Progress and prospects on DENV protease inhibitors

European Journal of Medicinal Chemistry

Volumn 117, Issue , 2016, Pages 125-143

  Timiri, Ajay Kumar ^a   Sinha, Barij Nayan ^a   Jayaprakash, Venkatesan ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Dengue; HTS; HTVS; Natural products; NS2BeNS3 protease; Peptide conjugates; Peptide inhibitors; Proteolytic mechanism; Small molecule inhibitors

Indexed keywords

CYCLOPEPTIDE; PEPTIDOMIMETIC AGENT; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; CYSTEINE PROTEINASE; NS2-3 PROTEASE; PROTEINASE INHIBITOR;

COMBINATORIAL LIBRARY; DENGUE VIRUS; DENGUE VIRUS 2; DENGUE VIRUS 3; IC50; INHIBITION CONSTANT; NONHUMAN; PROTEIN DEGRADATION; RATE CONSTANT; REVIEW; STRUCTURE ACTIVITY RELATION; CHEMISTRY; DENGUE; DRUG DESIGN; DRUG EFFECTS; ENZYMOLOGY; HUMAN; VIRUS REPLICATION;

CYSTEINE ENDOPEPTIDASES; DENGUE; DENGUE VIRUS; DRUG DESIGN; HUMANS; PROTEASE INHIBITORS; VIRUS REPLICATION;

EID: 84963808195     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2016.04.008     Document Type: Short Survey

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