The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation

Journal of Cell Science

Volumn 126, Issue 16, 2013, Pages 3638-3648

  Wang, Qiwei ^a,b   Wang, Hai ^a   Sun, Yu ^a   Li, Shi Wu ^a   Donelan, William ^a   Chang, Lung Ji ^a   Jin, Shouguang ^a   Terada, Naohiro ^a   Cheng, Henrique ^c   Reeves, Westley H ^a   Yang, Li Jun ^a,d  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^c LOUISIANA STATE UNIVERSITY   (United States)

^d TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cell reprogramming; Directed differentiation; Hepatic cells; Pancreatic progenitor cells; Type 1 diabetes

Indexed keywords

ACTIN; ALKALINE PHOSPHATASE; GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 3BETA; HEPATOCYTE NUCLEAR FACTOR 6; INSULIN; KRUPPEL LIKE FACTOR 4; MYC PROTEIN; NEUROGENIN 3; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SOX9;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CHROMATIN; CONTROLLED STUDY; ENZYME ACTIVITY; EPIGENETICS; GENE EXPRESSION; INSULIN RELEASE; LIVER CELL; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS PROGENITOR CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROMOTER REGION; RAT; SOMATIC CELL; STEM CELL;

CELL REPROGRAMMING; DIRECTED DIFFERENTIATION; HEPATIC CELLS; PANCREATIC PROGENITOR CELLS; TYPE 1 DIABETES;

ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELLS, CULTURED; DNA METHYLATION; HEPATOCYTES; HOMEODOMAIN PROTEINS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, INBRED NOD; MICE, SCID; PROMOTER REGIONS, GENETIC; RATS; STEM CELLS; TRANS-ACTIVATORS;

EID: 84883425463     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.124925     Document Type: Article

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