메뉴 건너뛰기




Volumn 15, Issue 4, 2016, Pages 403-413

Endoplasmic reticulum stress and bipolar disorder - Almost forgotten therapeutic drug targets in the unfolded protein response pathway revisited

Author keywords

Bipolar disorder; Endoplasmic reticulum; Endoplasmic reticulum stress; Lithium; Unfolded protein response; Valproate

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CALCIUM CHANNEL L TYPE; CALCIUM ION; CHAPERONE; CYCLIC AMP BINDING PROTEIN; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN 70; HISTONE DEACETYLASE 1; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; OLANZAPINE; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE; TUNICAMYCIN; VALPROIC ACID; X BOX BINDING PROTEIN 1; TRANQUILIZER;

EID: 84964048198     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527315666160321104613     Document Type: Article
Times cited : (17)

References (116)
  • 1
    • 84886558492 scopus 로고    scopus 로고
    • Suicidal ideation and suicide attempts in children and adolescents with bipolar disorder: A systematic review of prevalence and incidence rates, correlates, and targeted interventions
    • Hauser M, Galling B, Correll CU. Suicidal ideation and suicide attempts in children and adolescents with bipolar disorder: a systematic review of prevalence and incidence rates, correlates, and targeted interventions. Bipolar Disord 2013; 15(5): 507-23.
    • (2013) Bipolar Disord , vol.15 , Issue.5 , pp. 507-523
    • Hauser, M.1    Galling, B.2    Correll, C.U.3
  • 4
    • 33947099865 scopus 로고    scopus 로고
    • Biphasic course in bipolar II outpatients: Prevalence and clinical correlates of a cyclic pattern described by Baillarger and Falret in hospitalised patients in 1854
    • Benazzi F, Akiskal HS. Biphasic course in bipolar II outpatients: prevalence and clinical correlates of a cyclic pattern described by Baillarger and Falret in hospitalised patients in 1854. J Affect Disord 2006; 96(3): 183-7.
    • (2006) J Affect Disord , vol.96 , Issue.3 , pp. 183-187
    • Benazzi, F.1    Akiskal, H.S.2
  • 6
    • 79958009147 scopus 로고    scopus 로고
    • Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder
    • Abdolmaleky HM, Yaqubi S, Papageorgis P, et al. Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder. Schizophr Res 2011; 129(2-3): 183-90.
    • (2011) Schizophr Res , vol.129 , Issue.2-3 , pp. 183-190
    • Abdolmaleky, H.M.1    Yaqubi, S.2    Papageorgis, P.3
  • 7
    • 79958714505 scopus 로고    scopus 로고
    • Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder
    • Ghadirivasfi M, Nohesara S, Ahmadkhaniha HR, et al. Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 2011; 156(5): 536-45.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 , Issue.5 , pp. 536-545
    • Ghadirivasfi, M.1    Nohesara, S.2    Ahmadkhaniha, H.R.3
  • 8
    • 80053988998 scopus 로고    scopus 로고
    • DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder
    • Nohesara S, Ghadirivasfi M, Mostafavi S, et al. DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder. J Psychiatr Res 2011; 45(11): 1432-8.
    • (2011) J Psychiatr Res , vol.45 , Issue.11 , pp. 1432-1438
    • Nohesara, S.1    Ghadirivasfi, M.2    Mostafavi, S.3
  • 9
    • 33750244045 scopus 로고    scopus 로고
    • Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder
    • Abdolmaleky HM, Cheng KH, Faraone SV, et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum Mol Genet 2006; 15(21): 3132-45.
    • (2006) Hum Mol Genet , vol.15 , Issue.21 , pp. 3132-3145
    • Abdolmaleky, H.M.1    Cheng, K.H.2    Faraone, S.V.3
  • 10
    • 20144373163 scopus 로고    scopus 로고
    • Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: A preliminary report
    • Abdolmaleky HM, Cheng KH, Russo A, et al. Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report. Am J Med Genet B Neuropsychiatr Genet 2005; 134B(1): 60-6.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.134 B , Issue.1 , pp. 60-66
    • Abdolmaleky, H.M.1    Cheng, K.H.2    Russo, A.3
  • 11
    • 2142814375 scopus 로고    scopus 로고
    • Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation
    • Abdolmaleky HM, Smith CL, Faraone SV, et al. Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation. Am J Med Genet B Neuropsychiatr Genet 2004; 127B(1): 51-9.
    • (2004) Am J Med Genet B Neuropsychiatr Genet , vol.127 B , Issue.1 , pp. 51-59
    • Abdolmaleky, H.M.1    Smith, C.L.2    Faraone, S.V.3
  • 12
    • 34848862423 scopus 로고    scopus 로고
    • Association analysis of HSP90B1 with bipolar disorder
    • Kakiuchi C, Ishiwata M, Nanko S, et al. Association analysis of HSP90B1 with bipolar disorder. J Hum Genet 2007; 52(10): 794-803.
    • (2007) J Hum Genet , vol.52 , Issue.10 , pp. 794-803
    • Kakiuchi, C.1    Ishiwata, M.2    Nanko, S.3
  • 13
    • 0141730405 scopus 로고    scopus 로고
    • Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder
    • Kakiuchi C, Iwamoto K, Ishiwata M, et al. Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder. Nat Genet 2003; 35(2): 171-5.
    • (2003) Nat Genet , vol.35 , Issue.2 , pp. 171-175
    • Kakiuchi, C.1    Iwamoto, K.2    Ishiwata, M.3
  • 14
    • 0033050865 scopus 로고    scopus 로고
    • Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78
    • Wang JF, Bown C, Young LT. Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78. Mol Pharmacol 1999; 55(3): 521-7.
    • (1999) Mol Pharmacol , vol.55 , Issue.3 , pp. 521-527
    • Wang, J.F.1    Bown, C.2    Young, L.T.3
  • 15
    • 47949099916 scopus 로고    scopus 로고
    • From endoplasmic-reticulum stress to the inflammatory response
    • Zhang K, Kaufman RJ. From endoplasmic-reticulum stress to the inflammatory response. Nature 2008; 454(7203): 455-62.
    • (2008) Nature , vol.454 , Issue.7203 , pp. 455-462
    • Zhang, K.1    Kaufman, R.J.2
  • 16
    • 0030613521 scopus 로고    scopus 로고
    • Transient Ca2+ changes in endothelial cells induced by low doses of reactive oxygen species: Role of hydrogen peroxide
    • Volk T, Hensel M, Kox WJ. Transient Ca2+ changes in endothelial cells induced by low doses of reactive oxygen species: role of hydrogen peroxide. Mol Cell Biochem 1997; 171(1-2): 11-21.
