고    scopus 로고
    • Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?
    • (Sec2)
    • Scheen A.J. Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?. Diabetes Metab. 2005, 31:5S27. (Sec2).
    • (2005) Diabetes Metab. , vol.31 , pp. 5S27
    • Scheen, A.J.1
  • 20
    • 0042535604 scopus 로고    scopus 로고
    • Genetics of insulin resistance
    • Mercado M.M., et al. Genetics of insulin resistance. Curr. Diabetes Rep. 2002, 2(1):83-95.
    • (2002) Curr. Diabetes Rep. , vol.2 , Issue.1 , pp. 83-95
    • Mercado, M.M.1
  • 21
    • 73249133400 scopus 로고    scopus 로고
    • Epigenetics: a molecular link between environmental factors and type 2 diabetes
    • Ling C., Groop L. Epigenetics: a molecular link between environmental factors and type 2 diabetes. Diabetes 2009, 58(12):2718-2725.
    • (2009) Diabetes , vol.58 , Issue.12 , pp. 2718-2725
    • Ling, C.1    Groop, L.2
  • 22
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A. Perceptions of epigenetics. Nature 2007, 447(7143):396-398.
    • (2007) Nature , vol.447 , Issue.7143 , pp. 396-398
    • Bird, A.1
  • 23
    • 84922621952 scopus 로고    scopus 로고
    • Function and information content of DNA methylation
    • Schubeler D. Function and information content of DNA methylation. Nature 2015, 517(7534):321-326.
    • (2015) Nature , vol.517 , Issue.7534 , pp. 321-326
    • Schubeler, D.1
  • 24
    • 79954563768 scopus 로고    scopus 로고
    • Pancreatic beta cell identity is maintained by DNA methylation-mediated repression of Arx
    • Dhawan S., et al. Pancreatic beta cell identity is maintained by DNA methylation-mediated repression of Arx. Dev. Cell 2011, 20(4):419-429.
    • (2011) Dev. Cell , vol.20 , Issue.4 , pp. 419-429
    • Dhawan, S.1
  • 25
    • 84863334811 scopus 로고    scopus 로고
    • Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes
    • Yang B.T., et al. Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes. Mol. Endocrinol. 2012, 26(7):1203-1212.
    • (2012) Mol. Endocrinol. , vol.26 , Issue.7 , pp. 1203-1212
    • Yang, B.T.1
  • 26
    • 84922714378 scopus 로고    scopus 로고
    • Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity
    • Ishikawa K., et al. Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity. PLoS One 2015, 10(2):e0115350.
    • (2015) PLoS One , vol.10 , Issue.2 , pp. e0115350
    • Ishikawa, K.1
  • 27
    • 84857888840 scopus 로고    scopus 로고
    • Reprogramming of pancreatic exocrine cells towards a beta (beta) cell character using Pdx1: Ngn3 and MafA
    • Akinci E., et al. Reprogramming of pancreatic exocrine cells towards a beta (beta) cell character using Pdx1: Ngn3 and MafA. Biochem. J 2012, 442(3):539-550.
    • (2012) Biochem. J , vol.442 , Issue.3 , pp. 539-550
    • Akinci, E.1
  • 28
    • 84883396879 scopus 로고    scopus 로고
    • Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation
    • Katz L.S., Geras-Raaka E., Gershengorn M.C. Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation. Stem Cells Dev. 2013, 22(18):2551-2560.
    • (2013) Stem Cells Dev. , vol.22 , Issue.18 , pp. 2551-2560
    • Katz, L.S.1    Geras-Raaka, E.2    Gershengorn, M.C.3
  • 29
    • 84883425463 scopus 로고    scopus 로고
    • The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation
    • Wang Q., et al. The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation. J. Cell Sci. 2013, 126(Pt 16):3638-3648.
    • (2013) J. Cell Sci. , vol.126 , pp. 3638-3648
    • Wang, Q.1
  • 30
    • 84897452599 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion
    • Dayeh T., et al. Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion. PLoS Genet. 2014, 10(3):e1004160.
