Acetylation of retinal histones in diabetes increases inflammatory proteins: Effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC)

Journal of Biological Chemistry

Volumn 287, Issue 31, 2012, Pages 25869-25880

  Kadiyala, Chandra Sekhar Rao ^a,d   Zheng, Ling ^c   Du, Yunpeng ^a   Yohannes, Elizabeth ^a   Kao, Hung Ying ^b   Miyagi, Masaru ^a,b   Kern, Timothy S ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c WUHAN UNIVERSITY   (China)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE; DIABETIC RATS; DIABETIC RETINOPATHY; GLUCOSE LEVEL; HISTONE ACETYLATION; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASE INHIBITOR; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; MINOCYCLINE; PROINFLAMMATORY; RESVERATROL; UP-REGULATION;

ACETYLATION; EYE PROTECTION; GLUCOSE; OPHTHALMOLOGY; ORGANIC ACIDS;

PROTEINS;

HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; INTERCELLULAR ADHESION MOLECULE 1; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; HISTONE ACETYLATION; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; MOLECULAR PATHOLOGY; MUELLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; WESTERN BLOTTING;

ACETYLATION; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; HISTONE ACETYLTRANSFERASES; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HISTONES; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MINOCYCLINE; MOLECULAR SEQUENCE DATA; NITRIC OXIDE SYNTHASE TYPE II; PEPTIDE FRAGMENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, INBRED LEW; RETINA; TANDEM MASS SPECTROMETRY; TERPENES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA; RATTUS;

EID: 84864389693     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.375204     Document Type: Article

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