    • (1997) Mol Cell Biochem , vol.171 , Issue.1-2 , pp. 11-21
    • Volk, T.1    Hensel, M.2    Kox, W.J.3
  • 17
    • 79952036205 scopus 로고    scopus 로고
    • Protein misfolding and cellular stress: An overview
    • Gregersen N, Bross P. Protein misfolding and cellular stress: an overview. Methods Mol Biol 2010; 648: 3-23.
    • (2010) Methods Mol Biol , vol.648 , pp. 3-23
    • Gregersen, N.1    Bross, P.2
  • 18
    • 0034643336 scopus 로고    scopus 로고
    • Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
    • Schubert U, Anton LC, Gibbs J, Norbury CC, Yewdell JW, Bennink JR. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 2000; 404(6779): 770-4.
    • (2000) Nature , vol.404 , Issue.6779 , pp. 770-774
    • Schubert, U.1    Anton, L.C.2    Gibbs, J.3    Norbury, C.C.4    Yewdell, J.W.5    Bennink, J.R.6
  • 19
    • 84880425478 scopus 로고    scopus 로고
    • Single-prolonged stress induces endoplasmic reticulum-dependent apoptosis in the hippocampus in a rat model of post-traumatic stress disorder
    • Han F, Yan S, Shi Y. Single-prolonged stress induces endoplasmic reticulum-dependent apoptosis in the hippocampus in a rat model of post-traumatic stress disorder. PLoS One 2013; 8(7): e69340.
    • (2013) PLoS One , vol.8 , Issue.7 , pp. e69340
    • Han, F.1    Yan, S.2    Shi, Y.3
  • 20
    • 84892948203 scopus 로고    scopus 로고
    • Neuronal endoplasmic reticulum stress in axon injury and neurodegeneration
    • Li S, Yang L, Selzer ME, Hu Y. Neuronal endoplasmic reticulum stress in axon injury and neurodegeneration. Ann Neurol 2013; 74(6): 768-777.
    • (2013) Ann Neurol , vol.74 , Issue.6 , pp. 768-777
    • Li, S.1    Yang, L.2    Selzer, M.E.3    Hu, Y.4
  • 21
    • 84872330613 scopus 로고    scopus 로고
    • The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: A differential role of unfolded protein response (UPR) signaling proteins
    • Lakshmanan AP, Harima M, Suzuki K, et al. The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: a differential role of unfolded protein response (UPR) signaling proteins. Int J Biochem Cell Biol 2013; 45(2): 438-47.
    • (2013) Int J Biochem Cell Biol , vol.45 , Issue.2 , pp. 438-447
    • Lakshmanan, A.P.1    Harima, M.2    Suzuki, K.3
  • 22
    • 84859213108 scopus 로고    scopus 로고
    • Metabolic syndrome and acute hyperglycemia are associated with endoplasmic reticulum stress in human mononuclear cells
    • Sage AT, Holtby-Ottenhof S, Shi Y, Damjanovic S, Sharma AM, Werstuck GH. Metabolic syndrome and acute hyperglycemia are associated with endoplasmic reticulum stress in human mononuclear cells. Obesity 2012; 20(4): 748-55.
    • (2012) Obesity , vol.20 , Issue.4 , pp. 748-755
    • Sage, A.T.1    Holtby-Ottenhof, S.2    Shi, Y.3    Damjanovic, S.4    Sharma, A.M.5    Werstuck, G.H.6
  • 23
    • 84897520145 scopus 로고    scopus 로고
    • Pharmacological studies on neurodegenerative diseases focusing on refolding and degradation of unfolded proteins in the endoplasmic reticulum
    • Nomura Y. Pharmacological studies on neurodegenerative diseases focusing on refolding and degradation of unfolded proteins in the endoplasmic reticulum. Yakugaku Zasshi 2014; 134(4): 537-43.
    • (2014) Yakugaku Zasshi , vol.134 , Issue.4 , pp. 537-543
    • Nomura, Y.1
  • 24
    • 84877302055 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and Parkinson’s disease: The role of HRD1 in averting apoptosis in neurodegenerative disease
    • Omura T, Kaneko M, Okuma Y, Matsubara K, Nomura Y. Endoplasmic reticulum stress and Parkinson’s disease: the role of HRD1 in averting apoptosis in neurodegenerative disease. Oxid Med Cell Longev 2013; 2013: 239854.
    • (2013) Oxid Med Cell Longev , vol.2013 , pp. 239854
    • Omura, T.1    Kaneko, M.2    Okuma, Y.3    Matsubara, K.4    Nomura, Y.5
  • 25
    • 84899844505 scopus 로고    scopus 로고
    • Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
    • Valdes P, Mercado G, Vidal RL, et al. Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1. Proc Natl Acad Sci USA 2014; 111(18): 6804-9.
    • (2014) Proc Natl Acad Sci USA , vol.111 , Issue.18 , pp. 6804-6809
    • Valdes, P.1    Mercado, G.2    Vidal, R.L.3
  • 26
    • 84897094564 scopus 로고    scopus 로고
    • Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
    • Hetz C, Mollereau B. Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases. Nat Rev Neurosci 2014; 15(4): 233-49.
    • (2014) Nat Rev Neurosci , vol.15 , Issue.4 , pp. 233-249
    • Hetz, C.1    Mollereau, B.2
  • 28
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007; 8(7): 519-29.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.7 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 29
    • 84863586566 scopus 로고    scopus 로고
    • A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress
    • van Schadewijk A, van’t Wout EF, Stolk J, Hiemstra PS. A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stress. Cell Stress Chaperones 2012; 17(2): 275-9.
    • (2012) Cell Stress Chaperones , vol.17 , Issue.2 , pp. 275-279
    • van Schadewijk, A.1    van’t Wout, E.F.2    Stolk, J.3    Hiemstra, P.S.4
  • 30
    • 84904987624 scopus 로고    scopus 로고
    • Impaired endoplasmic reticulum stress response in bipolar disorder: Cellular evidence of illness progression
    • Pfaffenseller B, Wollenhaupt-Aguiar B, Fries GR, et al. Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression. Int J Neuropsychopharmacol 2014; 17(9): 1453-63.
    • (2014) Int J Neuropsychopharmacol , vol.17 , Issue.9 , pp. 1453-1463
    • Pfaffenseller, B.1    Wollenhaupt-Aguiar, B.2    Fries, G.R.3
  • 31
    • 61949186636 scopus 로고    scopus 로고
    • Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder
    • Hayashi A, Kasahara T, Kametani M, Toyota T, Yoshikawa T, Kato T. Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder. Int J Neuropsychopharmacol 2009; 12(1): 33-43.