    • (2014) PLoS Genet. , vol.10 , Issue.3 , pp. e1004160
    • Dayeh, T.1
  • 31
    • 84912105627 scopus 로고    scopus 로고
    • Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets
    • Olsson A.H. et al. Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets. PLoS Genet. 2014, 10(11):e1004735.
    • (2014) PLoS Genet. , vol.10 , Issue.11 , pp. e1004735
    • Olsson, A.A.1
  • 32
    • 41149172495 scopus 로고    scopus 로고
    • Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
    • Ling C., et al. Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion. Diabetologia 2008, 51(4):615-622.
    • (2008) Diabetologia , vol.51 , Issue.4 , pp. 615-622
    • Ling, C.1
  • 33
    • 78349272755 scopus 로고    scopus 로고
    • Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men
    • Alibegovic A.C., et al. Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men. Am. J. Physiol. Endocrinol. Metab. 2010, 299(5):E752-63.
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.299 , Issue.5 , pp. E752-E763
    • Alibegovic, A.C.1
  • 34
    • 77955205559 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
    • Bell C.G., et al. Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus. BMC Med. Genomics 2010, 3:33.
    • (2010) BMC Med. Genomics , vol.3 , pp. 33
    • Bell, C.G.1
  • 35
    • 58149330673 scopus 로고    scopus 로고
    • G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes
    • Tregouet D.A., et al. G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes. Diabetes 2008, 57(10):2843-2850.
    • (2008) Diabetes , vol.57 , Issue.10 , pp. 2843-2850
    • Tregouet, D.A.1
  • 36
    • 84927145879 scopus 로고    scopus 로고
    • Transcriptional activity of the islet beta cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9
    • Maganti A.V., et al. Transcriptional activity of the islet beta cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9. J. Biol. Chem. 2015, 290(15):9812-9822.
    • (2015) J. Biol. Chem. , vol.290 , Issue.15 , pp. 9812-9822
    • Maganti, A.V.1
  • 37
    • 79957944601 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus
    • Christensen D.P., et al. Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus. Mol. Med. 2011, 17(5-6):378-390.
    • (2011) Mol. Med. , vol.17 , Issue.5-6 , pp. 378-390
    • Christensen, D.P.1
  • 38
    • 58149299735 scopus 로고    scopus 로고
    • Analysis of islet inflammation in human type 1 diabetes
    • Willcox A., et al. Analysis of islet inflammation in human type 1 diabetes. Clin. Exp. Immunol. 2009, 155(2):173-181.
    • (2009) Clin. Exp. Immunol. , vol.155 , Issue.2 , pp. 173-181
    • Willcox, A.1
  • 39
    • 65549170303 scopus 로고    scopus 로고
    • Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
    • Brasacchio D., et al. Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes 2009, 58(5):1229-1236.
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1229-1236
    • Brasacchio, D.1
  • 40
    • 73449092853 scopus 로고    scopus 로고
    • SET7/9 mediated methylation of non-histone proteins in mammalian cells
    • Pradhan S., et al. SET7/9 mediated methylation of non-histone proteins in mammalian cells. Epigenetics 2009, 4(6):383-387.
    • (2009) Epigenetics , vol.4 , Issue.6 , pp. 383-387
    • Pradhan, S.1
  • 41
    • 58149345088 scopus 로고    scopus 로고
    • Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes
    • Miao F., et al. Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes. Diabetes 2008, 57(12):3189-3198.
    • (2008) Diabetes , vol.57 , Issue.12 , pp. 3189-3198
    • Miao, F.1
  • 42
    • 77953860649 scopus 로고    scopus 로고
    • The role of epigenetics in the pathology of diabetic complications
    • Villeneuve L.M., Natarajan R. The role of epigenetics in the pathology of diabetic complications. Am. J. Physiol. Renal Physiol. 2010, 299(1):F14-25.
    • (2010) Am. J. Physiol. Renal Physiol. , vol.299 , Issue.1 , pp. F14-25
    • Villeneuve, L.M.1    Natarajan, R.2
  • 43
    • 79953183375 scopus 로고    scopus 로고
    • Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy
    • Zhong Q., Kowluru R.A. Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy. Diabetes 2011, 60(4):1304-1313.
