Salubrinal, ER stress inhibitor, attenuates kainic acid-induced hippocampal cell death

Journal of Neural Transmission

Volumn 121, Issue 10, 2014, Pages 1233-1243

  Kim, Jung Soo ^a   Heo, Rok Won ^b   Kim, Hwajin ^b   Yi, Chin ok ^b   Shin, Hyun Joo ^b   Han, Jong Woo ^b   Roh, Gu Seob ^b  

^a Inje University College of Medicine   (South Korea)

^b Gyeongsang National University School of Medicine   (South Korea)

Author keywords

ER stress; Mitochondrial apoptosis; Parkin; Salubrinal; Seizures

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 3; EUKARYOTIC TRANSLATION INITIATION FACTOR 2 ALPHA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HIPPOCALCIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INITIATION FACTOR; KAINIC ACID; PARKIN; PROTEIN BAX; PROTEIN BCL XL; SALUBRINAL; UNCLASSIFIED DRUG; ANTICONVULSIVE AGENT; CINNAMIC ACID DERIVATIVE; NEUROPROTECTIVE AGENT; NOS2 PROTEIN, MOUSE; THIOUREA; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CELL DEATH; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; EPILEPTIC STATE; EXPERIMENTAL EPILEPSY; EXPERIMENTAL SEIZURE; HIPPOCAMPAL CA3 REGION; INTRACELLULAR SIGNALING; MALE; MITOCHONDRION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SURVIVAL RATE; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; HIPPOCAMPUS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION; SEIZURES; SURVIVAL;

ANIMALS; ANTICONVULSANTS; APOPTOSIS; CINNAMATES; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HIPPOCAMPUS; KAINIC ACID; MALE; MICE, INBRED ICR; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE II; RANDOM ALLOCATION; SEIZURES; SURVIVAL ANALYSIS; THIOUREA; UBIQUITIN-PROTEIN LIGASES;

EID: 84925813310     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-014-1208-0     Document Type: Article

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