    • (2009) Int J Neuropsychopharmacol , vol.12 , Issue.1 , pp. 33-43
    • Hayashi, A.1    Kasahara, T.2    Kametani, M.3    Toyota, T.4    Yoshikawa, T.5    Kato, T.6
  • 32
    • 34250777412 scopus 로고    scopus 로고
    • Impaired endoplasmic reticulum stress response in B-lymphoblasts from patients with bipolar-I disorder
    • So J, Warsh JJ, Li PP. Impaired endoplasmic reticulum stress response in B-lymphoblasts from patients with bipolar-I disorder. Biol Psychiatry 2007; 62(2): 141-7.
    • (2007) Biol Psychiatry , vol.62 , Issue.2 , pp. 141-147
    • So, J.1    Warsh, J.J.2    Li, P.P.3
  • 33
    • 0036105204 scopus 로고    scopus 로고
    • Regulation of ER stress proteins by valproate: Therapeutic implications
    • Bown CD, Wang JF, Chen B, Young LT. Regulation of ER stress proteins by valproate: therapeutic implications. Bipolar Disord 2002; 4(2): 145-51.
    • (2002) Bipolar Disord , vol.4 , Issue.2 , pp. 145-151
    • Bown, C.D.1    Wang, J.F.2    Chen, B.3    Young, L.T.4
  • 34
    • 0033974460 scopus 로고    scopus 로고
    • Increased temporal cortex ER stress proteins in depressed subjects who died by suicide
    • Bown C, Wang JF, MacQueen G, Young LT. Increased temporal cortex ER stress proteins in depressed subjects who died by suicide. Neuropsychopharmacology 2000; 22(3): 327-32.
    • (2000) Neuropsychopharmacology , vol.22 , Issue.3 , pp. 327-332
    • Bown, C.1    Wang, J.F.2    MacQueen, G.3    Young, L.T.4
  • 35
    • 0033845743 scopus 로고    scopus 로고
    • Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells
    • Bown CD, Wang JF, Young LT. Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells. Neuropharmacology 2000; 39(11): 2162-9.
    • (2000) Neuropharmacology , vol.39 , Issue.11 , pp. 2162-2169
    • Bown, C.D.1    Wang, J.F.2    Young, L.T.3
  • 36
    • 0034307061 scopus 로고    scopus 로고
    • Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus
    • Chen B, Wang JF, Young LT. Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus. Biol Psychiatry 2000; 48(7): 658-64.
    • (2000) Biol Psychiatry , vol.48 , Issue.7 , pp. 658-664
    • Chen, B.1    Wang, J.F.2    Young, L.T.3
  • 37
    • 59249087087 scopus 로고    scopus 로고
    • Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94
    • Kakiuchi C, Ishigaki S, Oslowski CM, Fonseca SG, Kato T, Urano F. Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94. PLoS One 2009; 4(1): e4134.
    • (2009) PLoS One , vol.4 , Issue.1 , pp. e4134
    • Kakiuchi, C.1    Ishigaki, S.2    Oslowski, C.M.3    Fonseca, S.G.4    Kato, T.5    Urano, F.6
  • 38
    • 32044462724 scopus 로고    scopus 로고
    • Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells
    • Shao L, Sun X, Xu L, Young LT, Wang JF. Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells. Life Sci 2006; 78(12): 1317-23.
    • (2006) Life Sci , vol.78 , Issue.12 , pp. 1317-1323
    • Shao, L.1    Sun, X.2    Xu, L.3    Young, L.T.4    Wang, J.F.5
  • 39
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 2001; 276(39): 36734-41.
    • (2001) J Biol Chem , vol.276 , Issue.39 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 40
    • 66849109082 scopus 로고    scopus 로고
    • Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis
    • Baumeister P, Dong D, Fu Y, Lee AS. Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis. Mol Cancer Ther 2009; 8(5): 1086-94.
    • (2009) Mol Cancer Ther , vol.8 , Issue.5 , pp. 1086-1094
    • Baumeister, P.1    Dong, D.2    Fu, Y.3    Lee, A.S.4
  • 41
    • 84894355071 scopus 로고    scopus 로고
    • Lithium down-regulates histone deacetylase 1 (HDAC1) and induces degradation of mutant huntingtin
    • Wu S, Zheng SD, Huang HL, et al. Lithium down-regulates histone deacetylase 1 (HDAC1) and induces degradation of mutant huntingtin. J Biol Chem 2013; 288(49): 35500-10.
    • (2013) J Biol Chem , vol.288 , Issue.49 , pp. 35500-35510
    • Wu, S.1    Zheng, S.D.2    Huang, H.L.3
  • 42
    • 16344382201 scopus 로고    scopus 로고
    • Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: Roles of intracellular calcium, GRP78 and Bcl-2
    • Hiroi T, Wei H, Hough C, Leeds P, Chuang DM. Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2. Pharmacogenom J 2005; 5(2): 102-11.
    • (2005) Pharmacogenom J , vol.5 , Issue.2 , pp. 102-111
    • Hiroi, T.1    Wei, H.2    Hough, C.3    Leeds, P.4    Chuang, D.M.5
  • 43
    • 14044261099 scopus 로고    scopus 로고
    • Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3
    • Kim AJ, Shi Y, Austin RC, Werstuck GH. Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. J Cell Sci 2005; 118(Pt 1): 89-99.
    • (2005) J Cell Sci , vol.118 , pp. 89-99
    • Kim, A.J.1    Shi, Y.2    Austin, R.C.3    Werstuck, G.H.4
  • 44
    • 84856702223 scopus 로고    scopus 로고
    • Inhibition of GSK3 by lithium, from single molecules to signaling networks
    • Freland L, Beaulieu JM. Inhibition of GSK3 by lithium, from single molecules to signaling networks. Front Mol Neurosci 2012; 5: 14.
    • (2012) Front Mol Neurosci , vol.5 , pp. 14
    • Freland, L.1    Beaulieu, J.M.2
  • 45
    • 70350172912 scopus 로고    scopus 로고
    • Validating GSK3 as an in vivo target of lithium action
    • O’Brien WT, Klein PS. Validating GSK3 as an in vivo target of lithium action. Biochem Soc Trans 2009; 37(Pt 5): 1133-8.
    • (2009) Biochem Soc Trans , vol.37 , pp. 1133-1138
    • O’Brien, W.T.1    Klein, P.S.2
  • 46
    • 77952139544 scopus 로고    scopus 로고
    • The circadian clock and mood-related behavior
    • Hampp G, Albrecht U. The circadian clock and mood-related behavior. Commun Integr Biol 2008; 1(1): 1-3.
    • (2008) Commun Integr Biol , vol.1 , Issue.1 , pp. 1-3
    • Hampp, G.1    Albrecht, U.2
  • 47
    • 43049116816 scopus 로고    scopus 로고
    • Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood
    • Hampp G, Ripperger JA, Houben T, et al. Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol 2008; 18(9): 678-83.