    • (2011) Diabetes , vol.60 , Issue.4 , pp. 1304-1313
    • Zhong, Q.1    Kowluru, R.A.2
  • 44
    • 84874534208 scopus 로고    scopus 로고
    • Epigenetic modification of Sod2 in the development of diabetic retinopathy and in the metabolic memory: role of histone methylation
    • Zhong Q., Kowluru R.A. Epigenetic modification of Sod2 in the development of diabetic retinopathy and in the metabolic memory: role of histone methylation. Invest. Ophthalmol. Vis. Sci. 2013, 54(1):244-250.
    • (2013) Invest. Ophthalmol. Vis. Sci. , vol.54 , Issue.1 , pp. 244-250
    • Zhong, Q.1    Kowluru, R.A.2
  • 45
    • 0033817811 scopus 로고    scopus 로고
    • Failure of adipocyte differentiation causes type II diabetes mellitus?
    • Danforth E. Failure of adipocyte differentiation causes type II diabetes mellitus?. Nat. Genet. 2000, 26(1):13.
    • (2000) Nat. Genet. , vol.26 , Issue.1 , pp. 13
    • Danforth, E.1
  • 46
    • 78650855058 scopus 로고    scopus 로고
    • In vivo evidence of enhanced di-methylation of histone H3 K4 on upregulated genes in adipose tissue of diabetic db/db mice
    • Fujimoto S., Goda T., Mochizuki K. In vivo evidence of enhanced di-methylation of histone H3 K4 on upregulated genes in adipose tissue of diabetic db/db mice. Biochem. Biophys. Res. Commun. 2011, 404(1):223-227.
    • (2011) Biochem. Biophys. Res. Commun. , vol.404 , Issue.1 , pp. 223-227
    • Fujimoto, S.1    Goda, T.2    Mochizuki, K.3
  • 48
    • 64749111074 scopus 로고    scopus 로고
    • Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
    • Tateishi K., et al. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature 2009, 458(7239):757-761.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 757-761
    • Tateishi, K.1
  • 49
    • 0035212224 scopus 로고    scopus 로고
    • A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions
    • Nerup J., Pociot F., I.S. European Consortium A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions. Am. J. Hum. Genet. 2001, 69(6):1301-1313.
    • (2001) Am. J. Hum. Genet. , vol.69 , Issue.6 , pp. 1301-1313
    • Nerup, J.1    Pociot, F.2
  • 50
    • 9144243533 scopus 로고    scopus 로고
    • Genome-wide search for type 2 diabetes/impaired glucose homeostasis susceptibility genes in the Chinese: significant linkage to chromosome 6q21-q23 and chromosome 1q21-q24
    • Xiang K., et al. Genome-wide search for type 2 diabetes/impaired glucose homeostasis susceptibility genes in the Chinese: significant linkage to chromosome 6q21-q23 and chromosome 1q21-q24. Diabetes 2004, 53(1):228-234.
    • (2004) Diabetes , vol.53 , Issue.1 , pp. 228-234
    • Xiang, K.1
  • 51
    • 0032953097 scopus 로고    scopus 로고
    • Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance-a population-based twin study
    • Poulsen P., et al. Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance-a population-based twin study. Diabetologia 1999, 42(2):139-145.
    • (1999) Diabetologia , vol.42 , Issue.2 , pp. 139-145
    • Poulsen, P.1
  • 53
    • 45549097738 scopus 로고    scopus 로고
    • Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park J.H., et al. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J. Clin. Invest. 2008, 118(6):2316-2324.
    • (2008) J. Clin. Invest. , vol.118 , Issue.6 , pp. 2316-2324
    • Park, J.H.1
  • 54
    • 77950624912 scopus 로고    scopus 로고
    • Epigenetic mechanisms in the development of type 2 diabetes
    • Pinney S.E., Simmons R.A. Epigenetic mechanisms in the development of type 2 diabetes. Trends Endocrinol. Metab. 2010, 21(4):223-229.
