Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells

Neuropharmacology

Volumn 39, Issue 11, 2000, Pages 2162-2169

  Bown, Christopher D ^a   Wang, Jun Feng ^a   Young, L Trevor ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Anticonvulsants; Calreticulin; GRP78; GRP94; Mood stabilizers; Valproate

Indexed keywords

ANTICONVULSIVE AGENT; CALCIUM BINDING PROTEIN; CALRETICULIN; CHAPERONE; HEAT SHOCK PROTEIN; MESSENGER RNA; VALPROIC ACID;

AFFECTIVE NEUROSIS; ANIMAL CELL; ARTICLE; CELL CULTURE; DRUG EFFECT; ENDOPLASMIC RETICULUM; GENE CONTROL; GLIOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTIMANIC AGENTS; CALCIUM-BINDING PROTEINS; CALRETICULIN; ENDOPLASMIC RETICULUM; GENE EXPRESSION; HSP70 HEAT-SHOCK PROTEINS; MEMBRANE PROTEINS; RATS; RIBONUCLEOPROTEINS; RNA, RIBOSOMAL, 28S; TUMOR CELLS, CULTURED; VALPROIC ACID;

EID: 0033845743     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00029-0     Document Type: Article

References (32)

1. Asghari V., Wang J.F., Reiach J.S., Young L.T. Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells. Molecular Brain Research. 58:1998;95-102.
2. Bowden C.L., Brugger A.M., Swann A.C., Calabrese J.R., Janicak P.G., Petty F., Dilsaver S.C., Davis J.M., Rush A.J., Small J.G., Garza-Trevino E.S., Risch S.C., Goodnick P.J., Morris D.D. Efficacy of dialproex vs lithium and placebo in the treatment of mania. Journal of the American Medical Association. 271:1994;918-924.
3. Bowden C.L., Janicak P.G., Orsulak P., Swann A.C., Davis J.M., Calabrese J.R., Goodnick P., Small J.G., Rush A.J., Kimmel S.E., Risch S.C., Morris D.D. Relation of serum valproate concentration to response in mania. American Journal of Psychiatry. 153:1996;765-770.
4. 2+ stores. Journal of Biological Chemistry. 266:1991;7037-7043.
5. 2+ binding to control of gene expression. Trends in Cell Biology. 4:1994;152-154.
6. Chen G., Manji H.K., Hawver D.B., Wright C.B., Potter W.Z. Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro. Journal of Neurochemistry. 63:1994;2361-2364.
7. Chen G., Manji H.K., Wright C.B., Hawver D., Potter W.Z. Effects of valproic acid on β-adrenergic receptors, G proteins and adenylyl-cyclase in rat C6 glioma cells. Neuropsychopharmacology. 15:1996;271-280.
8. Chen G., Yuan P., Hawver D.B., Potter W.Z., Manji H.K. Increase in AP-1 transcription factor DNA binding activity by valproic acid. Neuropsychopharmacology. 16:1997;238-245.
9. Chen G., Zeng W.Z., Yuan P.X., Huang L.D., Jiang Y.M., Zhao Z.H., Manji H.K. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. Journal of Neurochemistry. 72:1999;879-882.
10. Chen G., Yuan P.X., Jiang Y.M., Huang L.D., Manji H.K. Valproate robustly enhances AP-1 mediated gene expression. Molecular Brain Research. 64:1999;52-58.
11. Doutheil J., Gissel C., Oschlies U., Hossmann K.A., Paschen W. Relation of neuronal endoplasmic reticulum calcium homeostasis to ribosomal aggregation and protein synthesis: implications for stress-induced suppression of protein synthesis. Brain Research. 775:1997;43-51.
12. Fliegel L., Burns K., MacLennan D.H., Reithmeier R.A., Michalak M. Molecular cloning of the high affinity calcium-binding protein (calreticulin) of skeletal muscle sarcoplasmic reticulum. Journal of Biological Chemistry. 264:1989;21522-21528.
13. Gething M.-J. Guidebook to Molecular Chaperones and Protein-Folding Catalysts. 1997;Oxford University Press, Oxford.
14. Gething M.J., Sambrook J. Protein folding in the cell. Nature. 355:1992;33-45.
15. Johnson R.J., Liu N.G., Fishman J.B., Dixon J.D., Fine R.E. Isolation of a calreticulin-like calcium binding protein from bovine brain. Molecular Brain Research. 12:1992;69-76.
16. Lee A.S., Delegeane A.M., Baker V., Chow P.C. Transcriptional regulation of two genes specifically induced by glucose starvation in a hamster mutant fibroblast cell line. Journal of Biological Chemistry. 258:1983;597-603.
17. Lenox R.H., McNamara R.K., Watterson J.M., Watson D.G. Myristoylated alanine-rich C kinase substrate (MARCKS): a molecular target for the therapeutic action of mood stabilizers in the brain? Journal of Clinical Psychiatry. 57(Suppl. 13):1996;23-31.
18. 2+. Journal of Biological Chemistry. 272:1997;12003-12009.
19. 2+ disturbances, and cell death in renal epithelial cells. Journal of Biological Chemistry. 272:1997;21751-21759.
20. Martin M.L., Regan C.M. The anticonvulsant valproate teratogen restricts the glial cell cycle at a defined point in the mid-G1 phase. Brain Research. 554:1991;223-228.
21. McCauliffe D.P., Yang Y.S., Wilson J., Sontheimer R.D., Capra J.D. The 5′-flanking region of the human calreticulin gene shares homology with the human GRP78, GRP94, and protein disulfide isomerase promoters. Journal of Biological Chemistry. 267:1992;2557-2562.
22. 2+ binding proteins and member of the thioredoxin superfamily. Journal of Biological Chemistry. 269:1994;1744-1749.
23. Pope H.G., McElroy S.L., Keck P.E., Hudson J.I. Valproate in the treatment of acute mania. Archives of General Psychiatry. 48:1991;62-68.
24. Post R.M. Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. American Journal of Psychiatry. 149:1992;999-1010.
25. Regan R.F., Panter S.S., Witz A., Tilly J.L., Giffard R.G. Ultrastructure of excitotoxic neuronal death in murine cortical culture. Brain Research. 705:1995;188-198.
26. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proceedings of the National Academy of Sciences USA. 74:1977;5463-5467.
27. Wang J.F., Young L.T. Differential display PCR reveals increased expression of 2′,3′ cyclic nucleotide 3′-phosphodiesterase by lithium. Federation of the European Biochemical Societies Letters. 386:1996;225-229.
28. Wang J.F., Bown C., Young L.T. Differential display PCR reveals novels targets for the mood stabilizing drug valproate including the molecular chaperone, glucose-regulated protein 78. Molecular Pharmacology. 55:1999;521-527.
29. Waser M., Mesaeli N., Spencer C., Michalak M. Regulation of calreticulin gene expression by calcium. Journal of Cell Biology. 138:1997;547-557.
30. Watson D.G., Watterson J.M., Lenox R.H. Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: a property of protein kinase C-mediated mood stabilizers. Journal of Pharmacology and Experimental Therapeutics. 285:1998;307-316.
31. Yoshida H., Haze K., Yanagi H., Yura T., Mori K. Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Journal of Biological Chemistry. 273:1998;33741-33749.
32. Yu Z., Luo H., Fu W., Mattson M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Experimental Neurology. 155:1999;302-314.