    • (2008) Curr Biol , vol.18 , Issue.9 , pp. 678-683
    • Hampp, G.1    Ripperger, J.A.2    Houben, T.3
  • 48
    • 84907509651 scopus 로고    scopus 로고
    • A specific role for the REV-ERBalpha-controlled L-Type Voltage-Gated Calcium Channel CaV1.2 in resetting the circadian clock in the late night
    • Schmutz I, Chavan R, Ripperger JA, et al. A specific role for the REV-ERBalpha-controlled L-Type Voltage-Gated Calcium Channel CaV1.2 in resetting the circadian clock in the late night. J Biol Rhythms 2014; 29(4): 288-98.
    • (2014) J Biol Rhythms , vol.29 , Issue.4 , pp. 288-298
    • Schmutz, I.1    Chavan, R.2    Ripperger, J.A.3
  • 49
    • 16344382201 scopus 로고    scopus 로고
    • Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: Roles of intracellular calcium, GRP78 and Bcl-2
    • Hiroi T, Wei H, Hough C, Leeds P, Chuang DM. Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2. Pharmacogenom J 2005; 5(2): 102-11.
    • (2005) Pharmacogenom J , vol.5 , Issue.2 , pp. 102-111
    • Hiroi, T.1    Wei, H.2    Hough, C.3    Leeds, P.4    Chuang, D.M.5
  • 50
    • 84875942000 scopus 로고    scopus 로고
    • Protective effects of lithium: A new look at an old drug with potential antioxidative and antiinflammatory effects in an animal model of sepsis
    • Albayrak A, Halici Z, Polat B, et al. Protective effects of lithium: A new look at an old drug with potential antioxidative and antiinflammatory effects in an animal model of sepsis. Int Immunopharmacol 2013; 16(1): 35-40.
    • (2013) Int Immunopharmacol , vol.16 , Issue.1 , pp. 35-40
    • Albayrak, A.1    Halici, Z.2    Polat, B.3
  • 51
    • 84875958002 scopus 로고    scopus 로고
    • Neuroprotective effects of chronic exposure of SH-SY5Y to low lithium concentration involve glycolysis stimulation, extracellular pyruvate accumulation and resistance to oxidative stress
    • Nciri R, Desmoulin F, Allagui MS, et al. Neuroprotective effects of chronic exposure of SH-SY5Y to low lithium concentration involve glycolysis stimulation, extracellular pyruvate accumulation and resistance to oxidative stress. Int J Neuropsychopharmacol 2013; 16(2): 365-76.
    • (2013) Int J Neuropsychopharmacol , vol.16 , Issue.2 , pp. 365-376
    • Nciri, R.1    Desmoulin, F.2    Allagui, M.S.3
  • 52
    • 78650679896 scopus 로고    scopus 로고
    • Lithium and valproate modulate antioxidant enzymes and prevent ouabaininduced oxidative damage in an animal model of mania
    • Jornada LK, Valvassori SS, Steckert AV, et al. Lithium and valproate modulate antioxidant enzymes and prevent ouabaininduced oxidative damage in an animal model of mania. J Psychiatr Res 2011; 45(2): 162-8.
    • (2011) J Psychiatr Res , vol.45 , Issue.2 , pp. 162-168
    • Jornada, L.K.1    Valvassori, S.S.2    Steckert, A.V.3
  • 53
    • 79961210760 scopus 로고    scopus 로고
    • Lithium protects against oxidative stress-mediated cell death in alpha-synucleinoverexpressing in vitro and in vivo models of Parkinson’s disease
    • Kim YH, Rane A, Lussier S, Andersen JK. Lithium protects against oxidative stress-mediated cell death in alpha-synucleinoverexpressing in vitro and in vivo models of Parkinson’s disease. J Neurosci Res 2011; 89(10): 1666-75.
    • (2011) J Neurosci Res , vol.89 , Issue.10 , pp. 1666-1675
    • Kim, Y.H.1    Rane, A.2    Lussier, S.3    Andersen, J.K.4
  • 54
    • 84913572979 scopus 로고    scopus 로고
    • Peripheral markers of oxidative stress and antioxidative defense in euthymia of bipolar disorder-Gender and obesity effects
    • Bengesser SA, Lackner N, Birner A, et al. Peripheral markers of oxidative stress and antioxidative defense in euthymia of bipolar disorder-Gender and obesity effects. J Affect Disord 2014; 172C: 367-74.
    • (2014) J Affect Disord , vol.172 C , pp. 367-374
    • Bengesser, S.A.1    Lackner, N.2    Birner, A.3
  • 55
    • 84964006412 scopus 로고    scopus 로고
    • Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca regulation in airway smooth muscle (ASM)
    • Delmotte P, Sieck GC. Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca regulation in airway smooth muscle (ASM). Can J Physiol Pharmacol 2014; 25: 1-14.
    • (2014) Can J Physiol Pharmacol , vol.25 , pp. 1-14
    • Delmotte, P.1    Sieck, G.C.2
  • 56
    • 84911481189 scopus 로고    scopus 로고
    • Expression of endoplasmic reticulum stress markers GRP78 and CHOP induced by oxidative stress in blue light-mediated damage of A2Econtaining retinal pigment epithelium cells
    • Feng J, Chen X, Sun X, Wang F, Sun X. Expression of endoplasmic reticulum stress markers GRP78 and CHOP induced by oxidative stress in blue light-mediated damage of A2Econtaining retinal pigment epithelium cells. Ophthalmic Res 2014; 52(4): 224-33.
    • (2014) Ophthalmic Res , vol.52 , Issue.4 , pp. 224-233
    • Feng, J.1    Chen, X.2    Sun, X.3    Wang, F.4    Sun, X.5
  • 57
    • 84913530181 scopus 로고    scopus 로고
    • Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway
    • Lu TH, Su CC, Tang FC, et al. Chloroacetic acid triggers apoptosis in neuronal cells via a reactive oxygen species-induced endoplasmic reticulum stress signaling pathway. Chem Biol Interact 2015; 225: 1-12.
    • (2015) Chem Biol Interact , vol.225 , pp. 1-12
    • Lu, T.H.1    Su, C.C.2    Tang, F.C.3
  • 58
    • 25644434771 scopus 로고    scopus 로고
    • Functional polymorphisms of HSPA5: Possible association with bipolar disorder
    • Kakiuchi C, Ishiwata M, Nanko S, et al. Functional polymorphisms of HSPA5: possible association with bipolar disorder. Biochem Biophys Res Commun 2005; 336(4): 1136-43.
    • (2005) Biochem Biophys Res Commun , vol.336 , Issue.4 , pp. 1136-1143
    • Kakiuchi, C.1    Ishiwata, M.2    Nanko, S.3
  • 59
    • 34548297658 scopus 로고    scopus 로고
    • Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway
    • Matigian N, Windus L, Smith H, et al. Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway. Mol Psychiatry 2007; 12(9): 815-25.