    • (2010) Trends Endocrinol. Metab. , vol.21 , Issue.4 , pp. 223-229
    • Pinney, S.E.1    Simmons, R.A.2
  • 55
    • 45549101233 scopus 로고    scopus 로고
    • Histone code modifications repress glucose transporter 4 expression in the intrauterine growth-restricted offspring
    • Raychaudhuri N., et al. Histone code modifications repress glucose transporter 4 expression in the intrauterine growth-restricted offspring. J. Biol. Chem. 2008, 283(20):13611-13626.
    • (2008) J. Biol. Chem. , vol.283 , Issue.20 , pp. 13611-13626
    • Raychaudhuri, N.1
  • 56
    • 0038820063 scopus 로고    scopus 로고
    • Glucose regulates insulin gene transcription by hyperacetylation of histone h4
    • Mosley A.L., Ozcan S. Glucose regulates insulin gene transcription by hyperacetylation of histone h4. J. Biol. Chem. 2003, 278(22):19660-19666.
    • (2003) J. Biol. Chem. , vol.278 , Issue.22 , pp. 19660-19666
    • Mosley, A.L.1    Ozcan, S.2
  • 57
    • 4544233448 scopus 로고    scopus 로고
    • Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1
    • Mosley A.L., Corbett J.A., Ozcan S. Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1. Mol. Endocrinol. 2004, 18(9):2279-2290.
    • (2004) Mol. Endocrinol. , vol.18 , Issue.9 , pp. 2279-2290
    • Mosley, A.L.1    Corbett, J.A.2    Ozcan, S.3
  • 58
    • 11144237178 scopus 로고    scopus 로고
    • The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose
    • Mosley A.L., Ozcan S. The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose. J. Biol. Chem. 2004, 279(52):54241-54242.
    • (2004) J. Biol. Chem. , vol.279 , Issue.52 , pp. 54241-54242
    • Mosley, A.L.1    Ozcan, S.2
  • 59
    • 63249112026 scopus 로고    scopus 로고
    • Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes
    • Deering T.G., et al. Methyltransferase Set7/9 maintains transcription and euchromatin structure at islet-enriched genes. Diabetes 2009, 58(1):185-193.
    • (2009) Diabetes , vol.58 , Issue.1 , pp. 185-193
    • Deering, T.G.1
  • 60
    • 2442589581 scopus 로고    scopus 로고
    • Stimulation of glucose uptake in muscle cells by prolonged treatment with scriptide: a histone deacetylase inhibitor
    • Takigawa-Imamura H., et al. Stimulation of glucose uptake in muscle cells by prolonged treatment with scriptide: a histone deacetylase inhibitor. Biosci. Biotechnol. Biochem. 2003, 67(7):1499-1506.
    • (2003) Biosci. Biotechnol. Biochem. , vol.67 , Issue.7 , pp. 1499-1506
    • Takigawa-Imamura, H.1
  • 61
    • 42449161465 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5
    • McGee S.L., et al. AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5. Diabetes 2008, 57(4):860-867.
    • (2008) Diabetes , vol.57 , Issue.4 , pp. 860-867
    • McGee, S.L.1
  • 62
    • 0035480033 scopus 로고    scopus 로고
    • Control of muscle development by dueling HATs and HDACs
    • McKinsey T.A., Zhang C.L., Olson E.N. Control of muscle development by dueling HATs and HDACs. Curr. Opin. Genet. Dev. 2001, 11(5):497-504.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , Issue.5 , pp. 497-504
    • McKinsey, T.A.1    Zhang, C.L.2    Olson, E.N.3
  • 63
    • 43149104404 scopus 로고    scopus 로고
    • GLUT4 enhancer factor (GEF) interacts with MEF2A and HDAC5 to regulate the GLUT4 promoter in adipocytes
    • Sparling D.P., et al. GLUT4 enhancer factor (GEF) interacts with MEF2A and HDAC5 to regulate the GLUT4 promoter in adipocytes. J. Biol. Chem. 2008, 283(12):7429-7437.
