Inhibition of class i histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

Diabetes

Volumn 62, Issue 3, 2013, Pages 732-742

  Galmozzi, Andrea ^a   Mitro, Nico ^a   Ferrari, Alessandra ^a   Gers, Elise ^a   Gilardi, Federica ^a   Godio, Cristina ^a   Cermenati, Gaia ^a   Gualerzi, Alice ^a   Donetti, Elena ^a   Rotili, Dante ^a   Valente, Sergio ^b   Guerrini, Uliano ^a   Caruso, Donatella ^a   Mai, Antonello ^c   Saez, Enrique ^b   De Fabiani, Emma ^a   Crestani, Maurizio ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [4 [3 (3 FLUOROPHENYL) 3 OXO 1 PROPENYL] 1 METHYL 1H PYRROL 2 YL]ACRYLOHYDROXAMIC ACID; ENTINOSTAT; GLUCOSE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SUBEROYL ANILIDE HYDROXAMIC ACID; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOSE TISSUE; AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY EXPENDITURE; GLUCOSE BLOOD LEVEL; IN VIVO CULTURE; INSULIN BLOOD LEVEL; MALE; METABOLIC DISORDER; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; WEIGHT REDUCTION;

ADIPOSE TISSUE; ANIMALS; ANTI-OBESITY AGENTS; CELL LINE; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; ENERGY METABOLISM; GENE EXPRESSION REGULATION; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE INHIBITORS; HYPOGLYCEMIC AGENTS; MALE; MICE; MICE, MUTANT STRAINS; MITOCHONDRIA, MUSCLE; MOLECULAR TARGETED THERAPY; MUSCLE, SKELETAL; OBESITY; RANDOM ALLOCATION;

EID: 84869106554     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0548     Document Type: Article

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