    • (2007) Mol Psychiatry , vol.12 , Issue.9 , pp. 815-825
    • Matigian, N.1    Windus, L.2    Smith, H.3
  • 60
    • 34250777412 scopus 로고    scopus 로고
    • Impaired endoplasmic reticulum stress response in B-lymphoblasts from patients with bipolar-I disorder
    • So J, Warsh JJ, Li PP. Impaired endoplasmic reticulum stress response in B-lymphoblasts from patients with bipolar-I disorder. Biol Psychiatry 2007; 62(2): 141-7.
    • (2007) Biol Psychiatry , vol.62 , Issue.2 , pp. 141-147
    • So, J.1    Warsh, J.J.2    Li, P.P.3
  • 61
    • 35649005969 scopus 로고    scopus 로고
    • Lack of association between endoplasmic reticulum stress response genes and suicidal victims
    • Sakurai K, Nishiguchi N, Shirakawa O, et al. Lack of association between endoplasmic reticulum stress response genes and suicidal victims. Kobe J Med Sci 2007; 53(4): 151-5.
    • (2007) Kobe J Med Sci , vol.53 , Issue.4 , pp. 151-155
    • Sakurai, K.1    Nishiguchi, N.2    Shirakawa, O.3
  • 62
    • 36348930605 scopus 로고    scopus 로고
    • The role of brainderived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development
    • Hayashi A, Kasahara T, Iwamoto K, et al. The role of brainderived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development. J Biol Chem 2007; 282(47): 34525-34.
    • (2007) J Biol Chem , vol.282 , Issue.47 , pp. 34525-34534
    • Hayashi, A.1    Kasahara, T.2    Iwamoto, K.3
  • 63
    • 67650490973 scopus 로고    scopus 로고
    • Preliminary evidence on the association between XBP1-116C/G polymorphism and response to prophylactic treatment with valproate in bipolar disorders
    • Kim B, Kim CY, Lee MJ, Joo YH. Preliminary evidence on the association between XBP1-116C/G polymorphism and response to prophylactic treatment with valproate in bipolar disorders. Psychiatry Res 2009; 168(3): 209-12.
    • (2009) Psychiatry Res , vol.168 , Issue.3 , pp. 209-212
    • Kim, B.1    Kim, C.Y.2    Lee, M.J.3    Joo, Y.H.4
  • 64
    • 30344450371 scopus 로고    scopus 로고
    • A possible association between the -116C/G single nucleotide polymorphism of the XBP1 gene and lithium prophylaxis in bipolar disorder
    • Masui T, Hashimoto R, Kusumi I, et al. A possible association between the -116C/G single nucleotide polymorphism of the XBP1 gene and lithium prophylaxis in bipolar disorder. Int J Neuropsychopharmacol 2006; 9(1): 83-8.
    • (2006) Int J Neuropsychopharmacol , vol.9 , Issue.1 , pp. 83-88
    • Masui, T.1    Hashimoto, R.2    Kusumi, I.3
  • 65
    • 4344680004 scopus 로고    scopus 로고
    • X-box binding protein 1 (XBP1) C--116G polymorphisms in bipolar disorders and age of onset
    • Hou SJ, Yen FC, Cheng CY, Tsai SJ, Hong CJ. X-box binding protein 1 (XBP1) C--116G polymorphisms in bipolar disorders and age of onset. Neurosci Lett 2004; 367(2): 232-4.
    • (2004) Neurosci Lett , vol.367 , Issue.2 , pp. 232-234
    • Hou, S.J.1    Yen, F.C.2    Cheng, C.Y.3    Tsai, S.J.4    Hong, C.J.5
  • 66
    • 33645280897 scopus 로고    scopus 로고
    • XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells
    • Kakiuchi C, Ishiwata M, Hayashi A, Kato T. XBP1 induces WFS1 through an endoplasmic reticulum stress response element-like motif in SH-SY5Y cells. J Neurochem 2006; 97(2): 545-55.
    • (2006) J Neurochem , vol.97 , Issue.2 , pp. 545-555
    • Kakiuchi, C.1    Ishiwata, M.2    Hayashi, A.3    Kato, T.4
  • 67
    • 77949751415 scopus 로고    scopus 로고
    • Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells
    • Fonseca SG, Ishigaki S, Oslowski CM, et al. Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells. J Clin Invest 2010; 120(3): 744-55.
    • (2010) J Clin Invest , vol.120 , Issue.3 , pp. 744-755
    • Fonseca, S.G.1    Ishigaki, S.2    Oslowski, C.M.3
  • 68
    • 77949263646 scopus 로고    scopus 로고
    • Relationship between functional promoter polymorphism in the XBP1 gene (-116C/G) and atherosclerosis, ischemic stroke and hyperhomocysteinemia
    • Yilmaz E, Akar R, Eker ST, Deda G, Adiguzel Y, Akar N. Relationship between functional promoter polymorphism in the XBP1 gene (-116C/G) and atherosclerosis, ischemic stroke and hyperhomocysteinemia. Mol Biol Rep 2010; 37(1): 269-72.
    • (2010) Mol Biol Rep , vol.37 , Issue.1 , pp. 269-272
    • Yilmaz, E.1    Akar, R.2    Eker, S.T.3    Deda, G.4    Adiguzel, Y.5    Akar, N.6
  • 69
    • 27844476313 scopus 로고    scopus 로고
    • Relationship between XBP1 genotype and personality traits assessed by TCI and NEO-FFI
    • Kusumi I, Masui T, Kakiuchi C, et al. Relationship between XBP1 genotype and personality traits assessed by TCI and NEO-FFI. Neurosci Lett 2005; 391(1-2): 7-10.
    • (2005) Neurosci Lett , vol.391 , Issue.1-2 , pp. 7-10
    • Kusumi, I.1    Masui, T.2    Kakiuchi, C.3
  • 71
    • 33748362847 scopus 로고    scopus 로고
    • Association study of a functional promoter polymorphism of the X-box binding protein 1 gene in Japanese patients with schizophrenia
    • Watanabe Y, Fukui N, Muratake T, et al. Association study of a functional promoter polymorphism of the X-box binding protein 1 gene in Japanese patients with schizophrenia. Psychiatry Clin Neurosci 2006; 60(5): 633-5.
    • (2006) Psychiatry Clin Neurosci , vol.60 , Issue.5 , pp. 633-635
    • Watanabe, Y.1    Fukui, N.2    Muratake, T.3
  • 72
    • 30344435574 scopus 로고    scopus 로고
    • Association study of a functional promoter polymorphism in the XBP1 gene and schizophrenia
    • Jonsson EG, Cichon S, Schumacher J, et al. Association study of a functional promoter polymorphism in the XBP1 gene and schizophrenia. Am J Med Genet B Neuropsychiatr Genet 2006; 141B(1): 71-5.