    • (2008) J. Biol. Chem. , vol.283 , Issue.12 , pp. 7429-7437
    • Sparling, D.P.1
  • 64
    • 0034687741 scopus 로고    scopus 로고
    • Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5
    • McKinsey T.A., Zhang C.L., Olson E.N. Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5. Proc. Natl. Acad. Sci. U. S. A. 2000, 97(26):14400-14405.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.26 , pp. 14400-14405
    • McKinsey, T.A.1    Zhang, C.L.2    Olson, E.N.3
  • 65
    • 2342599054 scopus 로고    scopus 로고
    • Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle
    • McGee S.L., Hargreaves M. Exercise and myocyte enhancer factor 2 regulation in human skeletal muscle. Diabetes 2004, 53(5):1208-1214.
    • (2004) Diabetes , vol.53 , Issue.5 , pp. 1208-1214
    • McGee, S.L.1    Hargreaves, M.2
  • 66
    • 0035957375 scopus 로고    scopus 로고
    • Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
    • Michael L.F., et al. Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc. Natl. Acad. Sci. U. S. A. 2001, 98(7):3820-3825.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , Issue.7 , pp. 3820-3825
    • Michael, L.F.1
  • 67
    • 34447511610 scopus 로고    scopus 로고
    • Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation
    • Crunkhorn S., et al. Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. J. Biol. Chem. 2007, 282(21):15439-15450.
    • (2007) J. Biol. Chem. , vol.282 , Issue.21 , pp. 15439-15450
    • Crunkhorn, S.1
  • 68
    • 13844272212 scopus 로고    scopus 로고
    • Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation
    • Kaiser C., James S.R. Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation. BMC Biol. 2004, 2:23.
    • (2004) BMC Biol. , vol.2 , pp. 23
    • Kaiser, C.1    James, S.R.2
  • 69
    • 84864389693 scopus 로고    scopus 로고
    • Acetylation of retinal histones in diabetes increases inflammatory proteins: effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC)
    • Kadiyala C.S., et al. Acetylation of retinal histones in diabetes increases inflammatory proteins: effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC). J. Biol. Chem. 2012, 287(31):25869-25880.
    • (2012) J. Biol. Chem. , vol.287 , Issue.31 , pp. 25869-25880
    • Kadiyala, C.S.1
  • 70
    • 2342423022 scopus 로고    scopus 로고
    • In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions
    • Miao F., et al. In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J. Biol. Chem. 2004, 279(17):18091-18097.
    • (2004) J. Biol. Chem. , vol.279 , Issue.17 , pp. 18091-18097
    • Miao, F.1
  • 71
    • 84960810832 scopus 로고    scopus 로고
    • The intestinal immune system in obesity and insulin resistance
    • Winer D.A., et al. The intestinal immune system in obesity and insulin resistance. Cell Metab. 2016, 23(3):413-426.
    • (2016) Cell Metab. , vol.23 , Issue.3 , pp. 413-426
    • Winer, D.A.1
  • 72
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
    • Hotamisligil G.S., Shargill N.S., Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993, 259(5091):87-91.
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 73
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky J.M., Glass C.K. Macrophages, inflammation, and insulin resistance. Annu. Rev. Physiol. 2010, 72:219-246.
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 74
    • 33645982255 scopus 로고    scopus 로고
    • From mice to men: insights into the insulin resistance syndromes
    • Biddinger S.B., Kahn C.R. From mice to men: insights into the insulin resistance syndromes. Annu. Rev. Physiol. 2006, 68:123-158.
    • (2006) Annu. Rev. Physiol. , vol.68 , pp. 123-158
    • Biddinger, S.B.1    Kahn, C.R.2
  • 75
    • 79954602833 scopus 로고    scopus 로고
    • Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin
    • Yun J.M., Jialal I., Devaraj S. Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin. J. Nutr. Biochem. 2011, 22(5):450-458.
