Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder

Human Molecular Genetics

Volumn 15, Issue 21, 2006, Pages 3132-3145

  Abdolmaleky, Hamid Mostafavi ^a,b,c,d   Cheng, Kuang Hung ^b   Faraone, Stephen V ^e   Wilcox, Marsha ^a,b,f   Glatt, Stephen J ^g   Gao, Fangming ^b   Smith, Cassandra L ^d   Shafa, Rahim ^h   Aeali, Batol ^d   Carnevale, Julie ^b   Pan, Hongjie ^b   Papageorgis, Panagiotis ^b   Ponte, Jose F ^b   Sivaraman, Vadivelu ⁱ   Tsuang, Ming T ^a,g   Thiagalingam, Sam ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d Boston University   (United States)

^e State University of New York Upstate Medical University: College of Medicine   (United States)

^f BOSTON UNIVERSITY   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h METROWEST MEDICAL CENTER   (United States)

ⁱ UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE; DOPAMINE 1 RECEPTOR; MEMBRANE ENZYME; METHIONINE; MOOD STABILIZER; NEUROLEPTIC AGENT; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; AUTOPSY; BIPOLAR DISORDER; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; FRONTAL LOBE; GENE OVEREXPRESSION; GENETIC CORRELATION; GENETIC POLYMORPHISM; GENETIC RISK; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; RISK FACTOR; SCHIZOPHRENIA; STATISTICAL SIGNIFICANCE;

ALCOHOLISM; AMINO ACID SUBSTITUTION; ANTIPSYCHOTIC AGENTS; BIPOLAR DISORDER; CASE-CONTROL STUDIES; CATECHOL O-METHYLTRANSFERASE; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FRONTAL LOBE; GENETIC PREDISPOSITION TO DISEASE; HEART DISEASES; HUMANS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RECEPTORS, DOPAMINE D1; RISK FACTORS; SCHIZOPHRENIA;

EID: 33750244045     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl253     Document Type: Article

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