    • (2006) Am J Med Genet B Neuropsychiatr Genet , vol.141 B , Issue.1 , pp. 71-75
    • Jonsson, E.G.1    Cichon, S.2    Schumacher, J.3
  • 73
    • 20344367034 scopus 로고    scopus 로고
    • The X-box binding protein 1 (XBP1) gene is not associated with methamphetamine dependence
    • Morita Y, Ujike H, Tanaka Y, et al. The X-box binding protein 1 (XBP1) gene is not associated with methamphetamine dependence. Neurosci Lett 2005; 383(1-2): 194-8.
    • (2005) Neurosci Lett , vol.383 , Issue.1-2 , pp. 194-198
    • Morita, Y.1    Ujike, H.2    Tanaka, Y.3
  • 74
    • 4243137322 scopus 로고    scopus 로고
    • Association of the XBP1-116C/G polymorphism with schizophrenia in the Japanese population
    • Kakiuchi C, Ishiwata M, Umekage T, et al. Association of the XBP1-116C/G polymorphism with schizophrenia in the Japanese population. Psychiatry Clin Neurosci 2004; 58(4): 438-40.
    • (2004) Psychiatry Clin Neurosci , vol.58 , Issue.4 , pp. 438-440
    • Kakiuchi, C.1    Ishiwata, M.2    Umekage, T.3
  • 75
    • 84912019376 scopus 로고    scopus 로고
    • Investigating the protective effect of lithium against high glucose-induced neurotoxicity in PC12 cells: Involvements of ROS, JNK and P38 MAPKs, and apoptotic mitochondria pathway
    • Aminzadeh A, Dehpour AR, Safa M, Mirzamohammadi S, Sharifi AM. Investigating the protective effect of lithium against high glucose-induced neurotoxicity in PC12 cells: involvements of ROS, JNK and P38 MAPKs, and apoptotic mitochondria pathway. Cell Mol Neurobiol 2014; 34(8): 1143-50.
    • (2014) Cell Mol Neurobiol , vol.34 , Issue.8 , pp. 1143-1150
    • Aminzadeh, A.1    Dehpour, A.R.2    Safa, M.3    Mirzamohammadi, S.4    Sharifi, A.M.5
  • 76
    • 84895948105 scopus 로고    scopus 로고
    • Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells
    • Palsamy P, Bidasee KR, Shinohara T. Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells. Exp Eye Res 2014; 121: 26-34.
    • (2014) Exp Eye Res , vol.121 , pp. 26-34
    • Palsamy, P.1    Bidasee, K.R.2    Shinohara, T.3
  • 77
    • 35648967718 scopus 로고    scopus 로고
    • eIF2B and oligodendrocyte survival: Where nature and nurture meet in bipolar disorder and schizophrenia?
    • Carter CJ. eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia? Schizophr Bull 2007; 33(6): 1343-53.
    • (2007) Schizophr Bull , vol.33 , Issue.6 , pp. 1343-1353
    • Carter, C.J.1
  • 78
    • 33846560734 scopus 로고    scopus 로고
    • Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: Implications for oligodendrocyte viability
    • Carter CJ. Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability. Neurochem Int 2007; 50(3): 461-90.
    • (2007) Neurochem Int , vol.50 , Issue.3 , pp. 461-490
    • Carter, C.J.1
  • 79
    • 84904156387 scopus 로고    scopus 로고
    • Valproate pretreatment protects pancreatic beta-cells from palmitate-induced ER stress and apoptosis by inhibiting glycogen synthase kinase-3beta
    • Huang S, Zhu M, Wu W, et al. Valproate pretreatment protects pancreatic beta-cells from palmitate-induced ER stress and apoptosis by inhibiting glycogen synthase kinase-3beta. J Biomed Sci 2014; 21: 38.
    • (2014) J Biomed Sci , vol.21 , pp. 38
    • Huang, S.1    Zhu, M.2    Wu, W.3
  • 80
    • 34247131282 scopus 로고    scopus 로고
    • Association analysis of ATF4 and ATF5, genes for interacting-proteins of DISC1, in bipolar disorder
    • Kakiuchi C, Ishiwata M, Nanko S, et al. Association analysis of ATF4 and ATF5, genes for interacting-proteins of DISC1, in bipolar disorder. Neurosci Lett 2007; 417(3): 316-21.
    • (2007) Neurosci Lett , vol.417 , Issue.3 , pp. 316-321
    • Kakiuchi, C.1    Ishiwata, M.2    Nanko, S.3
  • 82
    • 84881076550 scopus 로고    scopus 로고
    • CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis
    • Teske BF, Fusakio ME, Zhou D, et al. CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis. Mol Biol Cell 2013; 24(15): 2477-90.
    • (2013) Mol Biol Cell , vol.24 , Issue.15 , pp. 2477-2490
    • Teske, B.F.1    Fusakio, M.E.2    Zhou, D.3
  • 83
    • 84979517834 scopus 로고    scopus 로고
    • Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression
    • Matsumoto H, Miyazaki S, Matsuyama S, et al. Selection of autophagy or apoptosis in cells exposed to ER-stress depends on ATF4 expression pattern with or without CHOP expression. Biol Open 2013; 2(10): 1084-90.
    • (2013) Biol Open , vol.2 , Issue.10 , pp. 1084-1090
    • Matsumoto, H.1    Miyazaki, S.2    Matsuyama, S.3
  • 84
    • 80053952176 scopus 로고    scopus 로고
    • Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemiareperfusion injury
    • Zhang Z, Tong N, Gong Y, et al. Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemiareperfusion injury. Neurosci Lett 2011; 504(2): 88-92.
    • (2011) Neurosci Lett , vol.504 , Issue.2 , pp. 88-92
    • Zhang, Z.1    Tong, N.2    Gong, Y.3
  • 85
    • 0036524563 scopus 로고    scopus 로고
    • A mannosyltransferase gene at 11q23 is disrupted by a translocation breakpoint that co-segregates with bipolar affective disorder in a small family
    • Baysal BE, Willett-Brozick JE, Badner JA, et al. A mannosyltransferase gene at 11q23 is disrupted by a translocation breakpoint that co-segregates with bipolar affective disorder in a small family. Neurogenetics 2002; 4(1): 43-53.
    • (2002) Neurogenetics , vol.4 , Issue.1 , pp. 43-53
    • Baysal, B.E.1    Willett-Brozick, J.E.2    Badner, J.A.3
  • 87
    • 84873058959 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder
    • Chen DT, Jiang X, Akula N, et al. Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. Mol Psychiatry 2013; 18(2): 195-205.