    • (2011) J. Nutr. Biochem. , vol.22 , Issue.5 , pp. 450-458
    • Yun, J.M.1    Jialal, I.2    Devaraj, S.3
  • 76
    • 69249226353 scopus 로고    scopus 로고
    • Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions
    • Perrone L., et al. Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions. J. Cell. Physiol. 2009, 221(1):262-272.
    • (2009) J. Cell. Physiol. , vol.221 , Issue.1 , pp. 262-272
    • Perrone, L.1
  • 77
    • 77955896784 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase protects the retina from ischemic injury
    • Crosson C.E., et al. Inhibition of histone deacetylase protects the retina from ischemic injury. Invest. Ophthalmol. Vis. Sci. 2010, 51(7):3639-3645.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , Issue.7 , pp. 3639-3645
    • Crosson, C.E.1
  • 78
    • 79959994999 scopus 로고    scopus 로고
    • Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice
    • Patel T., et al. Chromatin remodeling resets the immune system to protect against autoimmune diabetes in mice. Immunol. Cell Biol. 2011, 89(5):640-649.
    • (2011) Immunol. Cell Biol. , vol.89 , Issue.5 , pp. 640-649
    • Patel, T.1
  • 79
    • 84869106554 scopus 로고    scopus 로고
    • Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue
    • Galmozzi A., et al. Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue. Diabetes 2013, 62(3):732-742.
    • (2013) Diabetes , vol.62 , Issue.3 , pp. 732-742
    • Galmozzi, A.1
  • 80
    • 84962191103 scopus 로고    scopus 로고
    • Beta-cell MicroRNAs: small but powerful
    • Filios S.R., Shalev A. Beta-cell MicroRNAs: small but powerful. Diabetes 2015, 64(11):3631-3644.
    • (2015) Diabetes , vol.64 , Issue.11 , pp. 3631-3644
    • Filios, S.R.1    Shalev, A.2
  • 81
    • 76249119007 scopus 로고    scopus 로고
    • Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
    • Melton C., Judson R.L., Blelloch R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 2010, 463(7281):621-626.
    • (2010) Nature , vol.463 , Issue.7281 , pp. 621-626
    • Melton, C.1    Judson, R.L.2    Blelloch, R.3
  • 83
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: contributions of translational repression and mRNA decay
    • Huntzinger E., Izaurralde E. Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat. Rev. Genet. 2011, 12(2):99-110.
    • (2011) Nat. Rev. Genet. , vol.12 , Issue.2 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 84
    • 84865581182 scopus 로고    scopus 로고
    • Emerging roles of non-coding RNAs in pancreatic beta-cell function and dysfunction
    • Guay C., et al. Emerging roles of non-coding RNAs in pancreatic beta-cell function and dysfunction. Diabetes Obes. Metab. 2012, 14(Suppl. 3):12-21.
    • (2012) Diabetes Obes. Metab. , vol.14 , pp. 12-21
    • Guay, C.1
  • 85
    • 77952099464 scopus 로고    scopus 로고
    • Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes
    • Herrera B.M., et al. Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes. Diabetologia 2010, 53(6):1099-1109.
    • (2010) Diabetologia , vol.53 , Issue.6 , pp. 1099-1109
    • Herrera, B.M.1
  • 86
    • 71349083569 scopus 로고    scopus 로고
    • MicroRNA-342: microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients
    • Hezova R., et al. microRNA-342: microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients. Cell. Immunol. 2010, 260(2):70-74.
    • (2010) Cell. Immunol. , vol.260 , Issue.2 , pp. 70-74
    • Hezova, R.1
  • 87
    • 9144270691 scopus 로고    scopus 로고
    • A pancreatic islet-specific microRNA regulates insulin secretion
    • Poy M.N., et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 2004, 432(7014):226-230.
    • (2004) Nature , vol.432 , Issue.7014 , pp. 226-230
    • Poy, M.N.1
  • 88
    • 84883793279 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
    • Xu G., et al. Thioredoxin-interacting protein regulates insulin transcription through microRNA-204. Nat. Med. 2013, 19(9):1141-1146.
    • (2013) Nat. Med. , vol.19 , Issue.9 , pp. 1141-1146
    • Xu, G.1


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