    • (2013) Mol Psychiatry , vol.18 , Issue.2 , pp. 195-205
    • Chen, D.T.1    Jiang, X.2    Akula, N.3
  • 88
    • 84902515695 scopus 로고    scopus 로고
    • Genetic association of LMAN2L gene in schizophrenia and bipolar disorder and its interaction with ANK3 gene polymorphism
    • Lim CH, Zain SM, Reynolds GP, et al. Genetic association of LMAN2L gene in schizophrenia and bipolar disorder and its interaction with ANK3 gene polymorphism. Prog Neuropsychopharmacol Biol Psychiatry 2014; 54: 157-62.
    • (2014) Prog Neuropsychopharmacol Biol Psychiatry , vol.54 , pp. 157-162
    • Lim, C.H.1    Zain, S.M.2    Reynolds, G.P.3
  • 89
    • 0035058002 scopus 로고    scopus 로고
    • Serotonin-induced platelet intracellular calcium mobilization in various psychiatric disorders: Is it specific to bipolar disorder?
    • Suzuki K, Kusumi I, Sasaki Y, Koyama T. Serotonin-induced platelet intracellular calcium mobilization in various psychiatric disorders: is it specific to bipolar disorder? J Affect Disord 2001; 64(2-3): 291-6.
    • (2001) J Affect Disord , vol.64 , Issue.2-3 , pp. 291-296
    • Suzuki, K.1    Kusumi, I.2    Sasaki, Y.3    Koyama, T.4
  • 90
    • 0033792145 scopus 로고    scopus 로고
    • Treatment response in depressed patients with enhanced Ca mobilization stimulated by serotonin
    • Kusumi I, Suzuki K, Sasaki Y, Kameda K, Koyama T. Treatment response in depressed patients with enhanced Ca mobilization stimulated by serotonin. Neuropsychopharmacology 2000; 23(6): 690-6.
    • (2000) Neuropsychopharmacology , vol.23 , Issue.6 , pp. 690-696
    • Kusumi, I.1    Suzuki, K.2    Sasaki, Y.3    Kameda, K.4    Koyama, T.5
  • 91
    • 33845641229 scopus 로고    scopus 로고
    • Effects of calmodulin and protein kinase C modulators on transient Ca2+ increase and capacitative Ca2+ entry in human platelets: Relevant to pathophysiology of bipolar disorder
    • Akimoto T, Kusumi I, Suzuki K, Koyama T. Effects of calmodulin and protein kinase C modulators on transient Ca2+ increase and capacitative Ca2+ entry in human platelets: relevant to pathophysiology of bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 2007; 31(1): 136-41.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , Issue.1 , pp. 136-141
    • Akimoto, T.1    Kusumi, I.2    Suzuki, K.3    Koyama, T.4
  • 92
    • 33845641229 scopus 로고    scopus 로고
    • Effects of calmodulin and protein kinase C modulators on transient Ca2+ increase and capacitative Ca2+ entry in human platelets: Relevant to pathophysiology of bipolar disorder
    • Akimoto T, Kusumi I, Suzuki K, Koyama T. Effects of calmodulin and protein kinase C modulators on transient Ca2+ increase and capacitative Ca2+ entry in human platelets: relevant to pathophysiology of bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 2007; 31(1): 136-41.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , Issue.1 , pp. 136-141
    • Akimoto, T.1    Kusumi, I.2    Suzuki, K.3    Koyama, T.4
  • 93
    • 41049090988 scopus 로고    scopus 로고
    • Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder
    • Mathieu F, Miot S, Etain B, et al. Association between the PPP3CC gene, coding for the calcineurin gamma catalytic subunit, and bipolar disorder. Behav Brain Funct 2008; 4: 2.
    • (2008) Behav Brain Funct , vol.4 , pp. 2
    • Mathieu, F.1    Miot, S.2    Etain, B.3
  • 94
    • 33745095612 scopus 로고    scopus 로고
    • Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes
    • Beasley CL, Pennington K, Behan A, Wait R, Dunn MJ, Cotter D. Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes. Proteomics 2006; 6(11): 3414-25.
    • (2006) Proteomics , vol.6 , Issue.11 , pp. 3414-3425
    • Beasley, C.L.1    Pennington, K.2    Behan, A.3    Wait, R.4    Dunn, M.J.5    Cotter, D.6
  • 95
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet 2011; 43(10): 977-83.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 977-983
  • 96
    • 84940897894 scopus 로고    scopus 로고
    • Ca signalling in the endoplasmic reticulum/secretory granule microdomain
    • Petersen OH. Ca signalling in the endoplasmic reticulum/secretory granule microdomain. Cell Calcium 2015; 58(4): 397-404.
    • (2015) Cell Calcium , vol.58 , Issue.4 , pp. 397-404
    • Petersen, O.H.1
  • 97
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 2013; 381(9875): 1371-9.
    • (2013) Lancet , vol.381 , Issue.9875 , pp. 1371-1379
  • 98
    • 84878220679 scopus 로고    scopus 로고
    • Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC
    • Hamshere ML, Walters JT, Smith R, et al. Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Mol Psychiatry 2013; 18(6): 708-12.
    • (2013) Mol Psychiatry , vol.18 , Issue.6 , pp. 708-712
    • Hamshere, M.L.1    Walters, J.T.2    Smith, R.3
  • 99
    • 80053384370 scopus 로고    scopus 로고
    • Genome-wide association study identifies five new schizophrenia loci
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study identifies five new schizophrenia loci. Nat Genet 2011; 43(10): 969-76.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 969-976
  • 100
    • 79952959359 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia
    • Clay HB, Sillivan S, Konradi C. Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia. Int J Dev Neurosci 2011; 29(3): 311-24.
    • (2011) Int J Dev Neurosci , vol.29 , Issue.3 , pp. 311-324
    • Clay, H.B.1    Sillivan, S.2    Konradi, C.3
  • 101
    • 84925813310 scopus 로고    scopus 로고
    • Salubrinal, ER stress inhibitor, attenuates kainic acid-induced hippocampal cell death
    • Kim JS, Heo RW, Kim H, Yi CO, Shin HJ, Han JW, Roh GS. Salubrinal, ER stress inhibitor, attenuates kainic acid-induced hippocampal cell death. J Neural Transm 2014; 121(10): 1233-43.
    • (2014) J Neural Transm , vol.121 , Issue.10 , pp. 1233-1243
    • Kim, J.S.1    Heo, R.W.2    Kim, H.3    Yi, C.O.4    Shin, H.J.5    Han, J.W.6    Roh, G.S.7
  • 102
    • 78649316378 scopus 로고    scopus 로고
    • The rate of metabolic syndrome in euthymic Canadian individuals with bipolar I/II disorder
    • McIntyre RS, Woldeyohannes HO, Soczynska JK, et al. The rate of metabolic syndrome in euthymic Canadian individuals with bipolar I/II disorder. Adv Ther 2010; 27(11): 828-36.
    • (2010) Adv Ther , vol.27 , Issue.11 , pp. 828-836
    • McIntyre, R.S.1    Woldeyohannes, H.O.2    Soczynska, J.K.3
  • 103
    • 79957605136 scopus 로고    scopus 로고
    • Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
    • Fu S, Yang L, Li P, et al. Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 2011; 473(7348): 528-31.
    • (2011) Nature , vol.473 , Issue.7348 , pp. 528-531
    • Fu, S.1    Yang, L.2    Li, P.3
  • 104
    • 84946550842 scopus 로고    scopus 로고
    • Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging
    • Ghosh AK, Garg SK, Mau T, O’Brien M, Liu J, Yung R. Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging. J Gerontol A Biol Sci Med Sci 2015; 70(11): 1320-9.
    • (2015) J Gerontol A Biol Sci Med Sci , vol.70 , Issue.11 , pp. 1320-1329
    • Ghosh, A.K.1    Garg, S.K.2    Mau, T.3    O’Brien, M.4    Liu, J.5    Yung, R.6
  • 105
    • 84920385377 scopus 로고    scopus 로고
    • Chronic Sleep Fragmentation During the Sleep Period Induces Hypothalamic Endoplasmic Reticulum Stress and PTP1b-Mediated Leptin Resistance in Male Mice
    • Hakim F, Wang Y, Carreras A, et al. Chronic Sleep Fragmentation During the Sleep Period Induces Hypothalamic Endoplasmic Reticulum Stress and PTP1b-Mediated Leptin Resistance in Male Mice. Sleep 2015; 38(1): 31-40.
    • (2015) Sleep , vol.38 , Issue.1 , pp. 31-40
    • Hakim, F.1    Wang, Y.2    Carreras, A.3
  • 106
    • 84907189036 scopus 로고    scopus 로고
    • ER stress in adipocytes and insulin resistance: Mechanisms and significance
    • Khan S, Wang CH. ER stress in adipocytes and insulin resistance: mechanisms and significance. Mol Med Rep 2014; 10(5): 2234-40.
    • (2014) Mol Med Rep , vol.10 , Issue.5 , pp. 2234-2240
    • Khan, S.1    Wang, C.H.2
  • 107
    • 84908665169 scopus 로고    scopus 로고
    • ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development
    • Nakagawa H, Umemura A, Taniguchi K, et al. ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. Cancer Cell 2014; 26(3): 331-43.
    • (2014) Cancer Cell , vol.26 , Issue.3 , pp. 331-343
    • Nakagawa, H.1    Umemura, A.2    Taniguchi, K.3
  • 108
    • 84923347695 scopus 로고    scopus 로고
    • Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells
    • Thon M, Hosoi T, Yoshii M, Ozawa K. Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells. Sci Rep 2014; 4: 7096.
    • (2014) Sci Rep , vol.4 , pp. 7096
    • Thon, M.1    Hosoi, T.2    Yoshii, M.3    Ozawa, K.4
  • 109
    • 47249158198 scopus 로고    scopus 로고
    • Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum
    • Novosyadlyy R, Kurshan N, Lann D, Vijayakumar A, Yakar S, LeRoith D. Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum. Cell Death Differ 2008; 15(8): 1304-17.
    • (2008) Cell Death Differ , vol.15 , Issue.8 , pp. 1304-1317
    • Novosyadlyy, R.1    Kurshan, N.2    Lann, D.3    Vijayakumar, A.4    Yakar, S.5    LeRoith, D.6
  • 110
    • 79551718338 scopus 로고    scopus 로고
    • Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder
    • Pereira AC, McQuillin A, Puri V, et al. Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder. Am J Med Genet B Neuropsychiatr Genet 2011; 156(2): 177-87.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 , Issue.2 , pp. 177-187
    • Pereira, A.C.1    McQuillin, A.2    Puri, V.3
  • 111
    • 76049087190 scopus 로고    scopus 로고
    • Relationship between functional promoter polymorphism in the XBP1 gene (-116C/G) and obesity
    • Yilmaz E, Berberoglu M, Akar N. Relationship between functional promoter polymorphism in the XBP1 gene (-116C/G) and obesity. Clin Appl Thromb Hemost 2010; 16(1): 99-102.
    • (2010) Clin Appl Thromb Hemost , vol.16 , Issue.1 , pp. 99-102
    • Yilmaz, E.1    Berberoglu, M.2    Akar, N.3
  • 112
    • 84913572979 scopus 로고    scopus 로고
    • Peripheral markers of oxidative stress and antioxidative defense in euthymia of bipolar disorder - Gender and obesity effects
    • Bengesser SA, Lackner N, Birner A, et al. Peripheral markers of oxidative stress and antioxidative defense in euthymia of bipolar disorder - Gender and obesity effects. J Affect Disord 2014; 172C: 367-74.
    • (2014) J Affect Disord , vol.172 C , pp. 367-374
    • Bengesser, S.A.1    Lackner, N.2    Birner, A.3
  • 113
    • 84913526941 scopus 로고    scopus 로고
    • Oxidative stress in bipolar affective disorder
    • Reininghaus EZ, Zelzer S, Reininghaus B, et al. Oxidative stress in bipolar affective disorder. Nervenarzt 2014; 85: 1099-1107.
    • (2014) Nervenarzt , vol.85 , pp. 1099-1107
    • Reininghaus, E.Z.1    Zelzer, S.2    Reininghaus, B.3
  • 114
    • 84925231647 scopus 로고    scopus 로고
    • Treatment of bipolar depression: Making sensible decisions
    • Citrome L. Treatment of bipolar depression: making sensible decisions. CNS Spectr 2014; 19(Suppl 1): 4-11.
    • (2014) CNS Spectr , vol.19 , pp. 4-11
    • Citrome, L.1
  • 115
    • 84964074369 scopus 로고    scopus 로고
    • Konsensus-Statement _ State of the art 2013. CliniCum Neuropsy, Sonderausgabe
    • Kasper S, Kapfhammer HP, Bach M, et al. Bipolare Storungen. Konsensus-Statement _ State of the art 2013. CliniCum Neuropsy, Sonderausgabe, 2013.
    • (2013) Bipolare Storungen
    • Kasper, S.1    Kapfhammer, H.P.2    Bach, M.3
  • 116
    • 34548165477 scopus 로고    scopus 로고
    • Olanzapine potentiates neuronal survival and neural stem cell differentiation: Regulation of endoplasmic reticulum stress response proteins
    • Kurosawa S, Hashimoto E, Ukai W, Toki S, Saito S, Saito T. Olanzapine potentiates neuronal survival and neural stem cell differentiation: regulation of endoplasmic reticulum stress response proteins. J Neural Transm 2007; 114(9): 1121-8.
    • (2007) J Neural Transm , vol.114 , Issue.9 , pp. 1121-1128
    • Kurosawa, S.1    Hashimoto, E.2    Ukai, W.3    Toki, S.4    Saito, S.5    Saito, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.